20022020

Research output per year

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Publications

2020

Airway hyperresponsiveness, remodeling and inflammation in infants with wheeze

Malmström, K., Lohi, J., Malmberg, L. P., Kotaniemi-Syrjänen, A., Lindahl, H., Sarna, S., Pelkonen, A. S. & Mäkelä, M. J., May 2020, In : Clinical and Experimental Allergy. 50, 5, p. 558-566 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper

Hox, V., Lourijsen, E., Jordens, A., Aasbjerg, K., Agache, I., Alobid, I., Bachert, C., Boussery, K., Campo, P., Fokkens, W., Hellings, P., Hopkins, C., Klimek, L., Makelä, M., Moesges, R., Mullol, J., Pujols, L., Rondon, C., Rudenko, M., Toppila-Salmi, S. & 7 others, Scadding, G., Scheire, S., Tomazic, P-V., Van Zele, T., Wagemann, M., van Boven, J. F. M. & Gevaert, P., 3 Jan 2020, In : Clinical and Translational Allergy. 10, 1, 27 p., 1.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Cut-off values to evaluate exercise-induced asthma in eucapnic voluntary hyperventilation test for children

Burman, J., Elenius, V., Lukkarinen, H., Kuusela, T., Mäkelä, M. J., Kesti, O., Väätäinen, K., Maunula, M., Remes, S. & Jartti, T., 26 Jun 2020, In : Clinical Physiology and Functional Imaging. 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Digital transformation of health and care to sustain Planetary Health: The MASK proof-of-concept for airway diseases-POLLAR symposium under the auspices of Finland's Presidency of the EU, 2019 and MACVIA-France, Global Alliance against Chronic Respiratory Diseases (GARD, WH0) demonstration project, Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Ageing

Bousquet, J., Anto, J. M., Haahtela, T., Jousilahti, P., Erhola, M., Basagana, X., Czarlewski, W., Odemyr, M., Palkonen, S., Sofiev, M., Velasco, C., Bedbrook, A., Delgado, R., Kouznetsov, R., Mäkelä, M., Palamarchuk, Y., Saarinen, K., Tommila, E., Valovirta, E., Vasankari, T. & 12 others, Zuberbier, T., Annesi-Maesano, I., Benveniste, S., Mathieu-Dupas, E., Pepin, J-L., Picard, R., Zeng, S., Ayache, J., Calves Venturos, N., Micheli, Y., Jullian-Desayes, I. & Laune, D., 19 Jun 2020, In : Clinical and Translational Allergy. 10, 1, 9 p., 24.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Early bronchial inflammation and remodeling and airway hyperresponsiveness at school age

Malmberg, L. P., Malmström, K., Kotaniemi-Syrjänen, A., Lohi, J., Pelkonen, A. S., Sarna, S. & Mäkelä, M. J., Jul 2020, In : Allergy : European journal of allergy and clinical immunology. 75, 7, p. 1765-1768 4 p.

Research output: Contribution to journalLetterScientificpeer-review

Efficacy and safety of treatment with biologicals (benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab) for severe eosinophilic asthma

Agache, I., Beltran, J., Akdis, C., Akdis, M., Canelo-Aybar, C., Canonica, W., Casale, T., Chivato, T., Corren, J., Del Giacco, S., Eiwegger, T., Firinu, D., Gern, J. E., Hamelmann, E., Hanania, N., Mäkelä, M., Martín, I. H., Nair, P., O’Mahony, L., Papadopoulos, N. G. & 14 others, Papi, A., Park, H-S., Pérez de Llano, L., Posso, M., Rocha, C., Quirce, S., Sastre, J., Shamji, M., Song, Y., Steiner, C., Schwarze, J., Alonso-Coello, P., Palomares, O. & Jutel, M., May 2020, In : Allergy : European journal of allergy and clinical immunology. 75, 5, p. 1023-1042 20 p.

Research output: Contribution to journalArticleScientificpeer-review

Efficacy and safety of treatment with biologicals (benralizumab, dupilumab and omalizumab) for severe allergic asthma: A systematic review for the EAACI Guidelines - recommendations on the use of biologicals in severe asthma

Agache, I., Rocha, C., Beltran, J., Song, Y., Posso, M., Solà, I., Alonso-Coello, P., Akdis, C., Akdis, M., Canonica, W., Casale, T., Chivato, T., Corren, J., Del Giacco, S., Eiwegger, T., Firinu, D., Gern, J. E., Hamelmann, E., Hanania, N., Mäkelä, M. & 14 others, Martín, I. H., Nair, P., O’Mahony, L., Papadopoulos, N. G., Papi, A., Park, H-S., Pérez de Llano, L., Quirce, S., Sastre, J., Shamji, M., Schwarze, J., Canelo-Aybar, C., Palomares, O. & Jutel, M., May 2020, In : Allergy : European journal of allergy and clinical immunology. 75, 5, p. 1043-1057 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Efficacy and safety of treatment with dupilumab for severe asthma: A systematic review of the EAACI guidelines-Recommendations on the use of biologicals in severe asthma

Agache, I., Song, Y., Rocha, C., Beltran, J., Posso, M., Steiner, C., Alonso-Coello, P., Akdis, C., Akdis, M., Canonica, G. W., Casale, T., Chivato, T., Corren, J., del Giacco, S., Eiwegger, T., Firinu, D., Gern, J. E., Hamelmann, E., Hanania, N., Mäkelä, M. & 14 others, Martin, I. H., Nair, P., O'Mahony, L., Papadopoulos, N. G., Papi, A., Park, H-S., de Llano, L. P., Quirce, S., Sastre, J., Shamji, M., Schwarze, J., Canelo-Aybar, C., Palomares, O. & Jutel, M., May 2020, In : Allergy : European journal of allergy and clinical immunology. 75, 5, p. 1058-1068 11 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Predictive value of childhood airway hyperresponsiveness to indirect stimuli: 10-year longitudinal study

Lajunen, K. T., Malmberg, L. P., Kalliola, S., Kotaniemi-Syrjänen, A., Pelkonen, L. A. S. & Mäkelä, M. J., 27 Jun 2020, In : Pediatric Allergy and Immunology. 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Young children with moderate-to-severe atopic dermatitis can be treated safely and effectively with either topical tacrolimus or mild corticosteroids

Perälä, M., Ahola, M., Mikkola, T., Pelkonen, A. S., Remitz, A. & Mäkelä, M. J., Mar 2020, In : Acta Paediatrica. 109, 3, p. 550-556 7 p.

Research output: Contribution to journalArticleScientificpeer-review

2019

Airway hyperresponsiveness in young children with respiratory symptoms A five-year follow-up

Kalliola, S., Malmberg, L. P., Malmstrom, K., Pelkonen, A. S. & Mäkelä, M. J., May 2019, In : Annals of Allergy, Asthma, & Immunology. 122, 5, p. 492-497 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Children with wheat allergy usually tolerate oats

Burman, J., Palosuo, K., Kukkonen, K., Pelkonen, A. & Makela, M. J., 8 Sep 2019, In : Pediatric Allergy and Immunology. 3 p.

Research output: Contribution to journalLetterScientificpeer-review

Open Access
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Eliciting allergens and treatment of anaphylaxis: Report of the finnish national anaphylaxis registry

Edelman, S. M., Kukkonen, A. K. & Mäkelä, M. J., Oct 2019, In : Allergy : European journal of allergy and clinical immunology. 74, 10, p. 2010-2013 4 p.

Research output: Contribution to journalLetterScientificpeer-review

Open Access
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Epäsuorat altistuskokeet astman diagnosoinnissa

Koskela, H., Tikkakoski, A., Karjalainen, J., Mäkelä, M. & Malmberg, P., 2019, In : Duodecim. 135, 18, p. 1787-1794 8 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Essential Medicines at the National Level: The Global Asthma Network's Essential Asthma Medicines Survey 2014

Bissell, K., Ellwood, P., Ellwood, E., Chiang, C-Y., Marks, G. B., El Sony, A., Asher, I., Billo, N., Perrin, C., Global Asthma Network Study Grp & Mäkelä, M., 2 Feb 2019, In : International Journal of Environmental Research and Public Health. 16, 4, 15 p., 605.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Genetic and environmental susceptibility to food allergy in a registry of twins

Kivisto, J. E., Clarke, A., Dery, A., De Schryver, S., Shand, G., Huhtala, H., Mäkelä, M. J., Asai, Y., Nadeau, K., Harada, L., Chan, E. S. & Ben-Shoshan, M., 2019, In : Journal of allergy and clinical immunology: In practice. 7, 8, p. 2916-2918 3 p.

Research output: Contribution to journalLetterScientific

Open Access
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High-Dose Vitamin D Supplementation Does Not Prevent Allergic Sensitization of Infants

Rosendahl, J., Pelkonen, A. S., Helve, O., Hauta-alus, H., Holmlund-Suila, E., Valkama, S., Enlund-Cerullo, M., Viljakainen, H., Hytinantti, T., Mäkitie, O., Andersson, S. & Mäkelä, M. J., Jun 2019, In : The Journal of Pediatrics. 209, p. 139-+ 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Miten tunnistan eosinofiilisen ruokatorvitulehduksen?

Kauppila, T., Heikkinen, M., Mäkelä, M. & Merras-Salmio, L., 2019, In : Suomen lääkärilehti. 74, 35, p. 1874-1880 7 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Multimorbidity in Asthma, Allergic Conditions and COPD Increase Disease Severity, Drug Use and Costs: The Finnish Pharmacy Survey

Jantunen, J., Haahtela, T., Salimaki, J., Linna, M., Makela, M., Pelkonen, A. & Kauppi, P., 2019, In : International Archives of Allergy and Immunology. 179, 4, p. 273-280 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Outcome of oral immunotherapy for persistent cow's milk allergy from 11 years of experience in Finland

Kauppila, T. K., Paassilta, M., Kukkonen, A. K., Kuitunen, M., Pelkonen, A. S. & Makela, M. J., May 2019, In : Pediatric Allergy and Immunology. 30, 3, p. 356-362 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Peanut oral immunotherapy increases IgG4 to Ara h 1, 2, and 6 but does not affect IgG4 to other allergens

Uotila, R., Kukkonen, A. K., Greco, D., Pelkonen, A. S. & Mäkelä, M. J., Mar 2019, In : Pediatric Allergy and Immunology. 30, 2, p. 248-252 5 p.

Research output: Contribution to journalLetterScientificpeer-review

Open Access
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Pistiäisallergian siedätyshoito on turvallista ja tehokasta

Kauppi, P., Kukkonen, A. K., Alakoskela, J-M., Pelkonen, A., Mäkelä, M. & Liippo, J., 2019, In : Suomen lääkärilehti. 74, 24-31, p. 1571-1575 5 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Serum chitinase-like protein YKL-40 is linked to small airway function in children with asthmatic symptoms

Knihtilä, H., Kotaniemi-Syrjänen, A., Pelkonen, A. S., Savinko, T., Malmberg, L. P. & Mäkelä, M. J., Dec 2019, In : Pediatric Allergy and Immunology. 30, 8, p. 803-809 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Three-dimensional structure of the wheat -amylase Tri a 17, a clinically relevant food allergen

Hofer, G., Wieser, S., Bogdos, M. K., Gattinger, P., Nakamura, R., Ebisawa, M., Mäkelä, M., Papadopoulos, N., Valenta, R. & Keller, W., May 2019, In : Allergy : European journal of allergy and clinical immunology. 74, 5, p. 1009-1013 5 p.

Research output: Contribution to journalLetterScientificpeer-review

Open Access
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Tidal breathing flow volume profiles during sleep in wheezing infants measured by impedance pneumography

Gracia-Tabuenca, J., Seppä, V-P., Jauhiainen, M., Kotaniemi-Syrjänen, A., Malmström, K., Pelkonen, A., Mäkelä, M., Viik, J. & Malmberg, L. P., May 2019, In : Journal of Applied Physiology. 126, 5, p. 1409-1418 10 p.

Research output: Contribution to journalArticleScientificpeer-review

2018

Abnormal lung function at preschool age – asthma in adolescence?

