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  • PL 56 (Viikinkaari 5)

    00014

    Finland

1991 …2019
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Publications 1991 2019

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2019

Diverse and variable virus communities in wild plant populations revealed by metagenomic tools

Susi, H., Filloux, D., Frilander, M. J., Roumagnac, P. & Laine, A-L., 11 Jan 2019, In : PeerJ. 7, 24 p., 6140.

Research output: Contribution to journalArticleScientificpeer-review

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Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing

Viita, T., Kyheroinen, S., Prajapati, B., Virtanen, J., Frilander, M. J., Varjosalo, M. & Vartiainen, M. K., Apr 2019, In : Journal of Cell Science. 132, 8, 16 p., 226852.

Research output: Contribution to journalArticleScientificpeer-review

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2018

Early transcriptional response pathways in Daphnia magna are coordinated in networks of crustacean-specific genes

Orsini, L., Brown, J. B., Solari, O. S., Li, D., He, S., Podicheti, R., Stoiber, M. H., Spanier, K. I., Gilbert, D., Jansen, M., Rusch, D. B., Pfrender, M. E., Colbourne, J. K., Frilander, M. J., Kvist, J., Decaestecker, E., De Schamphelaere, K. A. C. & De Meester, L., Feb 2018, In : Molecular Ecology. 27, 4, p. 886-897 12 p.

Research output: Contribution to journalArticleScientificpeer-review

IntEREst: Intron-exon retention estimator

Oghabian, A., Greco, D. & Frilander, M. J., 11 Apr 2018, In : BMC Bioinformatics. 19, 10 p., 130.

Research output: Contribution to journalArticleScientificpeer-review

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Response to growth hormone in patients with RNPC3 mutations

Martos-Moreno, G. A., Travieso-Suarez, L., Pozo-Roman, J., Munoz-Calvo, M. T., Chowen, J. A., Frilander, M. J., Perez-Jurado, L. A., Hawkins, F. G. & Argente, J., Jul 2018, In : EMBO molecular medicine. 10, 7, 4 p., 9143.

Research output: Contribution to journalArticleScientificpeer-review

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2017

Alternative exon definition events control the choice between nuclear retention and cytoplasmic export of U11/U12-65K mRNA

Verbeeren, J., Verma, B., Niemela, E. H., Yap, K., Makeyev, E. V. & Frilander, M. J., May 2017, In : PLoS Genetics. 13, 5, 28 p., 1006824.

Research output: Contribution to journalArticleScientificpeer-review

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Genome sequences of a capulavirus infecting Plantago lanceolata in the land archipelago of Finland

Susi, H., Laine, A-L., Filloux, D., Kraberger, S., Farkas, K., Bernardo, P., Frilander, M. J., Martin, D. P., Varsani, A. & Roumagnac, P., Jul 2017, In : Archives of Virology. 162, 7, p. 2041-2045 5 p.

Research output: Contribution to journalArticleScientificpeer-review

2016

Complete androgen insensitivity syndrome caused by a deep intronic pseudoexon-activating mutation in the androgen receptor gene

Känsäkoski, J., Jaaskelainen, J., Jaaskelainen, T., Tommiska, J., Saarinen, L., Lehtonen, R., Hautaniemi, S., Frilander, M. J., Palvimo, J. J., Toppari, J. & Raivio, T., 9 Sep 2016, In : Scientific Reports. 6, 7 p., 32819.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Daphnia magna transcriptome by RNA-Seq across 12 environmental stressors

Orsini, L., Gilbert, D., Podicheti, R., Jansen, M., Brown, J. B., Solari, O. S., Spanier, K. I., Colbourne, J. K., Rush, D., Decaestecker, E., Asselman, J., De Schamphelaere, K. A. C., Ebert, D., Haag, C. R., Kvist, J., Laforsch, C., Petrusek, A., Beckerman, A. P., Little, T. J., Chaturvedi, A. & 3 othersPfrender, M. E., De Meester, L. & Frilander, M. J., 2016, In : Scientific data . 3, 160030.

Research output: Contribution to journalArticleScientificpeer-review

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2015

Evolutionarily conserved exon definition interactions with U11 snRNP mediate alternative splicing regulation on U11-48K and U11/U12-65K genes

Niemelä, E., Verbeeren, J., Singha, P., Nurmi, V. & Frilander, M. J., 2 Nov 2015, In : RNA Biology. 12, 11, p. 1256-1264 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Flight-induced changes in gene expression in the Glanville fritillary butterfly

Kvist, J., Mattila, A. L. K., Somervuo, P., Ahola, V., Koskinen, P., Paulin, L., Salmela, L., Fountain, T., Rastas, P., Ruokolainen, A., Taipale, M., Holm, L., Auvinen, P., Lehtonen, R., Frilander, M. J. & Hanski, I., Oct 2015, In : Molecular Ecology. 24, 19, p. 4886-4900 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Temperature- and sex-related effects of serine protease alleles on larval development in the Glanville fritillary butterfly

Ahola, V., Koskinen, P., Wong, S. C., Kvist, J., Paulin, L., Auvinen, P., Saastamoinen, M., Frilander, M. J., Lehtonen, R. & Hanski, I., Dec 2015, In : Journal of Evolutionary Biology. 28, 12, p. 2224-2235 12 p.

Research output: Contribution to journalArticleScientificpeer-review

2014

Defective minor spliceosome mRNA processing results in isolated familial growth hormone deficiency

Argente, J., Flores, R., Gutierrez-Arumi, A., Verma, B., Martos-Moreno, G. A., Cusco, I., Oghabian, A., Chowen, J. A., Frilander, M. J. & Perez-Jurado, L. A. ., Mar 2014, In : EMBO molecular medicine. 6, 3, p. 299-306 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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Global analysis of the nuclear processing of transcripts with unspliced U12-type introns by the exosome

Niemelä, E. H., Oghabian, A., Staals, R. H. J., Greco, D., Pruijn, G. J. M. & Frilander, M. J., 2014, In : Nucleic Acids Research. 42, 11, p. 7358-7369 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera

Ahola, V., Lehtonen, R., Somervuo, P., Salmela, L., Koskinen, P., Rastas, P., Valimaki, N., Paulin, L., Kvist, J., Wahlberg, N., Tanskanen, J., Hornett, E. A., Ferguson, L. C., Luo, S., Cao, Z., de Jong, M. A., Duplouy, A., Smolander, O-P., Vogel, H., McCoy, R. C. & 27 othersQian, K., Wong, S. C., Zhang, Q., Ahmad, F., Haukka, J. K., Joshi, A., Salojarvi, J., Wheat, C. W., Grosse-Wilde, E., Hughes, D., Katainen, R., Pitkanen, E., Ylinen, J., Waterhouse, R. M., Turunen, M., Vaharautio, A., Ojanen, S. P., Schulman, A. H., Taipale, M., Lawson, D., Ukkonen, E., Makinen, V., Goldsmith, M. R., Holm, L., Auvinen, P., Frilander, M. J. & Hanski, I., Sep 2014, In : Nature Communications. 5, 9 p., 4737.

Research output: Contribution to journalArticleScientificpeer-review

Transcriptome Analysis Reveals Signature of Adaptation to Landscape Fragmentation

Somervuo, P., Kvist, J., Ikonen, S., Auvinen, P., Paulin, L., Koskinen, P., Holm, L., Taipale, M., Duplouy, A., Ruokolainen, A., Saarnio, S., Siren, J., Kohonen, J., Corander, J., Frilander, M. J., Ahola, V. & Hanski, I., 2 Jul 2014, In : PLoS One. 9, 7, 12 p., 101467.

Research output: Contribution to journalArticleScientificpeer-review

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Virus-Encapsulated DNA Origami Nanostructures for Cellular Delivery

Mikkilä, J., Eskelinen, A-P., Niemelä, E. H., Linko, V., Frilander, M. J., Törmä, P. & Kostiainen, M. A., Apr 2014, In : Nano Letters. 14, 4, p. 2196-2200 5 p.

Research output: Contribution to journalArticleScientificpeer-review

2013

HnRNPH1/H2, U1 snRNP, and U11 snRNP cooperate to regulate the stability of the U11-48K pre-mRNA

Turunen, J. J., Verma, B., Nyman, T. A. & Frilander, M. J., Mar 2013, In : RNA. 19, 3, p. 380-389 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Identification and Validation of Human Papillomavirus Encoded microRNAs

Qian, K., Pietila, T., Rönty, M. J., Michon, F., Frilander, M. J., Ritari, J., Tarkkanen, J., Paulin, L., Auvinen, P. & Auvinen, E., 30 Jul 2013, In : PLoS One. 8, 7, p. Article Number: e70202 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Temperature treatments during larval development reveal extensive heritable and plastic variation in gene expression and life history traits

Kvist, J., Wheat, C. W., Kallioniemi, E., Saastamoinen, M., Hanski, I. & Frilander, M. J., 2013, In : Molecular Ecology. 22, 3, p. 602-619 18 p.

Research output: Contribution to journalArticleScientificpeer-review

2012

Effects of p27Kip1- and p53-shRNAs on kanamycin damaged mouse cochlea.

Pietola, L., Jero, J., Jalkanen, R., Kinnari, T. J., Jero, O., Frilander, M., Pajusola, K., Salminen, M. & Aarnisalo, A. A., 28 Feb 2012, In : World journal of otorhinolaryngology. 2, 1, p. 1-7 7 p.

Research output: Contribution to journalArticleScientificpeer-review

SNP Design from 454 Sequencing of Podosphaera plantaginis Transcriptome Reveals a Genetically Diverse Pathogen Metapopulation with High Levels of Mixed-Genotype Infection

Tollenaere, C. M. J., Susi, H., Nokso-Koivisto, J. P., Koskinen, P., Tack, A. J. M., Auvinen, P., Paulin, L., Frilander, M., Lehtonen, R. J. & Laine, A-L., 2012, In : PLoS One. 7, 12, p. e52492 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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2011

Functional genomics of life history variation in a butterfly metapopulation

Wheat, C. W., Fescemyer, H. W., Kvist, J., Tas, E., Vera, J. C., Frilander, M. J., Hanski, I. & Marden, J. H., 2011, In : Molecular Ecology. 20, 9, p. 1813-1828 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia

Saarikangas, J., Mattila, P. K., Varjosalo, M., Bovellan, M., Hakanen, J., Calzada-Wack, J., Tost, M., Jennen, L., Rathkolb, B., Hans, W., Horsch, M., Hyvönen, M. E., Perälä, N., Fuchs, H., Gailus-Durner, V., Esposito, I., Wolf, E., de Angelis, M. H., Frilander, M. J., Savilahti, H. & 6 othersSariola, H., Sainio, K., Lehtonen, S., Taipale, J., Salminen, M. & Lappalainen, P., 2011, In : Journal of Cell Science. 124, 8, p. 1245-1255 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Requirement of TFIIH kinase subunit Mat1 for RNA Pol II C-terminal domain Ser5 phosphorylation, transcription and mRNA turnover

Helenius, K., Yang, Y., Tselykh, T. V., Pessa, H. K. J., Frilander, M. J. & Makela, T. P., 2011, In : Nucleic Acids Research. 39, 12, p. 5025-5035 11 p.

Research output: Contribution to journalArticleScientificpeer-review

2010

An Ancient Mechanism for Splicing Control: U11 snRNP as an Activator of Alternative Splicing

Verbeeren, J., Niemelä, E., Turunen, J., Will, C. L., Ravantti, J., Luehrmann, R. & Frilander, M. J., 2010, In : Molecular Cell. 37, 6, p. 821-833 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Gene Expression Profiling of U12-Type Spliceosome Mutant Drosophila Reveals Widespread Changes in Metabolic Pathways

Pessa, H. K. J., Greco, D., Kvist, J., Wahlström, G. M., Heino, T. I., Auvinen, P. & Frilander, M. J., 2010, In : PLoS One. 5, 10, p. e13215 13 p.

Research output: Contribution to journalArticleScientificpeer-review

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Nucleotide Polymorphism at a Gene (Pgi) under Balancing Selection in a Butterfly Metapopulation

Wheat, C. W., Haag, C., Marden, J. H., Hanski, I. & Frilander, M. J., 2010, In : Molecular Biology and Evolution. 27, 2, p. 267-281 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs

Michon, F., Tummers, M., Kyyronen, M., Frilander, M. J. & Thesleff, I., 2010, In : Developmental Biology. 340, p. 355-368 14 p.

Research output: Contribution to journalArticleScientificpeer-review

2009

Fitness differences associated with Pgi SNP genotypes in the Glanville fritillary butterfly (Melitaea cinxia)

Orsini, L., Wheat, C. W., Haag, C., Kvist, J., Frilander, M. J. & Hanski, I., 2009, In : Journal of Evolutionary Biology. 22, 2, p. 367-375 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Kemian Nobel ribosomien rakenteen selvittäjille

Frilander, M. J., 2009, In : Duodecim. 125, 22, p. 2476-2477 2 p.

Research output: Contribution to journalArticleScientific

Tudor staphylococcal nuclease is an evolutionarily conserved component of the programmed cell death degradome

Sundström, J. F., Vaculova, A., Smertenko, A. P., Savenkov, E. I., Golovko, A., Minina, E., Tiwari, B. S., Rodriguez-Nieto, S., Zamyatnin, A. A. J., Välineva, T., Saarikettu, J., Frilander, M. J., Suarez, M. F., Zavialov, A., Ståhl, U., Hussey, P. J., Silvennoinen, O., Sundberg, E., Zhivotovsky, B. & Bozhkov, P. V., 2009, In : Nature Cell Biology. 11, 11, p. 1347-1354 8 p.

Research output: Contribution to journalArticleScientificpeer-review

2008

Bacteriophage Mu integration in yeast and mammalian genomes

Paatero, A. O., Turakainen, H., Happonen, L. J., Olsson, C., Palomäki, T., Pajunen, M. I., Meng, X., Otonkoski, T., Tuuri, T., Berry, C., Malani, N., Frilander, M. J., Bushman, F. & Savilahti, H., 2008, In : Nucleic Acids Research. 36, 22, p. e148 1 p.

Research output: Contribution to journalArticleScientificpeer-review

Minor spliceosome components are predominantly localized in the nucleus

Pessa, H. K. J., Will, C. L., Meng, X., Schneider, C., Watkins, N. J., Perälä, N., Nymark, M., Turunen, J. J., Lührmann, R. & Frilander, M. J., 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 25, p. 8655-8660 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Rapid transcriptome characterization for a nonmodel organism using 454 pyrosequencing

Vera, J. C., Wheat, C. W., Fescemyer, H. W., Frilander, M. J., Crawford, D. L., Hanski, I. & Marden, J. H., 2008, In : Molecular Ecology. 17, 7, p. 1636-1647 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Täpläverkkoperhonen liiti genomiaikaan

Frilander, M. J., 2008, In : Duodecim. 124, 19, p. 2242-2243 2 p.

Research output: Contribution to journalArticleScientific

The U11-48K protein contacts the 5' splice site of U12-type introns and the U11-59K protein

Turunen, J. J., Will, C. L., Grote, M., Luhrmann, R. & Frilander, M. J., 2008, In : Molecular and Cellular Biology. 28, 10, p. 3548-3560 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Weight and nutrition affect pre-mRNA splicing of a muscle gene associated with performance, energetics and life history

Marden, J. H., Fescemyer, H. W., Saastamoinen, M., MacFarland, S. P., Vera, J. C., Frilander, M. J. & Hanski, I., 2008, In : Journal of Experimental Biology. 211, 23, p. 3653-3660 8 p.

Research output: Contribution to journalArticleScientificpeer-review

2007

Transcriptional co-activator protein p100 interacts with snRNP proteins and facilitates the assembly of the spliceosome

Yang, J., Välineva, T., Hong, J., Bu, T., Yao, Z., Jensen, O. N., Frilander, M. J. & Silvennoinen, O., 2007, In : Nucleic Acids Research. 35, 13, p. 4485-4494 10 p.

Research output: Contribution to journalArticleScientificpeer-review

2006

The abundance of the spliceosomal snRNPs is not limiting the splicing of U12-type introns

Pessa, H. K. J., Ruokolainen, A. & Frilander, M. J., 2006, In : RNA. 12, p. 1883-1892 10 p.

Research output: Contribution to journalArticleScientificpeer-review

2005

Proximity of the U12 snRNA with both the 5' splice site and the branch point during early stages of spliceosome assembly

Frilander, M. J. & Meng, X., 2005, In : Molecular and Cellular Biology. 25, 12, p. 4813-4825 13 p.

Research output: Contribution to journalArticleScientificpeer-review

2004

Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila

Schneider, C., Will, C. L., Brosius, J., Frilander, M. J. & Lührmann, R., 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 26, p. 9584-9589 6 p.

Research output: Contribution to journalArticleScientificpeer-review

2002

Nonspecific Nucleoside Triphosphatase P4 of Double-Stranded RNA Bacteriophage f6 Is Required for Single-Stranded RNA Packaging and Transcription

Pirttimaa, M. J., Paatero, A. O., Frilander, M. J. & Bamford, D. H., 2002, In : Journal of Virology. 76, 20, p. 10122-10127 6 p.

Research output: Contribution to journalArticleScientificpeer-review

2001

Dynamic Exchanges of RNA Interactions Leading to Catalytic Core Formation in the U12-Dependent Spliceosome

Frilander, M. & Steitz, J. A., 2001, In : Molecular Cell. 7, 1, p. 217-226. 10 p.

Research output: Contribution to journalArticleScientificpeer-review

1999

Initial recognition of U12-dependent introns requires both U11/5' splice-site and U12/branchpoint interactions

Frilander, M. J. & Steitz, J. A., 1999, In : Genes & Development. 13, p. 851-863 13 p.

Research output: Contribution to journalArticleScientificpeer-review

1995

Differentiation between Minus- and Plus-Strand Synthesis: Polymerase Activity of dsRNA Bacteriophage φ6 in an in Vitro Packaging and Replication System

Van Dijk, A. A., Frilander, M. & Bamford, D. H., 1995, In : Virology. 211, 1, p. 320-323 4 p.

Research output: Contribution to journalArticleScientificpeer-review

The large genome segment of dsRNA bacteriophage φ6 is the key regulator in the in vitro minus and plus strand synthesis

Frilander, M., Poranen, M. & Bamford, D. H., 1995, In : RNA. 1, p. 510-518 9 p.

Research output: Contribution to journalArticleScientificpeer-review

1994

Identification Of The Packaging Regions Within The Genomic RNA Segments Of Bacteriophage φ6

GOTTLIEB, P., QIAO, X. Y., STRASSMAN, J., FRILANDER, M. & MINDICH, L., 1994, In : Virology. 200, p. 42-47 6 p.

Research output: Contribution to journalArticleScientificpeer-review