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Mart Saarma

  • PL 56 (Viikinkaari 5)

    00014

    Finland

  • Viikinkaari 5, Biocenter 2

    00790 Helsinki

    Finland

1991 …2040
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Publications 1991 2019

1991

DEPENDENCE OF KIDNEY MORPHOGENESIS ON THE EXPRESSION OF NERVE GROWTH-FACTOR RECEPTOR

SARIOLA, H., SAARMA, M., SAINIO, K., ARUMAE, U., PALGI, J., VAAHTOKARI, A., THESLEFF, I. & KARAVANOV, A., 1991, In : Science Progress. 254, p. 571-573 3 p.

Research output: Contribution to journalArticleScientificpeer-review

1993

NEUROTROPHIN RECEPTORS IN KIDNEY DEVELOPMENT

SAARMA, M., SAINIO, K., MOSHNYAKOV, M., SAXEN, L. & SARIOLA, H., 1993, In : Journal of Neurochemistry. 61, p. S179-S179 1 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

NEUROTROPHINS AND THEIR RECEPTORS IN RAT PERIPHERAL TRIGEMINAL SYSTEM DURING MAXILLARY NERVE GROWTH

ARUMAE, U., PIRVOLA, U., PALGI, J., KIEMA, T. R., PALM, K., MOSHNYAKOV, M., YLIKOSKI, J. & SAARMA, M., 1993, In : European Journal of Cell Biology. 122, p. 1053-1065 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Potato biotechnology in Finland

Valkonen, J., Saarma, M., Pulli, S. & Pehu, E., 1993, Symposium on Updates in Food Biotechnology. Helsinki, Finland. March 15-16. p. 4

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientific

TRANSGENIC POTATO PLANTS EXPRESSING MAMMALIAN 2'-5' OLIGOADENYLATE SYNTHETASE ARE PROTECTED FROM POTATO VIRUS-X INFECTION UNDER FIELD CONDITIONS

TRUVE, E., AASPÕLLU, A., HONKANEN, J., PUSKA, R., MEHTO, M., HASSI, A., Teeri, T. H., KELVE, M., SEPPÄNEN, P. & SAARMA, M., 1993, In : Bio/technology. 11, 9, p. 1048-1052 5 p.

Research output: Contribution to journalArticleScientificpeer-review

1994

ANTISENSE INHIBITION OF LOW-AFFINITY NERVE GROWTH-FACTOR RECEPTOR IN KIDNEY CULTURES - POWER AND PITFALLS

SAINIO, K., SAARMA, M., NONCLERCQ, D., PAULIN, L. & SARIOLA, H., 1994, In : Cellular and Molecular Neurobiology. 14, p. 439-457 19 p.

Research output: Contribution to journalArticleScientificpeer-review

COORDINATED EXPRESSION AND FUNCTION OF NEUROTROPHINS AND THEIR RECEPTORS IN THE RAT INNER-EAR DURING TARGET INNERVATION

PIRVOLA, U., ARUMAE, U., MOSHNYAKOV, M., PALGI, J., SAARMA, M. & YLIKOSKI, J., 1994, In : Hearing Research. 75, p. 131-144 14 p.

Research output: Contribution to journalArticleScientificpeer-review

NEURONAL CHARACTERISTICS IN EMBRYONIC RENAL STROMA

SAINIO, K., NONCLERCQ, D., SAARMA, M., PALGI, J., SAXEN, L. & SARIOLA, H., 1994, In : International journal of plant developmental biology. 38, p. 77-84 8 p.

Research output: Contribution to journalArticleScientificpeer-review

NEUROTROPHINS AND CILIARY NEUROTROPHIC FACTOR - THEIR BIOLOGY AND PATHOLOGY

SARIOLA, H., SAINIO, K., ARUMAE, U. & SAARMA, M., 1994, In : Annals of Internal Medicine. 26, p. 355-363 9 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

1995

3 STRAIN GROUPS OF POTATO-A-POTYVIRUS BASED ON HYPERSENSITIVE RESPONSES IN POTATO, SEROLOGICAL PROPERTIES, AND COAT PROTEIN SEQUENCES

VALKONEN, J. P. T., PUURAND, U., SLACK, S. A., MAKINEN, K. & SAARMA, M., 1995, In : Plant Disease. 79, p. 748-753 6 p.

Research output: Contribution to journalArticleScientificpeer-review

CHARACTERIZATION OF THE RAT LIGHT NEUROFILAMENT (NF-L) GENE PROMOTER AND IDENTIFICATION OF NGF AND CAMP-RESPONSIVE REGIONS

REEBEN, M., NEUMAN, T., PALGI, J., PALM, K., PAALME, V. & SAARMA, M., 1995, In : Journal of Neuroscience Research. 40, 2, p. 177-188 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Infectious in vitro transcripts from cloned cDNA of the potato A potyvirus

Puurand, U., Valkonen, J. P. T., Makinen, K., Rabenstein, F. & Saarma, M., 1996, In : Virus Research. 40, p. 135-140 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Localization of glial cell line-derived neurotrophic factor (GDNF) mRNA in embryonic rat by in situ hybridization

Sainio, K., Suvanto, P., Hiltunen, J. O., Arumae, U., Moshnyakov, M., Sariola, H., Sainio, K. & Saarma, M., 1996, In : European Journal of Neuroscience. 8, p. 816-822 7 p.

Research output: Contribution to journalArticleScientificpeer-review

The rho(1) GABA receptor cloned from rat retina is down-modulated by protons

Wegelius, K., Reeben, M., Rivera, C., Kaila, K., Saarma, M. & Pasternack, M., 1996, In : NeuroReport. 7, p. 2005-2009 5 p.

Research output: Contribution to journalArticleScientificpeer-review

1997

Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium

Sainio, K., Suvanto, P., Davies, J., Wartiovaara, J., Wartiovaara, K., Saarma, M., Arumae, U., Meng, X. J., Lindahl, M., Pachnis, V. & Sariola, H., 1997, In : Development. 124, p. 4077-4087 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Localization of nerve cells in the developing rat tooth

Luukko, K., Sainio, K., Sariola, H., Saarma, M. & Thesleff, I., 1997, In : Indian Journal of Dental Research. 76, p. 1350-1356 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Monoclonal antibodies specific for Semliki Forest virus replicase protein nsP2

Kujala, P., Rikkonen, M., Ahola, T., Kelve, M., Saarma, M. & Kaariainen, L., Feb 1997, In : Journal of General Virology. 78, p. 343-351 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Neurotrophin mRNA expression in the developing tooth suggests multiple roles in innervation and organogenesis

Luukko, K., Arumae, U., Karavanov, A., Moshnyakov, M., Sainio, K., Sariola, M., Saarma, M. & Thesleff, I., 1997, In : Developmental Dynamics. 210, p. 117-129 13 p.

Research output: Contribution to journalArticleScientificpeer-review

1998

Distribution of GABA receptor rho subunit transcripts in the rat brain

Wegelius, K., Pasternack, M., Hiltunen, J. O., Rivera, C., Kaila, K., Saarma, M. & Reeben, M., 1998, In : European Journal of Neuroscience. 10, p. 350-357 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Gene expression and cell death in ozone-exposed plants: Is programmed cell death involved in ozone damage in ozone-sensitive Arabidopsis mutants?

Overmyer, K., Kangasjärvi, J., Kuittinen, T. P. & Saarma, M., 1998, Responses of Plant Metabolism to Air Pollution and Global Change. The Hague: SPB Academic Publishing, p. 403-406 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

The messenger RNAs for both glial cell line-derived neurotrophic factor receptors, c-ret and GDNFR alpha, are induced in the rat brain in response to kainate-induced excitation

Reeben, M., Laurikainen, A., Hiltunen, J. O., Castren, E. & Saarma, M., 1998, In : Neuroscience. 83, p. 151-159 9 p.

Research output: Contribution to journalArticleScientificpeer-review

1999

Developmental expression of palmitoyl protein thioesterase in normal mice

Isosomppi, J., Heinonen, O., Hiltunen, J. O., Greene, N. D. E., Vesa, J., Uusitalo, A., Mitchison, H. M., Saarma, M., Jalanko, A. & Peltonen, L., 1999, In : Developmental Brain Research. 118, p. 111 11 p.

Research output: Contribution to journalArticleScientificpeer-review

GDNF family ligands and receptors are differentially regulated after brain insults in the rat

Kokaia, Z., Airaksinen, M. S., Nanobashvili, A., Larsson, E., Kujamaki, E., Lindvall, O. & Saarma, M., 1999, In : European Journal of Neuroscience. 11, p. 1202-1216 15 p.

Research output: Contribution to journalArticleScientificpeer-review

GDNF family neurotrophic factor signaling: Four masters, one servant?

Airaksinen, M. S., Titievsky, A. & Saarma, M., 1999, In : Molecular and Cellular Neuroscience. 13, p. 313-325 13 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Retarded growth and deficits in the enteric and parasympathetic nervous system in mice lacking GFR alpha 2, a functional neurturin receptor

Rossi, J., Luukko, K., Poteryaev, D., Laurikainen, A., Sun, Y. F., Laakso, T., Eerikainen, S., Tuominen, R., Lakso, M., Rauvala, H., Arumae, U., Pasternack, M., Saarma, M. & Airaksinen, M. S., 1999, In : Neuron. 22, 2, p. 243-252 10 p.

Research output: Contribution to journalArticleScientificpeer-review

The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation

Rivera, C., Voipio, J., Payne, J. A., Ruusuvuori, E., Lahtinen, H., Lamsa, K., Pirvola, U., Saarma, M. & Kaila, K., 1999, In : Nature. 397, p. 251-255 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Toward understanding the neuronal pathogenesis of aspartylglucosaminuria: Expression of aspartylglucosaminidase in brain during development

Uusitalo, A., Tenhunen, K., Kopra, O., Hiltunen, J. O., Saarma, M., Haltia, M., Jalanko, A. & Peltonen, L., 1999, In : Molecular Genetics and Metabolism. 67, 4, p. 294-307 14 p.

Research output: Contribution to journalArticleScientificpeer-review

2000

A novel human processed gene, DAD-R, maps to 12p12 and is expressed in several organs

Kuittinen, T. P., Eggert, A., Lindholm, P. K., Horelli-Kuitunen, N., Palotie, A., Maris, J. M. & Saarma, M., 2000, In : FEBS Letters. 2000, 473, p. 233-236

Research output: Contribution to journalArticleScientificpeer-review

Development and persistence of kindling epilepsy are impaired in mice lacking glial cell line-derived neurotrophic factor family receptor alpha 2

Nanobashvili, A., Airaksinen, M. S., Kokaia, M., Rossi, J., Asztely, F., Olofsdotter, K., Mohapel, P., Saarma, M., Lindvall, O. & Kokaia, Z., 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, p. 12312-12317 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Distinct roles for GFR alpha 1 and GFR alpha 2 signalling in different cranial parasympathetic ganglia in vivo

Rossi, J., Tomac, A., Saarma, M. & Airaksinen, M. S., 2000, In : European Journal of Neuroscience. 12, p. 3944-3952 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Expression and alternative splicing of mouse GFRA4 suggests roles in endocrine cell development

Airaksinen, M. S., Lindahl, M., Timmusk, T., Rossi, J. & Saarma, M., 2000, In : Molecular and Cellular Neuroscience. 12, p. 328-328 1 p.

Research output: Contribution to journalArticleScientificpeer-review

GDNF family receptors in the embryonic and postnatal rat heart and reduced cholinergic innervation in mice hearts lacking Ret or GFR alpha 2

Hiltunen, J. O., Laurikainen, A., Airaksinen, M. S. & Saarma, M., 2000, In : Developmental Dynamics. 219, p. 28-39 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Regulation of cell fate decision of undifferentiated spermatogonia by GDNF

Meng, X. J., Lindahl, M., Hyvönen, M. E., Parvinen, M., de Rooij, D. G., Hess, M. W., Raatikainen-Ahokas, A., Sainio, K., Rauvala, H., Lakso, M., Pichel, J. G., Westphal, H., Saarma, M. & Sariola, H., 2000, In : Science. 287, p. 1489-1493 5 p.

Research output: Contribution to journalArticleScientificpeer-review

2001

Human glial cell line-derived neurotrophic factor receptor alpha 4 is the receptor for persephin and is predominantly expressed in normal and malignant thyroid medullary cells

Lindahl, M., Poteryaev, D., Yu, L. Y., Arumae, U., Timmusk, T., Bongarzone, I., Aiello, A., Pierotti, M. A., Airaksinen, M. S. & Saarma, M., 2001, In : Journal of Biological Chemistry. 276, p. 9344-9351 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Identification of the genome-linked protein in virions of Potato virus A, with comparison to other members in genus Potyvirus

Oruetxebarria, I., Guo, D. Y., Merits, A., Makinen, K., Saarma, M. & Valkonen, J. P. T., 2001, In : Virus Research. 73, p. 103-112 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Phosphorylation down-regulates the RNA binding function of the coat protein of potato virus A

Translated title of the contribution: Phosphorylation down-regulates the RNA binding function of the coat protein of potato virus AIvanov, K. I., Puustinen, P., Merits, A., Saarma, M. & Mäkinen, K., 1 Apr 2001, In : Journal of Biological Chemistry. 276, 17, p. 13530-13540 11 p.

Research output: Contribution to journalArticleScientificpeer-review

2002

BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion

Rivera, C., Li, H., Thomas-Crusells, J., Lahtinen, H., Viitanen, T., Nanobashvili, A., Kokaia, Z., Airaksinen, M. S., Voipio, J., Kaila, K. & Saarma, M., 2002, In : Journal of Cell Biology. 159, p. 747-752 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Proteolytic processing of potyviral proteins and polyprotein processing intermediates in insect and plant cells

Merits, A., Rajamaki, M. L., Lindholm, P., Runeberg-Roos, P., Kekarainen, T., Puustinen, P., Makelainen, K., Valkonen, J. P. T. & Saarma, M., 2002, In : Journal of General Virology. 83, p. 1211-1221 11 p.

Research output: Contribution to journalArticleScientificpeer-review

The GDNF family: Signalling, biological functions and therapeutic value

Airaksinen, M. S. & Saarma, M., 2002, In : Nature Reviews. Neuroscience. 3, p. 383-394 12 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

2003

A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system

Lauren, J., Airaksinen, M. S., Saarma, M. & Timmusk, T., 2003, In : Genomics. 81, p. 411-421 11 p.

Research output: Contribution to journalArticleScientificpeer-review

DeltaFosB expression is enhanced in heterozygous GDNF knockout mice after repeated morphine treatment

Airavaara, M., Gaddnas, HG., Piepponen, TP., Airaksinen, MS., Saarma, M. & Ahtee, L., Sep 2003, In : Behavioural Pharmacology. 14, p. S50-S50 1 p.

Research output: Contribution to journalConference articleScientific

Developmental up-regulation of KCC2 in the absence of GABAergic and glutamatergic transmission

Ludwig, A., Li, H., Saarma, M., Kaila, K. & Rivera, C., 2003, In : European Journal of Neuroscience. 18, p. 3199-3206 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Effects of acute morphine on metabolism of dopamine in dorsal striatum of heterozygous GDNF knockout mice

Mijatovic, J., Airavaara, M., Piepponen, TP., Saarma, M. & Ahtee, L., Jun 2003, In : European Journal of Pharmaceutical Sciences. 19, p. S26-S26 1 p.

Research output: Contribution to journalConference articleScientific

GDNF-deprived sympathetic neurons die via a novel nonmitochondrial pathway

Yu, L. Y., Jokitalo, E., Sun, Y. F., Mehlen, P., Lindholm, D., Saarma, M. & Arumae, U., 2003, In : Journal of Cell Biology. 163, p. 987-997 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Two novel mammalian Nogo receptor homologs differentially expressed in the central and peripheral nervous systems

Lauren, J., Airaksinen, M. S., Saarma, M. & Timmusk, T., 2003, In : Molecular and Cellular Neuroscience. 24, p. 581-594 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Two potato proteins, including a novel RING finger protein (HIP1), interact with the potyviral multifunctional protein HCpro

Guo, D. Y., Spetz, C., Saarma, M. & Valkonen, J. P. T., 2003, In : Molecular Plant - Microbe Interactions. 16, 5, p. 405-410 6 p.

Research output: Contribution to journalArticleScientificpeer-review