Research Output per year
Personal profile
Education/Academic qualification
Pharmaceutical Biology, Docent (Adjunct professor), University of Helsinki
Pharmacy, PhD, University of Helsinki
Keywords
- 317 Pharmacy
- Drug discovery, bioactivity screening, antimicrobials
- 1183 Plant biology, microbiology, virology
- 1182 Biochemistry, cell and molecular biology
International and National Collaboration
Publications and projects within past five years.
Selected Publications 1999 2019
DPD-inspired discovery of novel LsrK kinase inhibitors: an opportunity to fight antimicrobial resistance
Stotani, S., Gatta, V., Medarametla, P., Padmanaban, M., Karawajzyk, A., Giordanetto, F., Tammela, P., Laitinen, T., Poso, A., Tzalis, D. & Collina, S., 14 Mar 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2720-2737 18 p.Research output: Contribution to journal › Article › Scientific › peer-review
α-Amino diphenyl phosphonates as novel inhibitors of Escherichia coli ClpP protease
Moreno-Cinos, C., Sassetti, E., Salado, I. G., Witt, G., Benramdane, S., Reinhardt, L., Cruz, C. D., Joossens, J., Van der Veken, P., Brötz-Oesterhelt, H., Tammela, P. S. M., Winterhalter, M., Gribbon, P., Windshügel, B. & Augustyns, K., 24 Jan 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 774-797 24 p.Research output: Contribution to journal › Article › Scientific › peer-review
Miniaturized whole-cell bacterial bioreporter assay for identification of quorum sensing interfering compounds
Ilina, P., Ma, X., Sintim, H. O. & Tammela, P. S. M., Nov 2018, In : Journal of Microbiological Methods. 154, p. 40-45 6 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
File
Defining conditions for biofilm inhibition and eradication assays for Gram-positive clinical reference strains
Cruz, C. D., Shah, S. & Tammela, P., 3 Nov 2018, In : BMC Microbiology. 18, 9 p., 173.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
File
Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors
Durcik, M., Tammela, P. S. M., Barančoková, M., Tomašič, T., Ilaš, J., Kikelj, D. & Zidar, N., 22 Jan 2018, In : ChemMedChem : chemistry enabling drug discovery.. 13, 2, p. 186-198 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
Marine alkaloid oroidin analogues with antiviral potential: a novel class of synthetic compounds targeting the cellular chaperone Hsp90
Lillsunde, K-E., Tomašič, T., Kikelj, D. & Tammela, P., Dec 2017, In : Chemical Biology and Drug Design (Print). 90, 6, p. 1147-1154 8 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
File
Analyzing user-generated online content for drug discovery: Development and use of MedCrawler
Helfenstein, A. & Tammela, P., 15 Apr 2017, In : Bioinformatics. 33, 8, p. 1205-1209 5 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
File
Large-scale bioprospecting of cyanobacteria, micro- and macroalgae from the Aegean Sea
Montalvao, S. I. G. H., Demirel, Z., Devi, P., Lombardi, V., Hongisto, V., Perälä, M., Hattara, J., Imamoglu, E., Shet Tilvi, S., Turan, G., Conk Dalay, M. & Tammela, P. S. M., 1 Mar 2016, In : New Biotechnology. 33, 3, p. 399-406 8 p.Research output: Contribution to journal › Article › Scientific › peer-review
Bioluminescent whole-cell reporter gene assays as screening tools in the identification of antimicrobial natural product extracts
Nybond, S. C. S., Karp, M., Yrjönen, T. J. & Tammela, P. S. M., May 2015, In : Journal of Microbiological Methods. 114, p. 54-56 3 p.Research output: Contribution to journal › Article › Scientific › peer-review
Acetate-Derived Metabolites from the Brown Alga Lobophora variegata
Gutiérrez-Cepeda, A., Fernández, J. J., Norte, M., Montalvão, S., Tammela, P. & Souto, M. L., Jul 2015, In : Journal of Natural Products. 78, 7, p. 1716-1722 7 p.Research output: Contribution to journal › Article › Scientific › peer-review
Integrated in vitro - in silico screening strategy for the discovery of antibacterial compounds
Nybond, S., Ghemtio, L., Nawrot, D., Karp, M., Xhaard, H. & Tammela, P., 2015, In : Assay and drug development technologies. 13, 1, p. 25-33 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
Selected Projects 2009 2023
RESET-ME: Restoring E. coli sensitivity for antibiotics by blocking TolC-mediated efflux
Tammela, P. S. M., Durante Cruz, C., Windshugel, B., Winterhalter, M., Jirgensons, A. & Ceccarelli, M.
01/04/2019 → 31/03/2022
Project: Research project › _Research
EU-OPENSCREEN
Virtanen, H., Wennerberg, J. K., Urtti, A. O. & Tammela, P. S. M.
01/11/2011 → …
Project: Other project
New antimicrobials against Gram-positive bacteria
Tammela, P. S. M. & Durante Cruz, C.
01/10/2016 → 30/09/2018
Project: Research project
Prizes
Albert Wuokko Award to Young Scientist
Päivi Sirpa Marjaana Tammela (Recipient), 17 Nov 2006
Prize: Prizes and awards
Selected Activities 1999 2018
Bioreporters in screening and characterization of novel antimicrobial agents against Gram-negative bacteria
Päivi Tammela (Speaker)6 Jun 2017
Activity: Talk or presentation types › Invited talk
Åbo Akademi (External organisation)
Päivi Tammela (Expert member)Aug 2016
Activity: Membership types › Membership or other role in review committee
INTEGRATE Summer School: HTS, Medicinal Chemistry and Cell Biology in the Discovery of New Drugs Active Against Resistant G-negative Bacteria
Päivi Tammela (Chair of organizing committee)7 Jun 2016 → 10 Jun 2016
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
NOVA PhD course "Chemical and Genomic Insight to Host-Microbe Symbiotic Interactions"
Päivi Tammela (Speaker: Keynote)27 May 2016
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Press / Media
Metsäteollisuuden sivuvirrat hyötykäyttöön: Creating Bioeconomy, Paperi ja Puu, 2013, 34-35
01/01/2013
1 media contribution
Press/Media: Press / Media
Equipment
Bioactivity screening unit
Päivi Sirpa Marjaana Tammela (Manager)
Faculty of PharmacyFacility/equipment: Equipment