Robert Luxenhofer

Publications

Research output per year 2019 2020 2021 2022 2023 2025

• 43 Article
• 1 Review Article

Research output per year

Research output per year

Search results

• 2025

  Amorphous solid dispersions of amphiphilic polymer excipients and indomethacin prepared by hot melt extrusion

  Kessler, L. M., Mishra, R., Hietala, S., Lammens, M., Peltonen, L., Rades, T., van Veen, B., Juppo, A., Laaksonen, T., Strachan, C. & Luxenhofer, R., 1 Jan 2025, In: European Journal of Pharmaceutical Sciences. 204, 11 p., 106960.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2024

  A Versatile and High-Resolution Hydrogel Platform for Volumetric Additive Manufacturing Based on Poly(ethylene glycol) Diacrylate and Alginate Blends

  Hall, P. C., Chasko, D., Wheeler, T., Ostojich, D., Aptecker, J., Liashenko, I., Luxenhofer, R., Lindberg, G. C. J. & Dalton, P. D., 24 Dec 2024, In: Advanced Materials Technologies. 9 p., 2401668.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Melt electrowriting of amorphous solid dispersions: influence of drug and plasticizer on rheology and printing performance

  Kessler, L. M. & Luxenhofer, R., 15 Oct 2024, (Submitted) In: International Journal of Pharmaceutics.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Perfusable Tissue Bioprinted into a 3D-Printed Tailored Bioreactor System

  Gensler, M., Malkmus, C., Ockermann, P., Moellmann, M., Hahn, L., Salehi, S., Luxenhofer, R., Boccaccini, A. R. & Hansmann, J., Jan 2024, In: Bioengineering (Basel). 11, 1, 16 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• POxload: Machine Learning Estimates Drug Loadings of Polymeric Micelles: Molecular Pharmaceutics

  Kehrein, J., Bunker, A. & Luxenhofer, R., 2024, In: Molecular Pharmaceutics.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Self-Nanoformulating Poly(2-oxazoline) and Poly(2-oxazine) Copolymers Based Amorphous Solid Dispersions as Microneedle Patch: A Formulation Study

  D'Amico, C., Ziegler, A.-L., Kemell, M., Molinaro, G., Luxenhofer, R. & Santos, H. A., Dec 2024, In: Advanced Materials Technologies. 9, 23, 10 p., 2400766.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Thionation of Poly(2-ethyl-2-oxazoline) and Its Effect on Solubility and Cloud Point

  Hacıoglu, A., Baddam, V., Kerr, A. I., Kehrein, J., Bunker, A. E. & Luxenhofer, R., 2024, In: Macromolecules. 57, 21, p. 10368–10378 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• 2023

  Biological Activity In Vitro, Absorption, BBB Penetration, and Tolerability of Nanoformulation of BT44: RET Agonist with Disease-Modifying Potential for the Treatment of Neurodegeneration

  Haider, M. S., Mahato, A. K., Kotliarova, A., Forster, S., Böttcher, B., Stahlhut, P., Sidorova, Y. & Luxenhofer, R., 9 Oct 2023, In: Biomacromolecules. 24, 10, p. 4348–4365 18 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Biomimetic Connection of Transcutaneous Implants with Skin

  Weigel, T., Christ, B., Dembski, S., Ewald, A., Groneberg, D., Hansmann, J., Luxenhofer, R., Metzger, M., Walles, H., Willy, C., Groeber-Becker, F. & Probst, J., 3 Sept 2023, In: Advanced Healthcare Materials. 15 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Highly Porous and Drug-Loaded Amorphous Solid Dispersion Microfiber Scaffolds of Indomethacin Prepared by Melt Electrowriting

  Kessler, L., Mirzaei, Z., Kade, J. C. & Luxenhofer, R., 13 Jan 2023, In: ACS applied polymer materials. 5, 1, p. 913-922 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Investigation of cationic ring-opening polymerization of 2-oxazolines in the "green" solvent dihydrolevoglucosenone

  Borova, S. & Luxenhofer, R., 28 Feb 2023, In: Beilstein Journal of Organic Chemistry. 19, p. 217-230 14 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Structural Investigation on How Guest Loading of Poly(2-oxazoline)-Based Micelles Affects the Interaction with Simulated Intestinal Fluids

  Endres, S., Ehrmanntraut, S., Endres, L., Can, K., Kraft, C., Rasmussen, T., Luxenhofer, R., Boettcher, B., Engels, B. & Poeppler, A.-C., Aug 2023, In: Acs Biomaterials Science & Engineering. 9, 8, p. 4821-4830 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Unraveling an Alternative Mechanism in Polymer Self-Assemblies: An Order-Order Transition with Unusual Molecular Interactions between Hydrophilic and Hydrophobic Polymer Blocks

  Hahn, L., Zorn, T., Kehrein, J., Kielholz, T., Ziegler, A.-L., Forster, S., Sochor, B., Lisitsyna, E. S., Durandin, N. A., Laaksonen, T., Aseyev, V., Sotriffer, C., Saalwächter, K., Windbergs, M., Pöppler, A.-C. & Luxenhofer, R., 11 Apr 2023, In: ACS Nano. 17, 7, p. 6932–6942 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Unravel the Tangle: Atomistic Insight into Ultrahigh Curcumin-Loaded Polymer Micelles

  Kehrein, J., Gürsöz, E., Davies, M., Luxenhofer, R. & Bunker, A., 1 Nov 2023, In: Small. 19, 44, 17 p., 2303066.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• 2022

  A thermogelling organic-inorganic hybrid hydrogel with excellent printability, shape fidelity and cytocompatibility for 3D bioprinting

  Hu, C., Ahmad, T., Haider, M. S., Hahn, L., Stahlhut, P., Groll, J. & Luxenhofer, R., 1 Apr 2022, In: Biofabrication. 14, 2, 16 p., 025005.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• A Transient Initiator for Polypeptoids Postpolymerization alpha-Functionalization via Activation of a Thioester Group

  Borova, S., Schlutt, C., Nickel, J. & Luxenhofer, R., Feb 2022, In: Macromolecular Chemistry and Physics. 223, 3, 16 p., 2100331.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Concentration and composition dependent aggregation of Pluronic- and Poly-(2-oxazolin)-Efavirenz Formulations in Biorelevant Media

  Endres, S., Karaev, E., Hanio, S., Schlauersbach, J., Kraft, C., Rasmussen, T., Luxenhofer, R., Böttcher, B., Meinel, L. & Pöppler, A.-C., 15 Jan 2022, In: Journal of Colloid and Interface Science. 606, p. 1179-1192 14 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Designing Highly Stable Poly(sarcosine)-Based Telodendrimer Micelles with High Drug Content Exemplified with Fulvestrant

  Yu, Q., England, R. M., Gunnarsson, A., Luxenhofer, R., Treacher, K. & Ashford, M. B., 25 Jan 2022, In: Macromolecules. 55, 2, p. 401-412 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Merging bioresponsive release of insulin-like growth factor I with 3D printable thermogelling hydrogels

  Beudert, M., Hahn, L., Horn, A. H. C., Hauptstein, N., Sticht, H., Meinel, L., Luxenhofer, R., Gutmann, M. & Lühmann, T., Jul 2022, In: Journal of Controlled Release. 347, p. 115-126 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Synthesis and Investigation of Chiral Poly(2,4-disubstituted-2-oxazoline)-Based Triblock Copolymers, Their Self-Assembly, and Formulation with Chiral and Achiral Drugs

  Yang, M., Haider, M. S., Forster, S., Hu, C. & Luxenhofer, R., 26 Jul 2022, In: Macromolecules. 55, 14, p. 6176-6190 15 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• The Impact of Including Carbonyl Iron Particles on the Melt Electrowriting Process

  Kade, J. C., Bakirci, E., Tandon, B., Gorgol, D., Mrlik, M., Luxenhofer, R. & Dalton, P. D., Dec 2022, In: Macromolecular Materials & Engineering. 307, 12, 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• 2021

  ABA Type Amphiphiles with Poly(2-benzhydryl-2-oxazine) Moieties: Synthesis, Characterization and Inverse Thermogelation

  Hahn, L., Kessler, L., Polzin, L., Fritze, L., Forster, S., Helten, H. & Luxenhofer, R., Sept 2021, In: Macromolecular Chemistry and Physics. 222, 17, 12 p., 2100114.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• An initiator- and catalyst-free hydrogel coating process for 3D printed medical-grade poly(epsilon-caprolactone)

  Loeblein, J., Lorson, T., Komma, M., Kielholz, T., Windbergs, M., Dalton, P. D. & Luxenhofer, R., 19 Aug 2021, In: Beilstein Journal of Organic Chemistry. 17, p. 2095-2101 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• An Inverse Thermogelling Bioink Based on an ABA-Type Poly(2-oxazoline) Amphiphile

  Hahn, L., Karakaya, E., Zorn, T., Sochor, B., Maier, M., Stahlhut, P., Forster, S., Fischer, K., Seiffert, S., Pöppler, A.-C., Detsch, R. & Luxenhofer, R., 12 Jul 2021, In: Biomacromolecules. 22, 7, p. 3017-3027 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Development of a 3D printable and highly stretchable ternary organic-inorganic nanocomposite hydrogel

  Hu, C., Haider, M. S., Hahn, L., Yang, M. & Luxenhofer, R., 14 Jun 2021, In: Journal of Materials Chemistry. B. 9, 22, p. 4535-4545 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Development of polymer-based nanoparticles for Zileuton delivery to the lung: PMeOx and PMeOzi surface chemistry reduces interactions with mucins

  Drago, S. E., Craparo, E. F., Luxenhofer, R. & Cavallaro, G., Oct 2021, In: Nanomedicine: Nanotechnology, Biology and Medicine. 37, 15 p., 102451.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Freeform direct laser writing of versatile topological 3D scaffolds enabled by intrinsic support hydrogel

  Hasselmann, S., Hahn, L., Lorson, T., Schaetzlein, E., Sebastien, I., Beudert, M., Luehmann, T., Neubauer, J. C., Sextl, G., Luxenhofer, R. & Heinrich, D., 29 Nov 2021, In: Materials Horizons. 8, 12, p. 3334-3344 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• From Thermogelling Hydrogels toward Functional Bioinks: Controlled Modification and Cytocompatible Crosslinking

  Hahn, L., Beudert, M., Gutmann, M., Kessler, L., Stahlhut, P., Fischer, L., Karakaya, E., Lorson, T., Thievessen, I., Detsch, R., Luehmann, T. & Luxenhofer, R., Oct 2021, In: Macromolecular Bioscience. 21, 10, 9 p., 2100122.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Improving printability of a thermoresponsive hydrogel biomaterial ink by nanoclay addition

  Hu, C., Hahn, L., Yang, M., Altmann, A., Stahlhut, P., Groll, J. & Luxenhofer, R., Jan 2021, In: Journal of Materials Science. 56, 1, p. 691-705 15 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Melt electrowriting of poly(vinylidene difluoride) using a heated collector

  Kade, J. C., Otto, P. F., Luxenhofer, R. & Dalton, P. D., Dec 2021, In: Polymers for Advanced Technologies. 32, 12, p. 4951-4955 5 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Melt electrowriting of poly(vinylidene fluoride-co-trifluoroethylene): Melt electrowriting of poly(vinylidene fluoride-co-trifluoroethylene)

  Kade, J. C., Tandon, B., Weichhold, J., Pisignano, D., Persano, L., Luxenhofer, R. & Dalton, P. D., 2021, In: Polymer International. 70, 12, p. 1725-1732 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Poly(2-ethyl-2-oxazoline-co-N-propylethylene imine)s by controlled partial reduction of poly(2-ethyl-2-oxazoline): synthesis, characterization and cytotoxicity

  Halupczok, S., Pfister, M., Ringhand, A., Fetsch, C., Cubukova, A., Appelt-Menzel, A. & Luxenhofer, R., 7 Feb 2021, In: Polymer Chemistry. 12, 5, p. 680-688 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Poly(2-oxazoline)- and Poly(2-oxazine)-Based Self-Assemblies, Polyplexes, and Drug Nanoformulations-An Update

  Zahoranova, A. & Luxenhofer, R., Mar 2021, In: Advanced Healthcare Materials. 10, 6, 27 p., 2001382.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

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• The Challenging Pharmacokinetics of Mitotane: An Old Drug in Need of New Packaging

  Haider, M. S., Ahmad, T., Groll, J., Scherf-Clavel, O., Kroiss, M. & Luxenhofer, R., Sept 2021, In: European Journal of Drug Metabolism and Pharmacokinetics. 46, p. 575-593 19 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Tuning the Thermogelation and Rheology of Poly(2-Oxazoline)/Poly(2-Oxazine)s Based Thermosensitive Hydrogels for 3D Bioprinting

  Haider, M. S., Ahmad, T., Yang, M., Hu, C., Hahn, L., Stahlhut, P., Groll, J. & Luxenhofer, R., Sept 2021, In: Gels. 7, 3, 21 p., 78.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• 2020

  A tutorial translation of the description of the historically first polymer drug conjugate and its in vivo evaluation

  Luxenhofer, R., Sept 2020, In: Zeitschrift für Naturforschung. Section C: A Journal of Biosciences. 75, 9-10, p. 303-311 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• A versatile biomaterial ink platform for the melt electrowriting of chemically-crosslinked hydrogels

  Nahm, D., Weigl, F., Schaefer, N., Sancho, A., Frank, A., Groll, J., Villmann, C., Schmidt, H.-W., Dalton, P. D. & Luxenhofer, R., 1 Mar 2020, In: Materials Horizons. 7, 3, p. 928-933 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Crosslinking of hydrophilic polymers using polyperoxides

  Borova, S., Tokarev, V., Stahlhut, P. & Luxenhofer, R., Dec 2020, In: Colloid and Polymer Science. 298, 12, p. 1699-1713 15 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Inverse Thermogelation of Aqueous Triblock Copolymer Solutions into Macroporous Shear-Thinning 3D Printable Inks

  Hahn, L., Maier, M., Stahlhut, P., Beudert, M., Flegler, V., Forster, S., Altmann, A., Toeppke, F., Fischer, K., Seiffert, S., Boettcher, B., Luehmann, T. & Luxenhofer, R., 18 Mar 2020, In: ACS Applied Materials & Interfaces. 12, 11, p. 12445-12456 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• In Vitro Blood-Brain Barrier Permeability and Cytotoxicity of an Atorvastatin-Loaded Nanoformulation Against Glioblastoma in 2D and 3D Models

  Luebtow, M. M., Oerter, S., Quader, S., Jeanclos, E., Cubukova, A., Krafft, M., Haider, M. S., Schulte, C., Meier, L., Rist, M., Sampetrean, O., Kinoh, H., Gohla, A., Kataoka, K., Appelt-Menzel, A. & Luxenhofer, R., 1 Jun 2020, In: Molecular Pharmaceutics. 17, 6, p. 1835-1847 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Low dose novel PARP-PI3K inhibition via nanoformulation improves colorectal cancer immunoradiotherapy

  Landry, M. R., DuRoss, A. N., Neufeld, M. J., Hahn, L., Sahay, G., Luxenhofer, R. & Sun, C., Sept 2020, In: Materials today bio. 8, 13 p., 100082.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Probing the Complex Loading-Dependent Structural Changes in Ultrahigh Drug-Loaded Polymer Micelles by Small-Angle Neutron Scattering

  Sochor, B., Dudukcu, O., Luebtow, M. M., Schummer, B., Jaksch, S. & Luxenhofer, R., 7 Apr 2020, In: Langmuir. 36, 13, p. 3494-3503 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Think Beyond the Core: Impact of the Hydrophilic Corona on Drug Solubilization Using Polymer Micelles

  Haider, M. S., Luebtow, M. M., Endres, S., Forster, S., Flegler, V. J., Boettcher, B., Aseyev, V., Pöppler, A.-C. & Luxenhofer, R., 3 Jun 2020, In: ACS Applied Materials & Interfaces. 12, 22, p. 24531-24543 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• 2019

  Loading-Dependent Structural Model of Polymeric Micelles Encapsulating Curcumin by Solid-State NMR Spectroscopy

  Poeppler, A.-C., Luebtow, M. M., Schlauersbach, J., Wiest, J., Meinel, L. & Luxenhofer, R., 4 Nov 2019, In: Angewandte Chemie (International Edition). 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access