Photo of Mikko Niemi
  • PL 20 (Tukholmankatu 8 C)

    00014

    Finland

20002019
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Publications 2000 2019

2009

Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin

Keskitalo, J., Pasanen, M. K., Neuvonen, P. J. & Niemi, M., 2009, In : Pharmacogenomics. 10, 10, p. 1617-1624 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect of SLCO1B1 polymorphism on the plasma concentrations of bile acids and bile acid synthesis marker in humans

Xiang, X., Yi, H., Neuvonen, M., Pasanen, M. K., Kalliokoski, A., Backman, J. T., Laitila, J., Neuvonen, P. J. & Niemi, M., 2009, In : Pharmacogenetics and Genomics. 19, 6, p. 447-457 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Farmakogenetiikkaa käytännön lääkärille: [lääkeinfo]

Niemi, M. & Kalliokoski, A., 2009, In : Suomen lääkärilehti. 64, 41, p. 3443-3446 4 p.

Research output: Contribution to journalArticleScientific

Geenimuunnos statiinien aiheuttaman myopatian taustalla: [pääkirjoitus]

Niemi, M., 2009, In : Duodecim. 125, 3, p. 241-243 3 p.

Research output: Contribution to journalArticleScientific

Impact of OATP transporters on pharmacokinetics: [review]

Kalliokoski, A. & Niemi, M., 2009, In : British Journal of Pharmacology. 158, 3, p. 693-705 13 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin

Keskitalo, J., Kurkinen, K., Neuvonen, M., Backman, J. T., Neuvonen, P. J. & Niemi, M., 2009, In : British Journal of Clinical Pharmacology. 68, 2, p. 207-213 7 p.

Research output: Contribution to journalArticleScientificpeer-review

2008

ABCB1 haplotypes differentially affect the pharmacokinetics of the acid and lactone forms of simvastatin and atorvastatin

Keskitalo, J., Kurkinen, K., Neuvonen, P. J. & Niemi, M., 2008, In : Clinical Pharmacology and Therapeutics. 84, 4, p. 457-461 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Characterization of novel CYP2C8 haplotypes and their contribution to paclitaxel and repaglinide metabolism

Rodriguez-Antona, C., Niemi, M., Backman, J. T., Kajosaari, L., Neuvonen, P. J., Robledo, M. & Ingelman-Sundberg, M., 2008, In : Pharmacogenomics Journal. 8, 4, p. 268-277 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Different effects of SLCO1B1 polymorphism on the pharmacokinetics and pharmacodynamics of repaglinide and nateglinide

Kalliokoski, A., Neuvonen, M., Neuvonen, P. J. & Niemi, M., 2008, In : Journal of Clinical Pharmacology. 48, 3, p. 311-321 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Effects of gemfibrozil and atorvastatin on the pharmacokinetics of repaglinide in relation to SLCO1B1 polymorphism

Kalliokoski, A., Backman, J. T., Kurkinen, K., Neuvonen, P. J. & Niemi, M., 2008, In : Clinical Pharmacology and Therapeutics. 84, 4, p. 488-496 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Effects of the SLCO1B1*1B haplotype on the pharmacokinetics and pharmacodynamics of repaglinide and nateglinide

Kalliokoski, A., Backman, J. T., Neuvonen, P. J. & Niemi, M., 2008, In : Pharmacogenetics and Genomics. 18, 11, p. 937-942 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Farmakogeneettinen tieto avuksi yksilöllisten lääkeannosten määritykseen

Ranki-Pesonen, M. & Niemi, M., 2008, In : Duodecim. 124, 11, p. 1269-1271 3 p.

Research output: Contribution to journalArticleScientific

Global analysis of genetic variation in SLCO1B1

Pasanen, M. K., Neuvonen, P. J. & Niemi, M., 2008, In : Pharmacogenomics. 9, 1, p. 19-33 15 p.

Research output: Contribution to journalArticleScientificpeer-review

No significant effect of SLCO1B1 polymorphism on the pharmacokinetics of rosiglitazone and pioglitazone

Kalliokoski, A., Neuvonen, M., Neuvonen, P. J. & Niemi, M., 2008, In : British Journal of Clinical Pharmacology. 65, 1, p. 78-86 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Pharmacogenetics of cyclosporine in children suggests an age-dependent influence of ABCB1 polymorphisms

Fanta, S., Niemi, M., Jönsson, S., Karlsson, M. O., Holmberg, C., Neuvonen, P. J., Hoppu, K. & Backman, J. T., 2008, In : Pharmacogenetics and Genomics. 18, 2, p. 77-90 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin

Neuvonen, P. J., Backman, J. T. & Niemi, M., 2008, In : Clinical Pharmacokinetics. 47, 7, p. 463-474 12 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

The effect of gemfibrozil on repaglinide pharmacokinetics persists for at least 12 h after the dose: evidence for mechanism-based inhibition of CYP2C8 in vivo

Tornio, A., Niemi, M., Neuvonen, M., Laitila, J., Kalliokoski, A., Neuvonen, P. J. & Backman, J. T., 2008, In : Clinical Pharmacology and Therapeutics. 84, 3, p. 403-411 9 p.

