20112020

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2020

Age-associated changes in the immune system may influence the response to anti-PD1 therapy in metastatic melanoma patients

Kasanen, H., Hernberg, M., Mäkelä, S., Brück, O., Juteau, S., Kohtamäki, L., Ilander, M., Mustjoki, S. & Kreutzman, A., May 2020, In : Cancer Immunology, Immunotherapy. 69, 5, p. 717-730 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Immune profiles in acute myeloid leukemia bone marrow associate with patient age, T-cell receptor clonality, and survival

Brück, O., Dufva, O., Hohtari, H., Blom, S., Turkki, R., Ilander, M., Kovanen, P., Pallaud, C., Ramos, P. M., Lähteenmäki, H., Välimäki, K., El Missiry, M., Ribeiro, A., Kallioniemi, O., Porkka, K., Pellinen, T. & Mustjoki, S., 28 Jan 2020, In : Blood advances. 4, 2, p. 274-286 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Plasma proteomics of biomarkers for inflammation or cancer cannot predict relapse in chronic myeloid leukaemia patients stopping tyrosine kinase inhibitor therapy

Soderlund, S., Persson, I., Ilanderd, M., Guilhot, J., Hjorth-Hansen, H., Koskenvesa, P., Richter, J., Saussele, S., Mustjoki, S. & Olsson-Strömberg, U., Mar 2020, In : Leukemia Research. 90, 7 p., 106310.

Research output: Contribution to journalArticleScientificpeer-review

2019

Novel TMEM173 Mutation and the Role of Disease Modifying Alleles

Keskitalo, S., Haapaniemi, E., Einarsdottir, E., Rajamäki, K., Heikkilä, H., Ilander, M., Pöyhönen, M., Morgunova, E., Hokynar, K., Lagström, S., Kivirikko, S., Mustjoki, S., Eklund, K., Saarela, J., Kere, J., Seppänen, M. R. J., Ranki, A., Hannula-Jouppi, K. & Varjosalo, M., 5 Dec 2019, In : Frontiers in Immunology. 10, 17 p., 2770.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy

Haikala, H. M., Anttila, J. M., Marques, E., Raatikainen, T., Ilander, M., Hakanen, H., Ala-Hongisto, H., Savelius, M., Balboa, D., Von Eyss, B., Eskelinen, V., Munne, P., Nieminen, A. I., Otonkoski, T., Schüler, J., Laajala, T. D., Aittokallio, T., Sihto, H., Mattson, J., Heikkilä, P. & 7 others, Leidenius, M., Joensuu, H., Mustjoki, S., Kovanen, P., Eilers, M., Leverson, J. D. & Klefström, J., 6 Feb 2019, In : Nature Communications. 10, 17 p., 620.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2018

Divergent roles for antigenic drive in the aetiology of primary versus dasatinib-associated CD8(+) TCR-Vβ(+) expansions

Lissina, A., McLaren, J. E., Ilander, M., Andersson, E. I., Lewis, C. S., Clement, M., Herman, A., Ladell, K., Llewellyn-Lacey, S., Miners, K. L., Gostick, E., Melenhorst, J. J., Barrett, A. J., Price, D. A., Mustjoki, S. & Wooldridge, L., 7 Feb 2018, In : Scientific Reports. 8, 12 p., 2534.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Immune cell phenotype and functional defects in Netherton syndrome

Eränkö, E., Ilander, M., Tuomiranta, M., Mäkitie, A., Lassila, T., Kreutzman, A., Klemetti, P., Mustjoki, S., Hannula-Jouppi, K. & Ranki, A., 26 Nov 2018, In : Orphanet journal of rare diseases. 13, 10 p., 213.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2017

Combined immunodeficiency and hypoglycemia associated with mutations in hypoxia upregulated 1

Haapaniemi, E. M., Fogarty, C., Keskitalo, S., Katayama, S., Vihinen, H., Ilander, M., Mustjoki, S., Krjutskov, K., Lehto, M., Hautala, T., Eriksson-Rosenberg, O., Jokitalo, E., Velagapudi, V., Varjosalo, M., Seppanen, M. & Kere, J., Apr 2017, In : Journal of Allergy and Clinical Immunology. 139, 4, p. 1391-+ 14 p.

Research output: Contribution to journalArticleScientific

Open Access
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Dasatinib Changes Immune Cell Profiles Concomitant with Reduced Tumor Growth in Several Murine Solid Tumor Models

Hekim, C., Ilander, M., Yan, J., Michaud, E., Smykla, R., Vaha-Koskela, M., Savola, P., Tahtinen, S., Saikko, L., Hemminki, A., Kovanen, P. E., Porkka, K., Lee, F. Y. F. & Mustjoki, S., Feb 2017, In : Cancer immunology research. 5, 2, p. 157-169 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Dasatinib Reversibly Disrupts Endothelial Vascular Integrity by Increasing Non-Muscle Myosin II Contractility in a ROCK-Dependent Manner

Kreutzman, A., Colom-Fernandez, B., Marcos Jimenez, A., Ilander, M., Cuesta-Mateos, C., Perez-Garcia, Y., Delgado Arevalo, C., Bruck, O., Hakanen, H., Saarela, J., Ortega-Carrion, A., de Rosendo, A., Juanes-Garcia, A., Luis Steegmann, J., Mustjoki, S., Vicente-Manzanares, M. & Munoz-Calleja, C., 1 Nov 2017, In : Clinical Cancer Research. 23, 21, p. 6697-6707 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Increased proportion of mature NK cells is associated with successful imatinib discontinuation in chronic myeloid leukemia

Ilander, M., Olsson-Stromberg, U., Schlums, H., Guilhot, J., Bruck, O., Lahteenmaki, H., Kasanen, T., Koskenvesa, P., Soderlund, S., Hoglund, M., Markevarn, B., Sjalander, A., Lotfi, K., Dreimane, A., Lubking, A., Holm, E., Bjoreman, M., Lehmann, S., Stenke, L., Ohm, L. & 11 others, Gedde-Dahl, T., Majeed, W., Ehrencrona, H., Koskela, S., Saussele, S., Mahon, F-X., Porkka, K., Hjorth-Hansen, H., Bryceson, Y. T., Richter, J. & Mustjoki, S., May 2017, In : Leukemia. 31, 5, p. 1108-1116 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
2016

Intrafamily and Interfamilial Phenotype Variation and Immature Immunity in Patients With Netherton Syndrome and Finnish SPINK5 Founder Mutation

Hannula-Jouppi, K., Laasanen, S-L., Ilander, M., Furio, L., Tuomiranta, M., Marttila, R., Jeskanen, L., Häyry, V., Kanerva, M., Kivirikko, S., Tuomi, M-L., Heikkila, H., Mustjoki, S., Hovnanian, A. & Ranki, A., Apr 2016, In : Jama dermatology. 152, 4, p. 435-442 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
2014

Dasatinib promotes Th1-type responses in granzyme B expressing T-cells

Kreutzman, A., Ilander, M., Porkka, K., Vakkila, J. & Mustjoki, S., 1 May 2014, In : OncoImmunology. 3, e28925.

Research output: Contribution to journalArticleScientificpeer-review

Enlarged Memory T-Cell Pool and Enhanced Th1-Type Responses in Chronic Myeloid Leukemia Patients Who Have Successfully Discontinued IFN-alpha Monotherapy

Ilander, M., Kreutzman, A., Rohon, P., Melo, T., Faber, E., Porkka, K., Vakkila, J. & Mustjoki, S., 31 Jan 2014, In : PLoS One. 9, 1, 11 p., 87794.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Immunology and Immunotherapy of Chronic Myeloid Leukemia

Ilander, M., Hekim, C. & Mustjoki, S., Mar 2014, In : Current hematologic malignancy reports. 9, 1, p. 17-23 7 p.

Research output: Contribution to journalArticleScientificpeer-review

2011

Intracerebral Borna disease virus infection of bank voles leading to peripheral spread and reverse transcription of viral RNA

Kinnunen, P. M., Inkeroinen, H., Ilander, M., Kallio, E. R., Heikkilä, H. P., Koskela, E., Mappes, T., Palva, A., Vaheri, A., Kipar, A. & Vapalahti, O., 2011, In : PLoS One. 6, 8, p. e23622 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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