Markku Varjosalo

Publications

Research output per year 2006 2017 2018 2019 2020 2021 2022 2023 2023

• 136 Article
• 6 Review Article
• 2 Doctoral Thesis
• 1 Chapter
• 3 More
  • 1 Abstract
  • 1 Meeting Abstract
  • 1 Letter

Research output per year

Research output per year

Search results

• 2023

  Actin-rich lamellipodia-like protrusions contribute to the integrity of epithelial cell-cell junctions

  Senju, Y., Mushtaq, T., Vihinen, H., Manninen, A., Saarikangas, J., Ven, K., Engel, U., Varjosalo, M., Jokitalo, E. & Lappalainen, P., May 2023, In: Journal of Biological Chemistry. 299, 5, 14 p., 104571.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Biallelic NFATC1 mutations cause an inborn error of immunity with impaired CD8+ T-cell function and perturbed glycolysis

  Kostel Bal, S., Giuliani, S., Block, J., Repiscak, P., Hafemeister, C., Shahin, T., Kasap, N., Ransmayr, B., Miao, Y., van de Wetering, C., Frohne, A., Jimenez-Heredia, R., Schuster, M. K., Zoghi, S., Hertlein, V., Thian, M., Bykov, A., Babayeva, R., Bilgic Eltan, S., Karakoc-Aydiner, E., & 15 othersShaw, L. E., Chowdhury, I., Varjosalo, M., Argüello, R. J., Farlik, M., Ozen, A., Serfling, E. A. E., Dupré, L., Bock, C., Halbritter, F., Hannich, J. T., Castanon, I., Kraakman, M. J., Baris, S. & Boztug, K., 2023, (E-pub ahead of print) In: Blood.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Characterization of Expanded Gamma Delta T Cells from Atypical X-SCID Patient Reveals Preserved Function and IL2RG-Mediated Signaling

  Tuovinen, E. A., Pöysti, S., Hamdan, F., Le, K. M., Keskitalo, S., Turunen, T., Minier, L., Mamia, N., Heiskanen, K., Varjosalo, M., Cerullo, V., Kere, J., Seppänen, M. R. J., Hänninen, A. & Grönholm, J., Feb 2023, In: Journal of Clinical Immunology. 43, 2, p. 358–370 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Comprehensive characterization of the embryonic factor LEUTX

  Gawriyski, L., Jouhilahti, E-M., Yoshihara, M., Fei, L., Weltner, J., Airenne, T., Bhagat, S., Trokovic, R., Tervaniemi, M. H., Murakawa, Y., Salokas, K., Liu, X., Miettinen, S., Bürglin, T. R., Sahu, B., Otonkoski, T., Johnson, M. S., Katayama, S., Varjosalo, M. & Kere, J., 17 Mar 2023, In: iScience. 26, 3, 30 p., 106172.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Decoding Oncofusions: Unveiling Mechanisms, Clinical Impact, and Prospects for Personalized Cancer Therapies

  Salokas, K., Dashi, G. & Varjosalo, M., Jul 2023, In: Cancers. 15, 14, 27 p.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

• Deep Immune Profiling of Multiple Myeloma at Diagnosis and under Lenalidomide Maintenance Therapy

  Luoma, S., Sergeev, P., Javarappa, K. K., Öhman, T. J., Varjosalo, M., Säily, M., Anttila, P., Sankelo, M., Partanen, A., Nihtinen, A., Heckman, C. A. & Silvennoinen, R., 4 May 2023, In: Cancers. 15, 9, 15 p., 2604.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• Long-term follow up of families with pathogenic NFKB1 variants reveals incomplete penetrance and frequent inflammatory sequelae

  Tuovinen, E. A., Kuismin, O., Soikkonen, L., Martelius, T., Kaustio, M., Hämäläinen, S., Viskari, H., Syrjänen, J., Wartiovaara-Kautto, U., Eklund, K. K., Saarela, J., Varjosalo, M., Kere, J., Hautala, T. & Seppänen, M. R. J., Jan 2023, In: Clinical Immunology. 246, 5 p., 109181.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Psychedelics promote plasticity by directly binding to BDNF receptor TrkB

