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Publications 2008 2019

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2019

Acetalated Dextran Nanoparticles Loaded into an Injectable Alginate Cryogel for Combined Chemotherapy and Cancer Vaccination

Bauleth-Ramos, T., Shih, T-Y., Shahbazi, M-A., Najibi, A. J., Mao, A. S., Liu, D., Granja, P., Santos, H. A., Sarmento, B. & Mooney, D. J., Aug 2019, In : Advanced Functional Materials. 29, 35, 10 p., 1903686.

Research output: Contribution to journalArticleScientificpeer-review

Bacteria-assisted biogreen synthesis of radical scavenging exopolysaccharide-iron complexes: an oral nano-sized nutritional supplement with high in vivo compatibility

Niknezhad, S. V., Darzi, G. N., Kianpour, S., Jafarzadeh, S., Mohammadi, H., Ghasemi, Y., Heidari, R. & Shahbazi, M-A., 14 Sep 2019, In : Journal of Materials Chemistry. B. 7, 34, p. 5211-5221 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Targeted Reinforcement of Macrophage Reprogramming Toward M2 Polarization by IL-4-Loaded Hyaluronic Acid Particles (vol 1, pg 18444, 2018)

Shahbazi, M-A., Mahsa Sedighi, M. S., Bauleth-Ramos, T., Krishna Kant, K., Correia, A., Poursina, N., Sarmento, B., Hirvonen, J. T. & Almeida Santos, H., 28 Apr 2019, In : ACS Omega. 4, 3, p. 5931-5931 1 p.

Research output: Contribution to journalArticleScientificpeer-review

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2018

Conductive vancomycin-loaded mesoporous silica polypyrrole-based scaffolds for bone regeneration

Ezazi, N. Z., Shahbazi, M-A., Shatalin, Y. V., Nadal, E., Mäkilä, E., Salonen, J., Kemell, M., Correia, A., Hirvonen, J. & Santos, H. A., 30 Jan 2018, In : International Journal of Pharmaceutics. 536, 1, p. 241-250 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Targeted Reinforcement of Macrophage Reprogramming Towards M2 Polarization by IL-4 Loaded Hyaluronic Acid Particles

Shahbazi, M-A., Mahsa Sedighi, M. S., Bauleth-Ramos, T., Krishna Kant, K., Correia, A., Poursina, N., Sarmento, B., Hirvonen, J. T. & Almeida Santos, H., 18 Dec 2018, In : ACS Omega. 3, 12, p. 18444–18455 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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2017

A Multifunctional Nanocomplex for Enhanced Cell Uptake, Endosomal Escape and Improved Cancer Therapeutic Effect

Vingadas Almeida, P., Shahbazi, M-A., Correia, A., Mäkilä, E. M., Kemell, M. L., Salonen, J. & Almeida Santos, H., Jun 2017, In : Nanomedicine. 12, 12, p. 1401-1420 20 p.

Research output: Contribution to journalArticleScientificpeer-review

Coating Nanoparticles with Plant-Produced Transferrin-Hydrophobin Fusion Protein Enhances Their Uptake in Cancer Cells

Reuter, L. J., Shahbazi, M-A., Mäkilä, E. M., Salonen, J. J., Saberianfar, R., Menassa, R., Santos, H. A., Joensuu, J. J. & Ritala, A., Jun 2017, In : Bioconjugate Chemistry. 28, 6, p. 1639-1648 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Fabrication, characterization and evaluation of bacterial cellulose-based capsule shells for oral drug delivery

Ullah, H., Badshah, M., Mäkilä, E., Salonen, J., Shahbazi, M-A., Santos, H. A. & Khan, T., Mar 2017, In : Cellulose. 24, 3, p. 1445-1454 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Intracellular responsive dual delivery by endosomolytic polyplexes carrying DNA anchored porous silicon nanoparticles

Shahbazi, M-A., Almeida, P. V., Correia, A., Herranz-Blanco, B., Shrestha, N., Mäkilä, E., Salonen, J., Hirvonen, J. & Santos, H. A., 10 Mar 2017, In : Journal of Controlled Release. 249, p. 111-122 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Multistaged Nanovaccines based on Porous Silicon@Acetalated Dextran@Cancer Cell Membrane for Cancer Immunotherapy

Fontana, F., Shahbazi, M-A., Liu, D., Zhang, H., Mäkilä, E., Salonen, J., Hirvonen, J. T. & Almeida Santos, H., 13 Feb 2017, In : Advanced Materials. 29, 7, 9 p., 1603239.

Research output: Contribution to journalArticleScientificpeer-review

Nutlin-3a and Cytokine Co-loaded Spermine-Modified Acetalated Dextran Nanoparticles for Cancer Chemo-Immunotherapy

Bauleth-Ramos, T., Shahbazi, M-A., Liu, D., Fontana, F., Correia, A., Figueiredo, P., Zhang, H., Martins, J. P., Hirvonen, J. T., Granja, P., Sarmento, B. & Santos, H. A., 10 Nov 2017, In : Advanced Functional Materials. 27, 42, 14 p., 1703303.

Research output: Contribution to journalArticleScientificpeer-review

2016

Angiopep2-functionalized polymersomes for targeted doxorubicin delivery to glioblastoma cells

Figueiredo, P., Balasubramanian, V., Shahbazi, M-A., Correia, A., Wu, D., Palivan, C. G., Hirvonen, J. T. & Santos, H. A., 25 Sep 2016, In : International Journal of Pharmaceutics. 511, 2, p. 794-803 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Dual chitosan/albumin-coated alginate/dextran sulfate nanoparticles for enhanced oral delivery of insulin

Lopes, M., Shrestha, N., Correia, A., Shahbazi, M-A., Sarmento, B., Hirvonen, J., Veiga, F., Seica, R., Ribeiro, A. & Santos, H. A., 28 Jun 2016, In : Journal of Controlled Release. 232, p. 29-41 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Enhanced Photoluminescence in Acetylene-Treated ZnO Nanorods

Jäppinen, L., Jalkanen, T., Sieber, B., Addad, A., Heinonen, M., Kukk, E., Radevici, I., Paturi, P., Peurla, M., Shahbazi, M-A., Santos, H. A., Boukherroub, R., Santos, H., Lastusaari, M. & Salonen, J., 20 Sep 2016, In : Nanoscale Research Letters. 11, 11 p., 413.

Research output: Contribution to journalArticleScientificpeer-review

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In Vitro and In Vivo Assessment of Heart-Homing Porous Silicon Nanoparticles

Almeida Ferreira, M. P., Ranjan, S., Correia, A., Mäkilä, E., Kinnunen, S. M., Zhang, H., Shahbazi, M-A., Vingadas Almeida, P., Salonen, J., Ruskoaho, H. J., Airaksinen, A., Hirvonen, J. T. & Almeida Santos, H., Jul 2016, In : Biomaterials. 94, p. 93–104 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Oral hypoglycaemic effect of GLP-1 and DPP4 inhibitor based nanocomposites in a diabetic animal model

Shrestha, N., Araujo, F., Shahbazi, M-A., Mäkilä, E., Gomes, M. J., Airavaara, M., Kauppinen, E. I., Raula, J., Salonen, J., Hirvonen, J., Sarmento, B. & Santos, H. A., 28 Jun 2016, In : Journal of Controlled Release. 232, p. 113-119 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Thiolation and Cell-Penetrating Peptide Surface Functionalization of Porous Silicon Nanoparticles for Oral Delivery of Insulin

Shrestha, N., Araujo, F., Shahbazi, M-A., Makila, E., Gomes, M. J., Herranz-Blanco, B., Lindgren, R., Granroth, S., Kukk, E., Salonen, J., Hirvonen, J., Sarmento, B. & Santos, H. A., 24 May 2016, In : Advanced Functional Materials. 26, 20, p. 3405-3416 12 p.

Research output: Contribution to journalArticleScientificpeer-review

2015

A prospective cancer chemo-immunotherapy approach mediated by synergistic CD326 targeted porous silicon nanovectors

Shahbazi, M-A., Shrestha, N., Mäkilä, E., Araújo, F., Correia, A., Ramos, T., Sarmento, B., Salonen, J., Hirvonen, J. & Santos, H. A., May 2015, In : Nano Research . 8, 5, p. 1505-1521 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Controlled Shape and Nucleation Switching of Interfacially Polymerizable Nanoassemblies by Methyl Substitution

Shahbazi, M-A., Mäkilä, E., Shrestha, N., Salonen, J., Hirvonen, J. & Santos, H. A., 8 Dec 2015, In : Chemistry of Materials. 27, 23, p. 8170-8178 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Cyclodextrin-Modified Porous Silicon Nanoparticles for Efficient Sustained Drug Delivery and Proliferation Inhibition of Breast Cancer Cells

Correia, A., Shahbazi, M-A., Mäkilä, E., Almeida, S., Salonen, J., Hirvonen, J. & Santos, H. A., 21 Oct 2015, In : ACS Applied Materials & Interfaces. 7, 41, p. 23197-23204 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Microfluidic Assembly of a Multifunctional Tailorable Composite System Designed for Site Specific Combined Oral Delivery of Peptide Drugs

Araújo, F., Shrestha, N., Shahbazi, M-A., Liu, D., Herranz-Blanco, B., Mäkilä, E. M., Salonen, J. J., Hirvonen, J. T., Granja, P. L., Sarmento, B. & Santos, H. A., Aug 2015, In : ACS Nano. 9, 8, p. 8291-8302 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Multistage pH-responsive mucoadhesive nanocarriers prepared by aerosol flow reactor technology: A controlled dual protein-drug delivery system

Shrestha, N., Shahbazi, M-A., Araujo, F., Mäkilä, E., Raula, J., Kauppinen, E. I., Salonen, J., Sarmento, B., Hirvonen, J. & Santos, H. A., Nov 2015, In : Biomaterials. 68, p. 9-20 12 p.

Research output: Contribution to journalArticleScientificpeer-review

On-Chip Self-Assembly of a Smart Hybrid Nanocomposite for Antitumoral Applications

Herranz-Blanco, B., Liu, D., Mäkilä, E., Shahbazi, M-A., Ginestar, E., Zhang, H., Aseyev, V., Balasubramanian, V., Salonen, J., Hirvonen, J. & Santos, H. A., 11 Mar 2015, In : Advanced Functional Materials. 25, 10, p. 1488-1497 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Simple microfluidic approach to fabricate monodisperse hollow microparticles for multidrug delivery

Vasiliauskas, R., Liu, D., Cito, S., Zhang, H., Shahbazi, M-A., Sikanen, T., Mazutis, L. & Santos, H. A., 15 Jul 2015, In : ACS Applied Materials & Interfaces. 7, 27, p. 14822-14832 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Surface bioengineering of diatomite based nanovectors for efficient intracellular uptake and drug delivery

Terracciano, M., Shahbazi, M-A., Correia, A., Rea, I., Lamberti, A., De Stefano, L. & Santos, H. A., 2015, In : Nanoscale. 7, 47, p. 20063-20074 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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2014

Amine-modified hyaluronic acid-functionalized porous silicon nanoparticles for targeting breast cancer tumors

V. Almeida, P., Shahbazi, M-A., Mäkilä, E., Kaasalainen, M., Salonen, J., Hirvonen, J. & Santos, H. A., 2014, In : Nanoscale. 6, 17, p. 10377-10387 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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Augmented cellular trafficking and endosomal escape of porous silicon nanoparticles via zwitterionic bilayer polymer surface engineering

Shahbazi, M-A., V. Almeida, P., Mäkilä, E. M., Kaasalainen, M. H., Salonen, J. T., Hirvonen, J. T. & Santos, H. A., May 2014, In : Biomaterials. 35, 26, p. 7488–7500 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Chitosan-modified porous silicon microparticles for enhanced permeability of insulin across intestinal cell monolayers

Shrestha, N., Shahbazi, M-A., Araújo, F., Zhang, H., Mäkilä, E. M., Kauppila, J., Sarmento, B., Salonen, J. J., Hirvonen, J. T. & Santos, H. A., 17 May 2014, In : Biomaterials. 35, 25, p. 7172-7179 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Confinement Effects on Drugs in Thermally Hydrocarbonized Porous Silicon

Mäkilä, E., Ferreira, M. P. A., Kivelä, H., Niemi, S-M., Correia, A., Shahbazi, M-A., Kauppila, J., Hirvonen, J., Santos, H. A. & Salonen, J., 4 Mar 2014, In : Langmuir. 30, 8, p. 2196-2205 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Fabrication of a Multifunctional Nano-in-micro Drug Delivery Platform by Microfluidic Templated Encapsulation of Porous Silicon in Polymer Matrix

Zhang, H., Liu, D., Shahbazi, M-A., Mäkilä, E., Herranz Blanco, B., Salonen, J., Hirvonen, J. & Santos, H. A., 9 Jul 2014, In : Advanced Materials. 26, 26, p. 4497–4503 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Poly(methyl vinyl ether-alt-maleic acid)-Functionalized Porous Silicon Nanoparticles for Enhanced Stability and Cellular Internalization

Shahbazi, M-A., V. Almeida, P., Mäkilä, E., Correia, A., A. Ferreira, M. P., Kaasalainen, M., Salonen, J., Hirvonen, J. & Santos, H. A., Mar 2014, In : Macromolecular Rapid Communications. 35, 6, p. 624-629 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Surface Chemistry Dependent Immunostimulative Potential of Porous Silicon Nanoplatforms

Shahbazi, M-A., D. Fernández, T., Mäkilä, E. M., Le Guével, X., Mayorga, C., Kaasalainen, M. H., Salonen, J. J., Hirvonen, J. T. & Santos, H. A., Jul 2014, In : Biomaterials. 35, 33, p. 9224-9235 12 p.

Research output: Contribution to journalArticleScientificpeer-review

The impact of nanoparticles on the mucosal translocation and transport of GLP-1 across the intestinal epithelium

Araújo, F., Shrestha, N., Shahbazi, M-A., Fonte, P., Mäkilä, E. M., Salonen, J. J., Hirvonen, J. T., L Granja, P., Santos, H. A. & Sarmento, B., Jul 2014, In : Biomaterials. 35, 33, p. 9199-9207 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2013

Benzathine penicillin G: a model for long-term pharmacokinetic comparison of parenteral long-acting formulations

Shahbazi, M. A., Azimi, K. & Hamidi, M., 2013, In : Journal of Clinical Pharmacy and Therapeutics. 38, 2, p. 131-135

Research output: Contribution to journalArticleScientificpeer-review

Diatom silica microparticles for sustained release and permeation enhancement following oral delivery of prednisone and mesalamine

Zhang, H., Shahbazi, M-A., Mäkilä, E. M., da Silva, T. H., Reis, R. L., Salonen, J., Hirvonen, J. T. & Santos, H. A., Dec 2013, In : Biomaterials. 34, 36, p. 9210–9219 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Improving Oral Absorption via Drug-Loaded Nanocarriers: Absorption Mechanisms, Intestinal Models and Rational Fabrication

Shahbazi, M-A. & A. Santos, H., 2013, In : Current Drug Metabolism. 14, 1, p. 28-56 29 p.

Research output: Contribution to journalArticleScientificpeer-review

Preparation, optimization, and in-vitro/in-vivo/ex-vivo characterization of chitosan-heparin nanoparticles: drug-induced gelation

Shahbazi, M-A., Hamidi, M. & Mohammadi-Samani, S., 2013, In : Journal of Pharmacy and Pharmacology. 65, 8, p. 1118-1133

Research output: Contribution to journalArticleScientificpeer-review

The impact of preparation parameters on typical attributes of chitosan-heparin nanohydrogels: particle size, loading efficiency, and drug release

Shahbazi, M-A. & Hamidi, M., 2013, In : Drug Development and Industrial Pharmacy. 39, 11, p. 1774-1782 9 p.

Research output: Contribution to journalArticleScientificpeer-review

The mechanisms of surface chemistry effects of mesoporous silicon nanoparticles on immunotoxicity and biocompatibility

Shahbazi, M-A., Hamidi, M., Mäkilä, E. M., Zhang, H., Almeida, P. V., Kaasalainen, M., Salonen, J. J., Hirvonen, J. T. & Santos, H. A., Oct 2013, In : Biomaterials. 34, 31, p. 7776–7789 14 p.

Research output: Contribution to journalArticleScientificpeer-review

2012

A New Facilitated Solid Phase Extraction Method for Bioavailability Evaluation of Lisinopril in Fasting Healthy Male Volunteers

Foroozesh, M., Hamidi, M., Shahbazi, M-A. & Sahraei, M-A., 2012, In : Current Pharmaceutical Analysis. 8, 4, p. 431-439 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Copolymers: efficient carriers for intelligent nanoparticulate drug targeting and gene therapy

Hamidi, M., Shahbazi, M-A. & Rostamizadeh, K., 2012, In : Macromolecular Bioscience. 12, 2, p. 144-164 21 p.

Research output: Contribution to journalArticleScientificpeer-review

2011

Bioequivalence evaluation of a triamterene-hydrochlorothiazide generic product: a new bioequivalence index for fixed-dose combinations.

Hamidi, M., Shahbazi, M-A. & Azimi, K., 2011, In : Regulatory Toxicology and Pharmacology. 59, 1, p. 149-156 8 p.

Research output: Contribution to journalArticleScientificpeer-review

2009

A simple and sensitive HPLC-UV method for quantitation of lovastatin in human plasma: application to a bioequivalence study.

Hamidi, M., Zarei, N. & Shahbazi, M-A., 2009, In : Biological & Pharmaceutical Bulletin. 32, 9, p. 1600-1603

Research output: Contribution to journalArticleScientificpeer-review