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Publications 1991 2019

Anthology or special issue

Gastroenterologia ja hepatologia

Höckerstedt, K. (ed.), Aaltonen, L. A. (ed.), Kivilaakso, E. (ed.) & Färkkilä, M. (ed.), 2007, 1. [i.e. 3 täyd. uus.] p ed. Helsinki: Duodecim. 910 p.

Research output: Book/ReportAnthology or special issueScientificpeer-review

Article

(31)Phosphorus magnetic resonance spectroscopy of the liver for evaluating inflammation and fibrosis in autoimmune hepatitis

Puustinen, L., Hakkarainen, A., Kivisaari, R., Boyd, S., Nieminen, U., Färkkilä, M., Lundbom, N. & Arkkila, P., 2017, In : Scandinavian Journal of Gastroenterology. 52, 8, p. 886-892 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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A case report: Ulcerative colitis, treatment with an antibody against tumor necrosis factor (infliximab), and subsequent liver necrosis

Kinnunen, U., Färkkilä, M. A. & Mäkisalo, H., 2012, In : Journal of Crohn's and Colitis. 6, 6, p. 724-727 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Achievement of deep remission during scheduled maintenance therapy with TNF alpha-blocking agents in IBD

Molander, P., Sipponen, T., Kemppainen, H., Jussila, A., Blomster, T., Koskela, R., Nissinen, M., Rautiainen, H., Kuisma, J., Kolho, K-L. & Färkkilä, M. A., 1 Oct 2013, In : Journal of Crohn's and Colitis. 7, 9, p. 730-735 6 p.

Research output: Contribution to journalArticleScientificpeer-review

A High Prevalence of Gastrointestinal Manifestations in Common Variable Immunodeficiency

Pikkarainen, S., Martelius, T., Ristimäki, A., Siitonen, S., Seppanen, M. R. J. & Färkkilä, M., Apr 2019, In : American Journal of Gastroenterology. 114, 4, p. 648-655 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Aivokasvainten boori-neutronikaappaushoito

Translated title of the contribution: Boron neuron capture therapy in the treatment of brain tumorsKallio, M., Savolainen, S., Auterinen, I., Hiismäki, P., Kulvik, M., Vähätalo, J. & Färkkilä, M., 1996, In : Duodecim. 112, 11, p. 970-974 5 p.

Research output: Contribution to journalArticleProfessional

A Novel Fibrosis Index Comprising a Non-Cholesterol Sterol Accurately Predicts HCV-Related Liver Cirrhosis

Ydreborg, M., Lisovskaja, V., Lagging, M., Christensen, P. B., Langeland, N., Buhl, M. R., Pedersen, C., Morch, K., Wejstal, R., Norkrans, G., Lindh, M., Farkkila, M. & Westin, J., 3 Apr 2014, In : PLoS One. 9, 4, 8 p., 93601.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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A novel modification of a flow cytometric assay of phosphorylated STAT1 in whole blood monocytes for immunomonitoring of patients on IFN[alpha] regimen

Vakkila, J., Nieminen, U., Siitonen, S., Turunen, U., Halme, L., Nuutinen, H., Mustonen, H., Puolakkainen, P., Färkkilä, M. & Repo, H., 2008, In : Scandinavian Journal of Immunology. 67, 1, p. 95-102 8 p.

Research output: Contribution to journalArticleScientificpeer-review

A probiotic mixture alleviates symptoms in irritable bowel syndrome patients: a controlled 6-month intervention

Kajander, K., Hatakka, K., Poussa, T., Färkkilä, M. & Korpela, R., 2005, In : Alimentary Pharmacology & Therapeutics. 22 (, p. 387-394 8 p.

Research output: Contribution to journalArticleScientificpeer-review

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

Rivas, M. A., Graham, D., Sulem, P., Stevens, C., Desch, A. N., Goyette, P., Gudbjartsson, D., Jonsdottir, I., Thorsteinsdottir, U., Degenhardt, F., Mucha, S., Kurki, M. I., Li, D., D'Amato, M., Annese, V., Vermeire, S., Weersma, R. K., Halfvarson, J., Paavola-Sakki, A. L. P., Lappalainen, A. M. & 28 others, Lek, M., Cummings, B., Tukiainen, T., Haritunians, T., Halme, L., Koskinen, L. L. E., Ananthakrishnan, A. N., Luo, Y., Heap, G. A., Visschedijk, M. C., MacArthur, D. G., Neale, B. M., Ahmad, T., Anderson, C. A., Brant, S. R., Duerr, R. H., Silverberg, M. S., Cho, J. H., Palotie, A., Saavalainen, P., Kontula, K., Farkkila, M., McGovern, D. P. B., Franke, A., Stefansson, K., Rioux, J. D., Xavier, R. J. & Daly, M. J., Aug 2016, In : Nature Communications. 7, 7 p., 12342.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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A randomized, controlled study of peginterferon lambda-1a/ribavirin +/- daclatasvir for hepatitis C virus genotype 2 or 3

Foster, G. R., Chayama, K., Chuang, W-L., Fainboim, H., Farkkila, M., Gadano, A., Gaeta, G. B., Hezode, C., Inada, Y., Heo, J., Kumada, H., Lu, S-N., Marcellin, P., Moreno, C., Roberts, S. K., Strasser, S. I., Thompson, A. J., Toyota, J., Paik, S. W., Vierling, J. M. & 8 others, Zignego, A. L., Cohen, D., McPhee, F., Wind-Rotolo, M., Srinivasan, S., Hruska, M., Myler, H. & Portsmouth, S. D., 19 Aug 2016, In : SpringerPlus. 5, 12 p., 1365.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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A randomized comparison of target-controlled propofol infusion and patient-controlled sedation during ERCP

Mazanikov, M., Udd, M., Kylänpää, M-L., Mustonen, H., Lindström, O. K., Färkkilä, M. A., Halttunen, J. & Pöyhiä, R., Nov 2013, In : Endoscopy. 45, 11, p. 915-919 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Association of celiac disease genes with inflammatory bowel disease in Finnish and Swedish patients

Parmar, A., Lappalainen, A. M., Paavola-Sakki, A. L. P., Halme, L., Färkkilä, M. A., Turunen, U., Kontula, K., Aromaa, A., Salomaa, V., Palotie, L., Halfvarson, J., Törkvist, L., D´Amato, M., Saavalainen, P. M. & Einarsdottir, E., 2012, In : Genes and Immunity. 13, 6, p. 474-480 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Association study of FUT2 (rs601338) with celiac disease and inflammatory bowel disease in the Finnish population

Parmar, A. S., Alakulppi, N., Paavola-Sakki, A. L. P., Kurppa, K., Halme, L., Färkkilä, M. A., Turunen, U., Lappalainen, M., Kontula, K., Kaukinen, K., Maki, M., Lindfors, K., Partanen, J., Sistonen, P., Matto, J., Wacklin, P., Saavalainen, P. & Einarsdottir, E., Dec 2012, In : Tissue Antigens. 80, 6, p. 488-493 6 p.

Research output: Contribution to journalArticleScientificpeer-review

B-hepatiitin muuttunut lääkehoito

Färkkilä, M., 2009, In : Suomen lääkärilehti. 64, p. 1225-1231 7 p.

Research output: Contribution to journalArticleScientific

Bile microbiota in primary sclerosing cholangitis: Impact on disease progression and development of biliary dysplasia

Pereira, P., Aho, V., Arola, J., Boyd, S., Jokelainen, K., Paulin, L., Auvinen, P. & Farkkila, M., 10 Aug 2017, In : PLoS One. 12, 8, 15 p., 0182924.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Biliary Anomalies in Patients With HNF1B Diabetes

Kettunen, J. L. T., Parviainen, H., Miettinen, P. J., Färkkilä, M., Tamminen, M., Salonen, P., Lantto, E. & Tuomi, T., Jun 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 6, p. 2075-2082 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Biliary dysplasia in patients with primary sclerosing cholangitis: additional value of DNA ploidity

Halme, L., Arola, J., Numminen, K., Krogerus, L., Mäkisalo, H. & Färkkilä, M. A., 2012, In : Liver International. 32, 5, p. 783-789 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Budesonide combined with UDCA to improve liver histology in primary biliary cirrhosis: a three-year randomized trial

Rautiainen, H., Kärkkäinen, P., Karvonen, A. -L., Nurmi, H., Pikkarainen, P., Nuutinen, H. & Färkkilä, M., 2005, In : Hepatology. 41, p. 747-752 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Budesonide Induces Remission More Effectively Than Prednisone in a Controlled Trial of Patients With Autoimmune Hepatitis

Manns, M. P., Woynarowski, M., Kreisel, W., Lurie, Y., Rust, C., Zuckerman, E., Bahr, M. J., Guenther, R., Hultcrantz, R. W., Spengler, U., Lohse, A. W., Szalay, F., Färkkilä, M. A., Proels, M., Strassburg, C. P. & European AIH-BUC-STUDY GRP, 2010, In : Gastroenterology. 139, 4, p. 1198-1206 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Cancer incidence among alcoholic liver disease patients in Finland: A retrospective registry study during years 1996-2013

Sahlman, P., Nissinen, M., Pukkala, E. & Farkkila, M., 1 Jun 2016, In : International Journal of Cancer. 138, 11, p. 2616-2621 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Capsule endoscopy in pediatric patients: Technique and results in our first 100 consecutive children

Nuutinen, H., Kolho, K-L., Salminen, P., Rintala, R., Koskenpato, J., Koivusalo, A., Sipponen, T. & Färkkilä, M., 2011, In : Scandinavian Journal of Gastroenterology. 46, 9, p. 1138-1143 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Celiac disease in patients with severe liver disease: gluten-free diet may reverse hepatic failure

Kaukinen, K., Halme, L., Collin, P., Färkkilä, M., Mäki, M., Vehmanen, P., Partanen, J. & Höckerstedt, K., Apr 2002, In : Gastroenterology. 122, 4, p. 881-888 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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C-hepatiitin hoito : kenelle ja milloin?

Färkkilä, M., 2016, In : Duodecim. 132, 18, p. 1681-1683 3 p.

Research output: Contribution to journalArticleProfessional

Open Access
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Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial

Laharie, D., Bourreille, A., Branche, J., Allez, M., Bouhnik, Y., Filippi, J., Zerbib, F., Savoye, G., Nachury, M., Moreau, J., Delchier, J-C., Cosnes, J., Ricart, E., Dewit, O., Lopez-Sanroman, A., Dupas, J-L., Carbonnel, F., Bommelaer, G., Coffin, B., Roblin, X. & 12 others, Van Assche, G., Esteve, M., Färkkilä, M. A., Gisbert, J. P., Marteau, P., Nahon, S., de Vos, M., Franchimont, D., Mary, J-Y., Colombel, J-F., Lemann, M. & Affect, G. E. T. D., 1 Dec 2012, In : Lancet. 380, 9857, p. 1909-1915 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Clinical course and prognosis of pediatric-onset primary sclerosing cholangitis

Tenca, A., Farkkila, M., Arola, J., Jaakkola, T., Penagini, R. & Kolho, K-L., Aug 2016, In : United european gastroenterology journal. 4, 4, p. 562-569 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Clinical value of ultrasound in the evaluation of dyspepsia in primary health care

Heikkinen, M., Räsänen, H. & Färkkilä, M., 2005, In : Scandinavian Journal of Gastroenterology. 40, p. 980-984 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo)

Maret-Ouda, J., Wahlin, K., Artama, M., Brusselaers, N., Farkkila, M., Lynge, E., Mattsson, F., Pukkala, E., Romundstad, P., Tryggvadottir, L., von Euler-Chelpin, M. & Lagergren, J., Jun 2017, In : BMJ Open. 7, 6, 8 p., 016505.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Comorbidity and use of health-care services among irritable bowel syndrome sufferers

Hillilä, M. T., Siivola, M. T., Färkkilä, M. & Färkkilä, M. A., 2007, In : Scandinavian Journal of Gastroenterology. 42, 7, p. 799-806 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Correlation of faecal calprotectin and lactoferrin with an endoscopic score for Crohn's disease and histological findings

Sipponen, T., Kärkkäinen, P., Savilahti, E., Kolho, K-L., Nuutinen, H., Turunen, U. & Färkkilä, M., 2008, In : Alimentary Pharmacology & Therapeutics. 28, p. 1221-1229 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Crohn's disease activity assessed by fecal calprotectin and lactoferrin: correlation with Crohn's disease activity index and endoscopic findings

Sipponen, T., Savilahti, E., Kolho, K-L., Nuutinen, H., Turunen, U. & Färkkilä, M., 2008, In : Inflammatory Bowel Diseases. 14, p. 40-46 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Cure of Helicobacter pylori infection after failed primary treatment: One-center results from 120 patients

Seppala, K., Kosunen, T. U., Nuutinen, H., Sipponen, P., Rautelin, H. I., Sarna, S., Hyvarinen, H., Färkkilä, M. A. & Miettinen, T. A., 2000, In : Scandinavian Journal of Gastroenterology. 35, p. 929-934 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Dendritic Cells from Crohn's Disease Patients Show Aberrant STAT1 and STAT3 Signaling

Nieminen, J. K., Niemi, M., Sipponen, T., Salo, H. M., Klemetti, P., Färkkilä, M. A., Vakkila, J. & Vaarala, O., 7 Aug 2013, In : PLoS One. 8, 8, p. Article Number: e70738 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

Liu, J. Z., Hov, J. R., Folseraas, T., Ellinghaus, E., Rushbrook, S. M., Doncheva, N. T., Andreassen, O. A., Weersma, R. K., Weismueller, T. J., Eksteen, B., Invernizzi, P., Hirschfield, G. M., Gotthardt, D. N., Pares, A., Ellinghaus, D., Shah, T., Juran, B. D., Milkiewicz, P., Rust, C., Schramm, C. & 33 others, Mueller, T., Srivastava, B., Dalekos, G., Noethen, M. M., Herms, S., Winkelmann, J., Mitrovic, M., Braun, F., Ponsioen, C. Y., Croucher, P. J. P., Sterneck, M., Teufel, A., Mason, A. L., Saarela, J., Leppä, V., Dorfman, R., Alvaro, D., Floreani, A., Onengut-Gumuscu, S., Rich, S. S., Thompson, W. K., Schork, A. J., Naess, S., Thomsen, I., Mayr, G., Koenig, I. R., Hveem, K., Cleynen, I., Gutierrez-Achury, J., Färkkilä, M. A., UK-PSCSC Consortium, Int IBD Genetics Consortium & Int PSCSC Study Grp, Jun 2013, In : Nature Genetics. 45, 6, p. 670-+ 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Does Fecal Calprotectin Predict Short-Term Relapse After Stopping Tnfα-Blocking Agents In Inflammatory Bowel Disease Patients In Deep Remission?

Molander, P., Farkkila, M., Ristimaki, A., Salminen, K., Kemppainen, H., Blomster, T., Koskela, R., Jussila, A., Rautiainen, H., Nissinen, M., Haapamaki, J., Arkkila, P., Nieminen, U., Kuisma, J., Punkkinen, J., Kolho, K-L., Mustonen, H. & Sipponen, T., 1 Jan 2015, In : Journal of Crohn's and Colitis. 9, 1, p. 33-40 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Does oral α-galactosidase relieve irritable bowel symptoms?

Hillilä, M., Farkkila, M. A., Sipponen, T., Rajala, J. & Koskenpato, J., 2 Jan 2016, In : Scandinavian Journal of Gastroenterology. 51, 1, p. 16-21 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Early Determination of Hepatitis C Virus RNA May Help to Decide the Duration of Therapy for Chronic Hepatitis C Virus Genotype 2/3 Infection

Lagging, M., Alsio, A., Langeland, N., Pedersen, C., Farkkila, M., Buhl, M. R., Morch, K., Hellstrand, K. & Norkrans, G., 2011, In : Hepatology. 53, p. 1067-1068 2 p.

Research output: Contribution to journalArticleScientificpeer-review

Early quantification of HCV core antigen may help to determine the duration of therapy for chronic genotype 2 or 3 HCV infection

Alsio, A., Jannesson, A., Langeland, N., Pedersen, C., Färkkilä, M. A., Buhl, M. R., Morch, K., Westin, J., Hellstrand, K., Norkrans, G., Lagging, M. & NORDynamIC Study Grp, 2012, In : European Journal of Clinical Microbiology & Infectious Diseases. 31, 7, p. 1631-1635 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect of Lactobacillus rhamnosus GG on ileal pouch inflammation and microbial flora

Kuisma, J., Mentula, S., Järvinen, H., Kahri, A., Saxelin, M. & Färkkilä, M., 15 Feb 2003, In : Alimentary Pharmacology & Therapeutics. 17, 4, p. 509-515 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Effect of smoking on gastric histology in Helicobacter pylori-positive gastritis

Koivisto, T. T., Voutilainen, M. E., Färkkilä, M. & Färkkilä, M. A., 2008, In : Scandinavian Journal of Gastroenterology. 43, p. 1177-1183 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect of steatosis and inflammation on liver fibrosis in chronic hepatitis C

Nieminen, U., Arkkila, P. E. T., Kärkkäinen, P. & Färkkilä, M. A., 2009, In : Liver International. 29, p. 153-158 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Endoscopic Evaluation of Crohn's Disease Activity: Comparison of the CDEIS and the SES-CD

Sipponen, T., Nuutinen, H., Turunen, U. & Farkkila, M., 2010, In : Inflammatory Bowel Diseases. 16, p. 2131-2136 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Endoscopic Monitoring of Infliximab Therapy in Crohn's Disease

af Bjorkesten, C-G., Nieminen, U., Turunen, U., Arkkila, P. E., Sipponen, T. & Farkkila, M. A., 2011, In : Inflammatory Bowel Diseases. 17, p. 947-953 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Enhanced liver fibrosis score predicts transplant-free survival in primary sclerosing cholangitis

Vesterhus, M., Hov, J. R., Holm, A., Schrumpf, E., Nygard, S., Godang, K., Andersen, I. M., Naess, S., Thorburn, D., Saffioti, F., Vatn, M., Gilja, O. H., Lund-Johansen, F., Syversveen, T., Brabrand, K., Pares, A., Ponsioen, C. Y., Pinzani, M., Farkkila, M., Moum, B. & 5 others, Ueland, T., Rosjo, H., Rosenberg, W., Boberg, K. M. & Karlsen, T. H., Jul 2015, In : Hepatology. 62, 1, p. 188-197 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Enhanced liver fibrosis test predicts transplant-free survival in primary sclerosing cholangitis, a multi-centre study

de Vries, E. M. G., Farkkila, M., Milkiewicz, P., Hov, J. R., Eksteen, B., Thorburn, D., Chazouilleres, O., Pares, A., Nygard, S., Gilja, O. H., Wunsch, E., Invernizzi, P., Carbone, M., Bernuzzi, F., Boberg, K. M., Rosjo, H., Rosenberg, W., Beuers, U. H., Ponsioen, C. Y., Karlsen, T. H. & 1 others, Vesterhus, M., Oct 2017, In : Liver International. 37, 10, p. 1554-1561 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Eradication of Helicobacter pylori improves the healing rate and reduces the relapse rate of nonbleeding ulcers in patients with bleeding peptic ulcer

Arkkila, P. E. T., Seppälä, K., Kosunen, T. U., Haapiainen, R., Kivilaakso, E., Sipponen, P., Mäkinen, J., Nuutinen, H., Rautelin, H. & Färkkilä, M. A., Oct 2003, In : American Journal of Gastroenterology. 98, 10, p. 2149-2156 8 p.

Research output: Contribution to journalArticleScientificpeer-review