  Moliner, R., Girych, M., Brunello, C. A., Kovaleva, V., Biojone, C., Enkavi, G., Antenucci, L., Kot, E. F., Goncharuk, S. A., Kaurinkoski, K., Kuutti, M., Fred, S. M., Elsilä, L., Sakson, S., Cannarozzo, C., Diniz, C. R. A. F., Seiffert, N., Rubiolo, A., Haapaniemi, H., Meshi, E., & 13 othersNagaeva, E., Öhman, T., Rog, T., Kankuri, E., Vilar, M., Varjosalo, M., Korpi, E. R., Permi, P., Mineev, K. S., Saarma, M., Vattulainen, I., Casarotto, P. C. & Castren, E., Jun 2023, In: Nature Neuroscience. 26, 6, p. 1032–1041 31 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Reduced binding of apoE4 to complement factor H promotes amyloid-beta oligomerization and neuroinflammation

  Chernyaeva, L., Ratti, G., Teirilä, L., Fudo, S., Rankka, U., Pelkonen, A., Korhonen, P., Leskinen, K., Keskitalo, S., Salokas, K., Gkolfinopoulou, C., Crompton, K. E., Javanainen, M., Happonen, L., Varjosalo, M., Malm, T., Leinonen, V., Chroni, A., Saavalainen, P., Meri, S., & 4 othersKajander, T., Wollman, A. J. M., Nissilä, E. & Haapasalo, K., 5 Jul 2023, In: EMBO Reports. 24, 7, 23 p., e56467.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• ROR1-STAT3 signaling contributes to ovarian cancer intra-tumor heterogeneity

  Piki, E., Dini, A., Raivola, J., Salokas, K., Zhang, K., Varjosalo, M., Pellinen, T., Välimäki, K., Veskimäe, K. T., Staff, S., Hautaniemi, S., Murumägi, A. & Ungureanu, D., 3 Jul 2023, In: Cell death discovery . 9, 1, 10 p., 222.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• The Impact of ETV6-NTRK3 Oncogenic Gene Fusions on Molecular and Signaling Pathway Alterations

  Kinnunen, M., Liu, X., Niemelä, E., Öhman, T., Gawriyski, L., Salokas, K., Keskitalo, S. & Varjosalo, M., Sep 2023, In: Cancers. 15, 17, 4246.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access
• 2022

  A multi-omics study to characterize the transdifferentiation of human dermal fibroblasts to osteoblast-like cells

  Pihlström, S., Määttä, K., Öhman, T., Mäkitie, R. E., Aronen, M., Varjosalo, M., Mäkitie, O. & Pekkinen, M., 17 Nov 2022, In: Frontiers in Molecular Biosciences. 9, 27 p., 1032026.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Analysis of human brain tissue derived from DBS surgery

  Kangas, S. M., Teppo, J., Lahtinen, M. J., Suoranta, A., Ghimire, B., Mattila, P., Uusimaa, J., Varjosalo, M., Katisko, J. & Hinttala, R., 13 Apr 2022, In: Translational neurodegeneration. 11, 16 p., 22.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• An extracellular receptor tyrosine kinase motif orchestrating intracellular STAT activation

  Vaparanta, K., Jokilammi, A., Tamirat, M., Merilahti, J. A. M., Salokas, K., Varjosalo, M., Ivaska, J., Johnson, M. S. & Elenius, K., 14 Nov 2022, In: Nature Communications. 13, 1, 19 p., 6953 .

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• CDNF Interacts with ER Chaperones and Requires UPR Sensors to Promote Neuronal Survival

  Eesmaa, A., Yu, L-Y., Göös, H., Danilova, T., Nöges, K., Pakarinen, E., Varjosalo, M., Lindahl, M., Lindholm, P. & Saarma, M., Aug 2022, In: International Journal of Molecular Sciences. 23, 16, 27 p., 9489.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• Common variable immunodeficiency in two kindreds with heterogeneous phenotypes caused by novel heterozygous NFKB1 mutations

  Staels, F., De Keukeleere, K., Kinnunen, M., Keskitalo, S., Lorenzetti, F., Vanmeert, M., Prezzemolo, T., Pasciuto, E., Lescrinier, E., Bossuyt, X., Gerbaux, M., Willemsen, M., Neumann, J., Van Loo, S., Corveleyn, A., Willekens, K., Stalmans, I., Meyts, I., Liston, A., Humblet-Baron, S., & 3 othersSeppänen, M., Varjosalo, M. & Schrijvers, R., 20 Sep 2022, In: Frontiers in Immunology. 13, 17 p., 973543.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Defining Optimal Conditions for Tumor Extracellular Vesicle DNA Extraction for Mutation Profiling

  Elzanowska, J., Berrocal, L., García-Peláez, B., Vives-Usano, M., Passos Sebo, B., Maia, J., Batista, S., Teppo, J., Varjosalo, M., Strano Moraes, M. C., Molina-Vila, M. Á. & Costa-Silva, B., 2 Jul 2022, In: Cancers. 14, 13, 18 p., 3258.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• Detrimental NFKB1 missense variants affecting the Rel-homology domain of p105/p50

  Fliegauf, M., Kinnunen, M., Posadas-Cantera, S., Camacho-Ordonez, N., Abolhassani, H., Alsina, L., Atschekzei, F., Bogaert, D. J., Burns, S. O., Church, J. A., Dueckers, G., Freeman, A. F., Hammarström, L., Hanitsch, L. G., Kerre, T., Kobbe, R., Sharapova, S. O., Siepermann, K., Speckmann, C., Steiner, S., & 7 othersVerma, N., Walter, J. E., Westermann-Clark, E., Goldacker, S., Warnatz, K., Varjosalo, M. & Grimbacher, B., 29 Aug 2022, In: Frontiers in Immunology. 13, 18 p., 965326.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• DUX4 is a multifunctional factor priming human embryonic genome activation

  Vuoristo, S., Bhagat, S., Hyden-Granskog, C., Yoshihara, M., Gawriyski, L., Jouhilahti, E-M., Ranga, V., Tamirat, M., Huhtala, M., Kirjanov, I., Nykänen, S., Krjutskov, K., Damdimopoulos, A., Weltner, J., Hashimoto, K., Recher, G., Ezer, S., Paluoja, P., Paloviita, P., Takegami, Y., & 13 othersKanemaru, A., Lundin, K., Airenne, T. T., Otonkoski, T., Tapanainen, J. S., Kawaji, H., Murakawa, Y., Burglin, T. R., Varjosalo, M., Johnson, M. S., Tuuri, T., Katayama, S. & Kere, J., 15 Apr 2022, In: iScience. 25, 4, 29 p., 104137.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Geneettiset ja biologiset analyysit yhdestä solusta

  Keskitalo, S., Auvinen, P. & Varjosalo, M., 2022, In: Duodecim. 138, 15, p. 1291-1297 7 p.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

  File

• Heterozygous premature termination in zinc-finger domain of Kruppel-like factor 2 gene associates with dysregulated immunity

  Pernaa, N., Keskitalo, S., Chowdhury, I., Nissinen, A., Glumoff, V., Keski-Filppula, R., Junttila, J., Eklund, K. K., Santaniemi, W., Siitonen, S., Seppänen, M. R. J., Vähäsalo, P., Varjosalo, M., Åström, P. & Hautala, T., 18 Nov 2022, In: Frontiers in Immunology. 13, 20 p., 819929.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Human pluripotent stem cell-derived cells endogenously expressing follicle-stimulating hormone receptors: modeling the function of an inactivating receptor mutation

  Lundin, K., Sepponen, K., Väyrynen, P., Liu, X., Yohannes, D. A., Survila, M., Ghimire, B., Känsäkoski, J., Katayama, S., Partanen, J., Vuoristo, S., Paloviita, P., Rahman, N., Raivio, T., Luiro, K., Huhtaniemi, I., Varjosalo, M., Tuuri, T. & Tapanainen, J. S., 29 Apr 2022, In: Molecular Human Reproduction. 28, 5, 13 p., 012.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Human transcription factor protein interaction networks

  Göös, H., Kinnunen, M., Salokas, K., Tan, Z., Liu, X., Yadav, L., Zhang, Q., Wei, G-H. & Varjosalo, M., 9 Feb 2022, In: Nature Communications. 13, 1, 16 p., 766.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Identification of germline monoallelic mutations in IKZF2 in patients with immune dysregulation

  Shahin, T., Mayr, D., Shoeb, M. R., Kuehn, H. S., Hoeger, B., Giuliani, S., Gawriyski, L. M., Petronczki, Ö. Y., Hadjadj, J., Bal, S. K., Zoghi, S., Haimel, M., Heredia, R. J., Boutboul, D., Triebwasser, M. P., Rialland-Battisti, F., Chalumeau, N. C., Quartier, P., Tangye, S. G., Fleisher, T. A., & 9 othersRezaei, N., Romberg, N., Latour, S., Varjosalo, M., Halbritter, F., Rieux-Laucat, F., Castanon, I., Rosenzweig, S. D. & Boztug, K., 12 Apr 2022, In: Blood advances. 6, 7, p. 2444-2451 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Multiomics characterization implicates PTK7 in ovarian cancer EMT and cell plasticity and offers strategies for therapeutic intervention

  Raivola, J., Dini, A., Karvonen, H., Piki, E., Salokas, K., Niininen, W., Kaleva, L., Zhang, K., Arjama, M., Gudoityte, G., Seashore-Ludlow, B., Varjosalo, M., Kallioniemi, O., Hautaniemi, S., Murumagi, A. & Ungureanu, D., 17 Aug 2022, In: Cell Death and Disease. 13, 8, 12 p., 714.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• New insights into the molecular mechanisms of ROR1, ROR2, and PTK7 signaling from the proteomics and pharmacological modulation of ROR1 interactome

  Raivola, J., Dini, A., Salokas, K., Karvonen, H., Niininen, W., Piki, E., Varjosalo, M. & Ungureanu, D., May 2022, In: Cellular and Molecular Life Sciences. 79, 5, 16 p., 276.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Parvovirus nonstructural protein 2 interacts with chromatin-regulating cellular proteins

  Mattola, S., Salokas, K., Aho, V., Mäntylä, E., Salminen, S., Hakanen, S., Niskanen, E. A., Salokas, J., Ihalainen, T. O., Airenne, K. J., Kaikkonen-Määttä, M., Parrish, C. R., Varjosalo, M. & Vihinen-Ranta, M., 8 Apr 2022, In: PLoS Pathogens. 18, 4, 32 p., e1010353.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Physical and functional interactome atlas of human receptor tyrosine kinases

  Salokas, K., Liu, X., Öhman, T., Chowdhury, I., Gawriyski, L., Keskitalo, S. & Varjosalo, M., 7 Jun 2022, In: EMBO Reports. 23, 6, 28 p., 54041.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• SARS-CoV-2 Production, Purification Methods and UV Inactivation for Proteomics and Structural Studies

  Plavec, Z., Domanska, A., Liu, X., Laine, P., Paulin, L., Varjosalo, M., Auvinen, P., Wolf, S. G., Anastasina, M. & Butcher, S. J., Sep 2022, In: Viruses-Basel. 14, 9, 12 p., 1989.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• Transient DUX4 expression in human embryonic stem cells induces blastomere-like expression program that is marked by SLC34A2

  Yoshihara, M., Kirjanov, I., Nykänen, S., Sokka, J., Weltner, J., Lundin, K., Gawriyski, L., Jouhilahti, E-M., Varjosalo, M., Tervaniemi, M. H., Otonkoski, T., Trokovic, R., Katayama, S., Vuoristo, S. & Kere, J., 12 Jul 2022, In: Stem cell reports. 17, 7, p. 1743-1756 14 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Vitreal protein myogenic factor 6 is increased in eyes with rhegmatogenous retinal detachment

  Loukovaara, S., Korhonen, A., Varjosalo, M. & Gucciardo, E., Dec 2022, In: Acta Ophthalmologica. 100, 8, p. E1767-E1768 2 p.

