Photo of Risto Kostiainen
  • PL 56 (Viikinkaari 5)

    00014

    Finland

19952019
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Publications 1995 2019

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Rapid and sensitive drug metabolism studies by SU-8 microchip capillary electrophoresis-electrospray ionization mass spectrometry

Nordman, N., Sikanen, T., Moilanen, M-E., Aura, S., Kotiaho, T., Franssila, S. & Kostiainen, R., 2011, In : Journal of Chromatography. A. 1218, 5, p. 739-745 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Spatial Distribution of Glycerophospholipids in the Ocular Lens

Pol, J., Vidova, V., Hyötyläinen, T., Volny, M., Novak, P., Strohalm, M., Kostiainen, R., Havlicek, V., Wiedmer, S. & Holopainen, J. M., 2011, In : PLoS One. 6, 4, p. e19441 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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2010

A high-resolution mass spectrometer to measure atmospheric ion composition

Junninen, H., Ehn, M., Petäjä, T., Luosujärvi, L., Kotiaho, T., Kostiainen, R., Rohner, U., Gonin, M., Fuhrer, K., Kulmala, M. & Worsnop, D. R., 2010, In : Atmospheric Measurement Techniques. 3, p. 1039-1053 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Analysis of Selective Androgen Receptor Modulators by Gas Chromatography-Microchip Atmospheric Pressure Photoionization-Mass Spectrometry

Luosujarvi, L., Haapala, M., Thevis, M., Saarela, V., Franssila, S., Ketola, R. A., Kostiainen, R. & Kotiaho, T., 2010, In : Journal of the American Society for Mass Spectrometry. 21, 2, p. 310-316 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Desorption Atmospheric Pressure Photoionization with PDMS as Extraction Phase and Sample Plate Material

Vaikkinen, A., Kotiaho, T., Kostiainen, R. & Kauppila, T., 2010, In : Analytica Chimica Acta. 682, 1-2, p. 1-8

Research output: Contribution to journalArticleScientificpeer-review

Determination of Steroids and Their Intact Glucuronide Conjugates in Mouse Brain by Capillary Liquid Chromatography-Tandem Mass Spectrometry

Jantti, S. E., Tammimaki, A., Raattamaa, H., Piepponen, P., Kostiainen, R. & Ketola, R. A., 2010, In : Analytical Chemistry. 82, p. 3168-3175 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Dynamic coating of SU-8 microfluidic chips with phospholipid disks

Sikanen, T., Wiedmer, S., Heikkilä, L., Franssila, S., Kostiainen, R. & Kotiaho, T., 2010, In : Electrophoresis. 31, 15, p. 2566-2574 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Environmental and food analysis by desorption atmospheric pressure photoionization-mass spectrometry

Luosujarvi, L., Kanerva, S., Saarela, V., Franssila, S., Kostiainen, R., Kotiaho, T. & Kauppila, T. J., 2010, In : Rapid Communications in Mass Spectrometry. 24, p. 1343-1350 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Fabrication of nanocluster silicon surface with electric discharge and the application in desorption/ionization on silicon-mass spectrometry

Suni, N. M., Haapala, M., Färm, E., Härkönen, E., Ritala, M., Sainiemi, L., Franssila, S., Kotiaho, T. & Kostiainen, R., 2010, In : Lab on a Chip. 10, 13, p. 1689-1695 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Feasibility of capillary liquid chromatography/microchip atmospheric pressure photoionization mass spectrometry in analyzing anabolic steroids in urine samples

Ahonen, L. L., Haapala, M., Saarela, V., Franssila, S., Kotiaho, T. & Kostiainen, R., 2010, In : Rapid Communications in Mass Spectrometry. 24, 7, p. 958-964 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Feasibility of gas chromatography-microchip atmospheric pressure photoionization-mass spectrometry in analysis of anabolic steroids

Hintikka, L., Haapala, M., Franssila, S., Kuuranne, T., Leinonen, A. & Kostiainen, R., 2010, In : Journal of Chromatography. A. 1217, 52, p. 8290-8297 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Feasibility of SU-8-Based Capillary Electrophoresis-Electrospray Ionization Mass Spectrometry Microfluidic Chips in the Analysis of Human Cell Lysates

Nordman, N., Sikanen, T., Aura, S., Tuomikoski, S., Vuorensola, K., Kotiaho, T., Franssila, S. & Kostiainen, R., 2010, In : Electrophoresis. 31, 22, p. 3745-3753

Research output: Contribution to journalArticleScientificpeer-review

Glucuronidation of racemic O-desmethyltramadol, the active metabolite of tramadol

Lehtonen, P., Sten, T., Aitio, O. M. A., Kurkela, M., Vuorensola, K., Finel, M. & Kostiainen, R., 2010, In : European Journal of Pharmaceutical Sciences. 41, 3/4, p. 523-530 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Hybrid Ceramic Polymers: New, Nonbiofouling, and Optically Transparent Materials for Microfluidics

Sikanen, T., Aura, S., Heikkilä, L., Kotiaho, T., Franssila, S. & Kostiainen, R., 2010, In : Analytical Chemistry. 82, 9, p. 3874-3882 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Implementation of droplet-membrane-droplet liquid-phase microextraction under stagnant conditions for lab-on-a-chip applications

Sikanen, T., Pedersen-Bjergaard, S., Jensen, H., Kostiainen, R., Rasmussen, K. E. & Kotiaho, T., 2010, In : Analytica Chimica Acta. 658, 2, p. 133-140 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Integrated liquid chromatography-heated nebulizer microchip for mass spectrometry

Haapala, M., Saarela, V., Pol, J., Kolari, K., Kotiaho, T., Franssila, S. & Kostiainen, R., 2010, In : Analytica Chimica Acta. 662, 2, p. 163-169 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Ionspray microchip

Pol, J., Kauppila, T. J., Franssila, S., Kotiaho, T. & Kostiainen, R., Sep 2010, In : Rapid Communications in Mass Spectrometry. 24, 17, p. 2584-2590 7 p.

Research output: Contribution to journalArticleScientificpeer-review

2009

Analysis of intact glucuronides and sulfates of serotonin, dopamine, and their phase I metabolites in rat brain microdialysates by liquid chromatography - tandem mass spectrometry

Uutela, P., Reinilä, R., Harju, K., Piepponen, P., Ketola, R. A. & Kostiainen, R., 2009, In : Analytical Chemistry. 81, 20, p. 8417-8425 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Atmospheric pressure thermospray ionization using a heated microchip nebulizer

Keski-Rahkonen, P., Haapala, M., Saarela, V., Franssila, S., Kotiaho, T., Kostiainen, R. & Auriola, S., 2009, In : Rapid Communications in Mass Spectrometry. 23, 20, p. 3313-3322 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Automated ambient desorption - ionization platform for surface imaging integrated with a commercial fourier transform ion cyclotron resonance mass spectrometer

Pol, J., Vidova, V., Kruppa, G., Kobliha, V., Novak, P., Lemr, K., Kotiaho, T., Kostiainen, R., Havlicek, V. & Volny, M., 2009, In : Analytical Chemistry. 81, 20, p. 8479-8487 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Characterization of metabolites of sibutramine in primary cultures of rat hepatocytes by liquid chromatography-ion trap mass spectrometry

Hakala, K., Link, M., Szotakova, B., Skalova, L., Kostiainen, R. & Ketola, R. A., 2009, In : Analytical and Bioanalytical Chemistry. p. 1327-1336 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Comparison of different amino acid derivatives and analysis of rat brain microdialysates by liquid chromatography tandem mass spectrometry

Uutela, P., Ketola, R. A., Piepponen, P. & Kostiainen, R., 2009, In : Analytica Chimica Acta. 633, 2, p. 223-231 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Discovery of dopamine glucuronide in rat and mouse brain microdialysis samples using liquid chromatography tandem mass spectrometry

Uutela, P. S., Karhu, L., Piepponen, T. P., Käenmäki, M., Ketola, R. & Kostiainen, R., 2009, In : Analytical Chemistry. 2009, 81, p. 427-434

Research output: Contribution to journalArticleScientificpeer-review

Discovery of neurosteroid glucuronides in mouse brain

Kallonen, S., Tammimäki, A., Piepponen, P., Raattamaa, H., Ketola, R. A. & Kostiainen, R., 2009, In : Analytica Chimica Acta. 651, 1, p. 69-74 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Dopamine Is a Low-Affinity and High-Specificity Substrate for the Human UDP-Glucuronosyltransferase 1A10

