Photo of Pirjo Laakkonen
  • PL 63 (Haartmaninkatu 8)

    00014

    Finland

1990 …2020

Research output per year

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Publications

2006

Characterization of the Rab8-specific membrane traffic route linked to protrusion formation

Hattula, K., Furuhjelm, J., Tikkanen, J., Tanhuanpää, K., Laakkonen, P. M. & Peränen, J., 2006, In : Journal of Cell Science. 119, p. 4866-4877 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Targeting tie-1 inhibits the growth of tumor xenografts as a monotherapy and has increased activity in combination with a VEGF inhibitor

Dransfield, D., Laakkonen, P., Jussila, M., Arulanandam, A., Huang, L., Devy, L., Chen, J., Chang, Q., Pazmany, C., Rookey, K., Viswanathan, M., Mullberg, J., Schaus, J., Schoonbroodt, S., Steukers, M., Ladner, R., Wood, C. & Alitalo, K., 2006, In : EJC supplements. 4, p. 34-34 1 p.

Research output: Contribution to journalConference articleScientific

2005

Identification of breast cancer metastasis and chronic myeloid leukemia-specific cell surface proteins

Karhemo, P., Goodison, S., Porkka, K. & Laakkonen, P., 2005, In : Molecular & Cellular Proteomics. 4, 8 Suppl. 1, p. S114-S114 1 p.

Research output: Contribution to journalArticleScientificpeer-review

Multivalent antibody materials and methods for VEGF/PDGF family of growth factors

Alitalo, K., Eriksson, U., Achen, M., Cregory Renner, C., Stacker, S., Li, H. & Laakkonen, P. M., 2005, Patent No. 2005087812

Research output: Patent

2004

Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells

Laakkonen, P., Akerman, M. E., Biliran, H., Yang, M., Ferrer, F., Karpanen, T., Hoffman, R. M. & Ruoslahti, E., 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, p. 9381-9386 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates

Kerjaschki, D., Regele, H. M., Moosberger, I., Nagy-Bojarski, K., Watschinger, B., Soleiman, A., Birner, P., Krieger, S., Hovorka, A., Silberhumer, G., Laakkonen, P., Petrova, T., Langer, B. & Raab, I., 2004, In : Journal of the American Society of Nephrology. 15, p. 603-612 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Molecules that selectively home to vasculature of premalignant or malignant lesions of the pancreas and other organs

Hanahan, D., Ruoslahti, E., Joyce, J. A. & Laakkonen, P. M., 2004, Patent No. 7598341

Research output: Patent

2003

Lymphatic microvessels in the rat remnant kidney model of renal fibrosis: Aminopeptidase P and podoplanin are discriminatory markers for endothelial cells of blood and lymphatic vessels

Matsui, K., Nagy-Bojarsky, K., Laakkonen, P., Krieger, S., Mechtler, K., Uchida, S., Geleff, S., Kang, D. H., Johnson, R. J. & Kerjaschki, D., 2003, In : Journal of the American Society of Nephrology. 14, p. 1981-1989 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels

Christian, S., Pilch, J., Akerman, M. E., Porkka, K., Laakkonen, P. & Ruoslahti, E., 2003, In : Journal of Cell Biology. 163, p. 871-878 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis

Joyce, J. A., Laakkonen, P., Bernasconi, M., Bergers, G., Ruoslahti, E. & Hanahan, D., 2003, In : Cancer Cell. 4, p. 393-403 11 p.

Research output: Contribution to journalArticleScientificpeer-review

2002

A fragment of the HMGN2 protein homes to the nuclei of tumor cells and tumor endothelial cells in vivo

Porkka, K., Laakkonen, P., Hoffman, J. A., Bernasconi, M. & Ruoslahti, E., 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, p. 7444-7449 6 p.

Research output: Contribution to journalArticleScientificpeer-review

A tumor-homing peptide with a targeting specificity related to lymphatic vessels

Laakkonen, P., Porkka, K., Hoffman, J. A. & Ruoslahti, E., 2002, In : Nature Medicine. 8, p. 751-755 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Nanocrystal targeting in vivo

Akerman, M. E., Chan, W. C. W., Laakkonen, P., Bhatia, S. N. & Ruoslahti, E., 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, p. 12617-12621 5 p.

Research output: Contribution to journalArticleScientificpeer-review

2001

Solution structures and integrin binding activities of an RGD peptide with two isomers

Assa-Munt, N., Jia, X., Laakkonen, P. & Ruoslahti, E., 2001, In : Biochemistry. 40, 8, p. 2373-2378 6 p.

Research output: Contribution to journalArticleScientificpeer-review

2000

Effects of palmitoylation of replicase protein nsP1 on alphavirus infection

Ahola, T., Kujala, P., Tuittila, M., Blom, T., Laakkonen, P., Hinkkanen, A. & Auvinen, P., 2000, In : Journal of Virology. 74, p. 6725-6733 9 p.

Research output: Contribution to journalArticleScientificpeer-review

1998

Alphavirus replicase protein NSP1 induces filopodia and rearrangement of actin filaments

Laakkonen, P., Auvinen, P., Kujala, P. & Kaariainen, L., 1998, In : Journal of Virology. 72, p. 10265-10269 5 p.

Research output: Contribution to journalArticleScientificpeer-review

1997

Critical residues of Semliki Forest virus RNA capping enzyme involved in methyltransferase and guanylyltransferase-like activities

Ahola, T., Laakkonen, P., Vihinen, H. & Kaariainen, L., 1997, In : Journal of Virology. 71, p. 392-397 6 p.

Research output: Contribution to journalArticleScientificpeer-review

1996

Synthesis of Semliki Forest virus RNA polymerase components nsP1 through nsP4 in Saccharomyces cerevisiae by expression of cDNA encoding the nonstructural polyprotein

Russo, P., Laakkonen, P., Ahola, T. & Kaariainen, L., 1996, In : Journal of Virology. 70, p. 4086-4089 4 p.

Research output: Contribution to journalArticleScientificpeer-review

The effects of palmitoylation on membrane association of Semliki Forest virus RNA capping enzyme

Laakkonen, P., Ahola, T. & Kaariainen, L., 1996, In : Journal of Biological Chemistry. 271, p. 28567-28571 5 p.

Research output: Contribution to journalArticleScientificpeer-review

1995

THE ALPHAVIRUS REPLICASE PROTEIN NSP1 IS MEMBRANE-ASSOCIATED AND HAS AFFINITY TO ENDOCYTIC ORGANELLES

PERANEN, J., LAAKKONEN, P., HYVONEN, M. & KAARIAINEN, L., 1995, In : Virology. 208, p. 610-620 11 p.

Research output: Contribution to journalArticleScientificpeer-review

1994

EXPRESSION OF SEMLIKI FOREST VIRUS NSP1-SPECIFIC METHYLTRANSFERASE IN INSECT CELLS AND IN ESCHERICHIA-COLI

LAAKKONEN, P., HYVONEN, M., PERANEN, J. & KAARIAINEN, L., 1994, In : Journal of Virology. 68, p. 7418-7425 8 p.

Research output: Contribution to journalArticleScientificpeer-review

1990

A SINGLE AMINO-ACID CHANGE IN E3 OF TS1 MUTANT INHIBITS THE INTRACELLULAR-TRANSPORT OF SFV ENVELOPE PROTEIN COMPLEX

Laakkonen, P. M., PERANEN, J., SUOMALAINEN, M., KERANEN, S. & KAARIAINEN, L., 1990, In : Virology. 179, p. 658-666 9 p.

Research output: Contribution to journalArticleScientificpeer-review