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Publications 2015 2019

2019
Open Access
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Open Access
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2018

Clopidogrel but Not Prasugrel Significantly Inhibits the CYP2C8-Mediated Metabolism of Montelukast in Humans.

Itkonen, M. K., Tornio, A., Filppula, A. M., Neuvonen, M., Neuvonen, P. J., Niemi, M. & Backman, J. T., Sep 2018, In : Clinical Pharmacology and Therapeutics. 104, 3, p. 495-504 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions

Kahma, H., Filppula, A. M., Neuvonen, M., Tarkiainen, E. K., Tornio, A., Holmberg, M. T., Itkonen, M. K., Finel, M., Neuvonen, P. J., Niemi, M. & Backman, J. T., 1 Feb 2018, In : Drug Metabolism and Disposition. 46, 2, p. 141-150 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Effects of Genetic Variants on Carboxylesterase 1 Gene Expression, and Clopidogrel Pharmacokinetics and Antiplatelet Effects

Neuvonen, M., Tarkiainen, E. K., Tornio, A., Hirvensalo, P., Tapaninen, T., Paile-Hyvärinen, M., Itkonen, M. K., Holmberg, M. T., Karja, V., Männistö, V. T., Neuvonen, P. J., Pihlajamäki, J., Backman, J. T. & Niemi, M., Mar 2018, In : Basic & Clinical Pharmacology & Toxicology. 122, 3, p. 341-345 5 p.

Research output: Contribution to journalArticleScientificpeer-review

2016

Clopidogrel Markedly Increases Plasma Concentrations of CYP2C8 Substrate Pioglitazone

Itkonen, M. K., Tornio, A., Neuvonen, M., Neuvonen, P. J., Niemi, M. & Backman, J. T., Aug 2016, In : Drug Metabolism and Disposition. 44, 8, p. 1364-1371 8 p.

Research output: Contribution to journalArticleScientificpeer-review