  Research output: Contribution to journal › Letter › Scientific
• 2021

  Abstract PO050: EphA2 signaling segregation and modulation by diverse tumor microenvironment components differentially regulates cancer cell invasion and survival

  Moyano-Galceran, L., Turunen, P. S., Sugiyama, N., von Nandelstadh, P., Gucciardo, E., Varjosalo, M. & Lehti, K., 1 Mar 2021.

  Research output: Conference materials › Abstract › peer-review

• A Family With A20 Haploinsufficiency Presenting With Novel Clinical Manifestations and Challenges for Treatment

  Hautala, T., Vähäsalo, P., Kuismin, O., Keskitalo, S., Rajamäki, K., Väänänen, A., Simojoki, M., Säily, M., Pelkonen, I., Tokola, H., Mäkinen, M., Kaarteenaho, R., Jartti, A., Hautala, N., Kantola, S., Jackson, P., Glumoff, V., Saarela, J., Varjosalo, M., Eklund, K. K., & 1 othersSeppänen, M., Dec 2021, In: Journal of Clinical Rheumatology. 27, 8, p. E583-E587 5 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility

  Manjur, A. B. M. K., Lempiainen, J. K., Malinen, M., Varjosalo, M., Palvimo, J. J. & Niskanen, E. A., Jun 2021, In: Journal of Steroid Biochemistry and Molecular Biology. 210, 12 p., 105873.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Commander Complex-A Multifaceted Operator in Intracellular Signaling and Cargo

  Laulumaa, S. & Varjosalo, M., Dec 2021, In: Cells. 10, 12, 12 p., 3447.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• GATA-targeted compounds modulate cardiac subtype cell differentiation in dual reporter stem cell line

  Välimäki, M. J., Leigh, R. S., Kinnunen, S. M., March, A. R., de Sande, A. H., Kinnunen, M., Varjosalo, M., Heinäniemi, M., Kaynak, B. L. & Ruskoaho, H., 18 Mar 2021, In: Stem Cell Research & Therapy. 12, 1, 18 p., 190.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Germline biallelic mutation affecting the transcription factor Helios causes pleiotropic defects of immunity

  Shahin, T., Kuehn, H. S., Shoeb, M. R., Gawriyski, L., Giuliani, S., Repiscak, P., Hoeger, B., Petronczki, O. Y., Bal, S. K., Zoghi, S., Dmytrus, J., Seruggia, D., Castanon, I., Rezaei, N., Varjosalo, M., Halbritter, F., Rosenzweig, S. D. & Boztug, K., Nov 2021, In: Science immunology. 6, 65, 16 p., 3981.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• IRF2BP2 Mutation Is Associated with Increased STAT1 and STAT5 Activation in Two Family Members with Inflammatory Conditions and Lymphopenia

  Palmroth, M., Viskari, H., Seppänen, M. R. J., Keskitalo, S., Virtanen, A., Varjosalo, M., Silvennoinen, O. & Isomäki, P., Aug 2021, In: Pharmaceuticals. 14, 8, 14 p., 797.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells

  Hetemäki, I., Kaustio, M., Kinnunen, M., Heikkilä, N., Keskitalo, S., Nowlan, K., Miettinen, S., Sarkkinen, J., Glumoff, V., Andersson, N., Kettunen, K., Vanhanen, R., Nurmi, K., Eklund, K. K., Dunkel, J., Mäyränpää, M. I., Schlums, H., Arstila, T. P., Kisand, K., Bryceson, Y., & 6 othersPeterson, P., Otava, U., Syrjänen, J., Saarela, J., Varjosalo, M. & Kekäläinen, E., 26 Nov 2021, In: Science immunology. 6, 65, eabe3454.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Molecular pathogenesis of rhegmatogenous retinal detachment

  Öhman, T., Gawriyski, L., Miettinen, S., Varjosalo, M. & Loukovaara, S., 13 Jan 2021, In: Scientific Reports. 11, 1, 15 p., 966.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Rapid genome editing by CRISPR-Cas9-POLD3 fusion

  Reint, G., Li, Z., Labun, K., Keskitalo, S., Soppa, I., Mamia, K., Tolo, E., Szymanska, M., Meza-Zepeda, L. A., Lorenz, S., Cieslar-Pobuda, A., Hu, X., Bordin, D. L., Staerk, J., Valen, E., Schmierer, B., Varjosalo, M., Taipale, J. & Haapaniemi, E., 13 Dec 2021, In: eLife. 10, 28 p., 75415.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• RTN4B interacting protein FAM134C promotes ER membrane curvature and has a functional role in autophagy

  Kumar, D., Lak, B., Suntio, T., Vihinen, H., Belevich, I., Viita, T., Xiaonan, L., Vartiainen, A., Vartiainen, M., Varjosalo, M. & Jokitalo, E., 1 Jun 2021, In: Molecular Biology of the Cell. 32, 12, p. 1158-1170 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• SARS-CoV-2-host proteome interactions for antiviral drug discovery

  Liu, X., Huuskonen, S., Laitinen, T., Redchuk, T., Bogacheva, M., Salokas, K., Pohner, I., Öhman, T., Tonduru, A. K., Hassinen, A., Gawriyski, L., Keskitalo, S., Vartiainen, M. K., Pietiainen, V., Poso, A. & Varjosalo, M., Nov 2021, In: Molecular Systems Biology. 17, 11, 26 p., 10396.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Skeletal muscle proteomes reveal downregulation of mitochondrial proteins in transition from prediabetes into type 2 diabetes

  Öhman, T., Teppo, J., Datta, N., Mäkinen, S., Varjosalo, M. & Koistinen, H. A., 23 Jul 2021, In: iScience. 24, 7, 22 p., 102712.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites

  Paakinaho, V., Lempiäinen, J. K., Sigismondo, G., Niskanen, E. A., Malinen, M., Jääskeläinen, T., Varjosalo, M., Krijgsveld, J. & Palvimo, J. J., 26 Feb 2021, In: Nucleic Acids Research. 49, 4, p. 1951-1971 21 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• The comprehensive interactomes of human adenosine RNA methyltransferases and demethylases reveal distinct functional and regulatory features

  Covelo-Molares, H., Obrdlik, A., Postulkova, I., Dohnalkova, M., Gregorova, P., Ganji, R., Potesil, D., Gawriyski, L., Varjosalo, M. & Vanacova, S., 8 Nov 2021, In: Nucleic Acids Research. 49, 19, p. 10895-10910 16 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor

  Eesmaa, A., Yu, L-Y., Göös, H., Nõges, K., Kovaleva, V., Hellman, M., Zimmermann, R., Jung, M., Permi, P., Varjosalo, M., Lindholm, P. & Saarma, M., 2021, In: Journal of Biological Chemistry. 296, 23 p., 100295.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2020

  A second hybrid-binding domain modulates the activity of Drosophila ribonuclease H1

  Gonzalez de Cozar, J. M., Carretero-Junquera, M., Ciesielski, G. L., Miettinen, S. M., Varjosalo, M., Kaguni, L. S., Dufour, E. & Jacobs, H. T., Nov 2020, In: Journal of Biochemistry. 168, 5, p. 515-533 19 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Association of host protein VARICOSE with HCPro within a multiprotein complex is crucial for RNA silencing suppression, translation, encapsidation and systemic spread of potato virus A infection

  Swarnalok, D., Pollari, M., Varjosalo, M. & Mäkinen, K., Oct 2020, In: PLoS Pathogens. 16, 10, 32 p., 1008956.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Behcet disease (BD) and BD-like clinical phenotypes: NF-kappa B pathway in mucosal ulcerating diseases

  Perazzio, S. F., Allenspach, E. J., Eklund, K. K., Varjosalo, M., Shinohara, M. M., Torgerson, T. R. & Seppänen, M. R. J., Nov 2020, In: Scandinavian Journal of Immunology. 92, 5, 14 p., 12973.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

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