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Publications 2008 2019

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2019

Dasatinib and navitoclax act synergistically to target NUP98-NSD1(+)/FLT3-ITD+ acute myeloid leukemia

Kivioja, J. L., Thanasopoulou, A., Kumar, A., Kontro, M., Yadav, B., Majumder, M. M., Javarappa, K. K., Eldfors, S., Schwaller, J., Porkka, K. & Heckman, C. A., Jun 2019, In : Leukemia. 33, 6, p. 1360-1372 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer

Malyutina, A., Majumder, M. M., Wang, W., Pessia, A., Heckman, C. A. & Tang, J., 20 May 2019, In : PLoS Computational Biology. 15, 5, p. e1006752 19 p., 1006752.

Research output: Contribution to journalArticleScientificpeer-review

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2018

Improving genomics-based predictions for precision medicine through active elicitation of expert knowledge

Sundin, I., Peltola, T., Micallef, L., Afrabandpey, H., Soare, M., Majumder, M. M., Daee, P., He, C., Serim, B., Havulinna, A., Heckman, C., Jacucci, G., Marttinen, P. & Kaski, S., 1 Jul 2018, In : Bioinformatics. 34, 13, p. 395-403 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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2017

Drug sensitivity profiling identifies potential therapies for lymphoproliferative disorders with overactive JAK/STAT3 signaling

Kuusanmäki, H., Dufva, O., Parri, E., van Adrichem, A. J., Rajala, H., Majumder, M. M., Yadav, B., Parsons, A., Chan, W. C., Wennerberg, K., Mustjoki, S. & Heckman, C. A., 14 Nov 2017, In : Oncotarget. 8, 57, p. 97516-97527 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML

Malani, D., Murumagi, A., Yadav, B., Kontro, M., Eldfors, S., Kumar, A., Karjalainen, R., Majumder, M. M., Ojamies, P., Pemovska, T., Wennerberg, K., Heckman, C., Porkka, K., Wolf, M., Aittokallio, T. & Kallioniemi, O., May 2017, In : Leukemia. 31, 5, p. 1187-1195 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia

Kontro, M., Kumar, A., Majumder, M. M., Eldfors, S., Parsons, A., Pemovska, T., Saarela, J. S., Yadav, B., Malani, D. R., Fløisand, Y., Höglund, M., Remes, K., Gjertsen, B-T., Kallioniemi, O-P., Wennerberg, J. K., Heckman, C. A. & Porkka, K. V. K., 2017, In : Leukemia. 31, 2, p. 301-309 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Idelalisib sensitivity and mechanisms of disease progression in relapsed TCF3-PBX1 acute lymphoblastic leukemia

Eldfors, S., Kuusanmäki, H., Kontro, M., Majumder, M. M., Parsons, A., Edgren, H., Pemovska, T., Kallioniemi, O., Wennerberg, K., Gökbuget, N., Burmeister, T., Porkka, K. & Heckman, C. A., 2017, In : Leukemia. 31, 1, p. 51-57 7 p.

Research output: Contribution to journalArticleScientificpeer-review

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Identification of precision treatment strategies for relapsed/refractory multiple myeloma by functional drug sensitivity testing

Majumder, M. M., Silvennoinen, R., Anttila, P., Tamborero, D., Eldfors, S., Yadav, B., Karjalainen, R., Kuusanmaki, H., Lievonen, J., Parsons, A., Suvela, M., Jantunen, E., Porkka, K. & Heckman, C. A., 22 Aug 2017, In : Oncotarget. 8, 34, p. 56338-56350 13 p.

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JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell-induced protection of AML

Karjalainen, R., Pemovska, T., Popa, M., Liu, M., Javarappa, K. K., Majumder, M. M., Yadav, B., Tamborero, D., Tang, J., Bychkov, D., Kontro, M., Parsons, A., Suvela, M., Safont, M. M., Porkka, K., Aittokallio, T., Kallioniemi, O., McCormack, E., Gjertsen, B. T., Wennerberg, K. & 2 othersKnowles, J. & Heckman, C. A., 10 Aug 2017, In : Blood. 130, 6, p. 789-802 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

The polycomb group protein BMI-1 inhibitor PTC-209 is a potent anti-myeloma agent alone or in combination with epigenetic inhibitors targeting EZH2 and the BET bromodomains

Alzrigat, M., Párraga, A. A., Majumder, M. M., Ma, A., Jin, J., Österborg, A., Nahi, H., Nilsson, K., Heckman, C. A., Öberg, F., Kalushkova, A. & Jernberg-Wiklund, H., 2017, In : Oncotarget. 8, 61, p. 103731-103743 13 p.

Research output: Contribution to journalArticleScientificpeer-review

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2015

Novel drug candidates for blast phase chronic myeloid leukemia from high-throughput drug sensitivity and resistance testing

Pietarinen, P. O., Pemovska, T., Kontro, M., Yadav, B., Mpindi, J. P., Andersson, E. I., Majumder, M. M., Kuusanmaki, H., Koskenvesa, P., Kallioniemi, O., Wennerberg, K., Heckman, C. A., Mustjoki, S. & Porkka, K., May 2015, In : Blood cancer journal. 5, 6 p., 309.

Research output: Contribution to journalArticleScientificpeer-review

2014

Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia

Kontro, M., Kuusanmaki, H., Eldfors, S., Burmeister, T., Andersson, E. I., Bruserud, O., Bruemmendorf, T. H., Edgren, H., Gjertsen, B. T., Itala-Remes, M., Lagström, S., Lohi, O., Lundan, T., Marti, J. M. L., Majumder, M. M., Parsons, A., Pemovska, T., Rajala, H., Vettenranta, K., Kallioniemi, O. & 3 othersMustjoki, S., Porkka, K. & Heckman, C. A., Aug 2014, In : Leukemia. 28, 8, p. 1738-1742 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies

Yadav, B., Pemovska, T., Szwajda, A., Kulesskiy, E., Kontro, M., Karjalainen, R., Majumder, M. M., Malani, D., Murumagi, A., Knowles, J., Porkka, K., Heckman, C., Kallioniemi, O., Wennerberg, K. & Aittokallio, T., 5 Jun 2014, In : Scientific Reports. 4, 10 p., 5193.

Research output: Contribution to journalArticleScientificpeer-review

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2013

Individualized Systems Medicine Strategy to Tailor Treatments for Patients with Chemorefractory Acute Myeloid Leukemia

Pemovska, T., Kontro, M., Yadav, B., Edgren, H., Eldfors, S., Szwajda, A., Almusa, H., Bespalov, M. M., Ellonen, P., Elonen, E., Gjertsen, B. T., Karjalainen, R., Kulesskiy, E., Lagström, S., Lehto, A., Lepistö, M., Lundan, T., Majumder, M. M., Marti, J. M. L., Mattila, P. & 16 othersMurumagi, A., Mustjoki, S., Palva, A., Parsons, A., Pirttinen, T., Ramet, M. E., Suvela, M., Turunen, L., Vastrik, I., Wolf, M., Knowles, J., Aittokallio, T., Heckman, C. A., Porkka, K., Kallioniemi, O. & Wennerberg, K., Dec 2013, In : Cancer Discovery. 3, 12, p. 1416-1429 14 p.

Research output: Contribution to journalArticleScientificpeer-review

2012

Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation

Groth, P., Luis Orta, M., Elvers, I., Majumder, M. M., Lagerqvist, A. & Helleday, T., 2012, In : Nucleic Acids Research. 40, 14, p. 6585-94 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia

Koskela, H. L. M., Eldfors, S., Ellonen, P., van Adrichem, A. J., Kuusanmäki, H., Andersson, E. I., Lagström, S., Clemente, M. J., Olson, T., Jalkanen, S. E., Majumder, M. M., Almusa, H., Edgren, H., Lepistö, M., Mattila, P., Guinta, K., Koistinen, P., Kuittinen, T., Penttinen, K., Parsons, A. & 9 othersKnowles, J., Saarela, J., Wennerberg, K., Kallioniemi, O., Porkka, K., Loughran, T. P., Heckman, C. A., Maciejewski, J. P. & Mustjoki, S., 2012, In : New England Journal of Medicine. 366, 20, p. 1905-1913 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2010

Methylated DNA Causes a Physical Block to Replication Forks Independently of Damage Signalling, O6-Methylguanine or DNA Single-Strand Breaks and Results in DNA Damage

01. Petra Groth, Simon Ausländer, Muntasir Mamun Majumder, Niklas Schultz, Fredrik Johansson, Eva Petermann, Thomas Helleday., 2010, In : Journal of Molecular Biology. 402, p. 70-82

Research output: Contribution to journalArticleScientificpeer-review

2009

Analgesic and Antioxidant Potential of the Leaves of Mikania scandens (L.) Willd.

