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  • PL 65 (Viikinkaari 1)

    00014

    Finland

19972018
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Personal profile

Curriculum vitae

Previous Research and Education Activities

 

November 2010                     PhD degree. Major subject – physiology; the thesis title is                               “Neuronal K-Cl Cotransporter : Transcriptional Mechanisms of KCC2 Gene Regulation”

 

2000-present time                 Research scientist, Institute of Biotechnology and Neuroscience Centre,    University Helsinki, Finland

 

March-July, 1999                 Visiting scientist, The Whitney Laboratory for Marine Bioscience,                     University  of Florida, Florida, USA

 

June 1998                              Graduated from the Moscow Institute of Physics and Technology (Russia) with a Master of Science degree in Physics and Engineering

 

1996-2000                              Undergraduate student and M.S. study, Molecular Basics of Differentiation and Development Laboratory, Institute of Molecular Biology, Moscow, Russia

 

September-October, 1997    Visiting scientist, The White Sea Biological Station, Kartesh Cape,  Chupa, Russia

 

1992-1998                              B.S. and M.S. in physics. Major subject – biophysics; Moscow Institute of Physics and Technology (State University), Moscow, Russia

 

Scientific Activities

 

September 17-19, 2007        From molecules to cognition: a tribute to Jean-Pierre Changeux, Meeting, Paris, France

 

September 19-22, 2005        Physiology and Pathology of Chloride Transporters and Channels  Meeting, Soria, Spain

 

May 25-26, 2004                  Bioinformatics Workshop on Transcriptional Regulation, Espoo, Finland

 

December 1-2, 2003             In silico identification of transcriptional regions-course, Espoo, Finland

Keywords

  • 3112 Neurosciences
  • chloride homeostasis
  • kcc2
  • 1184 Genetics, developmental biology, physiology
  • gaba inhibition
  • knock out
  • 1182 Biochemistry, cell and molecular biology
  • Optogenetiikka
  • transcription

International and National Collaboration Publications and projects within past five years.

Publications 1997 2018

Role of the K+-Cl- Cotransporter KCC2a Isoform in Mammalian Respiration at Birth

Dubois, C. J., Cardoit, L., Schwarz, V., Markkanen, M., Airaksinen, M. S., Uvarov, P., Simmers, J. & Thoby-Brisson, M., 2018, In : eNeuro. 5, 5, 14 p., UNSP e0264-18.2018.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

A kainate receptor subunit promotes the recycling of the neuron-specific K+-Cl- co-transporter KCC2 in hippocampal neurons

Pressey, J. C., Mahadevan, V., Khademullah, C. S., Dargaei, Z., Chevrier, J., Huang, M., Chauhan, A. K., Meas, S. J., Uvarov, P., Airaksinen, M. S. & Woodin, M. A., 14 Apr 2017, In : Journal of Biological Chemistry. 292, 15, p. 6190-6201 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

A noninvasive optical approach for assessing chloride extrusion activity of the K-Cl cotransporter KCC2 in neuronal cells

Ludwig, A., Rivera Baeza, C. & Uvarov, P., 31 Jan 2017, In : BMC Neuroscience. 18, 15 p., 23.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Implications of the N-terminal heterogeneity for the neuronal K-Cl cotransporter KCC2 function

Markkanen, M., Ludwig, A., Khirug, S., Pryazhnikov, E., Soni, S., Khirug, L., Delpire, E., Rivera, J., Airaksinen, M. S. & Uvarov, P., 2017, In : Brain Research . 1675, p. 87-101 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Native KCC2 interactome reveals PACSIN1 as a critical regulator of synaptic inhibition

Mahadevan, V., Khademullah, C. S., Dargaei, Z., Chevrier, J., Uvarov, P., Kwan, J., Bagshaw, R. D., Pawson, T., Emili, A., De Koninck, Y., Anggono, V., Airaksinen, M. & Woodin, M. A., 13 Oct 2017, In : eLife. 6, 34 p., 28270.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Activities 1997 2017

  • 12 Organisation and participation in conferences, workshops, courses, seminars
  • 3 Academic visit to other institution
  • 1 Peer review of manuscripts

Frontiers in Cellular Neuroscience (Journal)

Pavel Uvarov (Reviewer)
19 Dec 2017

Activity: Publication peer-review and editorial work typesPeer review of manuscripts

Optogenetic techniques in neuroscience

Pavel Uvarov (Member of organizing committee)
13 Apr 201517 Apr 2015

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Nordic Neuroscience Meeting

Pavel Uvarov (Poster Presentation)
10 Jun 201512 Jun 2015

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Optogenetic techniques in neuroscience

Pavel Uvarov (Member of organizing committee)
10 Feb 201415 Feb 2014

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

The Neurobiology of Synapses and their Dysfunction

Pavel Uvarov (Attendee)
13 Oct 201317 Oct 2013

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars