Personal profile
Fields of Science
- 3111 Biomedicine
Collaborations and top research areas from the last five years
Research output
- 5 Article
-
Diverse oncogenes use common mechanisms to drive growth of major forms of human cancer
Kauko, O., Turunen, M., Pihlajamaa, P., Häkkinen, A., Queiroz, R. M. L., Pääkkönen, M., Ventelä, S., Gaetani, M., Lundström, S. L., Murgia, A., Sahu, B., Routila, J., Wei, G. H., Irjala, H., Griffin, J. L., Lilley, K. S., Kivioja, T., Hautaniemi, S. & Taipale, J., 20 Aug 2025, In: Science Advances. 11, 34, 20 p., eadt1798.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Drug target proteome profiling identifies HES1-driven mitotic catastrophe in ovarian serous carcinoma
Bao, J., Pikkusaari, S., Dai, J., Leppiniemi, S., Huang, W., Yang, W., Anil, A., Pääkkönen, M., Lei, C., Mendoza-Ortiz, E. D., Karagöz, E., Eriksson, J., Li, M., Hynninen, J., Kauko, O., Färkkilä, A., Vähärautio, A., Hautaniemi, S., Kauppi, L. & Tang, J., Dec 2025, In: Biomedicine & Pharmacotherapy. 193, 13 p., 118716.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
PP2A-based triple-strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells
Denisova, O. V., Merisaari, J., Huhtaniemi, R., Qiao, X., Yetukuri, L., Jumppanen, M., Kaur, A., Paakkonen, M., von Schantz-Fant, C., Ohlmeyer, M., Wennerberg, K., Kauko, O., Koch, R., Aittokallio, T., Taipale, M. & Westermarck, J., Sept 2023, In: Molecular oncology. 17, 9, p. 1803-1820 18 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
PP2A methylesterase PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers
Aakula, A., Isomursu, A., Rupp, C., Erickson, A., Gupta, N., Kauko, O., Shah, P., Padzik, A., Pokharel, Y. R., Kaur, A., Li, S.-P., Trotman, L., Taimen, P., Rannikko, A., Lammerding, J., Paatero, I., Mirtti, T., Ivaska, J. & Westermarck, J., Jun 2023, In: Molecular oncology. 17, 6, p. 1007-1023 17 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
A competitive precision CRISPR method to identify the fitness effects of transcription factor binding sites
Pihlajamaa, P., Kauko, O., Sahu, B., Kivioja, T. & Taipale, J., 26 Sept 2022, In: Nature Biotechnology. 41, p. 197–203 26 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
Projects
- 1 Finished
-
COETG: Centre of Excellence in Tumor Genetics Research
Papadopoulos, P. (Project manager), Du, Y. (Participant), Dönges, S. I. (Participant), Kaasinen, E. (Participant), Kauko, O. J. (Participant), Kujanpää, J. P. (Participant), Norri, T. (Participant), Osmala, M. A. (Participant), Palin, K. (Participant), Pihlajamaa, P. (Participant), Prajapati, R. K. (Participant), Raitila, A. (Participant), Rantanen, F. M. (Participant), Wang, Z. (Participant) & Zou, S. (Participant)
Suomen Akatemia Projektilaskutus
01/01/2023 → 31/12/2025
Project: Research Council of Finland: Centre of Exellence