Itäaho, K., Court, M. H., Uutela, P., Kostiainen, R., Radominska-Pandya, A. & Finel, M., Apr 2009, In : Drug Metabolism and Disposition. 37, 4, p. 768-775 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Drosophila FoxO regulates organism size and stress resistance through an adenylate cyclase

Mattila, J. I., Bremer, A., Ahonen, L., Kostiainen, R. & Puig, O., 2009, In : Molecular and Cellular Biology. 29, 19, p. 5357-5365 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Electrospray encapsulation of hydrophilic and hydrophobic drugs in poly(L-lactic acid) nanoparticles

Valo, H. K., Peltonen, L., Vehviläinen, S., Karjalainen, M., Kostiainen, R., Laaksonen, T. J. & Hirvonen, J., 2009, In : Small. 5, 15, p. 1791-1798 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Microchip atmospheric pressure photoionization for analysis of petroleum by fourier transform ion cyclotron resonance mass spectrometry

Haapala, M., Purcell, J., Saarela, V., Franssila, S., Rodgers, R., Hendrickson, C., Kotiaho, T., Marshall, A. G. & Kostiainen, R., 2009, In : Analytical Chemistry. 81, 7, p. 2799-2803 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Microfluidic heated gas jet shape analysis by temperature scanning

Saarela, V., Haapala, M., Kostiainen, R., Kotiaho, T. & Franssila, S., 2009, In : Journal of Micromechanics and Microengineering. 19, 5, 10 s

Research output: Contribution to journalArticleScientificpeer-review

Synthesis, structure characterization, and enzyme screening of clenbuterol glucuronides

Alonen, A., Gartman, M., Aitio, O., Finel, M., Yli-Kauhaluoma, J. & Kostiainen, R., 2009, In : European Journal of Pharmaceutical Sciences. 37, 5, p. 581-587 7 p.

Research output: Contribution to journalArticleScientificpeer-review

2008

Analytical characterization of microfabricated SU-8 emitters for electrospray ionization mass spectrometry

Sikanen, T., Tuomikoski, S., Ketola, R. A., Kostiainen, R., Franssila, S. & Kotiaho, T., 2008, In : Journal of Mass Spectrometry. 43, 6, p. 726-735 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Application of silicon nanowires and indium tin oxide surfaces in desorption electrospray ionization

Pol, J., Novak, P., Thevis, M., Volny, M., Kruppa, G., Kostiainen, R., Lemr, K. & Havlicek, V., 2008, In : European Journal of Mass Spectrometry. 14, p. 391-399 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Aryl-propionamide-derived selective androgen receptor modulators: liquid chromatography-tandem mass spectrometry characterization of the in vitro synthesized metabolites for doping control purposes

Kuuranne, T., Leinonen, A., Schänzer, W., Kamber, M., Kostiainen, R. & Thevis, M., 2008, In : Drug Metabolism and Disposition. 36, 3, p. 571-581 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Carbohydrate and steroid analysis by desorption electrospray ionization mass spectrometry

Kauppila, T., Talaty, N., Jackson, A., Kotiaho, T., Kostiainen, R. & Cooks, R. G., 2008, In : Chemical Communications. 2008, 23, p. 2674 - 2676 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Characterization of the in vitro metabolic profile of amlodipine in rat using liquid chromatography-mass spectrometry

Suchanova, B., Kostiainen, R. & Ketola, R. A., 2008, In : European Journal of Pharmaceutical Sciences. 33, 1, p. 91-99

Research output: Contribution to journalArticleScientificpeer-review

Desorption and ionization mechanisms in desorption atmospheric pressure photoionization

Luosujärvi, L., Arvola, V., Haapala, M., Jaroslav, P., Saarela, V., Franssila, S., Kotiaho, T., Kostiainen, R. & Kauppila, T., 2008, In : Analytical Chemistry. 80, 19, p. 7460 - 7466 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Direct analysis of illicit drugs by desorption atmospheric pressure photolonization

Kauppila, T. J., Arvola, V., Haapala, M., Pol, J., Aalberg, L., Saarela, V., Franssila, S., Kotiaho, T. & Kostiainen, R., Apr 2008, In : Rapid Communications in Mass Spectrometry. 22, 7, p. 979-985 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Enzyme-assisted synthesis and structure characterization of glucuronic acid conjugates of losartan, candesartan, and zolarsartan

Alonen, A., Jansson, J., Kallonen, S., Kiriazis, A., Aitio, O., Finel, M. & Kostiainen, R., 2008, In : Bioorganic Chemistry. 36, 3, p. 148-155 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Enzyme-assisted synthesis and structure characterization of glucuronide conjugates of eleven anabolic steroid metabolites

Hintikka, L., Kuuranne, T., Aitio, O., Thevis, M., Schaenzer, W. & Kostiainen, R., 2008, In : Steroids. 73, 3, p. 257-265 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Fabrication and fluidic characterization of silicon micropillar array electrospray ionization chip

Sainiemi, L., Nissilä, T., Jokinen, V., Sikanen, T., Kotiaho, T., Kostiainen, R., Ketola, R. A. & Franssila, S., 2008, In : Sensors and Actuators B: Chemical. 132, 2, p. 380-387 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Gas chromatography/mass spectrometry of polychlorinated biphenyls using atmospheric pressure chemical ionization and atmospheric pressure photoionization microchips

Luosujärvi, L., Karikko, M-M., Haapala, M., Saarela, V., Huhtala, S., Franssila, S., Kostiainen, R., Kotiaho, T. & Kauppila, T., 2008, In : Rapid Communications in Mass Spectrometry. 22, 4, p. 425-431 7 p.

Research output: Contribution to journalArticleScientificpeer-review

LC-MS-MS identification of albendazole and flubendazole metabolites formed ex vivo by Haemonchus contortus

Cvilink, V., Skalova, L., Szotakova, B., Lamka, J., Kostiainen, R. & Ketola, R. A., 2008, In : Analytical and Bioanalytical Chemistry. 391, 1, p. 337-343 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Liquid chromatographic-mass spectrometric analysis of glucuronide-conjugated anabolic steroid metabolites: method validation and interlaboratory comparison

Hintikka, L., Kuuranne, T., Leinonen, A., Thevis, M., Schänzer, W., Halket, J., Cowan, D., Grosse, J., Hemmersbach, P., Nielen, M. & Kostiainen, R., 2008, In : Journal of Mass Spectrometry. 43, 7, p. 965-973 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Screening of in vitro synthesised metabolites of 4,9,11-trien-3-one steroids by liquid chromatography-mass spectrometry

Kuuranne, T., Pystynen, K-H., Thevis, M., Leinonen, A., Schänzer, A. & Kostiainen, R., 2008, In : European Journal of Mass Spectrometry. 14, p. 181-189 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Selective surface patterning with an electric discharge in the fabrication of microfluidic structures

Suni, N. M., Haapala, M., Mäkinen, A., Sainiemi, L., Franssila, S., Färm, E., Puukilainen, E., Ritala, M. & Kostiainen, R., 2008, In : Angewandte Chemie (International Edition). 47, 39, p. 7442-7445 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Simple coupling of gas chromatography to electrospray ionization mass spectrometry

Brenner, N., Haapala, M., Vuorensola, K. & Kostiainen, R., 2008, In : Analytical Chemistry. 80, 21, p. 8334 - 8339 6 p.

Research output: Contribution to journalArticleScientificpeer-review

The human UDP-glucuronosyltransferase UGT1A3 is highly selective towards N2 in the tetrazole ring of losartan, candesartan, and zolarsartan

Alonen, A., Finel, M. & Kostiainen, R., 2008, In : Biochemical Pharmacology. 76, 6, p. 763-772 10 p.

Research output: Contribution to journalArticleScientificpeer-review

2007

Desorption atmospheric pressure photoionization

Haapala, M., Pol, J., Saarela, V., Arvola, V., Kotiaho, T., Ketola, R. A., Franssila, S., Kauppila, T. & Kostiainen, R., 2007, In : Analytical Chemistry. 79, 20, p. 7867-7872

Research output: Contribution to journalArticleScientificpeer-review