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Personal profile

Curriculum vitae

EDUCATION

2017 — present

PhD student of the Doctoral Programme in Biomedicine, University of Helsinki, Finland. 

2015 – 2017 

Master of Medical Science in Biomedicine, Faculty of Medicine, Lund University, Sweden. Graduation date: March 15th, 2017.

2012 – 2015

Bachelor of Science in Cell Biology, Faculty of Science and Engineering, Åbo Akademi University, Finland. Graduation date: May 27th, 2015. Grade: 5 (A), excellent.

 

WORK EXPERIENCE

6-7/2018, 7-8/2019, 11/2019, 3/2020

Graduate Research Assistant in Tuomas Tammela’s lab at Memorial Sloan Kettering Cancer Center, New York, USA. Worked on a project investigating intratumor heterogeneity in pancreatic cancer. Techniques include 2D, 3D, and primary cell culture, immunohistochemistry, in situ hybridization, immunofluorescence, and RT-qPCR. 

5/2017 – present

PhD project in Caj Haglund’s Translational Cancer Medicine group and Ari Ristimäki’s Applied Tumor Genomics group at the University of Helsinki, Helsinki, Finland. My project focuses on the glycomic and proteomic profiling of colorectal cancer, done by analyzing tissue and plasma samples using mass spectrometry.

9/2016 – 3/2017

Master’s thesis project about liver cancer in the Molecular Tumor Pathology group at Lund University, Lund, Sweden. Techniques include cell culture, Western Blot, RT-qPCR, RNAi using shRNA, immunofluorescence, and plasmid isolation.

6-7/2016

Summer project focusing on melanoma in the Molecular Tumor Pathology group at Lund University, Sweden.

5/2016 – 4/2017

Part-time animal caretaker at Timeline Bioresearch AB, Lund, Sweden.

6-8/2014, 6-8/2015 

Summer internships at the Toivola Epithelial Biology Lab, Åbo Akademi University, Turku, Finland. Research focused on keratins in the colon.

 

SCHOLARSHIPS AND GRANTS

2020

Kurt and Doris Palander Foundation for Medical Research scholarship 
The Magnus Ehrnrooth Foundation travel grant 
Doctoral School in Health Sciences travel grant 
Finska Läkaresällskapets scholarship for doctoral students 

2019

The Finnish Cancer Foundation (Syöpäjärjestöt) doctoral student grant 
Medicinska Understödsföreningen Liv och Hälsa grant 
Doctoral School in Health Sciences travel grant
Finska Läkaresällskapets scholarship for doctoral students 

2018

Kurt and Doris Palander Foundation for Medical Research scholarship 
Finska Läkaresällskapets scholarship for doctoral students 

2016 

Summer scholarship for students of the Faculty of Medicine 

2015

Scholarship for excellent scholarly achievement from Svenska Studiefonden
Åbo Akademi University’s general scholarships for excellent achievement during undergraduate studies 

2014

Åbo Akademi University’s general scholarships for excellent achievement during undergraduate studies


 

 

External positions

Graduate Research Assistant, Memorial Sloan Kettering Cancer Center

International and National Collaboration Publications and projects within past five years.

Publications

Label-free proteomics reveals serum proteins whose levels differ between pancreatic ductal adenocarcinoma patients with short or long survival

Holm, M., Saraswat, M., Joenväärä, S., Seppänen, H., Renkonen, R. & Haglund, C., 25 Jun 2020, In : Tumor Biology. 42, 6, 10 p., 1010428320936410.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

N-glycomic profiling of colorectal cancer according to tumor stage and location

Holm, M., Nummela, P., Heiskanen, A., Satomaa, T., Kaprio, T., Mustonen, H., Ristimäki, A. & Haglund, C., 29 Jun 2020, In : PLoS One. 15, 6, 16 p., e0234989.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Plasma protein expression differs between colorectal cancer patients depending on primary tumor location

Holm, M., Joenväärä, S., Saraswat, M., Tohmola, T., Ristimäki, A., Renkonen, R. & Haglund, C., 26 May 2020, In : Cancer medicine . 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Preoperative Radiotherapy Leads to Significant Differences in the Plasma Protein Profile of Rectal Cancer Patients

Holm, M., Joenväärä, S., Saraswat, M., Tohmola, T., Ristimäki, A., Renkonen, R. & Haglund, C., Jul 2020, In : Oncology. 98, 7, p. 493-500 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Differences and overlap in plasma protein expression during colorectal cancer progression

Holm, M., Joenväärä, S., Saraswat, M., Tohmola, T., Ristimäki, A., Renkonen, R. & Haglund, C., 5 Aug 2019, In : Translational Medicine Communications. 4, 1, 12 p., 14.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Activities

  • 2 Academic visit to other institution

Memorial Sloan Kettering Cancer Center

Matilda Holm (Visiting researcher)
Jul 2019Aug 2019

Activity: Visiting an external institution typesAcademic visit to other institution

Memorial Sloan Kettering Cancer Center

Matilda Holm (Visiting researcher)
Jun 2018Aug 2018

Activity: Visiting an external institution typesAcademic visit to other institution