Research output per year
Research output per year
- 15 results
Search results
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2021
DNA-korjauksen kahdet kasvot : genomin ylläpito ja geenien muokkaus
Ollila, S. & Andressoo, J-O., 2021, In: Duodecim. 137, 10, p. 1073-1081 9 p.Research output: Contribution to journal › Review Article › peer-review
Open AccessFile -
2018
Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway
Ollila, S., Domenech-Moreno, E., Laajanen, K., Wong, I. P. L., Tripathi, S., Pentinmikko, N., Gao, Y., Yan, Y., Niemelä, E. H., Wang, T. C., Viollet, B., Leone, G., Katajisto, P., Vaahtomeri, K. & Mäkelä, T. P., 2 Jan 2018, In: Journal of Clinical Investigation. 128, 1, p. 402-414 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
2017
Western Diet Deregulates Bile Acid Homeostasis, Cell Proliferation, and Tumorigenesis in Colon
Dermadi, D., Valo, S., Ollila, S., Soliymani, R., Sipari, N., Pussila, M., Sarantaus, L., Linden, J., Baumann, M. & Nystrom, M., 15 Jun 2017, In: Cancer Research. 77, 12, p. 3352-3363 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2015
SUMOylation of AMPK alpha 1 by PIAS4 specifically regulates mTORC1 signalling
Yan, Y., Ollila, S., Wong, I. P. L., Vallenius, T., Palvimo, J. J., Vaahtomeri, K. & Mäkelä, T., Nov 2015, In: Nature Communications. 6, 12 p., 8979.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2013
Cancer-Predicting Gene Expression Changes in Colonic Mucosa of Western Diet Fed Mlh1(+/-) Mice
Pussila, M., Sarantaus, L., Dermadi Bebek, D., Valo, S., Reyhani, N., Ollila, S., Päivärinta, E. M-A., Peltomäki, P. T., Mutanen, M. & Nyström, M., 8 Oct 2013, In: PLoS One. 8, 10, 12 p., UNSP e76865.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2011
A putative Lynch syndrome family carrying MSH2 and MSH6 variants of uncertain significance-functional analysis reveals the pathogenic one
Kantelinen, J., Hansen, T. V. O., Kansikas, M., Krogh, L. N., Korhonen, M. K., Ollila, S., Nystrom, M., Gerdes, A-M. & Kariola, R., 2011, In: Familial Cancer. 2011, 10, p. 515-520 6 p.Research output: Contribution to journal › Article › Scientific › peer-review
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The tumor suppressor kinase LKB1: lessons from mouse models
Ollila, S. & Makela, T. P., 2011, In: Journal of Molecular Cell Biology. 3, 6, p. 330-340 11 p.Research output: Contribution to journal › Review Article › peer-review
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2010
MutSbeta exceeds MutSalpha in dinucleotide loop repair
Kantelinen, J., Kansikas, M., Korhonen, M., Ollila, S., Heinimann, K., Kariola, R. & Nyström, M., 2010, In: British Journal of Cancer. 102, 6, p. 1068–1073 6 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2009
Germline MLH1 and MSH2 mutations in Italian pancreatic cancer patients with suspected Lynch syndrome
Gargiulo, S., Torrini, M., Ollila, S., Nasti, S., Pastorino, L., Cusano, R., Bonelli, L., Battistuzzi, L., Mastracci, L., Bruno, W., Savarino, V., Sciallero, S., Borgonovo, G., Nyström, M., Bianchi-Scarra, G., Mareni, C. & Ghiorzo, P., 2009, In: Familial Cancer. 8, 4, p. 547-553 7 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2008
Mechanisms of Pathogenicity in Human MSH2 Missense Mutants
Ollila, S., Dermadi Bebek, D., Jiricny, J. & Nyström, M., 2008, In: Human Mutation. 29, 11, p. 1355-1363 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Pathogenicity, functional significance and clinical phenotype of mismatch repair gene MSH2 variants found in cancer patients
Ollila, S., 2008, Helsinki: University of Helsinki, Department of Biological and Environmental Sciences. 85 p.Research output: Thesis › Doctoral Thesis › Monograph
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Uncertain pathogenicity of MSH2 variants N127S and G322D challenges their classification
Ollila, S., Dermadi Bebek, D., Greenblatt, M. & Nyström, M., 2008, In: International Journal of Cancer. 123, 3, p. 720-724 5 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2007
Interpreting missense variants: comparing computational methods in human disease genes CDKN2A, MLH1, MSH2, MECP2, and Tyrosinase (TYR)
Chan, P. A., Duraisamy, S., Miller, P. J., Newell, J. A., McBride, C., Bond, J. P., Raevaara, T. E., Ollila, S., Nyström, M., Grimm, A. J., Christodoulou, J., Oetting, W. S. & Greenblatt, M. S., 2007, In: Human Mutation. 28, 7, p. 683-693 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2006
Pathogenicity of MSH2 missense mutations is typically associated with impaired repair capability of the mutated protein
Ollila, S., Sarantaus, L., Kariola, R., Chan, P., Hampel, H., Holinski-Feder, E., Macrae, F., Kohonen-Corish, M., Gerdes, A-M., Peltomäki, P., Mangold, E., Chapelle, A. D. L., Greenblatt, M. & Nyström, M., 2006, In: Gastroenterology. 131, p. 1408-1417 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
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The importance of functional testing in the genetic assessment of Muir-Torre syndrome, a clinical subphenotype of HNPCC
Ollila, S., Fitzpatrick, R., Sarantaus, L., Kariola, R., Ambus, I., Velsher, L., Hsieh, E., Klarskov-Andersen, M., Raevaara, T. E., Gerdes, A-M., Mangold, E., Peltomäki, P., Lynch, H. T. & Nyström, M., 2006, In: International Journal of Oncology. 28, p. 149-153 5 p.Research output: Contribution to journal › Article › Scientific › peer-review