Research output per year
Research output per year
Personal profile
Fields of Science
- 1182 Biochemistry, cell and molecular biology
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Clonal hematopoiesis is associated with distinct rheumatoid arthritis phenotypes
FinnGen, Hiitola, E., Korhonen, J., Kokkonen, H., Koskela, J., Kankainen, M., Alakuijala, M., Liu, A., Lundgren, S., Häppölä, P., Almusa, H., Ellonen, P., Savola, P., Kelkka, T., Leirisalo-Repo, M., Koivuniemi, R., Peltomaa, R., Pirilä, L., Isomäki, P. & Kauppi, M. & 10 others, , 30 Apr 2025, In: Science Advances. 11, 18, 14 p., eadt9846.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
JAK2/JAK2V617F heterodimers activate STAT1 and AhR to promote thrombocytosis
Skoda, R. C. & Silvennoinen, O., 11 Nov 2025, In: Journal of Experimental Medicine. 222, 12, 3 p., e20251880.Research output: Contribution to journal › Editorial › Scientific
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Molecular basis of JAK kinase regulation guiding therapeutic approaches: Evaluating the JAK3 pseudokinase domain as a drug target
Virtanen, A., Kettunen, V., Musta, K., Räkköläinen, V., Knapp, S., Haikarainen, T. & Silvennoinen, O., Jan 2025, In: Advances in Biological Regulation. 95, 11 p., 101072.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Verisolujen geneettiset muutokset yleisiä nivelreumassa = Clonal hematopoiesis is associated with distinct rheumatoid arthritis phenotypes
Hiitola, E., Korhonen, J., Kokkonen, H., Koskela, J., Kankainen, M., Alakuijala, M., Liu, A., Lundgren, S., Häppölä, P., Almusa, H., Ellonen, P., Savola, P., Kelkka, T., Leirisalo-Repo, M., Koivuniemi, R., Peltomaa, R., Pirilä, L., Isomäki, P., Kauppi, M. & Kaipiainen-Seppänen, O. & 10 others, , 2025, In: Duodecim. 141, 12, p. 115-116 2 p.Research output: Contribution to journal › Comment/debate › Professional
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Functional and Structural Characterization of Clinical-Stage Janus Kinase 2 Inhibitors Identifies Determinants for Drug Selectivity
Miao, Y., Virtanen, A., Zmajkovic, J., Hilpert, M., Skoda, R. C., Silvennoinen, O. & Haikarainen, T., 6 Jun 2024, In: Journal of Medicinal Chemistry. 67, 12, p. 10012–10024 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
Projects
- 2 Active
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Molecular basis of JAK kinase regulation in cytokine siganaling - Towards selective therapies in hematological and inflammatory diseases
Silvennoinen, O. J. (Project manager), Obaji, E. O. (Participant) & Virtanen, A. T. (Participant)
Suomen Akatemia Projektilaskutus
01/09/2024 → 31/08/2028
Project: Research Council of Finland: Academy Project
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Biocenter: FIRI2023: Biocenter Finland
Alitalo, K. (Project manager), Donner, K. M. (Project manager), Kuure, S. (Project manager), Nieminen, A. I. (Project manager), Silvennoinen, O. J. (Project manager) & Varjosalo, M. (Project manager)
Academy of Finland, Suomen Akatemia Projektilaskutus
01/01/2024 → 31/12/2025
Project: Research Council of Finland: Research infrastructure