Research output per year
Research output per year
- 17 results
Search results
-
2025
ANO7 expression in the prostate modulates mitochondrial function and lipid metabolism
Löf, C., Sultana, N., Goel, N., Heron, S., Wahlström, G., House, A., Holopainen, M., Käkelä, R. & Schleutker, J., 8 Feb 2025, In: Cell Communication and Signaling. 23, 1, 19 p., 71.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Glucose-6-phosphate-dehydrogenase on old peroxisomes maintains self-renewal of epithelial stem cells after asymmetric cell division
Bui, H., Andersson, S., Sola-Carvajal, A., De Marchi, T., Vähäkangas, E., Holopainen, M., House, A. H., Rovenko, B. M., Englund, J. I., Kasper, M., Kuuluvainen, E., Käkelä, R., Hietakangas, V., Niméus, E. & Katajisto, P., 26 Apr 2025, In: Nature Communications. 16, 1, 14 p., 3932.Research output: Contribution to journal › Article › Scientific › peer-review
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Improvement of high-density lipoprotein atheroprotective properties in patients with systemic lupus erythematosus after belimumab treatment
Dedemadi, A., Gkolfinopoulou, C., Nikoleri , D., Nikoloudaki, M., Ruhanen, H., Holopainen, M., Käkelä, R., Christopoulou, G., Bournazos, S., Constantoulakis, P., Sidiropoulos, P., Bertsias, G. & Chroni , A., Feb 2025, In: Rheumatology. 64, 2, p. 648-657 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Seasonal and genetic effects on lipid profiles of juvenile Atlantic salmon
House, A. H., Debes, P. V., Holopainen, M., Käkelä, R., Donner, I., Frapin, M., Ahi, E. P., Kurko, J., Ruhanen, H. & Primmer, C. R., Jan 2025, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1870, 1, 10 p., 159565.Research output: Contribution to journal › Article › Scientific › peer-review
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2024
Fatty acid profiles reveal dietary variability of a large calanoid copepod Limnocalanus macrurus in the northern Baltic Sea
von Weissenberg, E., Ruhanen, H., Holopainen, M., Käkelä, R. & Engström-Öst, J., 7 Feb 2024, In: Frontiers in Marine Science. 11, 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Functional omics of ORP7 in primary endothelial cells
Taskinen, J. H., Holopainen, M., Ruhanen, H., van der Stoel, M., Käkelä, R., Ikonen, E., Keskitalo, S., Varjosalo, M. & Olkkonen, V. M., 18 Dec 2024, In: BMC Biology. 22, 1, 24 p., 292.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
2023
Fatty acid fingerprints in bronchoalveolar lavage fluid and its extracellular vesicles reflect equine asthma severity
Höglund, N., Nieminen, P., Mustonen, A.-M., Kakela, R., Tollis, S., Koho, N., Holopainen, M., Ruhanen, H. & Mykkanen, A., 17 Jun 2023, In: Scientific Reports. 13, 1, 14 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Lipid species profiling of bronchoalveolar lavage fluid cells of horses housed on two different bedding materials
Mönki, J., Holopainen, M., Ruhanen, H., Karikoski, N., Käkelä, R. & Mykkänen, A., 8 Dec 2023, In: Scientific Reports. 13, 21778 (2023).Research output: Contribution to journal › Article › Scientific › peer-review
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Small mitochondrial protein NERCLIN regulates cardiolipin homeostasis and mitochondrial ultrastructure
Konovalova, S., Torregrosa-Munumer, R., Manjunath, P., Liu, X., Baral, S., Fatima, K., Holopainen, M., Kvist, J., Rajendran, J., Yang, Y., Varjosalo, M., Käkelä, R., Somerharju, P. & Tyynismaa, H., 25 Jul 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 30, 9 p., e2210599120.Research output: Contribution to journal › Article › Scientific › peer-review
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2021
Lipidomic changes of LDL after consumption of Camelina sativa oil, fatty fish and lean fish in subjects with impaired glucose metabolism-A randomized controlled trial
Erkkilä, A. T., Manninen, S., Fredrikson, L., Bhalke, M., Holopainen, M., Ruuth, M., Lankinen, M., Käkelä, R., Öörni, K. & Schwab, U. S., 2021, In: Journal of Clinical Lipidology. 15, 5, p. 743-751 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Repetitive amiodarone administration causes liver damage via adipose tissue ER stress-dependent lipolysis, leading to hepatotoxic free fatty acid accumulation
Hubel, E., Fishman, S., Holopainen, M., Käkelä, R., Shaffer, O., Houri, I., Zvibel, I. & Shibolet, O., Sept 2021, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 321, p. G298-G307 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2020
Human Mesenchymal Stromal Cell Secretome Promotes the Immunoregulatory Phenotype and Phagocytosis Activity in Human Macrophages
Holopainen, M., Impola, U., Lehenkari, P., Laitinen, S. & Kerkela, E., Sept 2020, In: Cells. 9, 9, 18 p., 2142.Research output: Contribution to journal › Article › Scientific › peer-review
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2019
Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules
Valkonen, S., Holopainen, M., Colas, R. A., Impola, U., Dalli, J., Käkelä, R., Siljander, P.R.-M. & Laitinen, S., Aug 2019, In: Biochimica and Biophysica Acta. Molecular and Cell Biology of Lipids. 1864, 8, p. 1168-1182 15 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Polyunsaturated fatty acids modify the extracellular vesicle membranes and increase the production of proresolving lipid mediators of human mesenchymal stromal cells
Holopainen, M., Colas, R. A., Valkonen, S., Tigistu-Sahle, F., Hyvärinen, K., Mazzacuva, F., Lehenkari, P., Käkelä, R., Dalli, J., Kerkelä, E. & Laitinen, S., Oct 2019, In: Biochimica and Biophysica Acta. Molecular and Cell Biology of Lipids. 1864, 10, p. 1350-1362 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Vulnerability of invasive glioblastoma cells to lysosomal membrane destabilization
Le Joncour, V., Filppu, P., Hyvönen, M., Holopainen, M., Turunen, S. P., Sihto, H., Burghardt, I., Joensuu, H., Tynninen, O., Jääskeläinen, J., Weller, M., Lehti, K., Käkelä, R. & Laakkonen, P., Jun 2019, In: EMBO molecular medicine. 11, 6, 21 p., 9034.Research output: Contribution to journal › Article › Scientific › peer-review
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2018
Mesenchymal Stromal Cells and Their Extracellular Vesicles Enhance the Anti-Inflammatory Phenotype of Regulatory Macrophages by Downregulating the Production of Interleukin (IL)-23 and IL-22
Hyvärinen, K., Holopainen, M., Skirdenko, V., Ruhanen, H., Lehenkari, P., Korhonen, M., Käkelä, R., Laitinen, S. & Kerkelä, E., 12 Apr 2018, In: Frontiers in Immunology. 9, 13 p., 771.Research output: Contribution to journal › Article › Scientific › peer-review
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2017
Metabolism and phospholipid assembly of polyunsaturated fatty acids in human bone marrow mesenchymal stromal cells
Tigistu-Sahle, F., Lampinen, M., Kilpinen, L., Holopainen, M., Lehenkari, P., Laitinen, S. & Käkelä, R., Jan 2017, In: Journal of Lipid Research. 58, 1, p. 92-110 19 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile