Photo of Pia Siljander
  • PL 56 (Viikinkaari 9)

    00014

    Finland

1991 …2019
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Publications 1991 2019

Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles

Clayton, A., Boilard, E., Buzas, E. I., Cheng, L., Falcón-Perez, J. M., Gardiner, C., Gustafson, D., Gualerzi, A., Hendrix, A., Hoffman, A., Jones, J., Lässer, C., Lawson, C., Lenassi, M., Nazarenko, I., O’Driscoll, L., Pink, R., Siljander, P. R-M., Soekmadji, C., Wauben, M. & 4 othersWelsh, J. A., Witwer, K., Zheng, L. & Nieuwland, R., 1 Dec 2019, In : Journal of Extracellular Vesicles. 8, 1, 5 p., 1647027.

Research output: Contribution to journalArticleScientific

Open Access
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Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules

Valkonen, S., Holopainen, M., Colas, R. A., Impola, U., Dalli, J., Käkelä, R., Siljander, P. R-M. & Laitinen, S., Aug 2019, In : Biochimica and Biophysica Acta. Molecular and Cell Biology of Lipids. 1864, 8, p. 1168-1182 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Metabolic signature of extracellular vesicles depends on the cell culture conditions

Palviainen, M., Saari, H., Kärkkäinen, O., Pekkinen, J., Auriola, S., Yliperttula, M., Puhka, M., Hanhineva, K. & Siljander, P. R-M., 1 Jan 2019, In : Journal of Extracellular Vesicles. 8, 1, 12 p., 1596669.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Platelet-Derived Extracellular Vesicles

Gasecka, A., Nieuwland, R. & Siljander, P., 28 Mar 2019, Platelets. Michelson, A., Cattaneo, M., Frelinger, A. & Newman, P. (eds.). 4 ed. Academic press, p. 401-416

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Verisolujen solunulkoiset vesikkelit

Siljander, P., Valkonen, S., Laitinen, S. & Kerkelä, E., Apr 2019, In : Duodecim. 135, 7, p. 663-671 9 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

2018
Open Access
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Extracellular vesicles derived from hypoxic colorectal cancer cells confer metastatic phenotype to non-metastatic cancer cells

Endzelins, E., Abols, A., Buss, A., Zandberga, E., Palviainen, M. J., Siljander, P. R-M. & Line, A., 28 Aug 2018, In : Anticancer Research. 38, 9, p. 5169-5147 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Thery, C., Witwer, K. W., Aikawa, E., Jose Alcaraz, M., Anderson, J. D., Andriantsitohaina, R., Antoniou, A., Arab, T., Archer, F., Atkin-Smith, G. K., Ayre, D. C., Bach, J-M., Bachurski, D., Baharvand, H., Balaj, L., Baldacchino, S., Bauer, N. N., Baxter, A. A., Bebawy, M., Beckham, C. & 362 othersZavec, A. B., Benmoussa, A., Berardi, A. C., Bergese, P., Bielska, E., Blenkiron, C., Bobis-Wozowicz, S., Boilard, E., Boireau, W., Bongiovanni, A., Borras, F. E., Bosch, S., Boulanger, C. M., Breakefield, X., Breglio, A. M., Brennan, M. A., Brigstock, D. R., Brisson, A., Broekman, M. L. D., Bromberg, J. F., Bryl-Gorecka, P., Buch, S., Buck, A. H., Burger, D., Busatto, S., Buschmann, D., Bussolati, B., Buzas, E., Byrd, J. B., Camussi, G., Carter, D. R. F., Caruso, S., Chamley, L. W., Chang, Y-T., Chaudhuri, A. D., Chen, C., Chen, S., Cheng, L., Chin, A. R., Clayton, A., Clerici, S. P., Cocks, A., Cocucci, E., Coffey, R. J., Cordeiro-da-Silva, A., Couch, Y., Coumans, F. A. W., Coyle, B., Crescitelli, R., Criado, M. F., D'Souza-Schorey, C., Das, S., de Candia, P., De Santana Junior, E. F., De Wever, O., del Portillo, H. A., Demaret, T., Deville, S., Devitt, A., Dhondt, B., Di Vizio, D., Dieterich, L. C., Dolo, V., Dominguez Rubio, A. P., Dominici, M., Dourado, M. R., Driedonks, T. A. P., Duarte, F., Duncan, H. M., Eichenberger, R. M., Ekstrom, K., Andaloussi, S. E. L., Elie-Caille, C., Erdbrugger, U., Falcon-Perez, J. M., Fatima, F., Fish, J. E., Flores-Bellver, M., Forsonits, A., Frelet-Barrand, A., Fricke, F., Fuhrmann, G., Gabrielsson, S., Gamez-Valero, A., Gardiner, C., Gaertner, K., Gaudin, R., Gho, Y. S., Giebel, B., Gilbert, C., Gimona, M., Giusti, I., Goberdhan, D. C., Goergens, A., Gorski, S. M., Greening, D. W., Gross, J. C., Gualerzi, A., Gupta, G. N., Gustafson, D., Handberg, A., Haraszti, R. A., Harrison, P., Hegyesi, H., Hendrix, A., Hill, A. F., Hochberg, F. H., Hoffmann, K. F., Holder, B., Holthofer, H., Hosseinkhani, B., Hu, G., Huang, Y., Huber, V., Hunt, S., Ibrahim, A. G-E., Ikezu, T., Inal, J. M., Isin, M., Ivanova, A., Jackson, H. K., Jacobsen, S., Jay, S. M., Jayachandran, M., Jenster, G., Jiang, L., Johnson, S. M., Jones, J. C., Jong, A., Jovanovic-Talisman, T., Jung, S., Kalluri, R., Kano, S., Kaur, S., Kawamura, Y., Keller, E. T., Khamari, D., Khomyakova, E., Khvorova, A., Kierulf, P., Kim, K. P., Kislinger, T., Klingeborn, M., Klinke, D. J., Kornek, M., Kosanovic, M. M., Kovacs, A. F., Kraemer-Albers, E-M., Krasemann, S., Krause, M., Kurochkin, I., Kusuma, G. D., Kuypers, S., Laitinen, S., Langevin, S. M., Languino, L. R., Lannigan, J., Lasser, C., Laurent, L. C., Lavieu, G., Lazaro-Ibanez, E., Le Lay, S., Lee, M-S., Lee, Y. X. F., Lemos, D. S., Lenassi, M., Leszczynska, A., Li, I. T. S., Liao, K., Libregts, S. F., Ligeti, E., Lim, R., Lim, S. K., Line, A., Linnemannstoens, K., Llorente, A., Lombard, C. A., Lorenowicz, M. J., Lorincz, A. M., Lotvall, J., Lovett, J., Lowry, M. C., Loyer, X., Lu, Q., Lukomska, B., Lunavat, T. R., Maas, S. L. N., Malhi, H., Marcilla, A., Mariani, J., Mariscal, J., Martens-Uzunova, E. S., Martin-Jaular, L., Martinez, M. C., Martins, V. R., Mathieu, M., Mathivanan, S., Maugeri, M., McGinnis, L. K., McVey, M. J., Meckes, D. G., Meehan, K. L., Mertens, I., Minciacchi, V. R., Moller, A., Jorgensen, M. M., Morales-Kastresana, A., Morhayim, J., Mullier, F., Muraca, M., Musante, L., Mussack, V., Muth, D. C., Myburgh, K. H., Najrana, T., Nawaz, M., Nazarenko, I., Nejsum, P., Neri, C., Neri, T., Nieuwland, R., Nimrichter, L., Nolan, J. P., Hoen, E. N. M. N., Hooten, N. N., O'Driscoll, L., O'Grady, T., O'Loghlen, A., Ochiya, T., Olivier, M., Ortiz, A., Ortiz, L. A., Osteikoetxea, X., Ostegaard, O., Ostrowski, M., Park, J., Pegtel, D. M., Peinado, H., Perut, F., Pfaffl, M. W., Phinney, D. G., Pieters, B. C. H., Pink, R. C., Pisetsky, D. S., von Strandmann, E. P., Polakovicova, I., Poon, I. K. H., Powell, B. H., Prada, I., Pulliam, L., Quesenberry, P., Radeghieri, A., Raffai, R. L., Raimondo, S., Rak, J., Ramirez, M., Raposo, G., Rayyan, M. S., Regev-Rudzki, N., Ricklefs, F. L., Robbins, P. D., Roberts, D. D., Rodrigues, S. C., Rohde, E., Rome, S., Rouschop, K. M. A., Rughetti, A., Russell, A. E., Saa, P., Sahoo, S., Salas-Huenuleo, E., Sanchez, C., Saugstad, J. A., Saul, M. J., Schiffelers, R. M., Schneider, R., Schoyen, T. H., Scott, A., Shahaj, E., Sharma, S., Shatnyeva, O., Shekari, F., Shelke, G. V., Shetty, A. K., Shiba, K., Siljander, P. R-M., Silva, A. M., Skowronek, A., Snyder, O. L., Soares, R. P., Sodar, B. W., Soekmadji, C., Sotillo, J., Stahl, P. D., Stoorvogel, W., Stott, S. L., Strasser, E. F., Swift, S., Tahara, H., Tewari, M., Timms, K., Tiwari, S., Tixeira, R., Tkach, M., Toh, W. S., Tomasini, R., Torrecilhas, A. C., Pablo Tosar, J., Toxavidis, V., Urbanelli, L., Vader, P., van Balkom, B. W. M., van der Grein, S. G., Van Deun, J., van Herwijnen, M. J. C., Van Keuren-Jensen, K., van Niel, G., van Royen, M. E., van Wijnen, A. J., Helena Vasconcelos, M., Vechetti, I. J., Veit, T. D., Vella, L. J., Velot, E., Verweij, F. J., Vestad, B., Vinas, J. L., Visnovitz, T., Vukman, K. V., Wahlgren, J., Watson, D. C., Wauben, M. H. M., Weaver, A., Webber, J. P., Weber, V., Wehman, A. M., Weiss, D. J., Welsh, J. A., Wendt, S., Wheelock, A. M., Wiener, Z., Witte, L., Wolfram, J., Xagorari, A., Xander, P., Xu, J., Yan, X., Yanez-Mo, M., Yin, H., Yuana, Y., Zappulli, V., Zarubova, J., Zekas, V., Zhang, J., Zhao, Z., Zheng, L., Zheutlin, A. R., Zickler, A. M., Zimmermann, P., Zivkovic, A. M., Zocco, D. & Zuba-Surma, E. K., 23 Nov 2018, In : Journal of Extracellular Vesicles. 7, 1, 43 p., 1535750.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Phospholipid composition of packed red blood cells and that of extracellular vesicles show a high resemblance and stability during storage

Lauren, E., Tigistu-Sahle, F., Valkonen, S., Westberg, M., Valkeajarvi, A., Eronen, J., Siljander, P., Pettila, V., Kakela, R., Laitinen, S. & Kerkela, E., Jan 2018, In : Biochimica and Biophysica Acta. Molecular and Cell Biology of Lipids. 1863, 1, p. 1-8 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2017

Biological reference materials for extracellular vesicle studies

Valkonen, S., Pol, E. V. D., Böing, A., Yuana, Y., Yliperttula, M., Nieuwland, R., Laitinen, S. & Siljander, P. R-M., 2017, In : European Journal of Pharmaceutics and Biopharmaceutics. 98, p. 4-16 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Distinct prostate cancer-related mRNA cargo in extracellular vesicle subsets from prostate cell lines

Lazaro-Ibanez, E., Lunavat, T. R., Jang, S. C., Escobedo-Lucea, C., Oliver-De La Cruz, J., Siljander, P., Lotvall, J. & Yliperttula, M., 1 Feb 2017, In : BMC Cancer. 17, 11 p., 92.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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European Network on Microvesicles and Exosomes in Health and Disease (ME-HaD)

O'Driscoll, L., Stoorvogel, W., Thery, C., Buzas, E., Nazarenko, I., Siljander, P. R-M., Yanez-Mo, M., Fais, S., Giebel, B. & Yliperttula, M. L., 15 Feb 2017, In : European Journal of Pharmaceutical Sciences. 98, p. 1-3 3 p.

Research output: Contribution to journalArticleScientific

Isolation of Platelet-Derived Extracellular Vesicles

Aatonen, M., Valkonen, S., Boing, A., Yuana, Y., Nieuwland, R. & Siljander, P., 2017, Exosomes and Microvesicle: Methods and Protocols, Methods in Molecular Biology. Springer , Vol. 1545. p. 177-188 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapterScientific

KeepEX, a simple dilution protocol for improving extracellular vesicle yields from urine

Puhka, M., Nordberg, M. E., Valkonen, S., Rannikko, A., Kallioniemi, O., Siljander, P. & Hällström, T. M. A., 15 Feb 2017, In : European Journal of Pharmaceutical Sciences. 98, p. 30-39 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Metastatic state of parent cells influences the uptake and functionality of prostate cancer cell-derived extracellular vesicles

Lazaro Ibañez, E., Neuvonen, K. M., Takatalo-Laine, S. M., Thanigai Arasu, U., Capasso, C., Cerullo, V., Rhim, J., Rilla, K., Yliperttula, M. L. & Siljander, P. R-M., 10 Aug 2017, In : Journal of Extracellular Vesicles.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Methodological Guidelines to Study Extracellular Vesicles

Coumans, F. A. W., Brisson, A. R., Buzas, E. I., Dignat-George, F., Drees, E. E. E., El-Andaloussi, S., Emanueli, C., Gasecka, A., Hendrix, A., Hill, A. F., Lacroix, R., Lee, Y., van Leeuwen, T. G., Mackman, N., Maeger, I., Nolan, J. P., van der Pol, E., Pegtel, D. M., Sahoo, S., Siljander, P. R. M. & 3 othersSturk, G., de Wever, O. & Nieuwland, R., 12 May 2017, In : Circulation Research. 120, 10, p. 1632-1648 17 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access

Solunulkoiset vesikkelit - isoja asioita pienessä paketissa

Mari, P., Valkonen, S., Lindelöf, A., Puhka, M. & Siljander, P., 2017, In : Kliin lab : kliinisen laboratorioalan julkaisu : SKKY:n jäsenlehti.. 34, 4, p. 75-79 5 p.

Research output: Contribution to journalArticleProfessional

Uptake and functionality of prostate cancer extracellular vesicles depends on the metastatic stage of the parent cells

Lazaro Ibanez, E., Neuvonen, K. M., Takatalo-Laine, S. M., Thanigai Arasu, U., Capasso, C., Rhim, J., Rilla, K., Yliperttula, M. L. & Siljander, P. R-M., May 2017, In : Journal of Extracellular Vesicles. 6, sup1

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
2016

Adenosinergic Immunosuppression by Human Mesenchymal Stromal Cells Requires Co-Operation with T cells

Kerkelä, E., Laitinen, A., Räbinä, J., Valkonen, S., Takatalo, M., Larjo, A., Veijola, J., Lampinen, M., Siljander, P., Lehenkari, P., Alfthan, K. & Laitinen, S., Mar 2016, In : Stem Cells. 34, 3, p. 781-790 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine

Fais, S., O'Driscoll, L., Borras, F. E., Buzas, E., Camussi, G., Cappello, F., Carvalho, J., da Silva, A. C., Del Portillo, H., El Andaloussi, S., Trcek, T. F., Furlan, R., Hendrix, A., Gursel, I., Kralj-Iglic, V., Kaeffer, B., Kosanovic, M., Lekka, M. E., Lipps, G., Logozzi, M. & 17 othersMarcilla, A., Sammar, M., Llorente, A., Nazarenko, I., Oliveira, C., Pocsfalvi, G., Rajendran, L., Raposo, G., Rohde, E., Siljander, P., van Niel, G., Vasconcelos, M. H., Yanez-Mo, M., Yliperttula, M. L., Zarovni, N., Zavec, A. B. & Giebel, B., Apr 2016, In : ACS Nano. 10, 4, p. 3886-3899 14 p.

Research output: Contribution to journalArticleScientificpeer-review

First In Vivo Detection and Characterization of Hyaluronan-Coated Extracellular Vesicles in Human Synovial Fluid

Mustonen, A-M., Nieminen, P., Joukainen, A., Jaroma, A., Kääriäinen, T., Kröger, H., Lazaro-Ibanez, E., Siljander, P. R-M., Kärjä, V., Härkönen, K., Koistinen, A. & Rilla, K., Nov 2016, In : Journal of Orthopaedic Research. 34, 11, p. 1960-1968 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2015

Biological properties of extracellular vesicles and their physiological functions

described in "additional information", 14 May 2015, In : Journal of Extracellular Vesicles. 4, 60 p., 27066.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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EVpedia: a community web portal for extracellular vesicles research

Kim, D-K., Lee, J., Kim, S. R., Choi, D-S., Yoon, Y. J., Kim, J. H., Go, G., Nhung, D., Hong, K., Jang, S. C., Kim, S-H., Park, K-S., Kim, O. Y., Park, H. T., Seo, J. H., Aikawa, E., Baj-Krzyworzeka, M., van Balkom, B. W. M., Belting, M., Blanc, L. & 75 othersBond, V., Bongiovanni, A., Borras, F. E., Buee, L., Buzas, E. I., Cheng, L., Clayton, A., Cocucci, E., Dela Cruz, C. S., Desiderio, D. M., Di Vizio, D., Ekstrom, K., Falcon-Perez, J. M., Gardiner, C., Giebel, B., Greening, D. W., Gross, J. C., Gupta, D., Hendrix, A., Hill, A. F., Hill, M. M., Hoen, E. N., Hwang, D. W., Inal, J., Jagannadham, M. V., Jayachandran, M., Jee, Y-K., Jorgensen, M., Kim, K. P., Kim, Y-K., Kislinger, T., Lasser, C., Lee, D. S., Lee, H., van Leeuwen, J., Lener, T., Liu, M-L., Lotvall, J., Marcilla, A., Mathivanan, S., Moeller, A., Morhayim, J., Mullier, F., Nazarenko, I., Nieuwland, R., Nunes, D. N., Pang, K., Park, J., Patel, T., Pocsfalvi, G., del Portillo, H., Putz, U., Ramirez, M. I., Rodrigues, M. L., Roh, T-Y., Royo, F., Sahoo, S., Schiffelers, R., Sharma, S., Siljander, P., Simpson, R. J., Soekmadji, C., Stahl, P., Stensballe, A., Stepien, E., Tahara, H., Trummer, A., Valadi, H., Vella, L. J., Wai, S. N., Witwer, K., Yanez-Mo, M., Youn, H., Zeidler, R. & Gho, Y. S., 15 Mar 2015, In : Bioinformatics. 31, 6, p. 933-939 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Microvesicle- and exosome- mediated drug delivery enhances the cytotoxicity of Paclitaxel in autologous prostate cancer cells

Saari, H., Lazaro Ibanez, E., Viitala, T., Vuorimaa-Laukkanen, E., Siljander, P. & Yliperttula, M., 24 Sep 2015, In : Journal of Controlled Release. 220, p. 727-737 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2014

Different gDNA content in the subpopulations of Prostate Cancer Extracellular Vesicles: Apoptotic bodies, Microvesicles and Exosomes

Lazaro Ibañez, E., Sanz Garcia, A., Visakorpi, T., Escobedo-Lucea, C., Siljander, P., Ayuso-Sacido, A. & Yliperttula, M., Oct 2014, In : Prostate. 74, 14, p. 1379-1390 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Isolation and characterization of platelet-derived extracellular vesicles

Aatonen, M., Öhman, T. J., Nyman, T., Laitinen, S., Grönholm, M. & Siljander, P., 6 Aug 2014, In : Journal of Extracellular Vesicles. 3, 2014, 15 p., 24692.

Research output: Contribution to journalArticleScientificpeer-review

Prostate cancer cell-derived extracellular vesicle subpopulations contain different gDNA fragments

Lazaro Ibanez, E., Sanz Garcia, A., Escobedo-Lucea, C., Siljander, P. R-M., Ayuso-Sacido, A. & Yliperttula, M. L., 2014, In : Journal of Extracellular Vesicles. 3, 24214, p. 80 P4A-178.

Research output: Contribution to journalConference articleScientific

2013

Extracellular membrane vesicles from umbilical cord blood-derived MSC protect against ischemic acute kidney injury, a feature that is lost after inflammatory conditioning

Kilpinen, L., Impola, U., Sankkila, L., Ritamo, I., Aatonen, M., Kilpinen, S., Tuimala, J., Valmu, L., Levijoki, J., Finckenberg, P. M., Siljander, P., Kankuri, E., Mervaala, E. & Laitinen, S., 10 Dec 2013, In : Journal of Extracellular Vesicles. 2, 15 p., 21927.

Research output: Contribution to journalArticleScientificpeer-review

Properties of platelet-derived microvesicles depend on the activation pathway

Aatonen, M., Grönholm, M., Lopez-Contreraz, D. & Siljander, P., 2013, In : Journal of Extracellular Vesicles. 2

Research output: Contribution to journalConference articleScientificpeer-review

The activation pathway determines the properties of platelet-derived microvesicles

Aatonen, M., Grönholm, M., Lopez-Contreraz, D. & Siljander, P., 2013, In : Journal of thrombosis and haemostasis. 11, Supplement 2, p. 22 1 p.

Research output: Contribution to journalConference articleScientificpeer-review

2012

Platelet-Derived Microvesicles: Multitalented Participants in Intercellular Communication

Aatonen, M., Grönholm, M. & Siljander, P., 2012, In : Seminars in Thrombosis and Hemostasis. 38, 1, p. 102-113 12 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation

Kalra, H., Simpson, R. J., Ji, H., Aikawa, E., Altevogt, P., Askenase, P., Bond, V. C., Borràs, F. E., Breakefield, X., Budnik, V., Buzas, E., Camussi, G., Clayton, A., Cocucci, E., Falcon-Perez, J. M., Gabrielsson, S., Song Gho, Y., Gupta, D., Harsha, H. C., Hendrix, A. & 36 othersHill, A. F., Inal, J. M., Jenster, G., Krämer-Albers, E-M., Kiang Lim, S., Llorente, A., Lötvall, J., Marcilla, A., Mincheva-Nilsson, L., Nazarenko, I., Nieuwland, R., Nolte-´t Hoen, E. N. M., Pandey, A., Patel, T., Piper, M. G., Pluchino, S., Prasad, T. S. K., Rajendran, L., Raposo, G., Record, M., Reid, G. E., Sánchez-Madrid, F., Schiffelers, R. M., Siljander, P., Stensballe, A., Stoorvogel, W., Taylor, D., Thery, C., Valadi, H., van Balkom, B. W. M., Vázquez, J., Vidal, M., Wauben, M. H. M., Yáñez-Mó, M., Zoeller, M. & Mathivanan, S., 18 Dec 2012, In : PLoS Biology. 10, 12, p. e1001450 5 p.

Research output: Contribution to journalArticleScientificpeer-review

2011

Novel methodology in the characterization of platelet-derived microvesicles

Siljander, P., Aatonen, M. & Grönholm, M., 2011, In : Journal of thrombosis and haemostasis. 9, Supplement 2, p. 183-184 2 p.

Research output: Contribution to journalConference articleScientificpeer-review

Platelet-derived microparticles – an updated perspective

Siljander, P., 2011, In : Thrombosis Research. 127, Suppl.2, p. s30-s33 4 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

2008

Collagen-mimetic peptides mediate flow-dependent thrombus formation by high- or low-affinity binding of integrin alpha 2 beta 1 and glycoprotein VI

Munnix, I. C. A., Gilio, K., Siljander, P. R. M., Raynal, N., Feijge, M. A. H., Hackeng, T. M., Deckmyn, H., Smethurst, P. A., Farndale, R. W. & Heemskerk, J. W. M., 2008, In : Journal of thrombosis and haemostasis. 6, p. 2132-2142 11 p.

Research output: Contribution to journalArticleScientificpeer-review

2007

Flow-induced thrombus formation on immobilized collagen receptor-binding peptides

Munnix, I. C. A., Gilio, K., Raynal, N., Feijge, M. A. H., Fletcher, J., Siljander, P., Farndale, R. W. & Heemskerk, J. W. M., 2007, Unknown host publication.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Generation of intermediate affinity forms of α2 I domain

Hamaia, S. W., Siljander, P., Orf, K., Bihan, D., Williams, J., Raynal, N. & Farndale, R. W., 2007, Unknown host publication.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Platelet receptor recognition and cross-talk in collagen-induced activation of platelets

Farndale, R. W., Slatter, D. A., Siljander, P. R. -M. & Jarvis, G. E., 2007, In : Journal of thrombosis and haemostasis. 5, p. 220-229 10 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

2006

Use of synthetic peptides to locate novel integrin alpha(2)beta(1)-binding motifs in human collagen III

Raynal, N., Hamaia, S. W., Siljander, P. R. M., Maddox, B., Peachey, A. R., Fernandez, R., Foley, L. J., Slatter, D. A., Jarvis, G. E. & Farndale, R. W., 2006, In : Journal of Biological Chemistry. 281, p. 3821-3831 11 p.

Research output: Contribution to journalArticleScientificpeer-review

2005

Functional evidence for three activation states for platelet α2β1 integrin

Siljander, P., Smerling, C., Schoolmester, A., Hamia, S., Deckmyn, H. & Farndale, R., 2005, Unknown host publication.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Platelet collagen receptors and coagulation: A characteristic platelet response as possible target for antithrombotic treatment

Heemskerk, J. W. M., Kuijpers, M. J. E., Munnix, I. C. A. & Siljander, P. R. M., 2005, In : Trends in Cardiovascular Medicine. 15, p. 86-92 7 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

2004

Integrin activation state determines selectivity for novel recognition sites in fibrillar collagens

Siljander, P., Hamaia, S., Peachey, A. R., Slatter, D. A., Smethurst, P. A., Ouwehand, W. H., Knight, C. G. & Farndale, R. W., 2004, In : Journal of Biological Chemistry. 279, p. 47763-47772 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood

Siljander, P., Siljander, P. R. M., Munnix, I. C. A., Smethurst, P. A., Deckmyn, H., Lindhout, T., Ouwehand, W. H., Farndale, R. W. & Heemskerk, J. W. M., 2004, In : Blood. 103, p. 1333-1341 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2003

Collagen-induced platelet activation

Farndale, R. & Siljander, P., 2003, Thrombosis: Fundamental and Clinical Aspects. Leuven University Press, p. 49-73

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

2002

Platelet receptors:collagen

Siljander, P. & Farndale, R., 2002, Platelets in Thrombotic and Non-Thrombotic Disorders: Pathophysiology, Pahrmacology and Therapeutics. Cambridge University Press, p. 158-178

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

2001

Platelet adhesion enhances the glycoprotein VI-dependent procoagulant response - Involvement of p38 MAP kinase and calpain

Siljander, P., Farndale, R. W., Feijge, M. A. H., Comfurius, P., Kos, S., Bevers, E. M. & Heemskerk, J. W. M., 2001, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 21, p. 618-627 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Procoagulant activity on platelets adhered to collagen or plasma clot

Ilveskero, S., Siljander, P. & Lassila, R., 2001, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 21, p. 628-635 8 p.

Research output: Contribution to journalArticleScientificpeer-review