Research output per year
Research output per year
Personal profile
Research interests
Biology of hematologic malignancies, RNA biology, drug sensitivity, drug re-purposing, personalized medicine.
Fields of Science
- 3111 Biomedicine
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Dynamics of leukemic blast and immune cell populations in Acute Myeloid Leukemia
Adhikari, S., Sergeev, P., Ikonen, N., Suvela, M., Kuusanmäki, H., Kontro, M., Vähä-Koskela, M. & Heckman, C., 3 Nov 2025, p. 3490-3491. 2 p.Research output: Conference materials › Abstract › peer-review
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Efficacy of Melflufen in Patients with Relapsed/Refractory Multiple Myeloma and Mutated or Deleted TP53
Acs, K., Miettinen, J. J., Sergeev, P., Heckel, T., Diao, Y., Witt-Mulder, K., Thureson, M., Bischler, T., Huppunen, M.-E., Suvela, M., Obermüller, J., Munawar, U., Slipicevic, A., Bargou, R. C., Lehmann, F., Svensson Gelius, S. S., Norin, S., Schjesvold, F., Sonneveld, P. & Stühmer, T. & 1 others, , 23 Dec 2025, In: Experimental Hematology & Oncology. 14, 1, 6 p., 138.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Perturbing LSD1 and WNT rewires transcription to synergistically induce AML differentiation
Hosseini, A., Dhall, A., Ikonen, N., Sikora, N., Nguyen, S., Shen, Y., Amaral, M. L. J., Jiao, A., Wallner, F., Sergeev, P., Lim, Y., Yang, Y., Vick, B., Kawabata, K. C., Melnick, A., Vyas, P., Ren, B., Jeremias, I., Psaila, B. & Heckman, C. A. & 2 others, , 12 Jun 2025, In: Nature. 642, 8067, 40 p., 102651.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones
Ianevski, A., Nader, K., Driva, K., Senkowski, W., Bulanova, D., Moyano-Galceran, L., Ruokoranta, T., Kuusanmäki, H., Ikonen, N., Sergeev, P., Vähä-Koskela, M., Giri, A. K., Vähärautio, A., Kontro, M., Porkka, K., Pitkänen, E., Heckman, C. A., Wennerberg, K. & Aittokallio, T., Dec 2024, In: Nature Communications. 15, 1, 16 p., 8579.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Deep Immune Profiling of Multiple Myeloma at Diagnosis and under Lenalidomide Maintenance Therapy
Luoma, S., Sergeev, P., Javarappa, K. K., Öhman, T. J., Varjosalo, M., Säily, M., Anttila, P., Sankelo, M., Partanen, A., Nihtinen, A., Heckman, C. A. & Silvennoinen, R., 4 May 2023, In: Cancers. 15, 9, 15 p., 2604.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
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Pharmacological targeting of high-risk hematological malignancies
Heckman, C. (Project manager), Adhikari, S. (Participant), Ikonen, N. (Participant), Kumari, R. (Participant), Mendoza Ortiz, E. D. (Participant), Newman, R. G. D. (Participant), Olgac, E. J. (Participant), Sergeev, P. (Participant), Srivastava, A. (Participant), Tambe, M. (Participant), Tanoli, Z. (Participant) & Tsallos, D. (Participant)
01/09/2023 → 31/08/2027
Project: Research Council of Finland: Academy Project
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Caroline Heckman NIH subaward ISB
Heckman, C. (Project manager), Adhikari, S. (Participant), Kallio, S. J. (Participant), Kuusanmäki, H. (Participant), Miettinen, J. (Participant), Olgac, E. J. (Participant), Parsons, A. O. (Participant), Ruokoranta, T. (Participant), Saad, J. (Participant), Sergeev, P. (Participant) & Srivastava, A. (Participant)
National Institutes of Health (NIH) OFM
01/01/2023 → 31/12/2025
Project: Other funder