S. M. Raquibul Hasan, Mariam Jamila, Muntasir Mamun Majumder, Raushanara Akter, Md. Mokarram Hossain, Md. Ehsanul Hoque Mazumder, Md. Ashraful Alam, Rumana Jahangir, Md. Sohel Rana , and Shafiqur Rahman. , 2009, In : American Journal of Pharmacology and Toxicology. 4, 1, p. 1-7

Research output: Contribution to journalArticleScientificpeer-review

Antinociceptive and gastro-protective effect of the ethanolic extract of the flowering top of Anthocephalus Cadamba Roxb

Md Ashraful Alam, Nusrat Subhan, Md Mostafizur Rahman, Kamaluddin Ahmed, Abdul Ghani, SM Raquibul Hasan, Md Mokarram Hossain, Raushanara Akter, Muntasir Mamun Majumder, 2009, In : Oriental Pharmacy And Experimental Medicine. 9, 12, p. 326-334

Research output: Contribution to journalArticleScientificpeer-review

2008

Antidiarrhoeal property of the hydroethanolic extract of the flowering tops of Anthocephalus cadamba.

M. Ashraful Alam, Raushanara Akter, Nusrat Subhan, M. Mostafizur Rahman, Muntasir M. Majumder, Lutfun Nahar, Satyajit D. Sarker, 2008, In : Revista Brasileira de Farmacognosia. 18, 2, p. 155-159

Research output: Contribution to journalArticleScientificpeer-review

Antioxidant and membrane stabilizing properties of Ichnocarpus frutescens.

Muntasir M. Majumder, Ehsanul H. Mazumder, M. Ashraful Alam, Raushanara Akter, Mustafizur Rahman, Satyajit D. Sarker. , 2008, In : Journal of Natural Remedies. 8, 1

Research output: Contribution to journalArticleScientificpeer-review

Antioxidant and membrane stabilizing properties of the flowering tops of Anthocephalus cadamba

Alam MA, Ghani A, Subhan N, Rahman MM, Haque MS, Majumder MM, Mazumder MEH, Akter RA, Nahar L and Sarker S D, 2008, In : Natural Product Communications. 3, 1, p. 65-70

Research output: Contribution to journalArticleScientificpeer-review

Dissolution study of some commercially available sustained release Diclofenac sodium tablet dosage forms.

Raushanara Akter, SM Raquibul Hasan, Abdullah Faruque, Ehsanul Hoque Mazumder, Moni Rahi Saha, Muntasir Mamun Majumder, Md. Ashraful Alam, Md. Mokarram Hossain , 2008, In : Bangladesh journal of life sciences. 21, 1, p. 143-146

Research output: Contribution to journalArticleScientificpeer-review

Evaluation of analgesic and antioxidant potential of the leaves of Curcuma alismatifolia Gagnep

Raushanara Akter, S.M. Raquibul Hasan, Samira Ayesha Siddiqua, Muntasir Mamun Majumder, Md. Mokarram Hossain, Md. Ashraful Alam, Shamsul Haque and Abdul Ghani. , 2008, In : Stamford journal of Pharmaceutical Sciences. 1, p. 3-9

Research output: Contribution to journalArticleScientificpeer-review

In-vitro evaluation of Antioxidant potential of the Leaves of Opuntia dillenii

Raushanara Akter, S.M. Raquibul Hasan, Muntasir M. Majumder, Md. Makarram Hussain, Masuda Akter., 2008, In : Stamford journal of Pharmaceutical Sciences. 2, 1, p. 22-26

Research output: Contribution to journalArticleScientificpeer-review