20142020

Research output per year

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Personal profile

Fields of Science

  • 3121 Internal medicine

International and National Collaboration Publications and projects within past five years.

Publications

Immune profiles in acute myeloid leukemia bone marrow associate with patient age, T-cell receptor clonality, and survival

Brück, O., Dufva, O., Hohtari, H., Blom, S., Turkki, R., Ilander, M., Kovanen, P., Pallaud, C., Ramos, P. M., Lähteenmäki, H., Välimäki, K., El Missiry, M., Ribeiro, A., Kallioniemi, O., Porkka, K., Pellinen, T. & Mustjoki, S., 28 Jan 2020, In : Blood advances. 4, 2, p. 274-286 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Integrated drug profiling and CRISPR screening identify essential pathways for CAR T-cell cytotoxicity

Dufva, O., Koski, J., Maliniemi, P., Ianevski, A., Klievink, J., Leitner, J., Pölönen, P., Hohtari, H., Saeed, K., Hannunen, T., Ellonen, P., Steinberger, P., Kankainen, M., Aittokallio, T., Keränen, M. A. I., Korhonen, M. & Mustjoki, S., 27 Feb 2020, In : Blood. 135, 9, p. 597-609 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia

Kuusanmäki, H., Leppä, A-M., Pölönen, P., Kontro, M., Dufva, O., Deb, D., Yadav, B., Bruck, O., Kumar, A., Everaus, H., Gjertsen, B. T., Heinäniemi, M., Porkka, K., Mustjoki, S. & Heckman, C. A., 1 Mar 2020, In : Haematologica. 105, 3, p. 708-720 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Data-driven characterization of molecular phenotypes across heterogeneous sample collections

Mehtonen, J., Polonen, P., Häyrynen, S., Dufva, O., Lin, J., Liuksiala, T., Granberg, K., Lohi, O., Hautamäki, V., Nykter, M. & Heinäniemi, M., 26 Jul 2019, In : Nucleic Acids Research. 47, 13, 12 p., 76.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target

Dufva, O., Kankainen, M., Kelkka, T., Sekiguchi, N., Awad, S. A., Eldfors, S., Yadav, B., Kuusanmäki, H., Malani, D., Andersson, E. I., Pietarinen, P., Saikko, L., Kovanen, P. E., Ojala, T., Lee, D. A., Loughran, T. P., Nakazawa, H., Suzumiya, J., Suzuki, R., Ko, Y. H. & 7 others, Kim, W. S., Chuang, S-S., Aittokallio, T., Chan, W. C., Ohshima, K., Ishida, F. & Mustjoki, S., 19 Apr 2018, In : Nature Communications. 9, 12 p., 1567.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Prizes

Helsinki Challenge

Jing Tang (Recipient), Samu Kurki (Recipient), Tero Antero Aittokallio (Recipient), Emma I. Andersson (Recipient), Evgeny Kulesskiy (Recipient), Ashwini Kumar (Recipient), Dimitrios Tsallos (Recipient), MM Majumder (Recipient), Olli Markus Juhani Dufva (Recipient) & Mikko Keränen (Recipient), 22 Nov 2017

Prize: Prizes and awards