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Publications 1995 2019

2019

Analysis of steroids in urine by gas chromatography-capillary photoionization-tandem mass spectrometry

Pöhö, P., Scholz, K., Kärkkäinen, N., Haapala, M., Räikkönen, H., Kostiainen, R. & Vaikkinen, A., 2 Aug 2019, In : Journal of Chromatography. A. 1598, p. 175-182 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Capillary photoionization: interface for low flow rate liquid chromatography-mass spectrometry

Pöhö, P., Vaikkinen, A., Haapala, M., Kylli, P. & Kostiainen, R., 7 May 2019, In : Analyst. 144, 9, p. 2867-2871 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Open Access
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TiO2 Photocatalyzed Oxidation of Drugs Studied by Laser Ablation Electrospray Ionization Mass Spectrometry

van Geenen, F. A. M. G., Franssen, M. C. R., Miikkulainen, V., Ritala, M., Zuilhof, H., Kostiainen, R. & Nielen, M. W. F., Apr 2019, In : Journal of the American Society for Mass Spectrometry. 30, 4, p. 639-646 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2018

Advances in Optics and Integration Possibilities of 3D Printed Methacrylate Microdevices

Haapala, M. J., Nordman, N. M., Kostiainen, R. K. & Sikanen, T. M., 24 Sep 2018.

Research output: Conference materialsAbstractResearchpeer-review

Capillary Isoelectric Focusing on 3D Printed Methacrylate Microchips

Haapala, M. J., Nordman, N. M., Kostiainen, R. K. & Sikanen, T. M., 14 May 2018.

Research output: Conference materialsAbstractResearch

Combined transcriptomics, proteomics and metabolomics analysis identifies metabolic pathways associated with the loss of cardiac regeneration

Talman, V., Teppo, J., Poho, P., Movahedi, P., Vaikkinen, A., Pahikkala, T., Kotiaho, T., Kostiainen, R., Varjosalo, M. & Ruskoaho, H., Apr 2018, In : Cardiovascular Research. 114, p. S22-S23 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
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Impact of Pore Size and Surface Chemistry of Porous Silicon Particles and Structure of Phospholipids on Their Interactions

Liu, D., Lipponen, K., Quan, P., Wan, X., Zhan, H., Makilä, E., Salonen, J., Kostiainen, R., Hirvonen, J., Kotiaho, T. & Santos, H. A., Jul 2018, In : Acs Biomaterials Science & Engineering. 4, 7, p. 2308-2313 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Molecular Atlas of Postnatal Mouse Heart Development

Talman, V., Teppo, J. S., Pöhö, P. A., Movahedi, P., Vaikkinen, A., Karhu, S. T., Trošt, K., Suvitaival, T., Heikkonen, J., Pahikkala, T., Kotiaho, A. A. T., Kostiainen, R. K., Varjosalo, M. T. & Ruskoaho, H. J., 16 Oct 2018, In : Journal of the American Heart Association. 7, 20, 46 p., 010378.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2017

Ambient mass spectrometry in the analysis of compounds of low polarity

Kauppila, T. J. & Kostiainen, R., 14 Sep 2017, In : Analytical Methods. 9, 34, p. 4936-4953 18 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Analysis of morphine from mouse plasma by microchip electrophoresis-electrochemical detection

Ollikainen, A. E. K., Koburg, M., Aitta-aho, T. H. J., Kostiainen, R. K. & Sikanen, T. M., 22 Jun 2017.

Research output: Conference materialsPosterResearchpeer-review

Feasibility of ultra-performance liquid chromatography-ion mobility-time-of-flight mass spectrometry in analyzing oxysterols

Kylli, P., Hankemeier, T. & Kostiainen, R., 3 Mar 2017, In : Journal of Chromatography. A. 1487, p. 147-152 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Thiol-ene micropillar array electrospray ionization platform for zeptomole level bioanalysis

Lipponen, K., Tähkä, S., Sikanen, T., Jokinen, V., Tatikonda, A., Franssila, S., Kostiainen, R. & Kotiaho, T., 21 Jul 2017, In : Analyst. 142, 14, p. 2552-2557 6 p.

Research output: Contribution to journalArticleScientificpeer-review

TiO2 Photocatalysis-DESI-MS Rotating Array Platform for High-Throughput Investigation of Oxidation Reactions

Ruokolainen, M., Miikkulainen, V., Ritala, M., Sikanen, T., Kotiaho, T. & Kostiainen, R., 7 Nov 2017, In : Analytical Chemistry. 89, 21, p. 11214-11218 5 p.

Research output: Contribution to journalArticleScientificpeer-review

2016

Charge Exchange Reaction in Dopant-Assisted Atmospheric Pressure Chemical Ionization and Atmospheric Pressure Photoionization

Vaikkinen, A., Kauppila, T. J. & Kostiainen, R., Aug 2016, In : Journal of the American Society for Mass Spectrometry. 27, 8, p. 1291-1300 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Comparison of TiO2 photocatalysis, electrochemically assisted Fenton reaction and direct electrochemistry for simulation of phase I metabolism reactions of drugs

Ruokolainen, M., Gul, T., Permentier, H., Sikanen, T., Kostiainen, R. & Kotiaho, T., 15 Feb 2016, In : European Journal of Pharmaceutical Sciences. 83, p. 36-44 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Oxidation of Tyrosine-Phosphopeptides by Titanium Dioxide Photocatalysis

Ruokolainen, M., Ollikainen, E., Sikanen, T., Kotiaho, T. & Kostiainen, R., 22 Jun 2016, In : Journal of the American Chemical Society. 138, 24, p. 7452-7455 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Rapid separation of phosphopeptides by microchip electrophoresis-electrospray ionization mass spectrometry

Ollikainen, E., Bonabi, A., Nordman, N., Jokinen, V., Kotiaho, T., Kostiainen, R. & Sikanen, T., 1 Apr 2016, In : Journal of Chromatography. A. 1440, p. 249-254 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Thin layer chromatography/desorption atmospheric pressure photoionization Orbitrap mass spectrometry of lipids

Rejsek, J., Vrkoslav, V., Vaikkinen, A., Haapala, M., Kauppila, T. J., Kostiainen, R. & Cvacka, J., 2016, In : Analytical Chemistry. 88, 24, p. 12279-12286 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Visualization of Local "Hot Spots" During Isoelectric Focusing on Chip by IR Thermography

Nordman, N., Haapala, M. J., Kostiainen, R. & Sikanen, T. M., Nov 2016.

Research output: Conference materialsPosterResearchpeer-review

2015

Analysis of neonicotinoids from plant material by desorption atmospheric pressure photoionization-mass spectrometry

Vaikkinen, A., Schmidt, H. S., Kiiski, I., Rämö, S., Hakala, K., Haapala, M., Kostiainen, R. & Kauppila, T. J., 15 Mar 2015, In : Rapid Communications in Mass Spectrometry. 29, 5, p. 424-430 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Feasibility of desorption atmospheric pressure photoionization and desorption electrospray ionization mass spectrometry to monitor urinary steroid metabolites during pregnancy

Vaikkinen, A., Rejsek, J., Vrkoslav, V., Kauppila, T. J., Cvacka, J. & Kostiainen, R., 23 Jun 2015, In : Analytica Chimica Acta. 880, p. 84-92 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Interfacing microchip isoelectric focusing with on-chip electrospray ionization mass spectrometry

Nordman, N., Lauren, S., Kotiaho, T., Franssila, S., Kostiainen, R. & Sikanen, T., 12 Jun 2015, In : Journal of Chromatography. A. 1398, p. 121-126 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Permeation of Dopamine Sulfate through the Blood-Brain Barrier

Suominen, T., Piepponen, T. P. & Kostiainen, R., 24 Jul 2015, In : PLoS One. 10, 7, 13 p., 0133904.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Shape-anchored porous polymer monoliths for integrated online solid-phase extraction-microchip electrophoresis-electrospray ionization mass spectrometry

Nordman, N., Barrios-Lopez, B., Lauren, S., Suvanto, P., Kotiaho, T., Franssila, S., Kostiainen, R. & Sikanen, T., Feb 2015, In : Electrophoresis. 36, 3, p. 428-432 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Silicon micropillar electrospray ionization chip platform for biomolecular analysis in aqueous phase

Hirvonen, S., Lipponen, K. H., Jokinen, V., Sikanen, T. M., Franssila, S., Kostiainen, R. K. & Kotiaho, A. A. T., 2015, Proceedings of the 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Gyeongju: CBM Society, p. 1752-1754 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Solvent Jet Desorption Capillary Photoionization-Mass Spectrometry

Haapala, M., Teppo, J., Ollikainen, E., Kiiski, I., Vaikkinen, A., Kauppila, T. J. & Kostiainen, R., 17 Mar 2015, In : Analytical Chemistry. 87, 6, p. 3280-3285 6 p.

Research output: Contribution to journalArticleScientificpeer-review

The detection and mapping of the spatial distribution of insect defense compounds by desorption atmospheric pressure photoionization Orbitrap mass spectrometry

Rejsek, J., Vrkoslav, V., Hanus, R., Vaikkinen, A., Haapala, M., Kauppila, T. J., Kostiainen, R. & Cvacka, J., 30 Jul 2015, In : Analytica Chimica Acta. 886, p. 91-97 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Transmission mode desorption atmospheric pressure photoionization

Vaikkinen, A., Hannula, J., Kiiski, I., Kostiainen, R. & Kauppila, T. J., 15 Apr 2015, In : Rapid Communications in Mass Spectrometry. 29, 7, p. 585-592 8 p.

Research output: Contribution to journalArticleScientificpeer-review

2014

Analysis of oxysterols and vitamin D metabolites in mouse brain and cell line samples by ultra-high-performance liquid chromatography-atmospheric pressure photoionization-mass spectrometry

Ahonen, L., Maire, F. B. R., Savolainen, M., Kopra, J., Vreeken, R. J., Hankemeier, T., Myöhänen, T., Kylli, P. & Kostiainen, R., 17 Oct 2014, In : Journal of Chromatography. A. 1364, p. 214-222 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Are Clusters Important in Understanding the Mechanisms in Atmospheric Pressure Ionization? Part 1: Reagent Ion Generation and Chemical Control of Ion Populations

Klee, S., Derpmann, V., Wissdorf, W., Klopotowski, S., Kersten, H., Brockmann, K. J., Benter, T., Albrecht, S., Bruins, A. P., Dousty, F., Kauppila, T. J., Kostiainen, R., O'Brien, R., Robb, D. B. & Syage, J. A., Aug 2014, In : Journal of the American Society for Mass Spectrometry. 25, 8, p. 1310-1321 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Imitation of phase I oxidative metabolism of anabolic steroids by titanium dioxide photocatalysis

Ruokolainen, M., Valkonen, M., Sikanen, T., Kotiaho, T. & Kostiainen, R., 2014, In : European Journal of Pharmaceutical Sciences. 65, p. 45-55 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Laser ablation atmospheric pressure photoionization mass spectrometry imaging of phytochemicals from sage leaves

Vaikkinen, A., Shrestha, B., Koivisto, J., Kostiainen, R., Vertes, A. & Kauppila, T. J., 2014, In : Rapid Communications in Mass Spectrometry. 28, 23, p. 2490-2496 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Separation of nucleobases, nucleosides, and nucleotides using two zwitterionic silica-based monolithic capillary columns coupled with tandem mass spectrometry

Moravcova, D., Haapala, M., Planeta, J., Hyötyläinen, T., Kostiainen, R. & Wiedmer, S. K., 19 Dec 2014, In : Journal of Chromatography. A. 1373, p. 90-96 7 p.

Research output: Contribution to journalArticleScientificpeer-review

2013

Analysis of anabolic steroids in urine by gas chromatography-microchip atmospheric pressure photoionization-mass spectrometry with chlorobenzene as dopant

Hintikka, L., Haapala, M., Kuuranne, T., Leinonen, A. & Kostiainen, R., 18 Oct 2013, In : Journal of Chromatography. A. 1312, p. 111-117 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Capillary Photoionization: A High Sensitivity Ionization Method for Mass Spectrometry

Haapala, M., Suominen, T. & Kostiainen, R., 28 May 2013, In : Analytical Chemistry. 85, 12, p. 5715-5719 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Determination of Serotonin and Dopamine Metabolites in Human Brain Microdialysis and Cerebrospinal Fluid Samples by UPLC-MS/MS: Discovery of Intact Glucuronide and Sulfate Conjugates

Suominen, T., Uutela, P., Ketola, R. A., Bergquist, J., Hillered, L., Finel, M., Zhang, H., Laakso, A. & Kostiainen, R., 27 Jun 2013, In : PLoS One. 8, 6, 9 p., e68007.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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ELECTROOSMOTICALLY ACTUATED ON-CHIP SOLID-PHASE EXTRACTION WITH MICROCHIP ELECTRPHORESIS-ELECTROSPRAY IONIZATION MASS SPECTROMETRY

Nordman, N., Barrios-Lopez, B., Laurén, S., Suvanto, P., Kotiaho, T., Franssila, S., Kostiainen, R. & Sikanen, T., 2013, Unknown host publication. Chemical and Biological Microsystems Society, 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Neurosteroid analysis by gas chromatography-atmospheric pressure photoionization-tandem mass spectrometry

Suominen, T., Haapala, M., Takala, A., Ketola, R. A. & Kostiainen, R., 10 Sep 2013, In : Analytica Chimica Acta. 794, p. 76-81 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Separation of steroid isomers by ion mobility mass spectrometry

Ahonen, L., Fasciotti, M., Boije af Gennäs, G., Kotiaho, T., Daroda, R. J., Eberlin, M. & Kostiainen, R., 20 Aug 2013, In : Journal of Chromatography. A. 1310, p. 133-137 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Simultaneous Detection of Nonpolar and Polar Compounds by Heat-Assisted Laser Ablation Electrospray Ionization Mass Spectrometry

Vaikkinen, A., Shrestha, B., Nazarian, J., Kostiainen, R., Vertes, A. & Kauppila, T. J., 2013, In : Analytical Chemistry. 85, 1, p. 177-184

Research output: Contribution to journalArticleScientificpeer-review

Steroid and steroid glucuronide profiles in urine during pregnancy determined by liquid chromatography-electrospray ionization-tandem mass spectrometry

Jantti, S. E., Hartonen, M., Hilvo, M., Nygren, H., Hyotylainen, T., Ketola, R. A. & Kostiainen, R., 13 Nov 2013, In : Analytica Chimica Acta. 802, p. 56-66 11 p.

Research output: Contribution to journalArticleScientificpeer-review

2012

A microfabricated micropillar liquid chromatographic chip monolithically integrated with an electrospray ionization tip

Sainiemi, L., Nissilä, T., Kostiainen, R., Franssila, S. & Ketola, R. A., 2012, In : Lab on a Chip. 12, 2, p. 325-332 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Comparison of Direct and Alternating Current Vacuum Ultraviolet Lamps in Atmospheric Pressure Photoionization

Vaikkinen, A., Haapala, M., Kersten, H., Benter, T., Kostiainen, R. & Kauppila, T. J., 9 Jan 2012, In : Analytical Chemistry. 84, 3, p. 1408-1415 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Comparison of liquid chromatography-microchip/mass spectrometry to conventional liquid chromatography-mass spectrometry for the analysis of steroids

Ahonen, L., Keski-Rahkonen, P., Saarelainen, T., Paviala, J., Ketola, R. A., Auriola, S., Poutanen, M. & Kostiainen, R., 2012, In : Analytica Chimica Acta. 721, p. 115-121 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Desorption atmospheric pressure photoionization-mass spectrometry

Kauppila, T., Vaikkinen, A., Haapala, M., Suni, N., Kotiaho, T. & Kostiainen, R., 2012, Unknown host publication.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientific