Risto Lapatto

Publications

Research output per year 1998 2003 2016 2019 2020 2021 2022 2023

• 38 Article
• 9 Chapter
• 3 Review Article
• 2 Editorial
• 1 More
  • 1 Conference article

Research output per year

Research output per year

Search results

• 2023

  European expert recommendations on clinical investigation and evaluation of high-risk medical devices for children

  the European Academy of Paediatrics, Guerlich, K., Patro-Golab, B., Barnacle, A., Baumann, U., Eicken, A. G., Fraser, A., Gruszfeld, D. A., Haas, N. H., Jonker, A., Kammermeier, M., Kenny, D., Kolacek, S., Lapatto, R., Maconochie, I., Mader, S., McGauran, G., Melvin, T., Muensterer, O., Piscoi, P., & 6 othersRomano, A. K., Saxena, A. T., Schneider, D. A., Turner, M., Vande Walle, J. & Koletzko, B., Aug 2023, (E-pub ahead of print) In: Acta Paediatrica. 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access
• 2022

  Availability and use of rapid diagnostic tests for the management of acute childhood infections in Europe: A cross-sectional survey of paediatricians

  Dewez, J. E., Pembrey, L., Nijman, R. G., del Torso, S., Grossman, Z., Hadjipanayis, A., Van Esso, D., Lim, E., Emonts, M., Burns, J., Gras-LeGuen, C., Kohlfuerst, D., Dornbusch, H. J., Brengel-Pesce, K., Mallet, F., von Both, U., Tsolia, M., Eleftheriou, I., Zavadska, D., de Groot, R., & 34 othersvan der Flier, M., Moll, H., Hagedoorn, N., Borensztajn, D., Oostenbrink, R., Kuijpers, T., Pokorn, M., Vincek, K., Martinon-Torres, F., Rivero, I., Agyeman, P., Carrol, E. D., Paulus, S., Cunnington, A., Herberg, J., Levin, M., Mujkic, A., Geitmann, K., Da Dalt, L., Syridou, G., Valiulis, A., Lapatto, R., Altorjai, P., Torpiano, P., Størdal, K., Illy, K., Mazur, A., Spreitzer, M. V., Rios, J., Wyder, C., Romankevych, I., Basmaci, R., Ibanez-Mico, S. & Yeung, S., 20 Dec 2022, In: PLoS One. 17, 12, 22 p., e0275336.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• CRISPR correction of the Finnish ornithine delta-aminotransferase mutation restores metabolic homeostasis in iPSC from patients with gyrate atrophy

  Maldonado, R., Jalil, S., Keskinen, T., Nieminen, A. I., Hyvönen, M. E., Lapatto, R. & Wartiovaara, K., Jun 2022, In: Molecular Genetics and Metabolism Reports. 31, 6 p., 100863.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Expert guidance on the multidisciplinary management of cystinosis in adolescent and adult patients

  Levtchenko, E., Servais, A., Hulton, S. A., Ariceta, G., Emma, F., Game, D. S., Lange, K., Lapatto, R., Liang, H., Sberro-Soussan, R., Topaloglu, R., Das, A. M., Webb, N. J. A. & Wanner, C., 22 Aug 2022, In: Clinical kidney journal. 15, 9, p. 1675-1684 10 p.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

  File

• The Finnish genetic heritage in 2022 - from diagnosis to translational research

  Uusimaa, J., Kettunen, J., Varilo, T., Järvelä, I., Kallijärvi, J., Kääriäinen, H., Laine, M., Lapatto, R., Myllynen, P., Niinikoski, H., Rahikkala, E., Suomalainen, A., Tikkanen, R., Tyynismaa, H., Vieira, P., Zarybnicky, T., Sipilä, P., Kuure, S. & Hinttala, R., 1 Oct 2022, In: Disease Models & Mechanisms. 15, 10, 18 p., dmm049490.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

  File
• 2021

  An eHealth Framework for Managing Pediatric Growth Disorders and Growth Hormone Therapy

  Dimitri, P., Fernandez-Luque, L., Banerjee, I., Bergada, I., Calliari, L. E., Dahlgren, J., de Arriba, A., Lapatto, R., Reinehr, T., Senniappan, S., Thomas-Teinturier, C., Tsai, M-C., Zaini, A. A., Bagha, M. & Koledova, E., 20 May 2021, In: Journal of Medical Internet Research. 23, 5, 13 p., 27446.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Connected health for growth hormone treatment research and clinical practice: learnings from different sources of real-world evidence (RWE)-large electronically collected datasets, surveillance studies and individual patients' cases

  Boman, N., Fernandez-Luque, L., Koledova, E., Kause, M. & Lapatto, R., 26 Apr 2021, In: BMC Medical Informatics and Decision Making. 21, 1, 12 p., 136.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Eurooppalainen erikoislääkärikuulustelu parantaa osaamisen arviointia

  Merenmies, J. & Lapatto, R., 2021, In: Duodecim. 137, 20, p. 2093-2095 3 p.

  Research output: Contribution to journal › Editorial › Professional

  Open Access

  File

• Motivational Interviewing and Glycemic Control in Adolescents With Poorly Controlled Type 1 Diabetes: A Randomized Controlled Pilot Trial

  Tuomaala, A-K., Hero, M., Tuomisto, M. T., Lähteenmäki, M., Miettinen, P. J., Laine, T., Wehkalampi, K., Kiiveri, S., Ahonen, P., Ojaniemi, M., Kaunisto, K., Tossavainen, P., Lapatto, R., Sarkola, T. & Pulkkinen, M-A., 12 Mar 2021, In: Frontiers in Endocrinology. 12, 9 p., 639507.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2020

  Adrenal function after induction therapy for acute lymphoblastic leukemia in children short: adrenal function in ALL

  Loimijoki, T., Lapatto, R. & Taskinen, M., Sep 2020, In: European journal of pediatrics. 179, 9, p. 1453-1459 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Ei-alkoholiperäinen rasvamaksatauti (NAFLD)

  Yki-Järvinen, H., Arkkila, P., Eskelinen, S., Juuti, A., Lapatto, R., Lempiäinen, A., Mervaala, E., Schwab Nikkola, A. & Winterfeld, U., 2020, In: Duodecim. 136, 4, p. 403-405 3 p.

  Research output: Contribution to journal › Article › Professional

  Open Access

  File

• Intratekaalinen lääkitys - oikotie aivoihin keskushermostosairauksien hoidossa

  Isohanni, P., Lapatto, R. & Lönnqvist, T., 2020, In: Duodecim. 136, 18, p. 1989-1991 3 p.

  Research output: Contribution to journal › Editorial › Professional

  Open Access

  File

• Pikkupoika lakkasi kävelemästä

  Lapatto, R., 2020, In: Suomen lääkärilehti. 75, 21, p. 1312, 1316 2 p.

  Research output: Contribution to journal › Article › Professional

  Open Access

  File
• 2019

  Aineenvaihduntasairauksien ruokavaliohoito ja suunterveys

  Rönty, L., Alapulli, H., Tuokkola, J. & Lapatto, R., 2019, In: Suomen hammaslääkärilehti. 26, 3, p. 22-26 5 p.

  Research output: Contribution to journal › Article › Professional

• Aineenvaihduntatautien seulonta

  Niinikoski, H. & Lapatto, R., 2019, Vastasyntyneiden akuuttihoito. Luukkainen, P., Metsäranta, M. & Sankilampi, U. (eds.). 1. p. ed. Helsinki: Duodecim, p. 348-350 3 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Akuutin hyperammonemian selvittely ja hoito

  Lapatto, R. & Rantakari, K., 2019, Vastasyntyneiden akuuttihoito. Luukkainen, P., Metsäranta, M. & Sankilampi, U. (eds.). 1. p. ed. Helsinki: Duodecim, p. 279-281 3 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Clinical, biochemical, and molecular overview of transaldolase deficiency and evaluation of the endocrine function: Update of 34 patients

  Williams, M., Valayannopoulos, V., Altassan, R., Chung, W. K., Heijboer, A. C., Keng, W. T., Lapatto, R., McClean, P., Mulder, M. F., Tylki-Szymanska, A., Walenkamp, M-J. E., Alfadhel, M., Alakeel, H., Salomons, G. S., Eyaid, W. & Wamelink, M. M. C., Jan 2019, In: Journal of Inherited Metabolic Disease. 42, 1, p. 147-158 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Metabolisen kriisin hoito

  Lapatto, R. & Rantakari, K., 2019, Vastasyntyneiden akuuttihoito. Luukkainen, P., Metsäranta, M. & Sankilampi, U. (eds.). 1. p. ed. Helsinki: Duodecim, p. 277-279 3 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Metabolisten tautien diagnostiikka

  Lapatto, R. & Rantakari, K., 2019, Vastasyntyneiden akuuttihoito. Luukkainen, P., Metsäranta, M. & Sankilampi, U. (eds.). 1. p. ed. Helsinki: Duodecim, p. 273-277 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Neonatal screening av metabola sjukdomar

  Lapatto, R., 2019, In: Finska Läkaresällskapets Handlingar. 179, 1, p. 40-45 6 p.

  Research output: Contribution to journal › Article › Professional

  Open Access

  File

• Vastasyntyneen maksasairaudet

  Lapatto, R. & Saarinen, K., 2019, Vastasyntyneiden akuuttihoito. Luukkainen, P., Metsäranta, M. & Sankilampi, U. (eds.). 1. p. ed. Helsinki: Duodecim, p. 236-240 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• 2018

  Lysinuurinen proteiini-intoleranssi ja muut perinnölliset hyperammonemiat

  Lapatto, R., 2018, In: Erikoislääkäri. 28, 4, p. 156-159 4 p.

  Research output: Contribution to journal › Article › Professional

• Vastasyntyneiden aineenvaihduntasairauksien seulonta

  Lapatto, R., Niinikoski, H. & Mononen, I., 2018, In: Duodecim. 134, 3, p. 263-269 7 p.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

  File
• 2017

  Stress-Dose Corticosteroid Versus Placebo in Neonatal Cardiac Operations: A Randomized Controlled Trial

  Suominen, P. K., Keski-Nisula, J., Ojala, T., Rautiainen, P., Jahnukainen, T., Hastbacka, J., Neuvonen, P. J., Pitkanen, O., Niemela, J., Kaskinen, A., Salminen, J. & Lapatto, R., Oct 2017, In: Annals of Thoracic Surgery. 104, 4, p. 1378-1385 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2016

  Earlier diagnosis and strict diets improve the survival rate and clinical course of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency

  Immonen, T., Turanlahti, M., Paganus, A., Keskinen, P., Tyni, T. & Lapatto, R., 2016, In: Acta Paediatrica. 105, 5, p. 549-554 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Incidence and outcome of epilepsy syndromes with onset in the first year of life: A retrospective population-based study

  Gaily, E., Lommi, M., Lapatto, R. & Lehesjoki, A-E., Oct 2016, In: Epilepsia. 57, 10, p. 1594-1601 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Metabolisen taudin epäily

  Lapatto, R. & Niinikoski, H., 2016, Lastentautien päivystyskirja. Korppi, M., Kröger, L., Rantala, H. & Niinikoski, H. (eds.). 3. uud. p. ed. Helsinki: Duodecim, p. 213-215 3 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Metabolisen taudin hoito

  Lapatto, R. & Niinikoski, H., 2016, Lastentautien päivystyskirja. Korppi, M., Kröger, L., Rantala, H. & Niinikoski, H. (eds.). 3. uud. p. ed. Helsinki: Duodecim, p. 216-218 3 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Peripheral neuropathy in patients with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency - A follow-up EMG study of 12 patients

  Immonen, T., Ahola, E., Toppila, J., Lapatto, R., Tyni, T. & Lauronen, L., Jan 2016, In: European Journal of Paediatric Neurology. 20, 1, p. 38-44 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Seulomalla vauvat ajoissa hoitoon

  Lapatto, R., 2016, In: Sic! Lääketietoa Fimeasta. 6, 4, p. 37-38 2 p.

  Research output: Contribution to journal › Article › Professional

  Open Access

  File
• 2015

  LMNA Mutation c.917T > G (p.L306R) Leads to Deleterious Hyper-Assembly of Lamin A/C and Associates with Severe Right Ventricular Cardiomyopathy and Premature Aging

  Alastalo, T-P., West, G., Li, S-P., Keinanen, A., Helenius, M., Tyni, T., Lapatto, R., Turanlahti, M., Heikkila, P., Kääriäinen, H., Laakso, M., Mauermann, M., Herrmann, H., Pihkala, J. & Taimen, P., Jul 2015, In: Human Mutation. 36, 7, p. 694-703 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Vastasyntyneen aineenvaihduntasairauksien seulonta

  Lapatto, R., 2015, In: Moodi. 39, 2, p. 62-63 2 p.

  Research output: Contribution to journal › Article › Professional

• 2013

  Metabolinen kriisi

  Lapatto, R. & Fellman, V., 2013, Vastasyntyneiden tehohoito. Fellman, V., Luukkainen, P. & Asikainen, T. (eds.). 3. uud. p. ed. Helsinki: Duodecim, p. 259-267 9 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Suomen vastasyntyneille kuuluu oikeus aineenvaihduntasairauksien seulontaan

  Lapatto, R., 2013, In: Suomen lääkärilehti. 68, 17, p. 1235 1 p.

  Research output: Contribution to journal › Article › Professional

• Vastasyntyneen maksasairaudet

  Lapatto, R. & Fellman, V., 2013, Vastasyntyneiden tehohoito. Fellman, V., Luukkainen, P. & Asikainen, T. (eds.). 3. uud. p. ed. Helsinki: Duodecim, p. 223-225 3 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• 2012

  Patients with organic acidaemias have an altered thiol status

  Salmi, H., Leonard, J. V. & Lapatto, R., 1 Nov 2012, In: Acta Paediatrica. 101, 11, p. e505-e508 4 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Plasma thiol status is altered in children with mitochondrial diseases

  Salmi, H., Leonard, J. V., Rahman, S. & Lapatto, R., 2012, In: Scandinavian Journal of Clinical & Laboratory Investigation. 72, 2, p. 152-157 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2011

  Change in plasma and erythrocyte thiol levels in children undergoing fasting studies for investigation of hypoglycaemia

  Salmi, H., Hussain, K. & Lapatto, R. J., 2011, In: Pediatric Endocrinology, Diabetes and, Metabolism. 17, 1, p. 14-19 6 p.

  Research output: Contribution to journal › Article › Scientific

• GnRH-Deficient Phenotypes in Humans and Mice with Heterozygous Variants in KISS1/Kiss1

  Chan, Y-M., Broder-Fingert, S., Paraschos, S., Lapatto, R., Au, M., Hughes, V., Bianco, S. D. C., Min, L., Plummer, L., Cerrato, F., De Guillebon, A., Wu, I-H., Wahab, F., Dwyer, A., Kirsch, S., Quinton, R., Cheetham, T., Ozata, M., Ten, S., Chanoine, J-P., & 8 othersPitteloud, N., Martin, K. A., Schiffmann, R., Van der Kamp, H. J., Nader, S., Hall, J. E., Kaiser, U. B. & Seminara, S. B., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 11, p. E1771-E1781 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2010

  Cow's milk allergy is associated with changes in urinary organic acid concentrations

  Salmi, H., Kuitunen, M., Viljanen, M. & Lapatto, R., Mar 2010, In: Pediatric Allergy and Immunology. 21, 2, p. E401-E406 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Metabolomics in Angiotensin II-Induced Cardiac Hypertrophy

  Mervaala, E., Biala, A., Merasto, S., Lempiainen, J., Mattila, I., Martonen, E. E., Eriksson, O., Louhelainen, M., Finckenberg, P., Kaheinen, P., Muller, D. N., Luft, F. C., Lapatto, R. & Oresic, M., 2010, In: Hypertension. 55, 2, p. 508-515 8 p.

  Research output: Contribution to journal › Conference article › Scientific › peer-review
• 2009

  European Multicentre Study in Children Born Small for Gestational Age with Persistent Short Stature: Comparison of Continuous and Discontinuous Growth Hormone Treatment Regimens

  Phillip, M., Lebenthal, Y., Lebl, J., Zuckerman-Levin, N., Korpal-Szczyrska, M., Marques, J. S., Steensberg, A., Jons, K., Kappelgaard, A-M., Ibanez, L., European Norditropin SGA Study Grp, Lipsanen-Nyman, M., Dunkel, L., Sipilä, I., Otonkoski, T. & Lapatto, R., 2009, In: Hormone Research. 71, 1, p. 52-59 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2005

  Expanding screening for rare metabolic disease in the newborn: An analysis of costs, effect and ethical consequences for decision-making in Finland

  Autti-Rämö, I., Mäkelä, M., Sintonen, H., Koskinen, H., Laajalahti, L., Halila, R., Kääriäinen, H., Lapatto, R., Näntö-Salonen, K., Pulkki, K., Renlund, M., Salo, M. & Tyni, T., 2005, In: Acta Paediatrica. 94, 8, p. 1126-1136 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Kidneys with heavy proteinuria show fibrosis, inflammation, and oxidative stress, but no tubular phenotypic change

  Kuusniemi, A-M., Lapatto, R., Holmberg, C., Karikoski, R., Rapola, J. & Jalanko, H., 2005, In: Kidney International. 68, p. 121-132 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• 2004

  Glutathione depletion and cardiomyocyte apoptosis in viral myocarditis

  Kyto, V., Lapatto, R., Lakkisto, P., Saraste, A., Voipio-Pulkki, L. M., Vuorinen, T. & Pulkki, K., 2004, In: European Journal of Clinical Investigation. 34, p. 167-175 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Plasma 8-isoprostane is increased in preterm infants who develop bronchopulmonary dysplasia or periventricular leukomalacia

  Ahola, T., Fellman, V., Kjellmer, I., Raivio, KO. & Lapatto, R., Jul 2004, In: Pediatric Research. 56, 1, p. 88-93 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Thiol metabolism in preterm infants during the first week of life

  Ahola, T., Levonen, AL., Fellman, V. & Lapatto, R., Oct 2004, In: Scandinavian Journal of Clinical & Laboratory Investigation. 64, 7, p. 649-658 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2003

  Entacapone protects from angiotensin II-induced inflammation and renal injury

  Helkamaa, T., Finckenberg, P., Louhelainen, M., Merasto, S., Rauhala, P., Lapatto, R., Cheng, Z. J., Reenila, I., Mannisto, P., Muller, D. N., Luft, F. C. & Mervaala, E. M. A., 2003, In: Journal of Hypertension. 21, p. 2353-2363 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• N-acetylcysteine does not prevent bronchopulmonary dysplasia in immature infants: A randomized controlled trial

  Ahola, T., Lapatto, R., Raivio, KO., Selander, B., Stigson, L., Jonsson, B., Jonsbo, F., Esberg, G., Stovring, S., Kjartansson, S., Stiris, T., Lossius, K., Virkola, K. & Fellman, V., Dec 2003, In: The Journal of Pediatrics. 143, 6, p. 713-719 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Physical exercise-induced hyperinsulinemic hypoglycemia is an autosomal-dominant trait characterized by abnormal pyruvate-induced insulin release

  Otonkoski, T., Kaminen, N., Ustinov, J., Lapatto, R., Meissner, T., Mayatepek, E., Kere, J. & Sipila, I., 2003, In: Diabetes. 2003, 52, p. 199-204 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review