Research output per year
Research output per year
Personal profile
Fields of Science
- 3121 General medicine, internal medicine and other clinical medicine
- 318 Medical biotechnology
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Clinical studies on pharmacokinetic drug-drug interactions caused by clopidogrel : focus on CYP2C8-mediated drug metabolism
Itkonen, M., 2019, Helsinki. 83 p.Research output: Thesis › Doctoral Thesis › Collection of Articles
Open Access -
Clopidogrel and Gemfibrozil Strongly Inhibit the CYP2C8-Dependent Formation of 3-Hydroxydesloratadine and Increase Desloratadine Exposure In Humans
Itkonen, M. K., Tornio, A., Neuvonen, M., Neuvonen, P. J., Niemi, M. & Backman, J. T., 1 Apr 2019, In: Drug Metabolism and Disposition. 47, 4, p. 377-385 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Clopidogrel Increases Dasabuvir Exposure With or Without Ritonavir, and Ritonavir Inhibits the Bioactivation of Clopidogrel
Itkonen, M. K., Tornio, A., Lapatto-Reiniluoto, O., Neuvonen, M., Neuvonen, P. J., Niemi, M. & Backman, J. T., Jan 2019, In: Clinical Pharmacology and Therapeutics. 105, 1, p. 219-228 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Response to "Interaction of Dasabuvir With Clopidogrel: Did Predictions by Physiologically Based Pharmacokinetics Modeling Pass the Test?"
Itkonen, M. K., Tornio, A., Lapatto-Reiniluoto, O., Neuvonen, M., Neuvonen, P. J., Niemi, M. & Backman, J. T., Feb 2019, In: Clinical Pharmacology and Therapeutics. 105, 2, p. 322-322 1 p.Research output: Contribution to journal › Letter › Scientific
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Clopidogrel but Not Prasugrel Significantly Inhibits the CYP2C8-Mediated Metabolism of Montelukast in Humans.
Itkonen, M. K., Tornio, A., Filppula, A. M., Neuvonen, M., Neuvonen, P. J., Niemi, M. & Backman, J. T., Sep 2018, In: Clinical Pharmacology and Therapeutics. 104, 3, p. 495-504 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
Projects
- 1 Finished
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Academy of Finland Project Funding: Mechanism-Based Inactivation of Cytochrome P450 (Palautumaton sytokromi P450-entsyymien esto ja kliinisesti merkittävät lääkeaineyhteisvaikutukset: Yhteisvaikutuksia in vitro tiedosta ennustavien menetelmien kehittäminen)
Backman, J., Niemi, M., Tornio, A., Filppula, A. M., Neuvonen, P., Neuvonen, M., Launiainen, T., Kahma, H., Kaartinen, T. & Itkonen, M.
01/09/2014 → 31/08/2018
Project: Research project
Activities
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First Nordic Conference on Personalized Medicine
Matti Itkonen (Poster Presentation)
30 May 2018 → 1 Jun 2018Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Nordic Drug Information Meeting
Matti Itkonen (Attendee)
24 Sep 2018 → 25 Sep 2018Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Improving Rational Pharmacotherapy - 50 Years of Clinical Pharmacology in Finland symposium
Matti Itkonen (Speaker)
8 Nov 2018 → 9 Nov 2018Activity: Talk or presentation types › Oral presentation
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14th European ISSX Meeting
Matti Itkonen (Poster Presentation)
26 Jun 2017 → 29 Jun 2017Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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EPHAR2016 - 7th European Congress of Pharmacology
Matti Itkonen (Poster Presentation)
26 Jun 2016 → 30 Jun 2016Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Press/Media
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Suomessakin suositut Aloe vera -tuotteet huijausta? Lääkäri: voi aiheuttaa maksavaurioita
14/07/2016
1 Media contribution
Press/Media: Press / Media
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