Photo of Samuli Ripatti
  • PL 20 (Tukholmankatu 8)

    00014

    Finland

  • Finland

19982019
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Publications 1998 2019

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2019

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

PRACTICAl Consortium, Law, P. J., Timofeeva, M., Fernandez-Rozadilla, C., Palin, K., Hänninen, U. A., Cajuso, T., Tanskanen, T., Kondelin, J., Kaasinen, E., Sarin, A-P., Eriksson, J. G., Jousilahti, P., Ripatti, S., Palotie, A., Renkonen-Sinisalo, L., Lepistö, A., Aaltonen, L. A., Rissanen, H., Salomaa, V. & 3 othersBöhm, J., Mecklin, J-P. & Pukkala, E., 14 May 2019, In : Nature Communications. 10, 15 p., 2154.

Research output: Contribution to journalArticleScientificpeer-review

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Coronary Artery Disease Risk and Lipidomic Profiles Are Similar in Hyperlipidemias With Family History and Population-Ascertained Hyperlipidemias

Ramo, J. T., Ripatti, P., Tabassum, R., Soderlund, S., Matikainen, N., Gerl, M. J., Klose, C., Surma, M. A., Stitziel, N. O., Havulinna, A. S., Pirinen, M., Salomaa, V., Freimer, N. B., Jauhiainen, M., Palotie, A., Taskinen, M-R., Simons, K. & Ripatti, S., 2 Jul 2019, In : Journal of the American Heart Association. 8, 13, 38 p., 012415.

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Disentangling the genetics of lean mass

Karasik, D., Zillikens, M. C., Hsu, Y-H., Aghdassi, A., Akesson, K., Amin, N., Barroso, I., Bennett, D. A., Bertram, L., Bochud, M., Borecki, I. B., Broer, L., Buchman, A. S., Byberg, L., Campbell, H., Campos-Obando, N., Cauley, J. A., Cawthon, P. M., Chambers, J. C., Chen, Z. & 137 othersCho, N. H., Choi, H. J., Chou, W-C., Cummings, S. R., de Groot, L. C. P. G. M., De Jager, P. L., Demuth, I., Diatchenko, L., Econs, M. J., Eiriksdottir, G., Enneman, A. W., Eriksson, J., Eriksson, J. G., Estrada, K., Evans, D. S., Feitosa, M. F., Fu, M., Gieger, C., Grallert, H., Gudnason, V., Lenore, L. J., Hayward, C., Hofman, A., Homuth, G., Huffman, K. M., Husted, L. B., Illig, T., Ingelsson, E., Ittermann, T., Jansson, J-O., Johnson, T., Biffar, R., Jordan, J. M., Jula, A., Karlsson, M., Khaw, K-T., Kilpelainen, T. O., Klopp, N., Kloth, J. S. L., Koller, D. L., Kooner, J. S., Kraus, W. E., Kritchevsky, S., Kutalik, Z., Kuulasmaa, T., Kuusisto, J., Laakso, M., Lahti, J., Lang, T., Langdahl, B. L., Lerch, M. M., Lewis, J. R., Lill, C., Lind, L., Lindgren, C., Liu, Y., Livshits, G., Ljunggren, O., Loos, R. J. F., Lorentzon, M., Luan, J., Luben, R. N., Malkin, I., McGuigan, F. E., Medina-Gomez, C., Meitinger, T., Melhus, H., Mellstrom, D., Michaelsson, K., Mitchell, B. D., Morris, A. P., Mosekilde, L., Nethander, M., Newman, A. B., O'Connell, J. R., Oostra, B. A., Orwoll, E. S., Palotie, A., Peacock, M., Perola, M., Peters, A., Prince, R. L., Psaty, B. M., Räikkönen, K., Ralston, S. H., Ripatti, S., Rivadeneira, F., Robbins, J. A., Rotter, J. I., Rudan, I., Salomaa, V., Satterfield, S., Schipf, S., Shin, C. S., Smith, A. V., Smith, S. B., Soranzo, N., Spector, T. D., Stancakova, A., Stefansson, K., Steinhagen-Thiessen, E., Stolk, L., Streeten, E. A., Styrkarsdottir, U., Swart, K. M. A., Thompson, P., Thomson, C. A., Thorleifsson, G., Thorsteinsdottir, U., Tikkanen, E., Tranah, G. J., Uitterlinden, A. G., van Duijn, C. M., van Schoor, N. M., Vandenput, L., Vollenweider, P., Volzke, H., Wactawski-Wende, J., Walker, M., Wareham, N. J., Waterworth, D., Weedon, M. N., Wichmann, H-E., Widen, E., Williams, F. M. K., Wilson, J. F., Wright, N. C., Yerges-Armstrong, L. M., Yu, L., Zhang, W., Zhao, J. H., Zhou, Y., Nielson, C. M., Harris, T. B., Demissie, S., Kiel, D. P. & Ohlsson, C., Feb 2019, In : American Journal of Clinical Nutrition. 109, 2, p. 276-287 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

Spracklen, C. N., Karaderi, T., Yaghootkar, H., Schurmann, C., Fine, R. S., Kutalik, Z., Preuss, M. H., Lu, Y., Wittemans, L. B. L., Adair, L. S., Allison, M., Amin, N., Auer, P. L., Bartz, T. M., Blueher, M., Boehnke, M., Borja, J. B., Bork-Jensen, J., Broer, L., Chasman, D. I. & 84 othersChen, Y-D. I., Chirstofidou, P., Demirkan, A., van Duijn, C. M., Feitosa, M. F., Garcia, M. E., Graff, M., Grallert, H., Grarup, N., Guo, X., Haesser, J., Hansen, T., Harris, T. B., Highland, H. M., Hong, J., Ikram, M. A., Ingelsson, E., Jackson, R., Jousilahti, P., Kahonen, M., Kizer, J. R., Kovacs, P., Kriebel, J., Laakso, M., Lange, L. A., Lehtimaki, T., Li, J., Ruifang Li-Gao, Lind, L., Luan, J., Lyytikainen, L-P., MacGregor, S., Mackey, D. A., Mahajan, A., Mangino, M., Männistö, S., McCarthy, M. I., McKnight, B., Medina-Gomez, C., Meigs, J. B., Molnos, S., Mook-Kanamori, D., Morris, A. P., de Mutsert, R., Nalls, M. A., Nedeljkovic, I., North, K. E., Pennell, C. E., Pradhan, A. D., Province, M. A., Raitakari, O. T., Raulerson, C. K., Reiner, A. P., Ridker, P. M., Ripatti, S., Roberston, N., Rotter, J. I., Salomaa, V., Sandoval-Zarate, A. A., Sitlani, C. M., Spector, T. D., Strauch, K., Stumvoll, M., Taylor, K. D., Thuesen, B., Toenjes, A., Uitterlinden, A. G., Venturini, C., Walker, M., Wang, C. A., Wang, S., Wareham, N. J., Willems, S. M., van Dijk, K. W., Wilson, J. G., Wu, Y., Yao, J., Young, K. L., Langenberg, C., Frayling, T. M., Kilpelainen, T. O., Lindgren, C. M., Loos, R. J. F. & Mohlke, K. L., 3 Jul 2019, In : American Journal of Human Genetics. 105, 1, p. 15-28 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Exome sequencing of Finnish isolates enhances rare-variant association power

FinnGen Project, Locke, A. E., Havulinna, A. S., Pirinen, M., Eriksson, J. G., Ala-Korpela, M., Järvelin, M-R., Männikkö, M., Laivuori, H., Palotie, A., Salomaa, V., Laakso, M. & Ripatti, S., 15 Aug 2019, In : Nature. 572, 7769, p. 323–+ 21 p.

Research output: Contribution to journalArticleScientificpeer-review

Genetic architecture of human plasma lipidome and its link to cardiovascular disease

Tabassum, R., Rämö, J. T., Ripatti, P., Koskela, J. T., Kurki, M., Karjalainen, J., Palta, P., Hassan, S., Nunez-Fontarnau, J., Kiiskinen, T. T. J., Söderlund, S., Matikainen, N., Gerl, M. J., Surma, M. A., Klose, C., Stitziel, N. O., Laivuori, H., Havulinna, A. S., Service, S. K., Salomaa, V. & 240 othersPirinen, M., Jalanko, A., Kaprio, J., Donner, K., Kaunisto, M., Mars, N., Dada, A., Shcherban, A., Ganna, A., Lehisto, A., Kilpeläinen, E., Brein, G., Awaisa, G., Harju, J., Pärn, K., Parolo, P. D. B., Kajanne, R., Lemmelä, S., Sipilä, T. P., Sipilä, T., Lyhs, U., Llorens, V., Niiranen, T., Kristiansson, K., Männikkö, L., Jiménez, M. G., Perola, M., Wong, R., Kilpi, T., Hiekkalinna, T., Järvensivu, E., Kaiharju, E., Mattsson, H., Laukkanen, M., Laiho, P., Lähteenmäki, S., Sistonen, T., Soini, S., Ziemann, A., Lehtonen, A., Lertratanakul, A., Georgantas, B., Riley-Gillis, B., Quarless, D., Rahimov, F., Heap, G., Jacob, H., Waring, J., Davis, J. W., Smaoui, N., Popovic, R., Esmaeeli, S., Waring, J., Matakidou, A., Challis, B., Close, D., Petrovski, S., Karlsson, A., Schleutker, J., Pulkki, K., Virolainen, P., Kallio, L., Mannermaa, A., Heikkinen, S., Kosma, V-M., Chen, C-Y., Runz, H., Liu, J., Bronson, P., John, S., Lahdenperä, S., Eaton, S., Zhou, W., Hendolin, M., Tuovila, O., Pakkanen, R., Maranville, J., Usiskin, K., Hochfeld, M., Plenge, R., Yang, R., Biswas, S., Greenberg, S., Laakkonen, E., Kononen, J., Paloneva, J., Kujala, U., Kuopio, T., Laukkanen, J., Kangasniemi, E., Savinainen, K., Laaksonen, R., Arvas, M., Ritari, J., Partanen, J., Hyvärinen, K., Wahlfors, T., Peterson, A., Oh, D., Chang, D., Teng, E., Strauss, E., Kerchner, G., Chen, H., Chen, H., Schutzman, J., Michon, J., Hunkapiller, J., McCarthy, M., Bowers, N., Lu, T., Bhangale, T., Pulford, D., Waterworth, D., Kulkarni, D., Xu, F., Betts, J., Gordillo, J. E., Hoffman, J., Auro, K., McCarthy, L., Ghosh, S., Ehm, M., Pitkänen, K., Mäkelä, T., Loukola, A., Joensuu, H., Sinisalo, J., Eklund, K., Aaltonen, L., Färkkilä, M., Carpen, O., Kauppi, P., Tienari, P., Ollila, T., Tuomi, T., Meretoja, T., Pitkäranta, A., Turunen, J., Hannula-Jouppi, K., Pikkarainen, S., Seitsonen, S., Koskinen, M., Palomäki, A., Rinne, J., Metsärinne, K., Elenius, K., Pirilä, L., Koulu, L., Voutilainen, M., Juonala, M., Peltonen, S., Aaltonen, V., Loboda, A., Podgornaia, A., Chhibber, A., Chu, A., Fox, C., Diogo, D., Holzinger, E., Eicher, J., Gormley, P., Mehta, V., Wang, X., Kettunen, J., Pylkäs, K., Kalaoja, M., Karjalainen, M., Hinttala, R., Kaarteenaho, R., Vainio, S., Mantere, T., Remes, A., Huhtakangas, J., Junttila, J., Tasanen, K., Huilaja, L., Luodonpää, M., Hautala, N., Karihtala, P., Kauppila, S., Harju, T., Blomster, T., Soininen, H., Harvima, I., Pihlajamäki, J., Kaarniranta, K., Pelkonen, M., Laakso, M., Hiltunen, M., Kiviniemi, M., Kaipiainen-Seppänen, O., Auvinen, P., Kälviäinen, R., Julkunen, V., Malarstig, A., Hedman, Å., Marshall, C., Whelan, C., Lehtonen, H., Parkkinen, J., Linden, K., Kalpala, K., Miller, M., Bing, N., McDonough, S., Chen, X., Hu, X., Wu, Y., Auranen, A., Jussila, A., Uusitalo-Järvinen, H., Kankaanranta, H., Uusitalo, H., Peltola, J., Kähönen, M., Isomäki, P., Laitinen, T., Salmi, T., Muslin, A., Wang, C., Chatelain, C., Xu, E., Auge, F., Call, K., Klinger, K., Crohns, M., Gossel, M., Palin, K., Rivas, M., Siirtola, H., Tabuenca, J. G., Jauhiainen, M., Daly, M. J., Freimer, N. B., Palotie, A., Taskinen, M-R., Simons, K., Ripatti, S. & Project, F., 24 Sep 2019, In : Nature Communications. 10, 1

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Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

23and Me Res Team, eQTLGen Consortium, Int Cannabis Consortium, Soc Sci Genetic Association Con, Linner, R. K., Perola, M., Ripatti, S., Gupta, R., Lahti, J., Eklund, N., Koskinen, S., Latvala, A., Loukola, A., Mäki-Opas, T., Palotie, A., Sarin, A-P., Räikkönen, K., Eriksson, J. G., Kaprio, J., Perola, M. & 3 othersSalomaa, V., Kaasik, K. & Keltikangas-Järvinen, L., Feb 2019, In : Nature Genetics. 51, 2, p. 245-+ 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

Anorexia Nervosa Genetics Initiati, Psychiat Genomics Consortium, Watson, H. J., Yilmaz, Z., Kaprio, J., Keski-Rahkonen, A., Palotie, A., Raevuori, A., Ripatti, S. & Widen, E., Aug 2019, In : Nature Genetics. 51, 8, p. 1207-+ 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Genome-wide association study in Finnish twins highlights the connection between nicotine addiction and neurotrophin signaling pathway

Hällfors, J., Palviainen, T., Surakka, I., Gupta, R., Buchwald, J., Raevuori, A., Ripatti, S., Korhonen, T., Jousilahti, P., Madden, P. A. F., Kaprio, J. & Loukola, A., May 2019, In : Addiction Biology. 24, 3, p. 549-561 13 p.

Research output: Contribution to journalArticleScientificpeer-review

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Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

eQTLGen Consortium, Timmers, P. R. H. J., Kettunen, J., Perola, M. & Ripatti, S., 15 Jan 2019, In : eLife. 8, 40 p., 39856.

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Geographic Variation and Bias in the Polygenic Scores of Complex Diseases and Traits in Finland

Kerminen, S., Martin, A. R., Koskela, J., Ruotsalainen, S. E., Havulinna, A. S., Surakka, I., Palotie, A., Perola, M., Salomaa, V., Daly, M. J., Ripatti, S. & Pirinen, M., 6 Jun 2019, In : American Journal of Human Genetics. 104, 6, p. 1169-1181 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study

van Essen, T. A., den Boogert, H. F., Cnossen, M. C., CENTER-TBI Investigators Partici, Kaukonen, M., Kivisaari, R., Piippo-Karjalainen, A., Raj, R., Tanskanen, P., Palotie, A., Pirinen, M. & Ripatti, S., Mar 2019, In : Acta Neurochirurgica. 161, 3, p. 435-449 15 p.

Research output: Contribution to journalArticleScientificpeer-review

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2018

Analysis of shared heritability in common disorders of the brain

Brainstorm Consortium, Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y. & 33 othersBerr, C., Letenneur, L., Hannequin, D., Amouyel, P., Boland, A., Deleuze, J-F., Duron, E., Vardarajan, B. N., Reitz, C., Goate, A. M., Huentelman, M. J., Kamboh, M. I., Larson, E. B., Rogaeva, E., St George-Hyslop, P., Hakonarson, H., Kukull, W. A., Palta, P., Wedenoja, J., Artto, V., Kaunisto, M., Vepsäläinen, S., Kurki, M. I., Hämäläinen, E., Kaprio, J., Metspalu, A., Keski-Rahkonen, A., Raevuori, A., Ripatti, S., Lönnqvist, J., Daly, M., Palotie, A. & Neale, B. M., 22 Jun 2018, In : Science. 360, 6395, p. 1313-+ 13 p., 8757.

Research output: Contribution to journalArticleScientificpeer-review

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Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families

23 Me Res Team, IHGC, Gormley, P., Kurki, M. I., Hiekkala, M. E., Häppölä, P., Palta, P., Surakka, I., Kaunisto, M. A., Hämäläinen, E., Vepsäläinen, S., Havanka, H., Harno, H., Ilmavirta, M., Nissilä, M., Säkö, E., Sumelahti, M-L., Liukkonen, J., Sillanpaa, M., Metsähonkala, L. & 15 othersKoskinen, S., Lehtimaki, T., Raitakari, O., Männikko, M., Jousilahti, P., Anttila, V., Salomaa, V., Artto, V., Färkkilä, M., Daly, M. J., Neale, B. M., Ripatti, S., Kallela, M., Wessman, M. & Palotie, A., 16 May 2018, In : Neuron. 98, 4, p. 743–753 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

NHLBI TOPMED Lipids Working Grp, 23 Aug 2018, In : Nature Communications. 9, 12 p., 3391.

Research output: Contribution to journalArticleScientificpeer-review

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Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

NHLBI TOPMED Lipids Working Grp, 4 Jul 2018, In : Nature Communications. 9, 14 p., 2606.

Research output: Contribution to journalArticleScientificpeer-review

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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Million Vet Program, Oct 2018, In : Nature Genetics. 50, 10, p. 1412-+ 17 p.

Research output: Contribution to journalArticleScientificpeer-review

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Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes

Xue, A., Wu, Y., Zhu, Z., Zhang, F., Kemper, K. E., Zheng, Z., Yengo, L., Lloyd-Jones, L. R., Sidorenko, J., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A., Awadalla, P., Battle, A., Beutner, F., Bonder, M. J., Boomsma, D., Christiansen, M., Claringbould, A. & 62 othersDeelen, P., Esko, T., Favé, M-J., Franke, L., Frayling, T., Gharib, S., Gibson, G., Hemani, G., Jansen, R., Kähönen, M., Kalnapenkis, A., Kasela, S., Kettunen, J., Kim, Y., Kirsten, H., Kovacs, P., Krohn, K., Kronberg-Guzman, J., Kukushkina, V., Kutalik, Z., Lee, B., Lehtimäki, T., Loeffler, M., Marigorta, U. M., Metspalu, A., Milani, L., Müller-Nurasyid, M., Nauck, M., Nivard, M., Penninx, B., Perola, M., Pervjakova, N., Pierce, B., Powell, J., Prokisch, H., Psaty, B., Raitakari, O., Ring, S., Ripatti, S., Rotzschke, O., Ruëger, S., Saha, A., Scholz, M., Schramm, K., Seppälä, I., Stumvoll, M., Sullivan, P., Teumer, A., Thiery, J., Tong, L., Tönjes, A., van Dongen, J., van Meurs, J., Verlouw, J., Völker, U., Võsa, U., Yaghootkar, H., Zeng, B., McRae, A. F., Visscher, P. M., Zeng, J. & Yang, J., 2018, In : Nature Communications. 9, 1, 14 p., 2941.

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Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci

Tanskanen, T., van den Berg, L., Valimaki, N., Aavikko, M., Ness-Jensen, E., Hveem, K., Wettergren, Y., Lindskog, E. B., Tonisson, N., Metspalu, A., Silander, K., Orlando, G., Law, P. J., Tuupanen, S., Gylfe, A. E., Hanninen, U. A., Cajuso, T., Kondelin, J., Sarin, A-P., Pukkala, E. & 40 othersJousilahti, P., Salomaa, V., Ripatti, S., Palotie, A., Jarvinen, H., Renkonen-Sinisalo, L., Lepisto, A., Bohm, J., Mecklin, J-P., Al-Tassan, N. A., Palles, C., Martin, L., Barclay, E., Tenesa, A., Farrington, S. M., Timofeeva, M. N., Meyer, B. F., Wakil, S. M., Campbell, H., Smith, C. G., Idziaszczyk, S., Maughan, T. S., Kaplan, R., Kerr, R., Kerr, D., Buchanan, D. D., Win, A. K., Hopper, J., Jenkins, M. A., Newcomb, P. A., Gallinger, S., Conti, D., Schumacher, F. R., Casey, G., Cheadle, J. P., Dunlop, M. G., Tomlinson, I. P., Houlston, R. S., Palin, K. & Aaltonen, L. A., 1 Feb 2018, In : International Journal of Cancer. 142, 3, p. 540-546 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