Lajunen, K., Kalliola, S., Kotaniemi-Syrjänen, A., Sarna, S., Malmberg, L. P., Pelkonen, A. S. & Mäkelä, M. J., May 2018, In : Annals of Allergy, Asthma, & Immunology. 120, 5, p. 520-526 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Astma ja allergia lievenevät Suomessa - apteekkien allergiabarometri 2010-2016

Jantunen, J., Haahtela, T., Salimäki, J., Pelkonen, A., Mäkelä, M. & Kauppi, P., 2018, In : Suomen lääkärilehti. 73, 6, p. 367-371 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Component-resolved diagnosis in selecting patients for yellowjacket venom immunotherapy

Kukkonen, A. K., Pelkonen, A. S., Edelman, S. M., Kauppi, P. M. & Mäkelä, M. J., Feb 2018, In : Annals of Allergy, Asthma, & Immunology. 120, 2, p. 184-189 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Component-resolved diagnostics demonstrates that most peanut-allergic individuals could potentially introduce tree nuts to their diet

Uotila, R., Kukkonen, A. K., Blom, W. M., Remington, B., Westerhout, J., Pelkonen, A. S. & Makela, M. J., Jun 2018, In : Clinical and Experimental Allergy. 48, 6, p. 712-721 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

EAACI Guidelines on allergen immunotherapy: IgE-mediated food allergy

EAACI Allergen Immunotherapy Guide, Apr 2018, In : Allergy : European journal of allergy and clinical immunology. 73, 4, p. 799-815 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Gal d 1-specific IgE predicts allergy to heated egg in Finnish children

Palosuo, K., Kukkonen, A. K., Pelkonen, A. S. & Makela, M. J., Sep 2018, In : Pediatric Allergy and Immunology. 29, 6, p. 637-643 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Gastrointestinal Symptoms of Food Challenge-proven Non-IgE Cow's Milk Allergy Are Dissipated by Early School Age

Helin, N., Kolho, K-L., Qvist, E., Mäkelä, M. & Merras-Salmio, L., Apr 2018, In : Journal of Pediatric Gastroenterology and Nutrition. 66, 4, p. 598-602 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Health care resource utilization and characteristics of patients with eosinophilic asthma in secondary health care in Finland

Mäkelä, M. J., Christensen, H. N., Karlsson, A., Rastogi, S. & Kettunen, K., 15 Apr 2018, In : European Clinical Respiratory Journal . 5, 8 p., 1458560.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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High arachis hypogaea allergen 2 immunoglobulin E levels predict responses to exposure to a small amount of peanut protein

Burman, J., Kukkonen, A. K., Pelkonen, A. S. & Makela, M. J., Dec 2018, In : Acta Paediatrica. 107, 12, p. 2216-2216 1 p.

Research output: Contribution to journalEditorialScientific

Open Access
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Immunotherapy With the SQ Tree SLIT-tablet in Adults and Adolescents With Allergic Rhinoconjunctivitis

Makela, M. J., Gyllfors, P., Valovirta, E., Steffensen, M. A., Gronager, P. M., Savolainen, J. & Winther, L., Apr 2018, In : Clinical Therapeutics. 40, 4, p. 574-586 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Lapsen rinosinuiitti

Toppila-Salmi, S., Rihkanen, H., Mäkelä, M. & Klockars, T., 2018, In : Duodecim. 134, 8, p. 809-815 7 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Monocytes accumulate in the airways of children with fatal asthma

Eguiluz-Gracia, I., Malmström, K., Dheyauldeen, S. A., Lohi, J., Sajantila, A., Aalokken, R., Sundaram, A. Y. M., Gilfillan, G. D., Makela, M., Baekkevold, E. S. & Jahnsen, F. L., Dec 2018, In : Clinical and Experimental Allergy. 48, 12, p. 1631-1639 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Näin tutkin, hoidan ja seuraan lasten astmaa

Mäkelä, M., Malmberg, P. & Pelkonen, A., 2018, In : Suomen lääkärilehti. 73, 6, p. 342-348 7 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Nocturnal Heart Rate Variability Spectrum Characterization in Preschool Children With Asthmatic Symptoms

Milagro, J., Gil, E., Lazaro, J., Seppä, V-P., Malmberg, L. P., Pelkonen, A. S., Kotaniemi-Syrjänen, A., Makela, M. J., Viik, J. & Bailon, R., Sep 2018, In : IEEE Journal of Biomedical and Health Informatics. 22, 5, p. 1332-1340 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Nonlinear Dynamics of Heart Rate Variability in Children with Asthmatic Symptoms

Milagro, J., Gill, E., Bolea, J., Seppä, V-P., Malmberg, L. P., Pelkonen, A. S., Kotaniemi-Syrjänen, A., Mäkelä, M. J., Viik, J. & Bailon, R., 2018, EMBEC & NBC 2017. Eskola, H., Väisänen, O., Viik, J. & Hyttinen, J. (eds.). SPRINGER-VERLAG SINGAPORE PTE LTD, p. 815-818 4 p. (IFMBE Proceedings; vol. 65).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Nonlinear Local Projection Filter for Impedance Pneumography

Gracia, J., Seppä, V-P., Pelkonen, A., Kotaniemi-Syrjänen, A., Mäkelä, M., Malmberg, P. & Viik, J., 2018, EMBEC & NBC 2017. Eskola, H., Väisänen, O., Viik, J. & Hyttinen, J. (eds.). SPRINGER-VERLAG SINGAPORE PTE LTD, p. 306-309 4 p. (IFMBE Proceedings; vol. 65).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Primary Prevention of Airway Allergy

Wikstén, J., Toppila-Salmi, S. & Mäkelä, M., 5 Nov 2018, In : Current treatment options in allergy. 5, 4, p. 347–355 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Small airway function in children with mild to moderate asthmatic symptoms

Knihtilä, H., Kotaniemi-Syrjänen, A., Pelkonen, A. S., Mäkelä, M. J. & Malmberg, L. P., Oct 2018, In : Annals of Allergy, Asthma, & Immunology. 121, 4, p. 451-457 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Standardizing dose in dosimetric bronchial challenge tests

Malmberg, L. P., Kauppi, P. & Mäkelä, M. J., Sep 2018, In : Clinical Physiology and Functional Imaging. 38, 5, p. 903-906 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Wheat oral immunotherapy was moderately successful but was associated with very frequent adverse events in children aged 6-18 years

Kulmala, P., Pelkonen, A. S., Kuitunen, M., Paassilta, M., Remes, S., Schultz, R., Dunder, T., Turunen, S. & Makela, M. J., May 2018, In : Acta Paediatrica. 107, 5, p. 861-870 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2017

Age-related off-label use of nasal corticosteroids for allergies is relatively common in Finnish children with asthma

Sonninen, K., Jyrkka, J., Martikainen, J. E., Malmstrom, K., Makela, M. J. & Sepponen, K., Nov 2017, In : Acta Paediatrica. 106, 11, p. 1830-1836 7 p.

Research output: Contribution to journalArticleScientificpeer-review

A History of Cow's Milk Allergy Is Associated with Lower Vitamin D Status in Schoolchildren

Rosendahl, J., Fogelholm, M., Pelkonen, A., Makela, M. J., Makitie, O. & Erkkola, M., 2017, In : Hormone research in paediatrics. 88, 3-4, p. 244-250 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Allergen immunotherapy for IgE-mediated food allergy: a systematic review and meta-analysis

Nurmatov, U., Dhami, S., Arasi, S., Pajno, G. B., Fernandez-Rivas, M., Muraro, A., Roberts, G., Akdis, C., Alvaro-Lozano, M., Beyer, K., Bindslev-Jensen, C., Burks, W., du Toit, G., Ebisawa, M., Eigenmann, P., Knol, E., Mäkelä, M., Nadeau, K. C., O'Mahony, L., Papadopoulos, N. & 7 others, Poulsen, L. K., Sackesen, C., Sampson, H., Santos, A. F., van Ree, R., Timmermans, F. & Sheikh, A., Aug 2017, In : Allergy : European journal of allergy and clinical immunology. 72, 8, p. 1133-1147 15 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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