Miina Ollikainen

Docent in Epigenetics

Academy Research Fellow, Institute for Molecular Medicine Finland
Epigenetics of Complex Diseases and Traits

https://orcid.org/0000-0003-3661-7400

Phone+358504151276, +358294127542
Emailmiina.ollikainen@helsinki.fi

PL 20 (Tukholmankatu 8 B)
00014
Finland

Research output per year

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Personal profile

Description of research and teaching

Miina is an internationally recognized researcher in twin epigenetics, and she has contributed to several important discoveries on the roles of genome and epigenome on both early life and adult complex disease and trait variation.

Since 2013 Miina has led a research group of Epigenetics of Complex Diseases &Traits focusing in obesity, aging, and substance use in early life and in adulthood, using trait-discordant and concordant twin pairs and twin modelling.

Miina is interested in understanding the roles of genome, epigenome and environment in health and disease, in producing reliable biomarker signatures and potential intervention targets for common diseases as well as in identification of epigenetic variants which could be used in risk prediction.

External positions

Postdoctoral Research Fellow, Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne

1 Aug 2007 → 31 Aug 2010

Fields of Science

1184 Genetics, developmental biology, physiology
Epigenetics
Public health
Twin study
substance use
obesity

International and National Collaboration

Publications and projects within past five years.

45 Article
2 Chapter
2 Review Article
1 Doctoral Thesis

An integrative machine learning approach to discovering multi-level molecular mechanisms of obesity using data from monozygotic twin pairs
Kibble, M., Khan, S. A., Ammad-ud-din, M., Bollepalli, S., Palviainen, T., Kaprio, J., Pietiläinen, K. H. & Ollikainen, M., 21 Oct 2020, In : Royal Society Open Science. 7, 10, 21 p., 200872.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
Associations of Alcohol Consumption With Epigenome-Wide DNA Methylation and Epigenetic Age Acceleration: Individual-Level and Co-twin Comparison Analyses
Stephenson, M., Bollepalli, S., Cazaly, E., Salvatore, J. E., Barr, P., Rose, R. J., Dick, D., Kaprio, J. & Ollikainen, M., 30 Dec 2020, In : Alcoholism: Clinical and Experimental Research. 11 p.
Research output: Contribution to journal › Article › Scientific › peer-review
Identification, Heritability, and Relation With Gene Expression of Novel DNA Methylation Loci for Blood Pressure
Huang, Y., Ollikainen, M., Muniandy, M., Zhang, T., van Dongen, J., Hao, G., van Der Most, P. J., Pan, Y., Pervjakova, N., Sun, Y., Hui, Q., Lahti, J., Fraszczyk, E., Lu, X., Sun, D., Richard, M. A., Willemsen, G., Heikkila, K., Leach, I. M., Mononen, N. & 32 others, Kähönen, M., Hurme, M. A., Raitakari, O. T., Drake, A. J., Perola, M., Nuotio, M-L., Huang, Y., Khulan, B., Räikkönen, K., Wolffenbuttel, B. H. R., Zhernakova, A., Fu, J., Zhu, H., Dong, Y., van Vliet-Ostaptchouk, J. V., Franke, L., Eriksson, J. G., Fornage, M., Milani, L., Lehtimäki, T., Vaccarino, V., Boomsma, D., van Der Harst, P., de Geus, E. J. C., Salomaa, V., Li, S., Chen, W., Su, S., Wilson, J., Snieder, H., Kaprio, J. & Wang, X., Jul 2020, In : Hypertension. 76, 1, p. 195-205 11 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Accuracy of self-reported anthropometric measures - Findings from the Finnish Twin Study
Tuomela, J., Kaprio, J., Sipilä, P. N., Silventoinen, K., Wang, X., Ollikainen, M. & Piirtola, M., 2019, In : Obesity Research & Clinical Practice. 13, 6, p. 522-528 7 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Epigenome-wide association study of lung function level and its change
Imboden, M., Wielscher, M., Rezwan, F. I., Amaral, A. F. S., Schaffner, E., Jeong, A., Beckmeyer-Borowko, A., Harris, S. E., Starr, J. M., Deary, I. J., Flexeder, C., Waldenberger, M., Peters, A., Schulz, H., Chen, S., Sunny, S. K., Karmaus, W. J. J., Jiang, Y., Erhart, G., Kronenberg, F. & 19 others, Arathimos, R., Sharp, G. C., Henderson, A. J., Fu, Y., Piirilä, P., Pietiläinen, K. H., Ollikainen, M., Johansson, A., Gyllensten, U., de Vries, M., van der Plaat, D. A., de Jong, K., Boezen, H. M., Hall, I. P., Tobin, M. D., Jarvelin, M-R., Holloway, J. W., Jarvis, D. & Probst-Hensch, N. M., 1 Jul 2019, In : European Respiratory Journal. 54, 1, 18 p., 1900457.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File

1 Not started
4 Finished
6 Active

Mitochondrial biogenesis, epigenetics & obesity
Ollikainen, M., Lundgren, S. N., Pietiläinen, K. & Pirinen, E.
01/09/2019 → …
Project: Research project
Applying novel computational methods and multiple data types to derive new hypotheses into the molecular mechanisms behind obesity
Kibble, M. M., Ollikainen, M., Bollepalli, S., Khan, S. A., Ammad-ud-din, M. & Pietiläinen, K.
01/01/2017 → …
Project: Research project
Substance use epigenetics
Ollikainen, M., Loukola, A., Gupta, R., Bollepalli, S., Kaprio, J., Korhonen, T., Cazaly, E., Salvatore, J. E., Stephenson, M. & Anders, S.
01/01/2017 → …
Project: Research project
Using epigenetic alterations in monozygotic twins to predict the development of metabolic syndrome
Kibble, M. M., Ollikainen, M., Bollepalli, S. & Fu, Y.
01/01/2017 → …
Project: Research project
Epigenetic pathways to obesity
Bollepalli, S., Kibble, M. M., Muniandy, M., Lundgren, S. N. & Ollikainen, M.
01/09/2016 → 31/08/2021
Project: Research project

17 Organisation and participation in conferences, workshops, courses, seminars
5 Peer review of manuscripts
5 Supervisor or co-supervisor of doctoral thesis
2 Invited talk
More
- 1 Academic visit to other institution

Epigenetic biomarkers & potential risk predictors for complex traits
Miina Ollikainen (Speaker)
31 Oct 2019
Activity: Talk or presentation types › Invited talk
Epigenetiikka, elintavat ja sairaudet
Miina Ollikainen (Speaker)
26 Nov 2019
Activity: Talk or presentation types › Invited talk
Epigenomics of Common Diseases
Miina Ollikainen (Attendee)
6 Nov 2019 → 8 Nov 2019
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Keystone Epigenetics and Human Disease
Miina Ollikainen (Attendee)
17 Mar 2019 → 21 Mar 2019
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Building Bridges Autumn 2017: Epigenetics in Clinical and Translational Research
Miina Ollikainen (Member of organizing committee)
10 Oct 2017 → 11 Oct 2017
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars