Research output per year
Research output per year
- 12 results
Search results
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2024
Distinct molecular profiles and shared drug vulnerabilities in pancreatic metastases of renal cell carcinoma
Roos-Mattila, M., Kallio, P., Luck, T. J., Polso, M., Kumari, R., Mikkonen, P., Välimäki, K., Malmstedt, M., Ellonen, P., Pellinen, T., Heckman, C. A., Mustonen, H., Puolakkainen, P. A., Alitalo, K., Kallioniemi, O., Mirtti, T., Rannikko, A. S., Pietiäinen, V. M. & Seppänen, H. E., Dec 2024, In: Communications Biology. 7, 1, 18 p., 1355.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2023
Analysis of transcription factor and growth factor vulnerabilities in tumor development and treatment resistance
Kallio, P., 2023, Helsinki: Helsingin yliopisto. 75 p.Research output: Thesis › Doctoral Thesis › Collection of Articles
Open Access -
2022
PROX1 transcription factor controls rhabdomyosarcoma growth, stemness, myogenic properties and therapeutic targets
Gizaw, N. Y., Kallio, P., Punger, T., Gucciardo, E., Haglund, C., Böhling, T., Lehti, K., Sampo, M., Alitalo, K. & Kivelä, R., 6 Dec 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 49, 10 p., e2116220119.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
β-catenin plus PROX1 immunostaining stratifies disease progression and patient survival in neoadjuvant-treated pancreatic cancer
Eurola, A., Ristimäki, A., Mustonen, H., Nurmi, A.-M., Hagström, J., Kallio, P., Alitalo, K., Haglund, C. & Seppänen, H., 2022, In: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 44, 1, p. 69-84 16 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2021
Expression of R-Spondin 1 in Apc(Min/+) Mice Suppresses Growth of Intestinal Adenomas by Altering Wnt and Transforming Growth Factor Beta Signaling
Lähde, M., Heino, S., Högström, J., Kaijalainen, S., Anisimov, A., Flanagan, D., Kallio, P., Leppänen, V.-M., Ristimäki, A., Ritvos, O., Wu, K., Tammela, T., Hodder, M., Sansom, O. J. & Alitalo, K., 1 Jan 2021, In: Gastroenterology. 160, 1, p. 245-259 15 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2020
Blocking Angiopoietin-2 Promotes Vascular Damage and Growth Inhibition in Mouse Tumors Treated with Small Doses of Radiation
Kallio, P., Jokinen, E., Högström, J., Das, S., Heino, S., Lähde, M., Brodkin, J., Korhonen, E. A. & Alitalo, K., 15 Jun 2020, In: Cancer Research. 80, 12, p. 2639-2650 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2018
Transcription Factor PROX1 Suppresses Notch Pathway Activation via the Nucleosome Remodeling and Deacetylase Complex in Colorectal Cancer Stem-like Cells
Högström, J., Heino, S., Kallio, P., Lähde, M., Leppänen, V.-M., Balboa, D., Wiener, Z. & Alitalo, K., 15 Oct 2018, In: Cancer Research. 78, 20, p. 5820-5832 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2017
High PROX1 expression in gastric cancer predicts better survival
Laitinen, A., Bockelman, C., Hagstrom, J., Kokkola, A., Kallio, P. & Haglund, C., 30 Aug 2017, In: PLoS One. 12, 8, 10 p., 0183868.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2016
PROX1 and beta-catenin are prognostic markers in pancreatic ductal adenocarcinoma
Saukkonen, K., Hagstrom, J., Mustonen, H., Juuti, A., Nordling, S., Kallio, P., Alitalo, K., Seppanen, H. & Haglund, C., 13 Jul 2016, In: BMC Cancer. 16, 12 p., 472.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2015
PROX1 is involved in progression of rectal neuroendocrine tumors, NETs
Jernman, J., Kallio, P., Hagstrom, J., Valimaki, M. J., Haapasalo, H., Alitalo, K., Arola, J. & Haglund, C., Sept 2015, In: Virchows Archiv. 467, 3, p. 279-284 6 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2014
Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-beta
Wiener, Z., Band, A. M., Kallio, P., Högström, J., Hyvönen, V., Kaijalainen, S., Ritvos, O., Haglund, C., Kruuna, O., Robine, S., Louvard, D., Ben-Neriah, Y. & Alitalo, K., 27 May 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 21, p. E2229-E2236 8 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Prox1 Promotes Expansion of the Colorectal Cancer Stem Cell Population to Fuel Tumor Growth and Ischemia Resistance
Wiener, Z., Hogstrom, J., Hyvonen, V., Band, A. M., Kallio, P., Holopainen, T., Dufva, O., Haglund, C., Kruuna, O., Oliver, G., Ben-Neriah, Y. & Alitalo, K., 25 Sept 2014, In: Cell Reports. 8, 6, p. 1943-1956 14 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile