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Personal profile

Education/Academic qualification

Pharmaceutical Biology, Docent (Adjunct professor), University of Helsinki

Pharmacy, PhD, University of Helsinki

Keywords

  • 317 Pharmacy
  • Drug discovery, bioactivity screening, antimicrobials
  • 1183 Plant biology, microbiology, virology
  • 1182 Biochemistry, cell and molecular biology

International and National Collaboration Publications and projects within past five years.

Selected Publications 1999 2019

DPD-inspired discovery of novel LsrK kinase inhibitors: an opportunity to fight antimicrobial resistance

Stotani, S., Gatta, V., Medarametla, P., Padmanaban, M., Karawajzyk, A., Giordanetto, F., Tammela, P., Laitinen, T., Poso, A., Tzalis, D. & Collina, S., 14 Mar 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2720-2737 18 p.

Research output: Contribution to journalArticleScientificpeer-review

α-Amino diphenyl phosphonates as novel inhibitors of Escherichia coli ClpP protease

Moreno-Cinos, C., Sassetti, E., Salado, I. G., Witt, G., Benramdane, S., Reinhardt, L., Cruz, C. D., Joossens, J., Van der Veken, P., Brötz-Oesterhelt, H., Tammela, P. S. M., Winterhalter, M., Gribbon, P., Windshügel, B. & Augustyns, K., 24 Jan 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 774-797 24 p.

Research output: Contribution to journalArticleScientificpeer-review

Miniaturized whole-cell bacterial bioreporter assay for identification of quorum sensing interfering compounds

Ilina, P., Ma, X., Sintim, H. O. & Tammela, P. S. M., Nov 2018, In : Journal of Microbiological Methods. 154, p. 40-45 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Defining conditions for biofilm inhibition and eradication assays for Gram-positive clinical reference strains

Cruz, C. D., Shah, S. & Tammela, P., 3 Nov 2018, In : BMC Microbiology. 18, 9 p., 173.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors

Durcik, M., Tammela, P. S. M., Barančoková, M., Tomašič, T., Ilaš, J., Kikelj, D. & Zidar, N., 22 Jan 2018, In : ChemMedChem : chemistry enabling drug discovery.. 13, 2, p. 186-198 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Marine alkaloid oroidin analogues with antiviral potential: a novel class of synthetic compounds targeting the cellular chaperone Hsp90

Lillsunde, K-E., Tomašič, T., Kikelj, D. & Tammela, P., Dec 2017, In : Chemical Biology and Drug Design (Print). 90, 6, p. 1147-1154 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Analyzing user-generated online content for drug discovery: Development and use of MedCrawler

Helfenstein, A. & Tammela, P., 15 Apr 2017, In : Bioinformatics. 33, 8, p. 1205-1209 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Large-scale bioprospecting of cyanobacteria, micro- and macroalgae from the Aegean Sea

Montalvao, S. I. G. H., Demirel, Z., Devi, P., Lombardi, V., Hongisto, V., Perälä, M., Hattara, J., Imamoglu, E., Shet Tilvi, S., Turan, G., Conk Dalay, M. & Tammela, P. S. M., 1 Mar 2016, In : New Biotechnology. 33, 3, p. 399-406 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Bioluminescent whole-cell reporter gene assays as screening tools in the identification of antimicrobial natural product extracts

Nybond, S. C. S., Karp, M., Yrjönen, T. J. & Tammela, P. S. M., May 2015, In : Journal of Microbiological Methods. 114, p. 54-56 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Acetate-Derived Metabolites from the Brown Alga Lobophora variegata

Gutiérrez-Cepeda, A., Fernández, J. J., Norte, M., Montalvão, S., Tammela, P. & Souto, M. L., Jul 2015, In : Journal of Natural Products. 78, 7, p. 1716-1722 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Integrated in vitro - in silico screening strategy for the discovery of antibacterial compounds

Nybond, S., Ghemtio, L., Nawrot, D., Karp, M., Xhaard, H. & Tammela, P., 2015, In : Assay and drug development technologies. 13, 1, p. 25-33 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Selected Projects 2009 2023

RESET-ME: Restoring E. coli sensitivity for antibiotics by blocking TolC-mediated efflux

Tammela, P. S. M., Durante Cruz, C., Windshugel, B., Winterhalter, M., Jirgensons, A. & Ceccarelli, M.

01/04/201931/03/2022

Project: Research project_Research

EU-OPENSCREEN

Virtanen, H., Wennerberg, J. K., Urtti, A. O. & Tammela, P. S. M.

01/11/2011 → …

Project: Other project

Prizes

Jack L. Beal Award

Päivi Sirpa Marjaana Tammela (Recipient), 14 Jul 2010

Prize: Prizes and awards

Albert Wuokko Award to Young Scientist

Päivi Sirpa Marjaana Tammela (Recipient), 17 Nov 2006

Prize: Prizes and awards

Selected Activities 1999 2018

Bioreporters in screening and characterization of novel antimicrobial agents against Gram-negative bacteria

Päivi Tammela (Speaker)
6 Jun 2017

Activity: Talk or presentation typesInvited talk

Åbo Akademi (External organisation)

Päivi Tammela (Expert member)
Aug 2016

Activity: Membership typesMembership or other role in review committee

INTEGRATE Summer School: HTS, Medicinal Chemistry and Cell Biology in the Discovery of New Drugs Active Against Resistant G-negative Bacteria

Päivi Tammela (Chair of organizing committee)
7 Jun 201610 Jun 2016

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

NOVA PhD course "Chemical and Genomic Insight to Host-Microbe Symbiotic Interactions"

Päivi Tammela (Speaker: Keynote)
27 May 2016

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Press / Media

Tonneittain tuohta

Päivi Sirpa Marjaana Tammela

18/06/2009

1 media contribution

Press/Media: Press / Media

Pohjatyötä uusien lääkkeiden hyväksi

Päivi Sirpa Marjaana Tammela

01/01/2007

1 media contribution

Press/Media: Press / Media

Radio interview

Päivi Sirpa Marjaana Tammela

05/04/2006

1 media contribution

Press/Media: Press / Media

Equipment