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Publications 1996 2018

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2018

Drug-Sensitivity Screening and Genomic Characterization of 45 HPV-Negative Head and Neck Carcinoma Cell Lines for Novel Biomarkers of Drug Efficacy

Lepikhova, T., Karhemo, P-R., Louhimo, R., Yadav, B., Murumägi, A., Kulesskiy, E., Kivento, M., Sihto, H., Grenman, R., Syrjänen, S. M., Kallioniemi, O., Aittokallio, T., Wennerberg, K., Joensuu, H. & Monni, O., Sep 2018, In : Molecular Cancer Therapeutics. 17, 9, p. 2060-2071 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Liprin-alpha 1 modulates cancer cell signaling by transmembrane protein CD82 in adhesive membrane domains linked to cytoskeleton

Pehkonen, H., Lento, M., von Nandelstadh, P., Filippou, A., Grenman, R., Lehti, K. & Monni, O., 13 Jul 2018, In : Cell Communication and Signaling. 16, 1, 14 p., 41.

Research output: Contribution to journalArticleScientificpeer-review

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2016

Liprin-alpha 1 is a regulator of vimentin intermediate filament network in the cancer cell adhesion machinery

Pehkonen, H., von Nandelstadh, P., Karhemo, P-R., Lepikhova, T., Grenman, R., Lehti, K. & Monni, O., 14 Apr 2016, In : Scientific Reports. 6, 15 p., 24486.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Par6G suppresses cell proliferation and is targeted by loss-of-function mutations in multiple cancers

Marques, E., Englund, J. I., Tervonen, T. A., Virkunen, E., Laakso, M., Myllynen, M., Mäkelä, A., Ahvenainen, M., Lepikhova, T., Monni, O., Hautaniemi, S. & Klefstrom, J., 17 Mar 2016, In : Oncogene. 35, 11, p. 1386-1398 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
2015

Identification of several potential chromatin binding sites of HOXB7 and its downstream target genes in breast cancer

Heinonen, H., Lepikhova, T., Sahu, B., Pehkonen, H. M., Pihlajamaa, P., Louhimo, R., Gao, P., Wei, G-H., Hautaniemi, S., Jänne, O. A. & Monni, O. M., 2015, In : International Journal of Cancer. 137, 10, p. 2374-2383 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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2012

Comparative analysis of algorithms for integration of copy number and expression data

Louhimo, R., Lepikhova, T., Monni, O. & Hautaniemi, S., 2012, In : Nature methods. 9, 4, p. 351-U50 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Systems-Level Analysis of Clinically Different Phenotypes of Juvenile Nasopharyngeal Angiofibromas

Renkonen, S., Kankainen, M., Hagström, J., Haglund, C., Monni, O. & Mäkitie, A. A., 2012, In : Laryngoscope. 122, 12, p. 2728–2735 8 p.

Research output: Contribution to journalArticleScientificpeer-review

2011

Comprehensive exon array data processing method for quantitative analysis of alternative spliced variants

Chen, P., Lepikhova, T., Hu, Y., Monni, O. & Hautaniemi, S., 2011, In : Nucleic Acids Research. 39, 18, p. e123 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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2010

Gene Expression of Analysis Identifies Over-expression of CXCL1, SPARC, SPP1, and SULF1 in Gastric Cancer

Junnila, S., Kokkola, A., Mizuguchi, T., Hirata, K., Karjalainen-Lindsberg, M., Puolakkainen, P. & Monni, O., 2010, In : Genes, Chromosomes & Cancer. 49, 1, p. 28-39 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Genome-wide gene copy number and expression analysis of primary gastric tumors and gastric cancer cell lines

Junnila, S., Kokkola, A., Karjalainen-Lindsberg, M., Puolakkainen, P. & Monni, O., 2010, In : BMC Cancer. 10, p. 73 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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PPFIA1 and CCND1 are frequently coamplified in breast cancer

Dancau, A-M., Wuth, L., Waschow, M., Holst, F., Krohn, A., Choschzick, M., Terracciano, L., Politis, S., Kurtz, S., Lebeau, A., Friedrichs, K., Wencke, K., Monni, O. & Simon, R., 2010, In : Genes, Chromosomes & Cancer. 49, 1, p. 1-8 8 p.

Research output: Contribution to journalArticleScientificpeer-review

2009

15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer

Thiel, A., Ganesan, A., Mrena, J., Junnila, S., Nykänen, A., Hemmes, A., Tai, H-H., Monni, O., Kokkola, A. J., Haglund, C., Petrova, T. & Ristimäki, A., 2009, In : Clinical Cancer Research. 15, 14, p. 4572-4580 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2008

Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer

Heinonen, H., Nieminen, A., Saarela, M., Kallioniemi, A., Klefström, J., Hautaniemi, S. & Monni, O., 2008, In : BMC Genomics. 9, 348, p. 1-12 12 p.

Research output: Contribution to journalArticleScientificpeer-review

High-resolution copy number and gene expression microarray analyses of head and neck squamous cell carcinoma cell lines of tongue and larynx

Järvinen, A-K., Autio, R., Kilpinen, S., Saarela, M., Leivo, I., Grenman, R., Mäkitie, A. & Monni, O., 2008, In : Genes, Chromosomes & Cancer. 47, 6, p. 500-509 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Integrated gene copy number and expression microarray analysis of gastric cancer highlights potential target genes

Myllykangas, S., Junnila, S., Kokkola, A., Autio, R., Scheinin, I., Kiviluoto, T., Karjalainen-Lindsberg, M-L., Hollmen, J., Knuutila, S., Puolakkainen, P. & Monni, O., 2008, In : International Journal of Cancer. 123, 4, p. 817-825 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2006

Differential gene expression in non-malignant tumour microenvironment is associated with outcome in follicular lymphoma patients treated with rituximab and CHOP

Harjunpää, A., Taskinen, M., Nykter, M., Karjalainen-Lindsberg, M-L., Nyman, H., Monni, O., Hemmer, S., Yli-Harja, O., Hautaniemi, S., Meri, S. & Leppä, S., 2006, In : British Journal of Haematology. 135, 1, p. 33-42 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Identification of target genes in laryngeal squamous cell carcinoma by high-resolution copy number and gene expression microarray analyses

Järvinen, A-K., Autio, R., Haapa-Paananen, S., Wolf, M., Saarela, M., Grenman, R., Leivo, I., Kallioniemi, O., Mäkitie, A. A. & Monni, O., 2006, In : Oncogene. 2006, 52, p. 6997-7008 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Novel genomic aberrations in testicular germ cell tumors by array-CGH, and associated gene expression changes

Skotheim, R. I., Autio, R., Lind, G. E., Kraggerud, S. M., Andrews, P. W., Monni, O., Kallioniemi, O-P. & Lothe, R. A., 2006, In : Cellular Oncology. 28, 5-6, p. 315-326 12 p.

Research output: Contribution to journalArticleScientificpeer-review

2005

Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal development

Skotheim, R. I., Lind, G. E., Monni, O., Nesland, J. M., Abeler, V. M., Fossa, S. D., Duale, N., Brunborg, G., Kallioniemi, O-P., Andrews, P. W. & Lothe, R. A., 2005, In : Cancer Research. 65, 13, p. 5588-5598 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Gene amplifications in osteosarcoma: CGH microarray analysis

Atiye, J., Wolf, M., Kaur, S., Monni, O., Bohling, T., Kivioja, A., Tas, E., Serra, M., Tarkkanen, M. & Knuutila, S., 2005, In : Genes, Chromosomes & Cancer. 42, 2, p. 158-163 6 p.

Research output: Contribution to journalArticleScientificpeer-review

2004

Are data from different gene expression microarray platforms comparable?

Jarvinen, A. K., Hautaniemi, S., Edgren, H., Auvinen, P., Saarela, J., Kallioniemi, O. P. & Monni, O., 2004, In : Genomics. 83, p. 1164-1168 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Effects of Herceptin treatment on global gene expression patterns in HER2-amplified and nonamplified breast cancer cell lines

Kauraniemi, P., Hautaniemi, S., Autio, R., Astola, J., Monni, O., Elkahloun, A. & Kallioniemi, A., 2004, In : Oncogene. 23, p. 1010-1013 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Helicobacter pylori infection activates FOS and stress-response genes and alters expression of genes in gastric cancer-specific loci

Myllykangas, S., Monni, O., Nagy, B., Rautelin, H. & Knuutila, S., Aug 2004, In : Genes, Chromosomes & Cancer. 40, 4, p. 334-341 8 p.

Research output: Contribution to journalArticleScientificpeer-review

High-resolution analysis of gene copy number alterations in human prostate cancer using CGH on cDNA microarrays: Impact of copy number on gene expression

Wolf, M., Mousses, S., Hautaniemi, S., Karhu, R., Huusko, P., Allinen, M., Elkahloun, A., Monni, O., Chen, Y. D., Kallioniemi, A. & Kallioniemi, O. P., 2004, In : NeoPlasia. 6, p. 240-247 8 p.

Research output: Contribution to journalArticleScientificpeer-review

High-resolution genomic and expression profiling reveals 105 putative amplification target genes in pancreatic cancer

Mahlamaki, E. H., Kauraniemi, P., Monni, O., Wolf, M., Hautaniemi, S. & Kallioniemi, A., 2004, In : NeoPlasia. 6, p. 432-439 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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2003

A novel strategy for microarray quality control using Bayesian networks

Hautaniemi, S., Edgren, H., Vesanen, P., Wolf, M., Jarvinen, A. K., Yli-Harja, O., Astola, J., Kallioniemi, O. & Monni, O., 2003, In : Bioinformatics. 19, p. 2031-2038 8 p.

Research output: Contribution to journalArticleScientificpeer-review

2001

Comprehensive copy number and gene expression profiling of the 17q23 amplicon in human breast cancer

Monni, O., Barlund, M., Mousses, S., Kononen, J., Sauter, G., Heiskanen, M., Paavola, P., Avela, K., Chen, YD., Bittner, ML. & Kallioniemi, A., 8 May 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 10, p. 5711-5716 6 p.

Research output: Contribution to journalArticleScientificpeer-review

PPP2R1B gene in chronic lymphocytic leukemias and mantle cell lymphomas

Zhu, Y., Loukola, A., Monni, O., Kuokkanen, K., Franssila, K., Elonen, E., Vilpo, J., Joensuu, H., Kere, J., Aaltonen, L. & Knuutila, S., 2001, In : Leukemia. 2001, 41, p. 177-183 7 p.

Research output: Contribution to journalArticleScientificpeer-review

1998

Comparative genomic hybridization study on pooled DNAs from tumors of one clinical-pathological entity

Knuutila, S., Armengol, G., Bjorkqvist, AM., ElRifai, W., Larramendy, ML., Monni, O. & Szymanska, J., 1 Jan 1998, In : Cancer Genetics and Cytogenetics. 100, 1, p. 25-30 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Gain of 3q and deletion of 11q22 are frequent aberrations in mantle cell lymphoma

Monni, O., Räty, R., Elonen, E., Franssila, K., Teerenhovi, L., Joensuu, H. & Knuutila, S., Apr 1998, In : Genes, Chromosomes & Cancer. 21, 4, p. 298-307 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Identification and characterization of a new latent transforming growth factor-beta-binding protein, LTBP-4

Saharinen, J., Taipale, J., Monni, O. & Keski-Oja, J., 17 Jul 1998, In : Journal of Biological Chemistry. 273, 29, p. 18459-18469 11 p.

Research output: Contribution to journalArticleScientificpeer-review

1997

17q12-21 amplicon, a novel recurrent genetic change in intestinal type of gastric carcinoma: A comparative genomic hybridization study

Kokkola, A., Monni, O., Puolakkainen, P., Larramendy, ML., Victorzon, M., Nordling, S., Haapiainen, R., Kivilaakso, E. & Knuutila, S., Sep 1997, In : Genes, Chromosomes & Cancer. 20, 1, p. 38-43 6 p.

Research output: Contribution to journalArticleScientificpeer-review

BCL2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma

Monni, O., Joensuu, H., Franssila, K., Klefström, J., Alitalo, K. & Knuutila, S., 1997, In : Blood. 90, p. 1168-1174 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Comparative genomic hybridization analysis of chromosomal changes occurring during development of acquired resistance to cisplatin in human ovarian carcinoma cells

Wasenius, VM., Jekunen, A., Monni, O., Joensuu, H., Aebi, S., Howell, SB. & Knuutila, S., Apr 1997, In : Genes, Chromosomes & Cancer. 18, 4, p. 286-291 6 p.

Research output: Contribution to journalArticleScientificpeer-review

1996

DNA copy number changes in diffuse large B-cell lymphoma - Comparative genomic hybridization study

Monni, O., Joensuu, H., Franssila, K. & Knuutila, S., 15 Jun 1996, In : Blood. 87, 12, p. 5269-5278 10 p.

Research output: Contribution to journalArticleScientificpeer-review