Research output per year
Research output per year
Personal profile
Curriculum vitae
My research aims ar unreavelling the cellular and molecular mechanisms by which mechanical signals are transmitted into the nucleus to control stem cell fate. My research integrates cell and molecular biology of genome regulation, biophysics and engineering to address how forces are sensed at the nuclear envelope and transmitted to chromatin to influence gene expression and thus, stem cell fate.
Education/Academic qualification
Structural Engineering, Ph.D., Politecnico di Milano
1 Oct 2011 → 30 Sep 2014
Award Date: 26 Jan 2015
External positions
Guest Scientist, Max Planck institute for Biology and aging
1 Jul 2018 → …Fields of Science
- 1182 Biochemistry, cell and molecular biology
- biomechanics
- mechanobiology
- nuclear mechanics
- 217 Medical engineering
- biomedical engineering
- computational mechanics
International and National Collaboration
Publications and projects within past five years.
Publications
- 1 Article
-
Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage
Nava, M. M., Miroshnikova, Y. A., Biggs, L. C., Whitefield, D. B., Metge, F., Boucas, J., Vihinen, H., Jokitalo, E., Li, X., García Arcos, J. M., Hoffmann, B., Merkel, R., Niessen, C. M., Dahl, K. N. & Wickström, S. A., 14 May 2020, In : Cell. 181, 4, p. 800-+ 40 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile