Photo of Mark Daly
  • PL 20 (Tukholmankatu 8)

    00014

    Finland

20082019
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Personal profile

Curriculum vitae

Mark Daly, Ph.D. is the Director of the Institute of Molecular Medicine Finland FIMM, where he succeeds Academy Professor Jaakko Kaprio as of February 1, 2018.  Mark was recruited from Harvard Medical School – where he was the founding chief of the Analytic and Translational Unit at the Massachusetts General Hospital from 2011 - and the Broad Institute of MIT and Harvard.

While primarily based in Finland, he retains an active role in Boston at HMS/MGH and as an Institute Member at the Broad Institute, where he is establishing a close partnership between FIMM and the Broad Institute.

Mark’s primary research focus is discovery of genes involved in human disease as a means of providing both insights for therapeutic development as well as improved diagnostics for individual patients.  His lab has developed many foundational computational tools and statistical techniques in genome mapping, linkage and association, and automated interpretation of laboratory data.  The lab has a significant and longstanding commitment in two major medical areas: the inflammatory bowel diseases (Crohn’s and ulcerative colitis) and neuropsychiatric disease (autism and schizophrenia) and Mark has led international consortium efforts large-scale gene mapping efforts in each of these areas – co-chairing the International IBD Genetics Consortium (https://www.ibdgenetics.org), the Psychiatric Genomics Consortium (pgc.unc.edu) and the Autism Sequencing Consortium. With Dr. Palotie, he has helped design and launch the FinnGen Project (www.finngen.fi) as a transformative public-private partnership.  Mark Daly has been an author on more than 450 peer-reviewed manuscripts with a total of more than 200,000 citations, has an h-index of 178, and has been listed by Thompson ISI/Science Watch in 2008 and 2010 as one of the top ten authors ranked by number of high-impact papers.  Mark was the recipient of the Curt Stern Award from the American Society of Human Genetics in 2014 and was elected to the National Academy of Medicine in 2017.

 

Fields of Science

  • 112 Statistics and probability
  • 1184 Genetics, developmental biology, physiology

International and National Collaboration Publications and projects within past five years.

Publications 2008 2019

2018 William Allan Award Introduction: Eric S. Lander

Daly, M. J., 7 Mar 2019, In : American Journal of Human Genetics. 104, 3, p. 373-374 2 p.

Research output: Contribution to journalEditorialScientific

Assessment of genetic variant burden in epilepsy-associated brain lesions

Niestroj, L-M., May, P., Artomov, M., Kobow, K., Coras, R., Perez-Palma, E., Altmueller, J., Thiele, H., Nürnberg, P., Leu, C., Palotie, A., Daly, M. J., Klein, K. M., Beschorner, R., Weber, Y. G., Blümcke, I. & Lal, D., Nov 2019, In : European Journal of Human Genetics. 27, 11, p. 1738-1744 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes

Artomov, M., Joseph, V., Tiao, G., Thomas, T., Schrader, K., Klein, R. J., Kiezun, A., Gupta, N., Margolin, L., Stratigos, A. J., Kim, I., Shannon, K., Ellisen, L. W., Haber, D., Getz, G., Tsao, H., Lipkin, S. M., Altshuler, D., Offit, K. & Daly, M. J., May 2019, In : European Journal of Human Genetics. 27, 5, p. 824-828 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Clinical use of current polygenic risk scores may exacerbate health disparities

Martin, A. R., Kanai, M., Kamatani, Y., Okada, Y., Neale, B. M. & Daly, M. J., Apr 2019, In : Nature Genetics. 51, 4, p. 584-591 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

ADHD Working Grp Psychiat Genomics, Early Lifecourse Genetic & 23andMe Res Team, Jan 2019, In : Nature Genetics. 51, 1, p. 63-+ 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Activities 2018 2018

  • 15 Invited talk
  • 9 Academic visit at UH
  • 1 Organisation and participation in conferences, workshops, courses, seminars

Talk: How can medical and genomics research benefit from AI and data-driven approaches

Mark Daly (Invited speaker)
12 Sep 2018

Activity: Talk or presentation typesInvited talk

Inaugural talk: The Genetics of Common Disease and the future of Individualised Medicine

Mark Daly (Speaker)
3 Oct 2018

Activity: Talk or presentation typesInvited talk

Talk: Beyond GWAS – realizing the promise of human genetics

Mark Daly (Speaker)
7 Jun 2018

Activity: Talk or presentation typesInvited talk

Juha Karjalainen

Mark Daly (Host)
3 Aug 201831 Aug 2018

Activity: Hosting a visitor typesAcademic visit at UH

Javlon Isomurodov

Mark Daly (Host)
1 Nov 201831 Jan 2019

Activity: Hosting a visitor typesAcademic visit at UH