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Publications 2002 2019

2019

Airway hyperresponsiveness in young children with respiratory symptoms A five-year follow-up

Kalliola, S., Malmberg, L. P., Malmstrom, K., Pelkonen, A. S. & Mäkelä, M. J., May 2019, In : Annals of Allergy, Asthma, & Immunology. 122, 5, p. 492-497 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Essential Medicines at the National Level: The Global Asthma Network's Essential Asthma Medicines Survey 2014

Bissell, K., Ellwood, P., Ellwood, E., Chiang, C-Y., Marks, G. B., El Sony, A., Asher, I., Billo, N., Perrin, C., Global Asthma Network Study Grp & Mäkelä, M., 2 Feb 2019, In : International Journal of Environmental Research and Public Health. 16, 4, 15 p., 605.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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High-Dose Vitamin D Supplementation Does Not Prevent Allergic Sensitization of Infants

Rosendahl, J., Pelkonen, A. S., Helve, O., Hauta-alus, H., Holmlund-Suila, E., Valkama, S., Enlund-Cerullo, M., Viljakainen, H., Hytinantti, T., Mäkitie, O., Andersson, S. & Mäkelä, M. J., Jun 2019, In : The Journal of Pediatrics. 209, p. 139-+ 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Tidal breathing flow volume profiles during sleep in wheezing infants measured by impedance pneumography

Gracia-Tabuenca, J., Seppä, V-P., Jauhiainen, M., Kotaniemi-Syrjänen, A., Malmström, K., Pelkonen, A., Mäkelä, M., Viik, J. & Malmberg, L. P., May 2019, In : Journal of Applied Physiology. 126, 5, p. 1409-1418 10 p.

Research output: Contribution to journalArticleScientificpeer-review

2018

Abnormal lung function at preschool age – asthma in adolescence?

Lajunen, K., Kalliola, S., Kotaniemi-Syrjänen, A., Sarna, S., Malmberg, L. P., Pelkonen, A. S. & Mäkelä, M. J., May 2018, In : Annals of Allergy, Asthma, & Immunology. 120, 5, p. 520-526 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Astma ja allergia lievenevät Suomessa - apteekkien allergiabarometri 2010-2016

Jantunen, J., Haahtela, T., Salimäki, J., Pelkonen, A., Mäkelä, M. & Kauppi, P., 2018, In : Suomen lääkärilehti. 73, 6, p. 367-371 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Component-resolved diagnosis in selecting patients for yellowjacket venom immunotherapy

Kukkonen, A. K., Pelkonen, A. S., Edelman, S. M., Kauppi, P. M. & Mäkelä, M. J., Feb 2018, In : Annals of Allergy, Asthma, & Immunology. 120, 2, p. 184-189 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Component-resolved diagnostics demonstrates that most peanut-allergic individuals could potentially introduce tree nuts to their diet

Uotila, R., Kukkonen, A. K., Blom, W. M., Remington, B., Westerhout, J., Pelkonen, A. S. & Makela, M. J., Jun 2018, In : Clinical and Experimental Allergy. 48, 6, p. 712-721 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

EAACI Guidelines on allergen immunotherapy: IgE-mediated food allergy

EAACI Allergen Immunotherapy Guide, Apr 2018, In : Allergy : European journal of allergy and clinical immunology. 73, 4, p. 799-815 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Gal d 1-specific IgE predicts allergy to heated egg in Finnish children

Palosuo, K., Kukkonen, A. K., Pelkonen, A. S. & Makela, M. J., Sep 2018, In : Pediatric Allergy and Immunology. 29, 6, p. 637-643 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Gastrointestinal Symptoms of Food Challenge-proven Non-IgE Cow's Milk Allergy Are Dissipated by Early School Age

Helin, N., Kolho, K-L., Qvist, E., Mäkelä, M. & Merras-Salmio, L., Apr 2018, In : Journal of Pediatric Gastroenterology and Nutrition. 66, 4, p. 598-602 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Health care resource utilization and characteristics of patients with eosinophilic asthma in secondary health care in Finland

Mäkelä, M. J., Christensen, H. N., Karlsson, A., Rastogi, S. & Kettunen, K., 15 Apr 2018, In : European Clinical Respiratory Journal . 5, 8 p., 1458560.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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High arachis hypogaea allergen 2 immunoglobulin E levels predict responses to exposure to a small amount of peanut protein

Burman, J., Kukkonen, A. K., Pelkonen, A. S. & Makela, M. J., Dec 2018, In : Acta Paediatrica. 107, 12, p. 2216-2216 1 p.

Research output: Contribution to journalEditorialScientific

Immunotherapy With the SQ Tree SLIT-tablet in Adults and Adolescents With Allergic Rhinoconjunctivitis

Makela, M. J., Gyllfors, P., Valovirta, E., Steffensen, M. A., Gronager, P. M., Savolainen, J. & Winther, L., Apr 2018, In : Clinical Therapeutics. 40, 4, p. 574-586 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Lapsen rinosinuiitti

Toppila-Salmi, S., Rihkanen, H., Mäkelä, M. & Klockars, T., 2018, In : Duodecim. 134, 8, p. 809-815 7 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Let's get cracking : nut allergy diagnostics and peanut oral immunotherapy

Uotila, R., 2018, Helsinki: Helsingin yliopisto. 93 p.

Research output: ThesisDoctoral ThesisCollection of Articles

Monocytes accumulate in the airways of children with fatal asthma

Eguiluz-Gracia, I., Malmström, K., Dheyauldeen, S. A., Lohi, J., Sajantila, A., Aalokken, R., Sundaram, A. Y. M., Gilfillan, G. D., Makela, M., Baekkevold, E. S. & Jahnsen, F. L., Dec 2018, In : Clinical and Experimental Allergy. 48, 12, p. 1631-1639 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Näin tutkin, hoidan ja seuraan lasten astmaa

Mäkelä, M., Malmberg, P. & Pelkonen, A., 2018, In : Suomen lääkärilehti. 73, 6, p. 342-348 7 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Nocturnal Heart Rate Variability Spectrum Characterization in Preschool Children With Asthmatic Symptoms

Milagro, J., Gil, E., Lazaro, J., Seppä, V-P., Malmberg, L. P., Pelkonen, A. S., Kotaniemi-Syrjänen, A., Makela, M. J., Viik, J. & Bailon, R., Sep 2018, In : IEEE Journal of Biomedical and Health Informatics. 22, 5, p. 1332-1340 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Nonlinear Dynamics of Heart Rate Variability in Children with Asthmatic Symptoms

Milagro, J., Gill, E., Bolea, J., Seppä, V-P., Malmberg, L. P., Pelkonen, A. S., Kotaniemi-Syrjänen, A., Mäkelä, M. J., Viik, J. & Bailon, R., 2018, EMBEC & NBC 2017. Eskola, H., Väisänen, O., Viik, J. & Hyttinen, J. (eds.). SPRINGER-VERLAG SINGAPORE PTE LTD, p. 815-818 4 p. (IFMBE Proceedings; vol. 65).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Nonlinear Local Projection Filter for Impedance Pneumography

Gracia, J., Seppä, V-P., Pelkonen, A., Kotaniemi-Syrjänen, A., Mäkelä, M., Malmberg, P. & Viik, J., 2018, EMBEC & NBC 2017. Eskola, H., Väisänen, O., Viik, J. & Hyttinen, J. (eds.). SPRINGER-VERLAG SINGAPORE PTE LTD, p. 306-309 4 p. (IFMBE Proceedings; vol. 65).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Primary Prevention of Airway Allergy

Wikstén, J., Toppila-Salmi, S. & Mäkelä, M., 5 Nov 2018, In : Current treatment options in allergy. 5, 4, p. 347–355 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Small airway function in children with mild to moderate asthmatic symptoms

Knihtilä, H., Kotaniemi-Syrjänen, A., Pelkonen, A. S., Mäkelä, M. J. & Malmberg, L. P., Oct 2018, In : Annals of Allergy, Asthma, & Immunology. 121, 4, p. 451-457 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Standardizing dose in dosimetric bronchial challenge tests

Malmberg, L. P., Kauppi, P. & Mäkelä, M. J., Sep 2018, In : Clinical Physiology and Functional Imaging. 38, 5, p. 903-906 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Wheat oral immunotherapy was moderately successful but was associated with very frequent adverse events in children aged 6-18 years

Kulmala, P., Pelkonen, A. S., Kuitunen, M., Paassilta, M., Remes, S., Schultz, R., Dunder, T., Turunen, S. & Makela, M. J., May 2018, In : Acta Paediatrica. 107, 5, p. 861-870 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2017

Age-related off-label use of nasal corticosteroids for allergies is relatively common in Finnish children with asthma

Sonninen, K., Jyrkka, J., Martikainen, J. E., Malmstrom, K., Makela, M. J. & Sepponen, K., Nov 2017, In : Acta Paediatrica. 106, 11, p. 1830-1836 7 p.

Research output: Contribution to journalArticleScientificpeer-review

A History of Cow's Milk Allergy Is Associated with Lower Vitamin D Status in Schoolchildren

Rosendahl, J., Fogelholm, M., Pelkonen, A., Makela, M. J., Makitie, O. & Erkkola, M., 2017, In : Hormone research in paediatrics. 88, 3-4, p. 244-250 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Allergen immunotherapy for IgE-mediated food allergy: a systematic review and meta-analysis

Nurmatov, U., Dhami, S., Arasi, S., Pajno, G. B., Fernandez-Rivas, M., Muraro, A., Roberts, G., Akdis, C., Alvaro-Lozano, M., Beyer, K., Bindslev-Jensen, C., Burks, W., du Toit, G., Ebisawa, M., Eigenmann, P., Knol, E., Mäkelä, M., Nadeau, K. C., O'Mahony, L., Papadopoulos, N. & 7 othersPoulsen, L. K., Sackesen, C., Sampson, H., Santos, A. F., van Ree, R., Timmermans, F. & Sheikh, A., Aug 2017, In : Allergy : European journal of allergy and clinical immunology. 72, 8, p. 1133-1147 15 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Birth decade affects the sensitization pattern and asthma risk in Finnish adult population

Toppila-Salmi, S., Luukkainen, A., Lemmetyinen, R., Karjalainen, J., Huhtala, H., Renkonen, R., Wang, D. Y., Makela, M. J. & Pekkanen, J., Nov 2017, In : Allergy : European journal of allergy and clinical immunology. 72, 11, p. 1791-1795 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Dual responses of CD14 methylation to distinct environments: a role in asthma and allergy

Song, Y., Khoo, S-K., Lee, K. H., Makela, M., Haahtela, T., LeSouef, P. & Zhang, G. B., 1 Dec 2017, In : European Respiratory Journal. 50, 6, 4 p., 1701228.

Research output: Contribution to journalLetterScientific

Immunohistology and remodeling in fatal pediatric and adolescent asthma

Malmström, K., Lohi, J., Sajantila, A., Jahnsen, F. L., Kajosaari, M., Sarna, S. & Makela, M. J., 16 May 2017, In : Respiratory Research. 18, 9 p., 94.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Lasten astman diagnostiikka ja hoito

Pelkonen, A. & Mäkelä, M., 2017, Lääkärin käsikirja. Jousimaa, J., Alenius, H., Atula, S., Berghem, N., Kattainen, A., Kunnamo, I., Pelttari, H. & Teikari, M. (eds.). 12. uud. p. ed. Helsinki: Duodecim, p. 1285-1289 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Likelihood of Immediate Food Challenge Reactions Varies by Age, History, Allergens, and Levels of Sensitization

Kotaniemi-Syrjänen, A., Csonka, P., Pelkonen, A. & Mäkelä, M., Mar 2017, In : Pediatric allergy immunology and pulmonology. 30, 1, p. 45-52 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Luontoaskel tarttumattomien tulehdustautien torjumiseksi

Haahtela, T., Hanski, I., Von Hertzen, L., Jousilahti, P., Laatikainen, T., Mäkelä, M. J., Puska, P., Reijula, K., Saarinen, K., Vartiainen, E., Vasankari, T. & Virtanen, S., 2017, In : Duodecim. 133, 1, p. 19-26 8 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Measurement of tidal breathing flows in infants using impedance pneumography

Malmberg, L. P., Seppa, V-P., Kotaniemi-Syrjänen, A., Malmström, K., Kajosaari, M., Pelkonen, A. S., Viik, J. & Makela, M. J., Feb 2017, In : European Respiratory Journal. 49, 2, 8 p., 1600926.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes

Anto, J. M., Bousquet, J., Akdis, M., Auffray, C., Keil, T., Momas, I., Postma, D. S., Valenta, R., Wickman, M., Cambon-Thomsen, A., Haahtela, T., Lambrecht, B. N., Carlsen, K. C. L., Koppelman, G. H., Sunyer, J., Zuberbier, T., Annesi-Maesano, I., Arno, A., Bindslev-Jensen, C., De Carlo, G. & 68 othersForastiere, F., Heinrich, J., Kowalski, M. L., Maier, D., Melen, E., Smit, H. A., Standl, M., Wright, J., Asarnoj, A., Benet, M., Ballardini, N., Garcia-Aymerich, J., Gehring, U., Guerra, S., Hohmann, C., Kull, I., Lupinek, C., Pinart, M., Skrindo, I., Westman, M., Smagghe, D., Akdis, C., Andersson, N., Bachert, C., Ballereau, S., Ballester, F., Basagana, X., Bedbrook, A., Bergstrom, A., von Berg, A., Brunekreef, B., Burte, E., Carlsen, K-H., Chatzi, L., Coquet, J. M., Curin, M., Demoly, P., Eller, E., Fantini, M. P., von Hertzen, L., Hovland, V., Jacquemin, B., Just, J., Keller, T., Kiss, R., Kogevinas, M., Koletzko, S., Lau, S., Lehmann, I., Lemonnier, N., Mäkelä, M., Mestres, J., Mowinckel, P., Nadif, R., Nawijn, M. C., Pellet, J., Pin, I., Porta, D., Ranciere, F., Rial-Sebbag, E., Saeys, Y., Schuijs, M. J., Siroux, V., Tischer, C. G., Torrent, M., Varraso, R., Wenzel, K. & Xu, C-J., Feb 2017, In : Journal of Allergy and Clinical Immunology. 139, 2, p. 388-399 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Self-Reported Allergic Rhinitis and/or Allergic Conjunctivitis Associate with IL13 rs20541 Polymorphism in Finnish Adult Asthma Patients

Adjers, K., Luukkainen, A., Pekkanen, J., Hurme, M., Huhtala, H., Renkonen, R., Wang, D. Y., Mäkelä, M. J., Karjalainen, J. & Toppila-Salmi, S., Mar 2017, In : International Archives of Allergy and Immunology. 172, 2, p. 123-128 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Sensitivity of Newly Defined Impulse Oscillometry Indices in Preschool Children

Knihtila, H., Kotaniemi-Syrjänen, A., Pelkonen, A. S., Kalliola, S., Makela, M. J. & Malmberg, L. P., May 2017, In : Pediatric Pulmonology. 52, 5, p. 598-605 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Significant disparities in allergy prevalence and microbiota between the young people in Finnish and Russian Karelia

Ruokolainen, L., Paalanen, L., Karkman, A., Laatikainen, T., von Hertzen, L., Vlasoff, T., Markelova, O., Masyuk, V., Auvinen, P., Paulin, L., Alenius, H., Fyhrquist, N., Hanski, I., Mäkelä, M., Zilber, E., Jousilahti, P., Vartiainen, E. & Haahtela, T., May 2017, In : Clinical and Experimental Allergy. 47, 5, p. 665-674 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Small airway oscillometry indices: Repeatability and bronchodilator responsiveness in young children

Knihtilä, H., Kotaniemi-Syrjanen, A., Pelkonen, A. S., Kalliola, S., Makela, M. J. & Malmberg, L. P., Oct 2017, In : Pediatric Pulmonology. 52, 10, p. 1260-1267 8 p.

Research output: Contribution to journalArticleScientificpeer-review

The Finnish Allergy Programme 2008-2018 works

Haahtela, T., Valovirta, E., Bousquet, J., Mäkelä, M. & Allergy Programme Steering Grp, Jun 2017, In : European Respiratory Journal. 49, 6, 5 p., 1700470.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Vitamin D, high-sensitivity C-reactive protein, and airway hyperresponsiveness in infants with recurrent respiratory symptoms

Määttä, A. M., Kotaniemi-Syrjänen, A., Malmström, K., Malmberg, L. P., Sundvall, J., Pelkonen, A. S. & Makela, M. J., Sep 2017, In : Annals of Allergy, Asthma, & Immunology. 119, 3, p. 227-231 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2016

Aberrant small airways function relates to asthma severity in young children

Kalliola, S., Malmberg, L. P., Pelkonen, A. S. & Makela, M. J., Feb 2016, In : Respiratory Medicine. 111, p. 16-20 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Adult but no pediatric anaphylaxis-related deaths in the Finnish population from 1996 to 2013

Kivisto, J. E., Dunder, T., Protudjer, J. L. P., Karjalainen, J., Huhtala, H. & Makela, M. J., Aug 2016, In : Journal of Allergy and Clinical Immunology. 138, 2, p. 630-632 6 p.

Research output: Contribution to journalArticleScientific

Open Access
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Akuutti astma ja uloshengitysvaikeus

Jartti, T., Mäkelä, M. & Remes, S., 2016, Lastentautien päivystyskirja. Korppi, M., Kröger, L., Rantala, H. & Niinikoski, H. (eds.). 3. uud. p. ed. Helsinki: Duodecim, p. 84-88 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional