19992022

Research output per year

If you made any changes in Pure these will be visible here soon.

Publications

2020
Open Access
File
Open Access
File
2019

Research in Specialization Studies in Industrial Pharmacy benefits pharmaceutical industry

Juppo, A. & Siven, M., 2019, In : Dosis : farmaseuttinen aikakauskirja. 35, 1, p. 90-96 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
2017

Challenge of paediatric compounding to solid dosage forms sachets and hard capsules - Finnish perspective

Siven, M., Kovanen, S., Siirola, O., Hepojoki, T., Isokirmo, S., Laihanen, N., Eränen, T., Pellinen, J. & Juppo, A. M., May 2017, In : Journal of Pharmacy and Pharmacology. 69, 5, p. 593-602 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Difficulties in administration of oral medication formulations to pet cats: an e-survey of cat owners

Sivén, M., Savolainen, S., Räntilä, S., Männikkö, S., Vainionpää, M., Airaksinen, S., Raekallio, M., Vainio, O. & Juppo, A. M., 10 Mar 2017, In : Veterinary Record. 180, 10, 6 p., 250.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
2016

Vastaavatko nykyiset lääkemuodot iäkkäiden lääkehoidon haasteisiin?

Translated title of the contribution: How does the current dosage forms meet the needs of drug treatment in older adults?Siven, M. S. & Niittymäki, J., 2016, In : Dosis : farmaseuttinen aikakauskirja. 32, 1, p. 75-83 9 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
File
2013

Permeability and toxicity characteristics of L-cysteine and 2-methyl-thiazolidine-4-carboxylic acid in Caco-2 cells

Kartal-Hodzic, A., Marvola, T., Schmitt, M., Harju, K., Peltoniemi, M. & Siven, M., Nov 2013, In : Pharmaceutical Development and Technology. 18, 6, p. 1288-1293 5 p.

Research output: Contribution to journalArticleScientificpeer-review

2012

Difficulties in oral medication of pet cats in Finland

Savolainen, S. M., Räntilä, S., Raekallio, M. R., Vainio-Kivinen, O. M., Siven, M. S., Airaksinen, S. T. T. & Juppo, A. M., 2012, Special Issue: Abstracts of the 12th International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT 2012). Blackwell Publishing, Vol. 35. p. 24-25 (Journal of Veterinary Pharmacology and Therapeutics; vol. 35, no. s3).

Research output: Chapter in Book/Report/Conference proceedingConference contributionProfessional

Difficulties in oral medication of pet cats in Finland

Savolainen, S. M., Räntilä, SK., Raekallio, M. R., Vainio-Kivinen, O. M., Siven, M. S., Airaksinen, S. & Juppo, A. M., 2012, Proceedings of the 12th International Congress of the European Association for Veterinary Pharmacology and Toxicology, 8.-12.7.2012. p. 50

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Enantiospecific plasma concentrations of racemic ketoprofen after oral and intramuscular administration in growing pigs

Mustonen, K., Niemi, A., Raekallio, M., Heinonen, M., Peltoniemi, O. A. T., Palviainen, M., Siven, M., Peltoniemi, M. & Vainio, O., 2012, In : Acta Veterinaria Scandinavica. 54, 8 p., 55.

Research output: Contribution to journalArticleScientificpeer-review

2010

Computational prediction of local drug effect on carcinogenic acetaldehyde in the mouth based on in vitro/in vivo results of freely soluble L-cysteine

Kartal, A., Marvola, J., Matheka, J., Peltoniemi, M. & Siven, M., 2010, In : Drug Development and Industrial Pharmacy. 36, 6, p. 715-723 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Early detection of ketoprofen-induced acute kidney injury in sheep as determined by evaluation of urinary enzyme activities

Raekallio, M., Saario-Paunio, E., Rajamäki, M. M., Sankari, S. M., Siven, M. S., Palviainen, M., Peltoniemi, M., Leinonen, M-E., Honkavaara, M. J. & Vainio, O., Oct 2010, In : American Journal of Veterinary Research. 71, 10, p. 1246-1252 7 p.

Research output: Contribution to journalArticleScientificpeer-review

2008

Compatibility of chewing gum excipients with the amino acid L-cysteine and stability of the active substance in directly compressed chewing gum formulation

Kartal, A., Björkqvist, M., Lehto, V-P., Juppo, A. M., Marvola, M. & Siven, M., 2008, In : Journal of Pharmacy and Pharmacology. 60, 9, p. 1131-1138 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Evaluation of bioequivalence after oral, intramuscular, and intravenous administration of racemic ketoprofen in pigs

Raekallio, M., Mustonen, K. M., Heinonen, M., Peltoniemi, O., Säkkinen, M. S., Peltoniemi, M., Honkavaara, J. & Vainio, O., 2008, In : American Journal of Veterinary Research. 69, 1, p. 108-113 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Paha maku ja sen peittäminen lasten lääkkeissä

Juppo, A. M., Alanko, S., Lähdesmäki, M., Säkkinen, M., Mustonen, S. & Tuorila, H., 2008, In : Dosis : farmaseuttinen aikakauskirja. 24, 1, p. 18-30 13 p.

Research output: Contribution to journalArticleScientificpeer-review

2007

Effects of urine alkalization and activated charcoal on the pharmacokinetics of orally administered carprofen in dogs

Raekallio, M., Honkavaara, M. J., Säkkinen, M. & Peltoniemi, M., 2007, In : American Journal of Veterinary Research. 68, 4, p. 423-427

Research output: Contribution to journalArticleScientificpeer-review

Formulation and in-vivo evaluation of L-cysteine chewing gums for binding carcinogenic acetaldehyde in the saliva during smoking

Kartal, A., Hietala, J., Laakso, I., Kaihovaara, P., Salaspuro, V., Säkkinen, M. S., Salaspuro, M. & Marvola, M., 2007, In : Journal of Pharmacy and Pharmacology. 59, 10, p. 1353-1358

Research output: Contribution to journalArticleScientificpeer-review

2006

Are chitosan formulations mucoadhesive in the human small intestine? An evaluation based on gamma scintigraphy

Säkkinen, M. S., Marvola, J., Kanerva, H., Lindevall, K., Ahonen, A. & Marvola, M., 2006, In : International Journal of Pharmaceutics. 307, 2, p. 285-291 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Farmakokinetiikka ja biofarmasia –opintojakson opetus- ja arviointimenetelmien kehittäminen: Julkaisussa Levander, Heinimo, Ruohisto. toim. Yliopistopedagogiikan perusteet ja Miten opetan verkossa –koulutukset Viikin kampuksella: Kokemukset ja vaikuttavuuden arviointia

Translated title of the contribution: Development of education in biopharmaceuticsSiven, M. S., 2006, (Viikin opetuksen kehittäispalvelut Julkaisuja 3/2006)

Research output: Book/ReportCommissioned report

Open Access

Ketoprofen pharmacokinetics in the sheep - Investigations on the effect of drug overdose on renal function

Säkkinen, M., Halsas, M., Saario, E., Honkavaara, M. J., Raekallio, M. & Vainio, O., 2006, In : European Journal of Pharmaceutical Sciences. 28, suppl, p. 33

Research output: Contribution to journalConference articleProfessional

2005

Are chitosan granules mucoadhesive in the human stomach - a gamma scintigraphic study in man.

Säkkinen, M., Marvola, J. & Marvola, M., 2005, Proceedings of the 1st BBBB Conference on Pharmaceutical Sciences. p. 224

Research output: Chapter in Book/Report/Conference proceedingConference contributionProfessional

Vuorovaikutteinen opetus äänestysjärjestelmää käyttäen

Heinimo, S-M., Lehtonen, U., Säkkinen, M. & Raasmaja, A., 2005, In : Peda-Forum. 12, 2, p. 7-9 3 p.

Research output: Contribution to journalArticleProfessional

2004

Gamma scintigraphic evaluation of the fate of microcrystalline chitosan granules in human stomach

Säkkinen, M. S., Marvola, J. A., Kanerva, H., Lindevall, K., Kekki, T., Ahonen, A. & Marvola, M. L. A., 2004, In : European Journal of Pharmaceutics and Biopharmaceutics. 57, p. 133-143

Research output: Contribution to journalArticleScientificpeer-review

Scintigraphic verification of adherence of a chitosan formulation to the human oesophagus

Säkkinen, M. S., Marvola, J. A., Kanerva, H., Lindevall, K., Ahonen, A. & Marvola, M. L. A., 2004, In : European Journal of Pharmaceutics and Biopharmaceutics. 57, p. 145-147

Research output: Contribution to journalArticleScientificpeer-review

Evaluation of microcrystalline chitosans for gastro-retentive drug delivery

Säkkinen, M. S., Tuononen, T., Jurjenson, H., Veski, P. & Marvola, M. L. A., 2003, In : European Journal of Pharmaceutical Sciences. 19, p. 345-353

Research output: Contribution to journalArticleScientificpeer-review

In vivo evaluation of matrix granules containing microcrystalline chitosan as a gel-forming excipient

Säkkinen, M. S., Linna, A., Ojala, S., Jurjenson, H., Veski, P. & Marvola, M. L. A., 2003, In : International Journal of Pharmaceutics. 250, p. 227-237

Research output: Contribution to journalArticleScientificpeer-review

2002

In vitro evaluation of microcrystalline chitosan (MCCh) as gel-forming excipient in matrix granules

Säkkinen, M. S., Seppälä, U., Heinänen, P. & Marvola, M. L. A., 2002, In : European Journal of Pharmaceutics and Biopharmaceutics. 54, p. 33-40

Research output: Contribution to journalArticleScientificpeer-review

2001

Kitosaani farmaseuttisena apuaineena peroraalisissa säätövalmisteissa

Translated title of the contribution: Chitosan as excipient in controlled release drug delivery systems for peroral drug administrationSiven, M. S., 2001, In : Dosis : farmaseuttinen aikakauskirja. 17, 2, p. 117-126

Research output: Contribution to journalReview ArticleScientificpeer-review

2000

In vitro evaluation of microcrystalline chitosan and its characteristics as a release rate modifying excipient

Siven, M. S., 2000, Proceedings of the 3rd World Meeting APV/APGI. p. 41-42

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

1999

Organic acids as excipients in matrix granules for colon-specific drug delivery

Nykänen, P., Krogars, K., Säkkinen, M. S., Heinämäki, J. T., Jurjensson, H., Veski, P. & Marvola, M. L. A., 1999, In : International Journal of Pharmaceutics. 184, p. 251-261

Research output: Contribution to journalArticleScientificpeer-review