Research output per year
Research output per year
Personal profile
External positions
Visiting Scholar, School of Medicine, University of California, Riverside
1 Oct 2019 → 30 Apr 2020
Fields of Science
- 3112 Neurosciences
- neural stem cells
- glutamate receptors
- Neurotrophic factors
- Development
- clinical medicine
- 1184 Genetics, developmental biology, physiology
International and National Collaboration
Publications and projects within past five years.
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Astrocytes in fragile X syndrome
Talvio, K. V. J. & Castrén, M. L., 8 Jan 2024, In: Frontiers in Cellular Neuroscience. 17, 9 p., 1322541.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
An iPSC-derived astrocyte model of fragile X syndrome exhibits dysregulated cholesterol homeostasis
Talvio, K., Wagner, V. A., Minkeviciene, R., Kirkwood, J. S., Kulinich, A. O., Umemori, J., Bhatia, A., Hur, M., Kakela, R., Ethell, I. M. & Castren, M. L., 29 Jul 2023, In: Communications Biology. 6, 1, 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Astrosyyttien kolesterolihäiriö FraX-oireyhtymässä
Talvio, K. V. J., Wagner, V. A., Minkeviciene, R., Kirkwood, J. S., Kulinich, A. O., Umemori, J., Bhatia, A., Hur, M., Käkelä, R., Ethell, I. & Castrén, M. L., 2023, In: Duodecim. 139, 17, p. 1406 1 p.Research output: Contribution to journal › Comment/debate › Professional
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Indusoidut kantasolut neuropsykiatristen sairauksien tutkimuksessa
Castrén, M. L., 2023, In: Duodecim. 139, 10, p. 827-827 1 p.Research output: Contribution to journal › Comment/debate › Professional
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Intellectual disabilities moderate sex/gender differences in autism spectrum disorder: a systematic review and meta-analysis
Saure, E., Castren, M., Mikkola, K. & Salmi, J., Jan 2023, In: Journal of Intellectual Disability Research. 67, 1, p. 1-34 34 p.Research output: Contribution to journal › Review Article › peer-review
Open AccessFile
Projects
- 3 Finished
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iNeuroPsych: iPSCs IN NEUROPSYCHOPHARMACOLOGY AND NEUROPSYCHIATRIC DISORDERS CLUSTER
13/05/2020 → 30/09/2020
Project: Other project
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Contribution of astrocytes to beneficial responses of lovastatin in fragile X syndrome
Arvo ja Lea Ylppö Säätiö, Fraxa Research Foundation
01/06/2019 → 31/05/2020
Project: Research project
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NeuroASD: Activity dependent defects of Neuronal specification and circuit formation in Autism Spectrum Disorders
01/02/2018 → 31/03/2018
Project: Other project
Datasets
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Fragile X urine microRNA profiling
Castrén, M. (Creator) & Laiho, A. (Producer), NCBI GEO, 9 Jan 2020
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE143347
Dataset
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Functional changes of AMPA responses in human induced pluripotent stem cell-derived neural progenitors in fragile X syndrome
Castrén, M. (Creator) & Achuta, V. S. (Contributor), NCBI GEO, 18 Sept 2017
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE103965
Dataset
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Reduced LYNX1 and epilepsy phenotype-related changes in transcriptome of human iPSC-derived neural progenitors modeling fragile X syndrome
Castrén, M. (Owner) & Corcoran, P. (Contributor), NCBI GEO, 2022
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE216875
Dataset
Prizes
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EVO grant for encouragement of scientific studies
Castrén, Maija (Recipient), 1999
Prize: Prizes and awards
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Fogarty fellowship
Castren, Maija (Recipient) & Castrén, Maija (Recipient), 1986
Prize: Prizes and awards
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Max-Planck Scholarship
Castren, Maija (Recipient) & Castrén, Maija (Recipient), 1990
Prize: Prizes and awards
Activities
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Autismitutkimus Suomessa
Maija Castrén (Speaker)
22 Apr 2022Activity: Talk or presentation types › Invited talk
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Contribution of astrocytes to impaired neuronal function in fragile X syndrome
Maija Castrén (Speaker)
14 Jun 2022Activity: Talk or presentation types › Oral presentation
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Human iPSC-derived astrocytes in studies elucidating contribution of astrocytes to impaired neuronal function in neurodevelopmental diseases
Maija Castrén (Speaker)
15 Jun 2022 → 17 Jun 2022Activity: Talk or presentation types › Invited talk
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Childhood-onset genetic white matter disorders of the brain in Northern Finland
Maija Castrén (Pre-examiner)
May 2021Activity: Examination types › Pre-examiner of doctoral thesis
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Generation of the Human Pluripotent Stem-Cell-Derived Astrocyte Model with Forebrain Identity
Maija Castrén (Supervisor)
2021Activity: Examination types › Supervision of other thesis (Master's, Licentiate)
Press/Media
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Kantasolututkimuksesta apua perinnöllisen kehitysvamman ja autismin hoitoon
23/04/2020
1 Media contribution
Press/Media: Press / Media
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Cholesterol-Dependent Changes in Fragile X Astrocytes
01/03/2020
1 Media contribution
Press/Media: Press / Media
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Autismin kirjolla - monimuotoisia häiriöitä, kehityksellisiä ongelmia, mutta myös erityislahjakkuutta
07/05/2019
1 item of Media coverage
Press/Media: Press / Media
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A Study Connects the Genetic Background of ASD with Stem Cell Dysfunction
04/12/2018
1 item of Media coverage
Press/Media: Press / Media
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Altered Progenitor Cell Signaling Linked to Autism
04/12/2018
1 item of Media coverage
Press/Media: Press / Media