20122016
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Personal profile

Keywords

  • 3112 Neurosciences
  • Mitochondrial disease
  • 1182 Biochemistry, cell and molecular biology
  • 318 Medical biotechnology

International and National Collaboration Publications and projects within past five years.

Publications 2012 2016

FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders

Lehtonen, J. M., Forsstrom, S., Bottani, E., Viscomi, C., Baris, O. R., Isoniemi, H., Hockerstedt, K., Osterlund, P., Hurme, M., Jylhava, J., Leppa, S., Markkula, R., Helio, T., Mombelli, G., Uusimaa, J., Laaksonen, R., Laaksovirta, H., Auranen, M., Zeviani, M., Smeitink, J. & 4 othersWiesner, R. J., Nakada, K., Isohanni, P. & Suomalainen, A., 29 Nov 2016, In : Neurology. 87, 22, p. 2290-2299 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism

Nikkanen, J., Forsstrom, S., Euro, L., Paetau, I., Kohnz, R. A., Wang, L., Chilov, D., Viinamaki, J., Roivainen, A., Marjamaki, P., Liljenback, H., Ahola, S., Buzkova, J., Terzioglu, M., Khan, N. A., Pirnes-Karhu, S., Paetau, A., Lonnqvist, T., Sajantila, A., Isohanni, P. & 6 othersTyynismaa, H., Nomura, D. K., Battersby, B. J., Velagapudi, V., Carroll, C. J. & Suomalainen, A., 12 Apr 2016, In : Cell Metabolism. 23, 4, p. 635-648 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health

Laurila, P-P., Soronen, J., Kooijman, S., Forsstrom, S., Boon, M. R., Surakka, I., Kaiharju, E., Coomans, C. P., Van den Berg, S. A. A., Autio, A., Sarin, A-P., Kettunen, J., Tikkanen, E., Manninen, T., Metso, J., Silvennoinen, R., Merikanto, K., Ruuth, M., Perttila, J., Makela, A. & 27 othersIsomi, A., Tuomainen, A. M., Tikka, A., Ramadan, U. A., Seppala, I., Lehtimaki, T., Eriksson, J., Havulinna, A., Jula, A., Karhunen, P. J., Salomaa, V., Perola, M., Ehnholm, C., Lee-Rueckert, M., Van Eck, M., Roivainen, A., Taskinen, M-R., Palotie, L., Mervaala, E., Jalanko, A., Hohtola, E., Olkkonen, V. M., Ripatti, S., Kovanen, P. T., Rensen, P. C. N., Suomalainen, A. & Jauhiainenit, M., 27 Jan 2016, In : Science translational medicine. 8, 323, 19 p., ARTN 323ra13.

Research output: Contribution to journalArticleScientificpeer-review

MtDNA mutagenesis impairs elimination of mitochondria during erythroid maturation leading to enhanced erythrocyte destruction

Ahlqvist, K. J., Leoncini, S., Pecorelli, A., Wortmann, S. B., Ahola, S., Forsström, S., Guerranti, R., De Felice, C., Smeitink, J., Ciccoli, L., Hämäläinen, R. & Suomalainen, A., Mar 2015, In : Nature Communications. 6, 11 p., 6494.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

Khan, N. A., Auranen, M., Paetau, I., Pirinen, E., Euro, L., Forsström, S., Pasila, L., Velagapudi, V., Carroll, C. J., Auwerx, J. & Suomalainen, A., Jun 2014, In : EMBO molecular medicine. 6, 6, p. 721-731 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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