Mikko Niemi

Publications

Research Output per year

2000 2020

• 149 Article
• 15 Review Article
• 9 Chapter
• 1 Abstract
• 4 More
  • 1 Meeting Abstract
  • 1 Editorial
  • 1 Letter
  • 1 Patent

Research Output per year

Research Output per year

Search results

• 2005

  Acute effects of pravastatin on cholesterol synthesis are associated with SLCO1B1 (encoding OATP1B1) haplotype *17

  Niemi, M., Neuvonen, P. J., Hofmann, U., Backman, J. T., Schwab, M., Lutjohann, D., von Bergmann, K., Eichelbaum, M. & Kivistö, K. T., 2005, In : Pharmacogenetics and Genomics. 15, 5, p. 303-309 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Coadministration of gemfibrozil and itraconazole has only a minor effect on the pharmacokinetics of the CYP2C9 and CYP3A4 substrate nateglinide

  Niemi, M., Backman, J. T., Juntti-Patinen, L., Neuvonen, M. & Neuvonen, P. J., 2005, In : British Journal of Pharmacology. 60, 2, p. 208-217 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Cyclosporine markedly raises the plasma concentrations of repaglinide

  Kajosaari, L., Niemi, M., Neuvonen, M., Laitila, J., Neuvonen, P. J. & Backman, J. T., 2005, In : Clinical Pharmacology and Therapeutics. 78, 4, p. 388-399 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• CYP3A5 genotype is associated with diagnosis of hypertension in elderly patients: data from the DEBATE Study

  Kivistö, K. T., Niemi, M., Schaeffeler, E., Pitkälä, K., Tilvis, R., Fromm, M. F., Schwab, M., Lang, F., Eichelbaum, M., Strandberg, T. & Srandberg, T., 2005, In : American journal of Pharmacigenomics. 5, p. 191-195 5 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1)

  Niemi, M., Kivistö, K. T., Hofmann, U., Schwab, M., Eichelbaum, M. & Fromm, M. F., 2005, In : British Journal of Clinical Pharmacology. 59, 5, p. 602-604 3 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics

  Niemi, M., Backman, J. T., Kajosaari, L., Leathart, J. B., Neuvonen, M., Daly, A. K., Eichelbaum, M., Kivistö, K. T. & Neuvonen, P. J., 2005, In : Clinical Pharmacology and Therapeutics. 77, 6, p. 468-478 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2004

  Characterisation of cerivastatin as a P-glycoprotein substrate: studies in P-glycoprotein-expressing cell monolayers and mdr1a/b knock-out mice

  Kivisto, K. T., Zukunft, J., Hofmann, U., Niemi, M., Rekersbrink, S., Schneider, S., Luippold, G., Schwab, M., Eichelbaum, M. & Fromm, M. F., 2004, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 370, p. 124-130 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Effects of trimethoprim and rifampin on the pharmacokinetics of the cytochrome P4502C8 substrate rosiglitazone

  Niemi, M., Backman, J. T. & Neuvonen, P. J., 2004, In : Clinical Pharmacology and Therapeutics. 76, p. 239-249 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Functional interaction of intestinal CYP3A4 and P-glycoprotein

  Kivisto, K. T., Niemi, M. & Fromm, M. F., 2004, In : Fundamental & Clinical Pharmacology. 18, p. 621-626 6 p.

  Research output: Contribution to journal › Review Article › peer-review

• High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)

  Niemi, M., Schaeffeler, E., Lang, T., Fromm, M. F., Neuvonen, M., Kyrklund, C., Backman, J. T., Kerb, R., Schwab, M., Neuvonen, P. J., Eichelbaum, M. & Kivisto, K. T., 2004, In : Pharmacogenetics and Genomics. 14, p. 429-440 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Lipid-lowering response to statins is affected by CYP3A5 polymorphism

  Kivisto, K. T., Niemi, M., Schaeffeler, E., Pitkala, K., Tilvis, R. T., Fromm, M. F., Schwab, M., Eichelbaum, M. & Strandberg, T., 2004, In : Pharmacogenetics and Genomics. 14, p. 523-525 3 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Rifampicin reduces plasma concentrations of celiprolol

  Lilja, J. J., Niemi, M. & Neuvonen, P. J., 2004, In : European Journal of Clinical Pharmacology. 59, p. 819-824 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• The CYP2C8 inhibitor trimethoprim increases the plasma concentrations of repaglinide in healthy subjects

  Niemi, M., Kajosaari, L. I., Neuvonen, M., Backman, J. T. & Neuvonen, P. J., 2004, In : British Journal of Clinical Pharmacology. 57, 4, p. 441-447 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2003

  Effect of fluconazole on the pharmacokinetics and pharmacodynamics of nateglinide

  Niemi, M., Neuvonen, M., Juntti-Patinen, L., Backman, J. T. & Neuvonen, P. J., 2003, In : Clinical Pharmacology and Therapeutics. 74, p. 25-31 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Effect of rifampicin on the pharmacokinetics and pharmacodynamics of nateglinide in healthy subjects

  Niemi, M., Backman, J. T., Neuvonen, M. & Neuvonen, P. J., 2003, In : British Journal of Clinical Pharmacology. 56, p. 427-432 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: potentially hazardous interaction between gemfibrozil and repaglinide

  Niemi, M., Backman, J. T., Neuvonen, M. & Neuvonen, P. J., 2003, In : Diabetologia. 46, p. 347-351 5 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Gemfibrozil considerably increases the plasma concentrations of rosiglitazone

  Niemi, M., Backman, J. T., Schröder, M., Laitila, J., Neuvonen, M. & Neuvonen, P. J., 2003, In : Diabetologia. 46, 10, p. 1319-1323 5 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Pharmacokinetic interactions with rifampicin - Clinical relevance

  Niemi, M., Backman, J. T., Fromm, M. F., Neuvonen, P. J. & Kivisto, K. T., 2003, In : Clinical Pharmacokinetics. 42, p. 819-850 32 p.

  Research output: Contribution to journal › Review Article › peer-review

• Polymorphism in CYP2C8 is associated with reduced plasma concentrations of repaglinide

  Niemi, M., Leathart, J. B., Neuvonen, M. S., Backman, J. T., Daly, A. K. & Neuvonen, P. J., 2003, In : Clinical Pharmacology and Therapeutics. 74, p. 380-387 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2002

  Glyburide and glimepiride pharmacokinetics in subjects with different CYP2C9 genotypes

  Niemi, M., Cascorbi, I., Timm, R., Kroemer, H. K., Neuvonen, P. J. & Kivisto, K. T., 2002, In : Clinical Pharmacology and Therapeutics. 72, p. 326-332 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Plasma concentrations of inhaled budesonide and its effects on plasma cortisol are increased by the cytochrome P4503A4 inhibitor itraconazole

  Raaska, K., Niemi, M., Neuvonen, M., Neuvonen, P. J. & Kivisto, K. T., 2002, In : Clinical Pharmacology and Therapeutics. 72, p. 362-369 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2001

  Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of glimepiride

  Niemi, M., Neuvonen, P. J. & Kivisto, K. T., 2001, In : Clinical Pharmacology and Therapeutics. 70, p. 439-445 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Effects of fluconazole and fluvoxamine on the pharmacokinetics and pharmacodynamics of glimepiride

  Niemi, M., Backman, J. T., Neuvonen, M., Laitila, J., Neuvonen, P. J. & Kivisto, K. T., 2001, In : Clinical Pharmacology and Therapeutics. 69, p. 194-200 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Effects of rifampin on the pharmacokinetics and pharmacodynamics of glyburide and glipizide

  Niemi, M., Backman, J. T., Neuvonen, M., Neuvonen, P. J. & Kivisto, K. T., 2001, In : Clinical Pharmacology and Therapeutics. 69, p. 400-406 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• The cytochrome P4503A4 inhibitor clarithromycin increases the plasma concentrations and effects of repaglinide

  Niemi, M., Neuvonen, P. J. & Kivisto, K. T., 2001, In : Clinical Pharmacology and Therapeutics. 70, p. 58-65 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2000

  Effect of fluconazole on plasma fluvastatin and pravastatin concentrations

  Kantola, T., Backman, J. T., Niemi, M., Kivisto, K. T. & Neuvonen, P. J., 2000, In : European Journal of Clinical Pharmacology. 56, p. 225-229 5 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Effect of rifampicin on the pharmacokinetics and pharmacodynamics of glimepiride

  Niemi, M., Kivisto, K. T., Backman, J. T. & Neuvonen, P. J., 2000, In : British Journal of Clinical Pharmacology. 50, p. 591-595 5 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Rifampin decreases the plasma concentrations and effects of repaglinide

  Niemi, M., Backman, J. T., Neuvonen, M., Neuvonen, P. J. & Kivisto, K. T., 2000, In : Clinical Pharmacology and Therapeutics. 68, p. 495-500 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review