Photo of Martin Puskarjov

Martin Puskarjov

Docent in Neuroscience, Doctor of Philosophy

20102020

Research output per year

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Publications

2020

Endogenous brain-sparing responses in brain pH and PO2 in a rodent model of birth asphyxia

Pospelov, A. S., Puskarjov, M., Kaila, K. & Voipio, J., Jul 2020, In : Acta Physiologica. 229, 3, 18 p., 13467.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Loss of non-canonical KCC2 functions promotes developmental apoptosis of cortical projection neurons

Mavrovic, M., Uvarov, P., Delpire, E., Vutskits, L., Kaila, K. & Puskarjov, M., 3 Apr 2020, In : EMBO Reports. 21, 4, 13 p., 48880.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2019

KCC2-Mediated Cl- Extrusion Modulates Spontaneous Hippocampal Network Events in Perinatal Rats and Mice

Spoljaric, I., Spoljaric, A., Mavrovic, M., Seja, P., Puskarjov, M. & Kaila, K., 29 Jan 2019, In : Cell Reports. 26, 5, p. 1073-+ 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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The primate-specific peptide Y-P30 regulates morphological maturation of neocortical dendritic spines

Neumann, J. R., Dash-Wagh, S., Jack, A., Raek, A., Juengling, K., Hamad, M. I. K., Pape, H-C., Kreutz, M. R., Puskarjov, M. & Wahle, P., 13 Feb 2019, In : PLoS One. 14, 2, 23 p., 0211151.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2018

Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's anti seizure efficacy

Brandt, C., Seja, P., Töllner, K., Römermann, K., Hampel, P., Kalesse, M., Kipper, A., Feit, P. W., Lykke, K., Toft-Bertelsen, T. L., Paavilainen, P., Spoljaric, I., Puskarjov, M., MacAulay, N., Kaila, K. & Löscher, W., Dec 2018, In : Neuropharmacology. 143, p. 186-204 19 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2017

K-Cl Cotransporter 2–mediated Cl− Extrusion Determines Developmental Stage–dependent Impact of Propofol Anesthesia on Dendritic Spines

Pushkarjov, M., Fiumelli, H., Briner, A., Bodogan, T., Demeter, K., Lacoh, C-M., Mavrovic, M., Blaesse, P., Kaila, K. K. & Vutskits, L., 2017, In : Anesthesiology. 126, 5, p. 855-867 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2016

Developmental Expression Patterns of KCC2 and Functionally Associated Molecules in the Human Brain

Sedmak, G., Jovanov-Milošević, N., Puskarjov, M., Ulamec, M., Krušlin, B., Kaila, K. K. & Judas, M., Dec 2016, In : Cerebral Cortex. 26, 12, p. 4574-4589 16 p., 26428952.

Research output: Contribution to journalArticleScientificpeer-review

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Forebrain-independent generation of hyperthermic convulsions in infant rats

Pospelov, A. S., Yukin, A. Y., Blumberg, M. S., Puskarjov, M. & Kaila, K., Jan 2016, In : Epilepsia. 57, 1, p. E1-E6 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2015

BDNF is required for seizure-induced but not developmental up-regulation of KCC2 in the neonatal hippocampus

Puskarjov, M., Ahmad, F., Khirug, S., Sivakumaran, S., Kaila, K. & Blaesse, P., 2015, In : Neuropharmacology. 88, p. 103-109 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2014

A variant of KCC2 from patients with febrile seizures impairs neuronal Cl- extrusion and dendritic spine formation

Puskarjov, M., Seja, P., Heron, S. E., Williams, T. C., Ahmad, F., Iona, X., Oliver, K. L., Grinton, B. E., Vutskits, L., Scheffer, I. E., Petrou, S., Blaesse, P., Dibbens, L. M., Berkovic, S. F. & Kaila, K., 25 Mar 2014, In : EMBO Reports. 15, 6, p. 723-729 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Cation-chloride cotransporters in neuronal development, plasticity and disease

Kaila, K., Price, T. J., Payne, J. A., Puskarjov, M. & Voipio, J., 2014, In : Nature Reviews. Neuroscience. 15, 10, p. 637-654 18 p.

Research output: Contribution to journalArticleScientificpeer-review

GABA actions and ionic plasticity in epilepsy

Kaila, K., Ruusuvuori, E., Seja, P., Voipio, J. & Puskarjov, M., Jun 2014, In : Current Opinion in Neurobiology. 26, p. 34-41 8 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Pharmacotherapeutic targeting of cation-chloride cotransporters in neonatal seizures

Puskarjov, M., Kahle, K. T., Ruusuvuori, E. & Kaila, K., 6 May 2014, In : Epilepsia. 55, 6, p. 806-818 13 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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2013

An Ion Transport-Independent Role for the Cation-Chloride Cotransporter KCC2 in Dendritic Spinogenesis In Vivo

Fiumelli, H., Briner, A., Puskarjov, M., Blaesse, P., Belem, B. J. T., Dayer, A. G., Kaila, K., Martin, J-L. & Vutskits, L., Feb 2013, In : Cerebral Cortex. 23, 2, p. 378-388 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Cation-chloride cotransporters NKCC1 and KCC2 as potential targets for novel antiepileptic and antiepileptogenic treatments

Loescher, W., Puskarjov, M. & Kaila, K., 2013, In : Neuropharmacology. 69, p. 62-74 13 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Modulation of neuronal activity by phosphorylation of the K-CI cotransporter KCC2

Kahle, K. T., Deeb, T. Z., Puskarjov, M., Silayeva, L., Liang, B., Kaila, K. & Moss, S. J., 2013, In : Trends in Neurosciences. 36, 12, p. 726-737 12 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

2012

Activity-Dependent Cleavage of the K-Cl Cotransporter KCC2 Mediated by Calcium-Activated Protease Calpain

Puskarjov, M., Ahmad, F., Kaila, K. & Blaesse, P., 2012, In : Journal of Neuroscience. 32, 33, p. 11356-11364 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2010

A Single Seizure Episode Leads to Rapid Functional Activation of KCC2 in the Neonatal Rat Hippocampus

Khirug, S., Ahmad, F., Puskarjov, M., Afzalov, R., Kaila, K. & Blaesse, P., 2010, In : Journal of Neuroscience. 30, 36, p. 12028-12035 8 p.

Research output: Contribution to journalArticleScientificpeer-review