Photo of Osamu Shimmi

Osamu Shimmi

  • PL 65 (Viikinkaari 1)

    00014

    Finland

20052019

Research activity per year

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Personal profile

Description of research and teaching

Research summary: A key issue in biology is to uncover the mechanisms employed by conserved signaling pathways to generate morphological diversity. The Bone Morphogenetic Proteins (BMPs), members of the TGF-beta superfamily, are a family of highly conserved secreted growth factors involved in metazoan developmental processes as diverse as cell proliferation, apoptosis, differentiation and cell-fate determination. Our studies intend to unveil the mechanisms of how spatial distribution of BMP ligands is regulated for pattern formation and how its modifications contribute to morphological variations in Drosophila and other species.

Teaching: Advanced developmental biology, Stem cells and organogenesis, Developmental biology practical course

Fields of Science

  • 1184 Genetics, developmental biology, physiology
  • developmental biology
  • Drosophila development
  • TGF-beta/BMP family signaling
  • morphogen diffusion
  • 1182 Biochemistry, cell and molecular biology
  • epithelial cells
  • Signal transduction
  • morphogenesis

International and National Collaboration

Publications and projects within past five years.
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