Research output: Contribution to journalArticleScientificpeer-review

The effect of SLCO1B1 polymorphism on repaglinide pharmacokinetics persists over a wide dose range

Kalliokoski, A., Neuvonen, M., Neuvonen, P. J. & Niemi, M., 2008, In : British Journal of Clinical Pharmacology. 66, 6, p. 818-825 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Trimethoprim and the CYP2C8*3 allele have opposite effects on the pharmacokinetics of pioglitazone

Tornio, A., Niemi, M., Neuvonen, P. J. & Backman, J. T., 2008, In : Drug Metabolism and Disposition. 36, 1, p. 73-80 8 p.

Research output: Contribution to journalArticleScientificpeer-review

2007

Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin

Pasanen, M. K., Fredrikson, H., Neuvonen, P. J. & Niemi, M., 2007, In : Clinical Pharmacology and Therapeutics. 82, 6, p. 726-733 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Effects of clarithromycin and grapefruit juice on the pharmacokinetics of glibenclamide

Lilja, J., Niemi, M., Fredrikson, H. & Neuvonen, P. J., 2007, In : British Journal of Clinical Pharmacology. 63, 6, p. 732-740 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Influence of drug transporter polymorphisms on pravastatin pharmacokinetics in humans

Kivistö, K. T. & Niemi, M., 2007, In : Pharmaceutical Research. 24, 2, p. 239-247 9 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Role of OATP transporters in the disposition of drugs

Niemi, M., 2007, In : Pharmacogenomics. 8, 7, p. 787-802 16 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Stereoselective interaction between the CYP2C8 inhibitor gemfibrozil and racemic ibuprofen

Tornio, A., Niemi, M., Neuvonen, P. J. & Backman, J. T., 2007, In : European Journal of Clinical Pharmacology. 63, 5, p. 463-469 7 p.

Research output: Contribution to journalArticleScientificpeer-review

2006

Association of genetic polymorphism in ABCC2 with hepatic multidrug resistance-associated protein 2 expression and pravastatin pharmacokinetics

Niemi, M., Arnold, K., Backman, J. T., Pasanen, M. K., Gödtel-Armbrust, U., Wojnowski, L., Zanger, U., Neuvonen, P. J., Eichelbaum, M., Kivistö, K. T. & Lang, T., 2006, In : Pharmacogenetics and Genomics. 16, 11, p. 801-808 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance

Neuvonen, P. J., Niemi, M. & Backman, J. T., 2006, In : Clinical Pharmacology and Therapeutics. 80, 6, p. 565-581 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect of SLCO1B1 polymorphism on induction of CYP3A4 by rifampicin

Kivistö, K. T., Diczfalusy, U., Bodin, K., Bertilsson, L., Fromm, M. F., Eichelbaum, M. & Niemi, M., 2006, In : Pharmacogenetics and Genomics. 16, 8, p. 565-568 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Farmakogenetiikka ja yksilöllinen lääkehoito [pääkirjoitus]

Translated title of the contribution: Pharmacogenetics and individualized drug therapy [Editorial]Niemi, M., 2006, In : Suomen lääkärilehti. 2006/61, p. 1079

Research output: Contribution to journalArticleScientific

Impact of the SLCO1B1 polymorphism on the pharmacokinetics and lipid-lowering efficacy of multiple-dose pravastatin

Igel, M., Arnold, K., Niemi, M., Hofmann, U., Schwab, M., Lutjohann, D., von Bergmann, K., Eichelbaum, M. & Kivistö, K. T., 2006, In : Clinical Pharmacology and Therapeutics. 79, 5, p. 419-426 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Itraconazole, gemfibrozil and their combination markedly raise the plasma concentrations of loperamide

Niemi, M., Tornio, A., Pasanen, M. K., Fredriksson, H., Neuvonen, P. J. & Backman, J. T., 2006, In : European Journal of Clinical Pharmacology. 62, 6, p. 463-472 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Montelukast and zafirlukast do not affect the pharmacokinetics of the CYP2C8 substrate pioglitazone

Jaakkola, T., Backman, J. T., Neuvonen, M., Niemi, M. & Neuvonen, P. J., 2006, In : European Journal of Clinical Pharmacology. 62, 7, p. 503-509 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Muscle symptoms associated with statins: a series of twenty patients

Soininen, K., Niemi, M., Kilkki, E., Strandberg, T. & Kivistö, K. T., 2006, In : Basic & Clinical Pharmacology & Toxicology. 98, 1, p. 51-54 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Pharmacokinetics and response to pravastatin in paediatric patients with familial hypercholesterolaemia and in paediatric cardiac transplant recipients in relation to polymorphisms of the SLCO1B1 and ABCB1 genes

Hedman, M., Antikainen, M., Holmberg, C., Neuvonen, M., Eichelbaum, M., Kivistö, K. T., Neuvonen, P. J. & Niemi, M., 2006, In : British Journal of Clinical Pharmacology. 61, 6, p. 706-715 10 p.

Research output: Contribution to journalArticleScientificpeer-review

SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin

Niemi, M., Pasanen, M. K. & Neuvonen, P. J., 2006, In : Clinical Pharmacology and Therapeutics. 80, 4, p. 356-366 11 p.

Research output: Contribution to journalArticleScientificpeer-review

SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid

Pasanen, M. K., Neuvonen, M., Neuvonen, P. J. & Niemi, M., 2006, In : Pharmacogenetics and Genomics. 16, 12, p. 873-879 7 p.

Research output: Contribution to journalArticleScientificpeer-review

2005

Acute effects of pravastatin on cholesterol synthesis are associated with SLCO1B1 (encoding OATP1B1) haplotype *17

Niemi, M., Neuvonen, P. J., Hofmann, U., Backman, J. T., Schwab, M., Lutjohann, D., von Bergmann, K., Eichelbaum, M. & Kivistö, K. T., 2005, In : Pharmacogenetics and Genomics. 15, 5, p. 303-309 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Coadministration of gemfibrozil and itraconazole has only a minor effect on the pharmacokinetics of the CYP2C9 and CYP3A4 substrate nateglinide

Niemi, M., Backman, J. T., Juntti-Patinen, L., Neuvonen, M. & Neuvonen, P. J., 2005, In : British Journal of Pharmacology. 60, 2, p. 208-217 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Cyclosporine markedly raises the plasma concentrations of repaglinide

Kajosaari, L., Niemi, M., Neuvonen, M., Laitila, J., Neuvonen, P. J. & Backman, J. T., 2005, In : Clinical Pharmacology and Therapeutics. 78, 4, p. 388-399 12 p.

Research output: Contribution to journalArticleScientificpeer-review

CYP3A5 genotype is associated with diagnosis of hypertension in elderly patients: data from the DEBATE Study

Kivistö, K. T., Niemi, M., Schaeffeler, E., Pitkälä, K., Tilvis, R., Fromm, M. F., Schwab, M., Lang, F., Eichelbaum, M., Strandberg, T. & Srandberg, T., 2005, In : American journal of Pharmacigenomics. 5, p. 191-195 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1)

Niemi, M., Kivistö, K. T., Hofmann, U., Schwab, M., Eichelbaum, M. & Fromm, M. F., 2005, In : British Journal of Clinical Pharmacology. 59, 5, p. 602-604 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics

Niemi, M., Backman, J. T., Kajosaari, L., Leathart, J. B., Neuvonen, M., Daly, A. K., Eichelbaum, M., Kivistö, K. T. & Neuvonen, P. J., 2005, In : Clinical Pharmacology and Therapeutics. 77, 6, p. 468-478 11 p.

Research output: Contribution to journalArticleScientificpeer-review

2004

Characterisation of cerivastatin as a P-glycoprotein substrate: studies in P-glycoprotein-expressing cell monolayers and mdr1a/b knock-out mice

Kivisto, K. T., Zukunft, J., Hofmann, U., Niemi, M., Rekersbrink, S., Schneider, S., Luippold, G., Schwab, M., Eichelbaum, M. & Fromm, M. F., 2004, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 370, p. 124-130 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Functional interaction of intestinal CYP3A4 and P-glycoprotein

Kivisto, K. T., Niemi, M. & Fromm, M. F., 2004, In : Fundamental & Clinical Pharmacology. 18, p. 621-626 6 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)

Niemi, M., Schaeffeler, E., Lang, T., Fromm, M. F., Neuvonen, M., Kyrklund, C., Backman, J. T., Kerb, R., Schwab, M., Neuvonen, P. J., Eichelbaum, M. & Kivisto, K. T., 2004, In : Pharmacogenetics and Genomics. 14, p. 429-440 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Lipid-lowering response to statins is affected by CYP3A5 polymorphism

Kivisto, K. T., Niemi, M., Schaeffeler, E., Pitkala, K., Tilvis, R. T., Fromm, M. F., Schwab, M., Eichelbaum, M. & Strandberg, T., 2004, In : Pharmacogenetics and Genomics. 14, p. 523-525 3 p.

Research output: Contribution to journalArticleScientificpeer-review