Maija Castrén

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Phone0294125771, 0504482117, +358504482117, +358294125771
EmailMaija.Castrenhelsinkifi, maija.castrenhelsinkifi

PL 63 (Haartmaninkatu 8), C101b
HELSINGIN YLIOPISTO
Finland
PL 63 (Haartmaninkatu 8)
00014
Finland
Finland

Research activity per year

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External positions

Visiting Scholar, School of Medicine, University of California, Riverside

1 Oct 2019 → 30 Apr 2020

Fields of Science

3112 Neurosciences
neural stem cells
glutamate receptors
Neurotrophic factors
Development
clinical medicine
1184 Genetics, developmental biology, physiology

51 Article
10 Chapter
5 Review Article
2 Conference contribution
More

An iPSC-derived astrocyte model of fragile X syndrome exhibits dysregulated cholesterol homeostasis
Talvio, K., Wagner, V. A., Minkeviciene, R., Kirkwood, J. S., Kulinich, A. O., Umemori, J., Bhatia, A., Hur, M., Kakela, R., Ethell, I. M. & Castren, M. L., 29 Jul 2023, In: Communications Biology. 6, 1, 11 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Reduced LYNX1 expression in transcriptome of human iPSC-derived neural progenitors modeling fragile X syndrome
Talvio, K., Minkeviciene, R., Townsley, K. G., Achuta, V. S., Huckins, L. M., Corcoran, P., Brennand, K. & Castrén, M., Nov 2022, In: Frontiers in Cell and Developmental Biology. 10, 1034679.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Autismikirjon häiriöt
Translated title of the contribution: Clinical Neuropsychiatry; Autism spectrum disorderCastrén, M., Grönfors, S., Timonen, T. & Tani, P., 1 Jan 2021, Kliininen neuropsykiatria. Juva, K., Hublin, C., Kalska, H., Korkeila, J., Sainio, M. & Tani, P. (eds.). 2. uud. p. ed. Helsinki: Kustannusosakeyhtiö Duodecim, p. 295-319 25 p.
Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional
Generation of the Human Pluripotent Stem-Cell-Derived Astrocyte Model with Forebrain Identity
Peteri, U-K., Pitkonen, J., Utami, K. H., Paavola, J., Roybon, L., Pouladi, M. A. & Castren, M. L., Feb 2021, In: Brain Sciences. 11, 2, 14 p., 209.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Increased iron content in the heart of the Fmr1 knockout mouse
Talvio, K., Kanninen, K. M., White, A. R., Koistinaho, J. & Castren, M. L., Aug 2021, In: BioMetals. 34, 4, p. 947-954 8 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File

3 Finished

iNeuroPsych: iPSCs IN NEUROPSYCHOPHARMACOLOGY AND NEUROPSYCHIATRIC DISORDERS CLUSTER
Castrén, M.
13/05/2020 → 30/09/2020
Project: Other project
Contribution of astrocytes to beneficial responses of lovastatin in fragile X syndrome
Castrén, M.
Fraxa Research Foundation, Arvo ja Lea Ylppö Säätiö
01/06/2019 → 31/05/2020
Project: Research project
NeuroASD: Activity dependent defects of Neuronal specification and circuit formation in Autism Spectrum Disorders
Castrén, M.
01/02/2018 → 31/03/2018
Project: Other project

Fragile X urine microRNA profiling
Castrén, M. (Creator) & Laiho, A. (Producer), NCBI GEO, 9 Jan 2020
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE143347
Dataset
Functional changes of AMPA responses in human induced pluripotent stem cell-derived neural progenitors in fragile X syndrome
Castrén, M. (Creator) & Achuta, V. S. (Contributor), NCBI GEO, 18 Sep 2017
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE103965
Dataset
Reduced LYNX1 and epilepsy phenotype-related changes in transcriptome of human iPSC-derived neural progenitors modeling fragile X syndrome
Castrén, M. (Owner) & Corcoran, P. (Contributor), NCBI GEO, 2022
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE216875
Dataset

EVO grant for encouragement of scientific studies
Castrén, Maija (Recipient), 1999
Prize: Prizes and awards
Fogarty fellowship
Castren, Maija (Recipient) & Castrén, Maija (Recipient), 1986
Prize: Prizes and awards
FRAXA RESEARCH FELLOWSHIP GRANT
Castrén, Maija (Recipient), 2019
Prize: Prizes and awards
FRAXA Research grant
Castrén, Maija (Recipient), 2020
Prize: Prizes and awards
Max-Planck Scholarship
Castren, Maija (Recipient) & Castrén, Maija (Recipient), 1990
Prize: Prizes and awards

Autismitutkimus Suomessa
Maija Castrén (Speaker)
22 Apr 2022
Activity: Talk or presentation types › Invited talk
Human iPSC-derived astrocytes in studies elucidating contribution of astrocytes to impaired neuronal function in neurodevelopmental diseases
Maija Castrén (Speaker)
15 Jun 2022 → 17 Jun 2022
Activity: Talk or presentation types › Invited talk
Contribution of astrocytes to impaired neuronal function in fragile X syndrome
Maija Castrén (Speaker)
14 Jun 2022
Activity: Talk or presentation types › Oral presentation
Expert Evaluator for Marie Sklodowska-Curie Actions Posdoctoral Felloships programme
Maija Castrén (Consultant)
2021
Activity: Consultancy types › Consultancy
Childhood-onset genetic white matter disorders of the brain in Northern Finland
Maija Castrén (Pre-examiner)
May 2021
Activity: Examination types › Pre-examiner of doctoral thesis

Kantasolututkimuksesta apua perinnöllisen kehitysvamman ja autismin hoitoon
Maija Castrén
23/04/2020
1 Media contribution
Press/Media: Press / Media
Cholesterol-Dependent Changes in Fragile X Astrocytes
Maija Castrén
01/03/2020
1 Media contribution
Press/Media: Press / Media
Autismin kirjolla - monimuotoisia häiriöitä, kehityksellisiä ongelmia, mutta myös erityislahjakkuutta
Maija Castrén
07/05/2019
1 item of Media coverage
Press/Media: Press / Media
Altered Progenitor Cell Signaling Linked to Autism
Maija Castrén
04/12/2018
1 item of Media coverage
Press/Media: Press / Media
A Study Connects the Genetic Background of ASD with Stem Cell Dysfunction
Maija Castrén
04/12/2018
1 item of Media coverage
Press/Media: Press / Media

Maija Castrén, Senior Researcher

Personal profile

External positions

Fields of Science

International and National Collaboration

Dive into details

An iPSC-derived astrocyte model of fragile X syndrome exhibits dysregulated cholesterol homeostasis

Reduced LYNX1 expression in transcriptome of human iPSC-derived neural progenitors modeling fragile X syndrome

Autismikirjon häiriöt

Generation of the Human Pluripotent Stem-Cell-Derived Astrocyte Model with Forebrain Identity

Increased iron content in the heart of the Fmr1 knockout mouse

iNeuroPsych: iPSCs IN NEUROPSYCHOPHARMACOLOGY AND NEUROPSYCHIATRIC DISORDERS CLUSTER

Contribution of astrocytes to beneficial responses of lovastatin in fragile X syndrome

NeuroASD: Activity dependent defects of Neuronal specification and circuit formation in Autism Spectrum Disorders

Fragile X urine microRNA profiling

Functional changes of AMPA responses in human induced pluripotent stem cell-derived neural progenitors in fragile X syndrome

Reduced LYNX1 and epilepsy phenotype-related changes in transcriptome of human iPSC-derived neural progenitors modeling fragile X syndrome

EVO grant for encouragement of scientific studies

Fogarty fellowship

FRAXA RESEARCH FELLOWSHIP GRANT

FRAXA Research grant

Max-Planck Scholarship

Autismitutkimus Suomessa

Human iPSC-derived astrocytes in studies elucidating contribution of astrocytes to impaired neuronal function in neurodevelopmental diseases

Contribution of astrocytes to impaired neuronal function in fragile X syndrome

Expert Evaluator for Marie Sklodowska-Curie Actions Posdoctoral Felloships programme

Childhood-onset genetic white matter disorders of the brain in Northern Finland

Kantasolututkimuksesta apua perinnöllisen kehitysvamman ja autismin hoitoon

Cholesterol-Dependent Changes in Fragile X Astrocytes

Autismin kirjolla - monimuotoisia häiriöitä, kehityksellisiä ongelmia, mutta myös erityislahjakkuutta

Altered Progenitor Cell Signaling Linked to Autism

A Study Connects the Genetic Background of ASD with Stem Cell Dysfunction

Maija Castrén, Senior Researcher

Personal profile

External positions

Fields of Science

International and National Collaboration

Publications

Projects

Datasets

Prizes

Activities

Press/Media