Maciej Lalowski

Adjunct Professor

  • PL 63 (Haartmaninkatu 8)

    00014

    Finland

  • Viikinkaari 5, Biocenter 2

    00790 Helsinki

    Finland

19962021
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Publications 1996 2019

2019

Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells

Pham, D. D., Bruelle, C., Do, H. T., Pajanoja, C., Jin, C., Olkkonen, V. M., Eriksson-Rosenberg, O., Jauhiainen, M., Lalowski, M. & Lindholm, D., 11 Jul 2019, In : Cell Death and Disease. 10, 15 p., 537.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Functional analysis of synovial fluid from osteoarthritic knee and carpometacarpal joints unravels different molecular profiles

Barreto, G., Soliymani, R., Baumann, M., Waris, E., Eklund, K. K., Zenobi-Wong, M. & Lalowski, M., May 2019, In : Rheumatology. 58, 5, p. 897-907 11 p.

Research output: Contribution to journalArticleScientificpeer-review

HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells.

Arasu, U. T., Deen, A. J., Pasonen-Seppänen, S., Heikkinen, S., Lalowski, M., Kärnä, R., Härkönen, K., Mäkinen, P., Lazaro Ibañez, E., Siljander, P., Oikari, S., Levonen, A-L. & Rilla, K., 9 Dec 2019, In : Cellular and Molecular Life Sciences.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Muscle and serum metabolomes are dysregulated in colon-26 tumor-bearing mice despite amelioration of cachexia with activin receptor type 2B ligand blockade

Lautaoja, J. H., Lalowski, M., Nissinen, T. A., Hentila, J., Shi, Y., Ritvos, O., Cheng, S. & Hulmi, J. J., May 2019, In : American Journal of Physiology: Endocrinology and Metabolism. 316, 5, p. E852-E865 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2018
Open Access
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Estrogen regulates muscle bioenergetic signaling

Laakkonen, E. K., Soliymani, R. & Lalowski, M., 4 Feb 2018, In : Aging. 10, 2, p. 160-161 2 p.

Research output: Contribution to journalEditorialScientific

Open Access
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Lactate-Induced Glucose Output Is Unchanged by Metformin at a Therapeutic Concentration - A Mass Spectrometry Imaging Study of the Perfused Rat Liver

Calza, G., Nyberg, E., Mäkinen, M., Soliymani, R., Cascone, A., Lindholm, D., Barborini, E., Baumann, M., Lalowski, M. & Eriksson, O., 22 Feb 2018, In : Frontiers in Pharmacology. 9, 12 p., 141.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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SETBP1 induces transcription of a network of development genes by acting as an epigenetic hub

Piazza, R., Magistroni, V., Redaelli, S., Mauri, M., Massimino, L., Sessa, A., Peronaci, M., Lalowski, M., Soliymani, R., Mezzatesta, C., Pirola, A., Banfi, F., Rubio, A., Rea, D., Stagno, F., Usala, E., Martino, B., Campiotti, L., Merli, M., Passamonti, F. & 7 others, Onida, F., Morotti, A., Pavesi, F., Bregni, M., Broccoli, V., Baumann, M. & Gambacorti-Passerini, C., 6 Jun 2018, In : Nature Communications. 9, 13 p., 2192.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2017

Commentary: LACTB is a tumour suppressor that modulates lipid metabolism and cell state

Eriksson, O., Lalowski, M. & Lindholm, D., 2017, In : Frontiers in Physiology. 8, 3 p., 396.

Research output: Contribution to journalComment/debateScientificpeer-review

Open Access
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Estrogenic regulation of skeletal muscle proteome: a study of premenopausal women and postmenopausal MZ cotwins discordant for hormonal therapy

Laakkonen, E. K., Soliymani, R., Karvinen, S., Kaprio, J., Kujala, U. M., Baumann, M., Sipilä, S., Kovanen, V. & Lalowski, M., Dec 2017, In : Aging Cell. 16, 6, p. 1276-1287 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Recent advances in applying mass spectrometry and systems biology to determine brain dynamics

Scifo, E., Calza, G., Fuhrmann, M., Soliymani, R., Baumann, M. & Lalowski, M., 1 Jun 2017, In : Expert review of proteomics.. 14, 6, p. 545-559 15 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

The Networks of Genes Encoding Palmitoylated Proteins in Axonal and Synaptic Compartments Are Affected in PPT1 Overexpressing Neuronal-Like Cells

Pezzini, F., Bianchi, M., Benfatto, S., Griggio, F., Doccini, S., Carrozzo, R., Dapkunas, A., Delledonne, M., Santorelli, F. M., Lalowski, M. M. & Simonati, A., 22 Aug 2017, In : Frontiers in Molecular Neuroscience. 10, 18 p., 266.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Transcriptomic Profiling Discloses Molecular and Cellular Events Related to Neuronal Differentiation in SH-SY5Y Neuroblastoma Cells

Pezzini, F., Bettinetti, L., Di Leva, F., Bianchi, M., Zoratti, E., Carrozzo, R., Santorelli, F. M., Delledonne, M., Lalowski, M. & Simonati, A., May 2017, In : Cellular and Molecular Neurobiology. 37, 4, p. 665-682 18 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2016

Label-Free LC-MS/MS Comparative Analysis of Protein S-Nitrosome in Synaptosomes from Wild-Type and APP Transgenic Mice

Zareba-Koziol, M., Lalowski, M. & Wyslouch-Cieszynska, A., May 2016, Analysis of Post-Translational Modifications and Proteolysis in Neuroscience. Grant, J. E. & Li, H. (eds.). Humana press, p. 73-96 24 p. (Neuromethods; no. 114).

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Peroxisome proliferator-activated receptor-gamma coactivator-1 alpha mediates neuroprotection against excitotoxic brain injury in transgenic mice: role of mitochondria and X-linked inhibitor of apoptosis protein

Mäkelä, J., Mudo, G., Pham, D. D., Di Liberto, V., Eriksson, O., Louhivuori, L., Bruelle, C., Soliymani, R., Baumann, M., Korhonen, L., Lalowski, M., Belluardo, N. & Lindholm, D., Mar 2016, In : European Journal of Neuroscience. 43, 5, p. 626-639 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Proteomic Profiling in the Brain of CLN1 Disease Model Reveals Affected Functional Modules

Tikka, S., Monogioudi, E., Gotsopoulos, A., Soliymani, R., Pezzini, F., Scifo, E., Uusi-Rauva, K., Tyynelä, J., Baumann, M. H., Jalanko, A., Simonati, A. & Lalowski, M. M., 22 Mar 2016, In : NeuroMolecular Medicine. 18, 1, p. 109-133

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2015

MALDI-Imaging Mass Spectrometry on Tissues

Mainini, V., Lalowski, M., Gotsopoulos, A., Bitsika, V., Baumann, M. & Magni, F., 2015, Clinical Proteomics: Methods and Protocols. Vlahou, A. & Makridakis, M. (eds.). 2nd. ed. ed. Totowa, NJ: Humana press, p. 139-164 26 p. (Methods in Molecular Biology; vol. 1243).

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Proteomic analysis of the palmitoyl protein thioesterase 1 interactome in SH-SY5Y human neuroblastoma cells

Scifo, E., Szwajda, A., Soliymani, R., Pezzini, F., Bianchi, M., Dapkunas, A., Debski, J., Uusi-Rauva, K., Dadlez, M., Gingras, A-C., Tyynelä, J., Simonati, A., Jalanko, A., Baumann, M. H. & Lalowski, M., 18 Jun 2015, In : Journal of Proteomics. 123, p. 42-53 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Quantitative analysis of PPT1 interactome in human neuroblastoma cells

Scifo, E., Szwajda, A., Soliymani, R., Pezzini, F., Bianchi, M., Dapkunas, A., Debski, J., Uusi-Rauvala, K., Dadlez, M., Gingras, A-C., Tyynelä, J., Simonati, A., Jalanko, A., Baumann, M. & Lalowski, M., 2015, In : Data in Brief. 4, p. 207-216 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins

Hosp, F., Vossfeldt, H., Heinig, M., Vasiljevic, D., Arumughan, A., Wyler, E., Landthaler, M., Hubner, N., Wanker, E. E., Lannfelt, L., Ingelsson, M., Lalowski, M., Voigt, A., Selbach, M. & Genetic & Environm Risk Alzheimer', 19 May 2015, In : Cell Reports. 11, 7, p. 1134-1146 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2014

Global Analysis of S-nitrosylation Sites in the Wild Type (APP) Transgenic Mouse Brain-Clues for Synaptic Pathology

Zareba-Koziol, M., Szwajda, A., Dadlez, M., Wyslouch-Cieszynska, A. & Lalowski, M., Sep 2014, In : Molecular & Cellular Proteomics. 13, 9, p. 2288-2305 18 p.

Research output: Contribution to journalArticleScientificpeer-review

2013

Cathepsin D deficiency induces cytoskeletal changes and affects cell migration pathways in the brain

Koch, S., Scifo, E., Rokka, A., Trippner, P., Lindfors, M., Korhonen, R., Corthals, G. L., Virtanen, I., Lalowski, M. & Tyynelä, J., Feb 2013, In : Neurobiology of Disease. 50, p. 107-119 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Drafting the CLN3 Protein Interactome in SH-SY5Y Human Neuroblastoma Cells: A Label-free Quantitative Proteomics Approach

Scifo, E., Szwajda, A., Debski, J., Uusi-Rauva, K., Kesti, T., Dadlez, M., Gingras, A-C., Tyynelä, J., Baumann, M. H., Jalanko, A. & Lalowski, M., May 2013, In : Journal of Proteome Research. 12, 5, p. 2101-2115 15 p.

Research output: Contribution to journalArticleScientificpeer-review

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Imaging mass spectrometry: a new tool for kidney disease investigations

Lalowski, M., Magni, F., Mainini, V., Monogioudi, E., Gotsopoulos, A., Soliymani, R., Chinello, C. & Baumann, M., Jul 2013, In : Nephrology, Dialysis, Transplantation. 28, 7, p. 1648-1656 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Proteomics imaging and the kidney

Magni, F., Lalowski, M., Mainini, V., Marchetti-Deschmann, M., Chinello, C., Urbani, A. & Baumann, M., 2013, In : JN : Journal of Nephrology. 26, 3, p. 430-436 7 p.

Research output: Contribution to journalArticleScientificpeer-review

The Arctic AβPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated Aβ

Kalimo, H. O., Lalowski, M., Bogdanovic, N., Philipson, O., Bird, T. D., Nochlin, D., Schellenberg, G. D., Brundin, R., Olofsson, T., Soliymani, R., Baumann, M., Wirths, O., Bayer, T. A., Nilsson, L. NG., Basun, H., Lannfelt, L. & Ingelsson, M., 2013, In : Acta Neuropathologica Communications. 1, 1, p. 60 19 p.

Research output: Contribution to journalArticleScientificpeer-review

Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1-PP2A protein complex

Krauss, S., Griesche, N., Jastrzebska, E., Chen, C., Rutschow, D., Achmueller, C., Dorn, S., Boesch, S. M., Lalowski, M., Wanker, E., Schneider, R. & Schweiger, S., Feb 2013, In : Nature Communications. 4, p. Article Number: 1511 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2012

Caloric Restriction Ameliorates Angiotensin II-Induced Mitochondrial Remodeling and Cardiac Hypertrophy

Finckenberg, P., Eriksson-Rosenberg, O., Baumann, M., Merasto, S., Lalowski, M. M., Levijoki, J., Haasio, K., Kyto, V., Muller, D. N., Luft, F. C., Oresic, M. & Mervaala, E., 2012, In : Hypertension Research. 59, p. 76-84 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Phosphorylation-regulated axonal dependent transport of syntaxin 1 is mediated by a Kinesin-1 adapter

Chua, J. J. E., Butkevich, E., Worseck, J. M., Kittelmann, M., Gronborg, M., Behrmann, E., Stelzl, U., Pavlos, N. J., Lalowski, M. M., Eimer, S., Wanker, E. E., Klopfenstein, D. R. & Jahn, R., 10 Apr 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 15, p. 5862-5867 6 p.

Research output: Contribution to journalArticleScientificpeer-review

The Arctic amyloid-beta precursor protein (A beta PP) mutation results in distinct plaques and accumulation of N- and C-truncated A beta

Philipson, O., Lord, A., Lalowski, M., Soliymani, R., Baumann, M., Thyberg, J., Bogdanovic, N., Olofsson, T., Tjernberg, L. O., Ingelsson, M., Lannfelt, L., Kalimo, H. & Nilsson, L. N. G., 2012, In : Neurobiology of Aging. 33, 5, p. 1010 13 p.

Research output: Contribution to journalArticleScientificpeer-review

2011

Systems biology approaches towards Neuronal ceroid lipofuscinoses interactome

Scifo, E., Mia-Lisa, S., Uusi-Rauva, K., Soliymani, R., Karjalainen, M., Kyttala, A., Baumann, M., Jalanko, A. & Lalowski, M., 2011, In : The FEBS Journal. 278, p. 151-151 1 p.

Research output: Contribution to journalArticleScientificpeer-review

2001

Characterization of human palladin, a microfilament-associated protein

Mykkanen, O. M., Gronholm, M., Ronty, M., Lalowski, M., Salmikangas, P., Suila, H. & Carpen, O., 2001, In : Molecular Biology of the Cell. 12, p. 3060-3073 14 p.

Research output: Contribution to journalArticleScientificpeer-review

1998

HB-GAM, a novel amyloid associated protein, is present in prion related disorders and other cerebral amyloidoses

Lalowski, M., Baumann, M., Rauvala, H., Frangione, B. & Wisniewski, T., 1998, In : Advances in Behavioral Biology. p. 121-131

Research output: Contribution to journalArticleScientificpeer-review

1996

HB-GAM is a cytokine present in Alzheimer's and Down's syndrome lesions

Wisniewski, T., Lalowski, M., Baumann, M., Rauvala, H., Raulo, E., Nolo, R. & Frangione, B., 1996, In : NeuroReport. 7, p. 667-671

Research output: Contribution to journalArticleScientificpeer-review