Research output per year
Research output per year
- 14 results
Search results
-
2024
Somatic mutations associate with clonal expansion of CD8+ T cells
Lundgren, S., Myllymäki, M., Järvinen, T., Keränen, M. A. I., Theodoropoulos, J., Smolander, J., Kim, D., Salmenniemi, U., Walldin, G., Savola, P., Kelkka, T., Rajala, H., Hellström-Lindberg, E., Itälä-Remes, M., Kankainen, M. & Mustjoki, S., 7 Jun 2024, In: Science Advances. 10, 23, 13 p., eadj0787.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2022
Anemian laboratoriotutkimusten valinnan ja tulkinnan tueksi interaktiivinen työkalu
Savola, P., 2022, In: Kliin lab : kliinisen laboratorioalan julkaisu : SKKY:n jäsenlehti.. 39, 4, p. 149-149 1 p.Research output: Contribution to journal › Article › Professional
Open Access -
Novel Ex Vivo DOAC Removal Methods Reduce Interference in Lupus Anticoagulant Testing
Savola, P., Lemponen, M., Joutsi-Korhonen, L. & Helin, T. A., Oct 2022, In: Diagnostics. 12, 10, 11 p., 2520.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
The spectrum of somatic mutations in large granular lymphocyte leukemia, rheumatoid arthritis, and Felty?s syndrome
Savola, P., Bhattacharya, D. & Huuhtanen, J., Jul 2022, In: Seminars in Hematology. 59, 3, p. 123-130 8 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2020
Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+T Lymphocyte Signature
Kelkka, T., Savola, P., Bhattacharya, D., Huuhtanen, J., Lönnberg, T., Kankainen, M., Paalanen, K., Tyster, M., Lepistö, M., Ellonen, P., Smolander, J., Eldfors, S., Yadav, B., Khan, S., Koivuniemi, R., Sjöwall, C., Elo, L. L., Lahdesmaki, H., Maeda, Y., Nishikawa, H., & 3 others, 19 Nov 2020, In: Frontiers in Immunology. 11, 12 p., 578848.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Klonaalinen hematopoieesi : syövän ja terveen solun rajapinnalla
Savola, P. & Myllymäki, M., 2020, In: Kliin lab : kliinisen laboratorioalan julkaisu : SKKY:n jäsenlehti.. 37, 6, p. 189-193 5 p.Research output: Contribution to journal › Article › Professional
Open Access -
Somatic mutations and T-cell clonality in patients with immunodeficiency
Savola, P., Martelius, T., Kankainen, M., Huuhtanen, J., Lundgren, S., Koski, Y., Eldfors, S., Kelkka, T., Keränen, M. A. I., Ellonen, P., Kovanen, P. E., Kytölä, S., Saarela, J., Lahdesmaki, H., Seppänen, M. R. J. & Mustjoki, S., Dec 2020, In: Haematologica. 105, 12, p. 2757-2768 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2019
A robust pipeline with high replication rate for detection of somatic variants in the adaptive immune system as a source of common genetic variation in autoimmune disease
Van Horebeek, L., Hilven, K., Mallants, K., Van Nieuwenhuijze, A., Kelkka, T., Savola, P., Mustjoki, S., Schlenner, S. M., Liston, A., Dubois, B. & Goris, A., 15 Apr 2019, In: Human Molecular Genetics. 28, 8, p. 1369-1380 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2018
Sex bias in MHC I-associated shaping of the adaptive immune system
Schneider-Hohendorf, T., Goerlich, D., Savola, P., Kelkka, T., Mustjoki, S., Gross, C. C., Owens, G. C., Klotz, L., Dornmair, K., Wiendl, H. & Schwab, N., 27 Feb 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 9, p. 2168-2173 6 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Somatic STAT3 mutations in Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia
Savola, P., Brück, O., Olson, T., Kelkka, T., Kauppi, M. J., Kovanen, P. E., Kytölä, S., Sokka-Isler, T., Loughran, T. P., Leirisalo-Repo, M. & Mustjoki, S., Feb 2018, In: Haematologica. 103, 2, p. 304-312 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2017
Dasatinib Changes Immune Cell Profiles Concomitant with Reduced Tumor Growth in Several Murine Solid Tumor Models
Hekim, C., Ilander, M., Yan, J., Michaud, E., Smykla, R., Vaha-Koskela, M., Savola, P., Tahtinen, S., Saikko, L., Hemminki, A., Kovanen, P. E., Porkka, K., Lee, F. Y. F. & Mustjoki, S., Feb 2017, In: Cancer immunology research. 5, 2, p. 157-169 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
Somaattiset mutaatiot nivelreumassa
Kelkka, T. & Savola, P., 2017, In: Kliin lab : kliinisen laboratorioalan julkaisu : SKKY:n jäsenlehti.. 34, 5, p. 101-104 4 p.Research output: Contribution to journal › Article › Professional
Open AccessFile -
Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis
Savola, P., Kelkka, T., Rajala, H. L., Kuuliala, A., Kuuliala, K., Eldfors, S., Ellonen, P., Lagstrom, S., Lepisto, M., Hannunen, T., Andersson, E. I., Khajuria, R. K., Jaatinen, T., Koivuniemi, R., Repo, H., Saarela, J., Porkka, K., Leirisalo-Repo, M. & Mustjoki, S., 21 Jun 2017, In: Nature Communications. 8, 14 p., 15869.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2016
Oncolytic Adenovirus Expressing Monoclonal Antibody Trastuzumab for Treatment of HER2-Positive Cancer
Liikanen, I., Tähtinen, S., Guse, K., Gutmann, T., Savola, P., Oksanen, M., Kanerva, A. & Hemminki, A., 1 Sept 2016, In: Molecular Cancer Therapeutics. 15, 9, p. 2259-2269 11 p.Research output: Contribution to journal › Article › Scientific › peer-review