Research output per year
Research output per year
Personal profile
Description of research and teaching
Miina is an internationally recognized researcher in twin epigenetics, and she has contributed to several important discoveries on the roles of genome and epigenome on both early life and adult complex disease and trait variation.
Since 2013 Miina has led a research group of Epigenetics of Complex Diseases &Traits focusing in obesity, aging, and substance use in early life and in adulthood, using trait-discordant and concordant twin pairs and twin modelling.
Miina is interested in understanding the roles of genome, epigenome and environment in health and disease, in producing reliable biomarker signatures and potential intervention targets for common diseases as well as in identification of epigenetic variants which could be used in risk prediction.
External positions
Postdoctoral Research Fellow, Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne
1 Aug 2007 → 31 Aug 2010
Fields of Science
- 1184 Genetics, developmental biology, physiology
- Epigenetics
- Public health
- Twin study
- substance use
- obesity
International and National Collaboration
Publications and projects within past five years.
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Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study
Lapatto, H. A. K., Kuusela, M., Heikkinen, A., Muniandy, M., van der Kolk, B. W., Gopalakrishnan, S., Pöllänen, N., Sandvik, M., Schmidt, M. S., Heinonen, S., Saari, S., Kuula, J., Hakkarainen, A., Tampio, J., Saarinen, T., Taskinen, M-R., Lundbom, N., Groop, P-H., Tiirola, M., Katajisto, P., & 7 others, 13 Jan 2023, In: Science Advances. 9, 2, 24 p., eadd5163.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
BMI is positively associated with accelerated epigenetic aging in twin pairs discordant for body mass index
Lundgren, S., Kuitunen, S., Pietiläinen, K. H., Hurme, M., Kähönen, M., Männistö, S., Perola, M., Lehtimäki, T., Raitakari, O., Kaprio, J. & Ollikainen, M., Oct 2022, In: Journal of Internal Medicine. 292, 4, p. 627-640 14 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders
Auvinen, P., Vehviläinen, J., Marjonen, H., Modhukur, V., Sokka, J., Wallén, E., Rämö, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. & Kaminen-Ahola, N., 30 Dec 2022, In: BMC Medicine. 20, 1, 495.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Differences in DNA Methylation-Based Age Prediction Within Twin Pairs Discordant for Cancer
Bode, H. F., Heikkinen, A., Lundgren, S., Kaprio, J. & Ollikainen, M., Oct 2022, In: Twin Research and Human Genetics. 25, p. 171-179 9 p., 1832427422000329.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Do Epigenetic Clocks Provide Explanations for Sex Differences in Life Span? A Cross-Sectional Twin Study
Kankaanpää, A., Tolvanen, A., Saikkonen, P., Heikkinen, A., Laakkonen, E. K., Kaprio, J., Ollikainen, M. & Sillanpää, E., 2022, In: Journals of Gerontology. Series A: Biological Sciences and Medical Sciences. 77, 9, p. 1898–1906 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
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Mitochondrial biogenesis, epigenetics & obesity
Ollikainen, M., Lundgren, S. N., Pietiläinen, K. & Pirinen, E.
01/09/2019 → …
Project: Research project
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Substance use epigenetics
Ollikainen, M., Loukola, A., Gupta, R., Bollepalli, S., Kaprio, J., Korhonen, T., Cazaly, E., Salvatore, J. E., Stephenson, M. & Anders, S.
01/01/2017 → …
Project: Research project
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Using epigenetic alterations in monozygotic twins to predict the development of metabolic syndrome
Kibble, M. M., Ollikainen, M., Bollepalli, S. & Fu, Y.
01/01/2017 → …
Project: Research project
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Applying novel computational methods and multiple data types to derive new hypotheses into the molecular mechanisms behind obesity
Kibble, M. M., Ollikainen, M., Bollepalli, S., Khan, S. A., Ammad-ud-din, M. & Pietiläinen, K.
01/01/2017 → …
Project: Research project
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Activities
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Keystone Epigenetics and Human Disease
Miina Ollikainen (Attendee)
17 Mar 2019 → 21 Mar 2019Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Epigenetic biomarkers & potential risk predictors for complex traits
Miina Ollikainen (Speaker)
31 Oct 2019Activity: Talk or presentation types › Invited talk
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Epigenetiikka, elintavat ja sairaudet
Miina Ollikainen (Speaker)
26 Nov 2019Activity: Talk or presentation types › Invited talk
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Epigenomics of Common Diseases
Miina Ollikainen (Attendee)
6 Nov 2019 → 8 Nov 2019Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Epigenomics of Common Diseases 2017
Miina Ollikainen (Attendee)
14 Nov 2017 → 17 Nov 2017Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars