Photo of Michael Wrzaczek
  • PL 65 (Viikinkaari 1)



  • Viikinkaari 1, Biocentre 3

    00790 Helsinki



Research output per year

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Personal profile

Description of research and teaching

The main research focus of my group is to understand the molecular foundation of how receptor-like kinases (RLKs) are integrated with reactive oxygen species (ROS)-mediated signaling. On a physiological level we investigate how RLKs and ROS function in stress adaptation and plant development. Starting from the regulation of ROS-induced cell death we aim to understand also other aspects of ROS signaling, such as plant development.
We analyze the function of receptor-like protein kinases in ROS sensing. In particular the CYSTEINE-RICH RECEPTOR-LIKE KINASES (CRKs) are interesting proteins with a novel lectin-like ectodomains structure. In higher plants this protein family has undergone drastic expansions. Aleksia Vaattovaara is collaborating with Dr. Jarkko Salojärvi to understand the complex evolution of the CRKs and related proteins families address the reasons for the differential expansion of the CRKs in different plant families. Dr. Sachie Kimura is interested in how CRKs participate in control of extracellular ROS production and the coordination of systemic signaling in plants. Kerri Hunter is aiming to understand cell biological aspects of CRK function and to identify the protein complexes harboring CRKs.
Besides research projects I am interested in Unix, Linux/BSD and Perl-scripting and introduce biologists to those computer tools. I have been teaching programming for biologists for several years at the University of Helsinki. Currently I am teaching plant biochemistry and cell biology as well as plant genome evolution.

Education information

Docent, University of Helsinki, Finland, 2011

Education information

PhD, University of Vienna, Austria, 2004

Education information

Master of Science, University of Vienna, Austria, 2001

Fields of Science

  • 118 Biological sciences
  • Plant biology
  • Plant biochemistry
  • Reactive oxygen species
  • Programmed cell death
  • Signal perception
  • 1183 Plant biology, microbiology, virology
  • 1182 Biochemistry, cell and molecular biology

International and National Collaboration Publications and projects within past five years.


CRK2 and C-terminal Phosphorylation of NADPH Oxidase RBOHD Regulate Reactive Oxygen Species Production in Arabidopsis

Kimura, S., Hunter, K., Vaahtera, L., Tran, C., Citterico, M., Vaattovaara, A., Rokka, A., Stolze, S. C., Harzen, A., Meißner, L., Wilneks, M. M. T., Hamann, T., Toyoga, M., Nakagami, H. & Wrzaczek, M., 8 Apr 2020, In : Plant Cell. 32, 4, p. 1063–1080 18 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Arabidopsis RCD1 coordinates chloroplast and mitochondrial functions through interaction with ANAC transcription factors

Shapiguzov, A., Vainonen, J., Hunter, K. A., Tossavainen, H. P. M., Tiwari, A., Järvi, S., Hellman, M. H., Aarabi, F., Alseekh, S., Wybouw, B., Van Der Kelen, K., Nikkanen, L., Krasensky-Wrzaczek, J., Sipari, N. H., Keinänen, M., Tyystjaervi, E., Rintamäki, E., De Rybel, B., Salojärvi, J. T., Van Breusegem, F. & 6 others, Fernie, A. R., Brosche, M. J., Permi, P. E. I., Aro, E-M., Wrzaczek, M. A. & Kangasjärvi, J. S., 15 Feb 2019, In : eLife. 8, 35 p., e43284.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

CRK2 Enhances Salt Tolerance by Regulating Callose Deposition in Connection with PLDα1

Hunter, K., Kimura, S., Rokka, A., Huy Cuong Tran, Toyota, M., Kukkonen, J. P. & Wrzaczek, M., Aug 2019, In : Plant Physiology. 180, 4, p. 2004-2021 18 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Extracellular peptide Kratos restricts cell death during vascular development and stress in Arabidopsis

Escamez, S., Stael, S., Vainonen, J., Willems, P., Jin, H., Kimura, S., Van Breusegem, F., Gevaert, K., Wrzaczek, M. A. & Tuominen, H., 15 Mar 2019, In : Journal of Experimental Botany. 70, 7, p. 2199-2210 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

High-throughput sequencing data and the impact of plant gene annotation quality

Vaattovaara, A. F. M., Leppälä, J. M., Salojärvi, J. T. & Wrzaczek, M. A., 1 Feb 2019, In : Journal of Experimental Botany. 70, 4, p. 1069-1076 8 p., ery43.

Research output: Contribution to journalArticleScientificpeer-review

Open Access


Identification of secreted peptides during tracheary elements differentiation

Wrzaczek, M., Vainonen, J., Stael, S., Tuominen, H., Escamez, S. & Gevaert, K.

01/04/2014 → …

Project: Research project

Viikki Molecular Plant Sciences (VMPS)

Aalto, M., Ahlfors, R., Ainasoja, M. M., Aswathanarayana Reddy, R., Balasubramanian, U., Besseau, S., Blokhina, O., Blomster, T., Brader, G., Broberg, E., Broholm, S., Brosche, M., Campilho, A., Carlsbecker, A., Chenyi, G. G., Davidsson, P., Decourteix, M., Deng, X., Duhazé, C., Kaurilind, E., Ehonen, S., Elomaa, P., Fagerstedt, K., Gauthier, A., He, Q., Helariutta, Y., Helenius, E., Hytönen, T., Idänheimo, N., Jaspers, P., Juntheikki-Palovaara, I., Kangasjärvi, J., Kariola, T., Keceli, A., Kärkönen, A., Kollist, H., Koskela, E., Kujanpää, A., Kukkola, E., Kulichikhin, K., Kurokura, T., Laitinen, R. A. E., Lampio, A., Lehesranta, S. J., Li, J., Li, C., Li, J., Lim, K., Lindgren, O., Mähönen, A. P., Malm, J. U., Marjamaa, K., Minami, A., Mouhu, K., Ng, Y. P., Niemi, O., Nieminen, K., Overmyer, K., Paasela, T., Palva, E. T., Pennanen, V., Piisilä, M., Pöllänen, E. K., Raiskila, S., Rinne, P., Ruokolainen, S., Ruonala, R., Sjöblom, S., Salojärvi, J., Sims-Huopaniemi, K., Takahashi Schmidt, J., Teeri, T., Thitamadee, S., Tähtiharju, S., Törmäkangas, K., Vaahtera, L., Vahala, J., Vahisalu, T., Vainonen, J., van der Schoot, C., Warinowski, T., Welling, A., Virolainen-Arne, E., Wrzaczek, M., Zeng, J. & Zhubing, H.

22/02/2011 → …

Project: Research Evaluation 2011

Understanding peptide ligands and their receptors in plants

Wrzaczek, M.


Project: Research project


RLKs in ROS signaling and vice versa

Michael Wrzaczek (Speaker)
30 Apr 2019

Activity: Talk or presentation typesInvited talk

Plant Cell Walls

Karen Sims-Huopaniemi (Member of organizing committee), Anna Kärkönen (Chair of organizing committee), Michael Alois Wrzaczek (Member of organizing committee), Sari Kristiina Hilden (Member of organizing committee)
18 Feb 201922 Feb 2019

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

King Abdullah University of Science and Technology (KAUST) (External organisation)

Michael Wrzaczek (Board member)
15 May 2019

Activity: Membership typesMembership or other role in review committee

Plant Responses to Climate Change

Karen Sims-Huopaniemi (Member of organizing committee), T Matthew Robson (Chair of organizing committee), Beatriz Fernandez-Marin (Speaker: Keynote), José Ignacio García-Plazaola (Speaker: Keynote), Frauke Pescheck (Speaker: Keynote), Jakub Nezval (Speaker: Keynote), Amarante Vitra (Speaker: Keynote), Eliane Schermer (Speaker: Keynote), Christian Bianchi Stromme (Speaker: Keynote), Alexey Shapiguzov (Speaker: Keynote), Julia Krasensky-Wrzaczek (Scientific Committee Member), Michael Wrzaczek (Speaker: Presenter), Neha Rai (Speaker: Presenter), Mayke Nieuwkerk (Attendee), Adriana Volna (Attendee), Carolina Falcato Fialho Palma (Attendee), Søren G Sommer (Attendee), Giacomo Palai (Attendee), Nikolaj Bjerring Jensen (Attendee), Twinkle Solanki (Attendee), David Israel (Member of organizing committee), Marta Pieriste (Member of organizing committee)
21 Oct 201925 Oct 2019

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

International Conference on Arabidopsis Research 2018

Michael Wrzaczek (Chair of organizing committee)
25 Jun 201829 Jun 2018

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars