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Mart Saarma

  • PL 56 (Viikinkaari 5)

    00014

    Finland

  • Viikinkaari 5, Biocenter 2

    00790 Helsinki

    Finland

1991 …2040
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Publications 1991 2019

Chapter

Information processing by NGF-activated signaling networks

Paveliev, M. & Saarma, M., 2008, Nerve Growth Factor: New Research. McIntire, G. K. (ed.). New York: Nova Science Publishers, p. 345-358

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Neurotrophic Factors

Saarma, M., Lindholm, P. K. & Arumäe, U., 2012, Movement Disorders. Watts, R. L., Standaert, D. G. & Obeso, J. A. (eds.). 3rd Edition ed. McGraw-Hill Companies, Inc. , p. 129-140 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Conference article

CDNF is a novel neurotrophic factor for doparninergic neurons in vivo

Voutilainen, M. H., Lindholm, P., Saarma, M. & Tuominen, R. K., 9 Jun 2008, In : European Journal of Pharmaceutical Sciences. 34, 1, p. S9-S9 1 p.

Research output: Contribution to journalConference articleScientificpeer-review

Comparison of striatal and nigral administration of CDNF in 6-OHDA rat model of PD

Voutilainen, M. H., Panhelainen, A., Albert, K., Tuominen, R. K., Airavaara, M. & Saarma, M., May 2014, In : Movement Disorders. 29, p. S331-S331 1 p.

Research output: Contribution to journalConference articleScientific

DeltaFosB expression is enhanced in heterozygous GDNF knockout mice after repeated morphine treatment

Airavaara, M., Gaddnas, HG., Piepponen, TP., Airaksinen, MS., Saarma, M. & Ahtee, L., Sep 2003, In : Behavioural Pharmacology. 14, p. S50-S50 1 p.

Research output: Contribution to journalConference articleScientific

Drosophila gene encoding a homolog of the novel human neurotrophic factor MANF

Palgi, M., Lindstrom, R., Peranen, J., Piepponen, P., Saarma, M. & Heino, T. I., 2006, In : Journal of Neurogenetics. 20, p. 196-197 2 p.

Research output: Contribution to journalConference articleScientific

Effects of acute morphine on metabolism of dopamine in dorsal striatum of heterozygous GDNF knockout mice

Mijatovic, J., Airavaara, M., Piepponen, TP., Saarma, M. & Ahtee, L., Jun 2003, In : European Journal of Pharmaceutical Sciences. 19, p. S26-S26 1 p.

Research output: Contribution to journalConference articleScientific

Effects of repeatedly administered morphine on locomotor activity, conditioned place preference and extracellular dopamine in GDNF +/- knockout mice

Airavaara, M., Tuomainen, H., Piepponen, T. P., Saarma, M. & Ahtee, L., Jul 2006, In : Acta Pharmacologica Sinica. 27, p. 419-419 1 p.

Research output: Contribution to journalConference articleScientific

Imaging serotonin and dopamine transporters with dynamic 123I-beta-CIT SPECT in mouse brain

Pitkonen, M., Hippeläinen, E. T., Raki, M., Savolainen, S., Andressoo, J., Saarma, M. & Bergstrom, K., Oct 2013, In : European Journal of Nuclear Medicine and Molecular Imaging. 40, p. S413-S414 2 p.

Research output: Contribution to journalConference articleScientific

Morphine-induced conditioned place preference in heterozygous GDNF knockout mice

Airavaara, MA., Piepponen, TP., Saarma, M. & Ahtee, L., Sep 2005, In : Behavioural Pharmacology. 16, p. S75-S75 1 p.

Research output: Contribution to journalConference articleScientific

New Mouse Models for Studying Postnatal Role of GDNF In Vivo

Andressoo, J. -O., Mijatovic, J., Kuman, A., Amberg, C., Grealish, S., Lindahl, M., Bjorklund, A., Lindholm, J., Casten, E., Kulesskaya, N., Rauvala, H., Piepponen, P. & Saarma, M., 2010, In : Cell Transplantation. 19, p. 331-331 1 p.

Research output: Contribution to journalConference articleScientific

Novel Neurotrophic Factor CDNF: Biology and Therapeutic Potential

Saarma, M., Lindholm, P., Andressoo, J. -O., Perlinen, J. & Lindahl, M., 2010, In : Cell Transplantation. 19, 3, p. 359-360 2 p.

Research output: Contribution to journalConference articleScientific

Rescue and gene silencing experiments to dissect the DmMANF mutant lethality

Lindstrom, R., Palgi, M., Saarma, M. & Heino, T. I., 2009, In : Journal of Neurogenetics. 23, p. S8-S8 1 p.

Research output: Contribution to journalConference articleScientific

Study of DmMANF, the Evolutionarily Conserved Drosophila Neurotrophic Factor

Palgi, M., Lindstrom, R., Stratoulias, V., Saarma, M. & Heino, T. I., Dec 2010, In : Journal of Neurogenetics. 24, p. 84-84 1 p.

Research output: Contribution to journalConference articleScientific

The neuronal ceroid lipofuscinosis Cln8 gene expression in mouse during development and in the hippocampal kindling model of epilepsy

Lonka, L. I., Aalto, A., Kopra, O., Kuronen, M., Ranta, S., Kokaia, Z., Saarma, M. & Lehesjoki, A., 2004, In : Molecular Biology of the Cell. 15, p. 207A-207A 1 p.

Research output: Contribution to journalConference articleScientific

Conference contribution

Potato biotechnology in Finland

Valkonen, J., Saarma, M., Pulli, S. & Pehu, E., 1993, Symposium on Updates in Food Biotechnology. Helsinki, Finland. March 15-16. p. 4

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientific

Editorial

Obesity: Receptors identified for a weight regulator

Saarma, M. & Goldman, A., 12 Oct 2017, In : Nature. 550, 7675, p. 195-197 3 p.

Research output: Contribution to journalEditorialScientificpeer-review

Meeting Abstract

GDNF receptors as a drug target for neural repair

Bespalov, M. M., Hetenyi, C., Turnova, S., Hienola, A., Sidorova, Y., Rauvala, H., Karelson, M. & Saarma, M., 2007, In : Cell Transplantation. 16, 3, p. 314-314 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

New screening system demonstrates persephin potential in Parkinson's disease treatment

Sidorova, Y. A., Bespalov, M. M., Lindahl, M., Paveliev, M. & Saarma, M., Jun 2008, In : The FEBS Journal. 275, p. 465-465 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Retinal neuroprotection using small molecule GDNF mimetics

Saragovi, H. U., Sidorova, Y., Saarma, M. & Jmaeff, S., Apr 2014, In : Investigative Ophthalmology & Visual Science. 55, 13, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Role of CDNF in SOD1-G93A Mouse Model of Amyotrophic Lateral Sclerosis

Voutilainen, M. H., De Lorenzo, F., Montonen, E., Tuominen, R. K., Lindholm, D., Sendtner, M. & Saarma, M., Apr 2018, In : Cell Transplantation. 27, 4, p. 717-718 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Small Molecular Weight ARTN Mimetic for the Treatment of Neuropathic Pain

Sidorova, Y. A., Bespalov, M. M., Karelson, M. & Saarma, M., 2012, In : Cell Transplantation. 21, 4, p. 792-792 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Paper

GDNF mimetics delivery by porous silicon nanoparticles for improved Parkinson’s disease management

Li, W., Mäkilä, E., Salonen, J., Saarma, M., Sidorova, Y. & Almeida Santos, H., Jul 2018, p. 1848. 1 p.

Research output: Conference materialsPaper

Patent

Neurturin molecules

Bespalov, M., Saarma, M., Runeberg-Roos, P. M. & Penn, R., 18 Oct 2016, IPC No. A61K38/18, A61K48/00,C07K14/475 , Patent No. 9,469,679, 18 Oct 2016, Priority date 30 Oct 2009, Priority No. US201414469358 20140826

Research output: Patent

Review Article

c-Abl Inhibitors Enable Insights into the Pathophysiology and Neuroprotection in Parkinson's Disease

Lindholm, D., Pham, D. D., Cascone, A., Eriksson, O., Wennerberg, K. & Saarma, M., 26 Oct 2016, In : Frontiers in aging neuroscience. 8, 6 p., 254.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
File

Current disease modifying approaches to treat Parkinson's disease

Lindholm, D., Mäkelä, J., Di Liberto, V., Mudo, G., Belluardo, N., Eriksson-Rosenberg, O. & Saarma, M., Apr 2016, In : Cellular and Molecular Life Sciences. 73, 7, p. 1365-1379 15 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
File

GDNF family neurotrophic factor signaling: Four masters, one servant?

Airaksinen, M. S., Titievsky, A. & Saarma, M., 1999, In : Molecular and Cellular Neuroscience. 13, p. 313-325 13 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

GDNF family receptor complexes are emerging drug targets

Bespalov, M. M. & Saarma, M., 2007, In : Trends in Pharmacological Sciences. 28, 2, p. 68-74 7 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Glial cell line-derived neurotrophic factor family ligands and their therapeutic potential

Sidorova, Y. A. & Saarma, M., Jul 2016, In : Molecular Biology. 50, 4, p. 521-531 11 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Neurotrophic factor receptor RET: structure, cell biology, and inherited diseases

Runeberg-Roos, P. & Saarma, M., 2007, In : Annals of Medicine. 39, p. 572-580 9 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

NEUROTROPHIN RECEPTORS IN KIDNEY DEVELOPMENT

SAARMA, M., SAINIO, K., MOSHNYAKOV, M., SAXEN, L. & SARIOLA, H., 1993, In : Journal of Neurochemistry. 61, p. S179-S179 1 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

NEUROTROPHINS AND CILIARY NEUROTROPHIC FACTOR - THEIR BIOLOGY AND PATHOLOGY

SARIOLA, H., SAINIO, K., ARUMAE, U. & SAARMA, M., 1994, In : Annals of Internal Medicine. 26, p. 355-363 9 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Prospects of Neurotrophic Factors for Parkinson's Disease: Comparison of Protein and Gene Therapy

Domanskyi, A., Saarma, M. & Airavaara, M., 1 Aug 2015, In : Human Gene Therapy. 26, 8, p. 550-559 10 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Signalling mechanisms underlying development and maintenance of dopamine neurons

Andressoo, J-O. & Saarma, M., 2008, In : Current Opinion in Neurobiology. 18, 3, p. 297-306 10 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

The GDNF family: Signalling, biological functions and therapeutic value

Airaksinen, M. S. & Saarma, M., 2002, In : Nature Reviews. Neuroscience. 3, p. 383-394 12 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Therapeutic potential of the endoplasmic reticulum located and secreted CDNF/MANF family of neurotrophic factors in Parkinson's disease

Voutilainen, M. H., Arumäe, U., Airavaara, M. & Saarma, M., 21 Dec 2015, In : FEBS Letters. 589, 24, p. 3739-3748 10 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potential

Lindahl, M., Saarma, M. & Lindholm, P., Jan 2017, In : Neurobiology of Disease. 97, part B, p. 90-102 13 p.

Research output: Contribution to journalReview ArticleScientificpeer-review