Jiang, X., O'Reilly, P. F., Aschard, H., Hsu, Y-H., Richards, J. B., Dupuis, J., Ingelsson, E., Karasik, D., Pilz, S., Berry, D., Kestenbaum, B., Zheng, J., Luan, J., Sofianopoulou, E., Streeten, E. A., Albanes, D., Lutsey, P. L., Yao, L., Tang, W., Econs, M. J. & 84 othersWallaschofski, H., Voelzke, H., Zhou, A., Power, C., McCarthy, M. I., Michos, E. D., Boerwinkle, E., Weinstein, S. J., Freedman, N. D., Huang, W-Y., Van Schoor, N. M., van der Velde, N., de Groot, L. C. P. G. M., Enneman, A., Cupples, L. A., Booth, S. L., Vasan, R. S., Liu, C-T., Zhou, Y., Ripatti, S., Ohlsson, C., Vandenput, L., Lorentzon, M., Eriksson, J. G., Shea, M. K., Houston, D. K., Kritchevsky, S. B., Liu, Y., Lohman, K. K., Ferrucci, L., Peacock, M., Gieger, C., Beekman, M., Slagboom, E., Deelen, J., van Heemst, D., Kleber, M. E., Maerz, W., de Boer, I. H., Wood, A. C., Rotter, J. I., Rich, S. S., Robinson-Cohen, C., den Heijer, M., Jarvelin, M-R., Cavadino, A., Joshi, P. K., Wilson, J. F., Hayward, C., Lind, L., Michaelsson, K., Trompet, S., Zillikens, M. C., Uitterlinden, A. G., Rivadeneira, F., Broer, L., Zgaga, L., Campbell, H., Theodoratou, E., Farrington, S. M., Timofeeva, M., Dunlop, M. G., Valdes, A. M., Tikkanen, E., Lehtimaki, T., Lyytikainen, L-P., Kahonen, M., Raitakari, O. T., Mikkila, V., Ikram, M. A., Sattar, N., Jukema, J. W., Wareham, N. J., Langenberg, C., Forouhi, N. G., Gundersen, T. E., Khaw, K-T., Butterworth, A. S., Danesh, J., Spector, T., Wang, T. J., Hypponen, E., Kraft, P. & Kiel, D. P., 17 Jan 2018, In : Nature Communications. 9, 12 p., 260.

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Genomitiedon arkaluonteisuus on tiukassa elävä myytti

Palotie, A., Kaunisto, M., Kääriäinen, H., Perola, M., Pitkänen, K., Ripatti, S., Soini, S. & Widén, E., 2018, In : Suomen lääkärilehti. 73, 15, p. 916-917 2 p.

Research output: Contribution to journalArticleProfessional

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Haplotype Sharing Provides Insights into Fine-Scale Population History and Disease in Finland

Martin, A. R., Karczewski, K. J., Kerminen, S., Kurki, M. I., Sarin, A-P., Artomov, M., Eriksson, J. G., Esko, T., Genovese, G., Havulinna, A. S., Kaprio, J., Konradi, A., Korányi, L., Kostareva, A., Männikkö, M., Metspalu, A., Perola, M., Prasad, R. B., Raitakari, O., Rotar, O. & 7 othersSalomaa, V., Groop, L., Palotie, A., Neale, B. M., Ripatti, S., Pirinen, M. & Daly, M. J., 3 May 2018, In : American Journal of Human Genetics. 102, 5, p. 760-775 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

eQTLGen Consortium, 2018, In : Nature Communications. 9, 1

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Obstructive sleep apnoea and the risk for coronary heart disease and type 2 diabetes: a longitudinal population-based study in Finland

Strausz, S., Havulinna, A. S., Tuomi, T., Bachour, A., Groop, L., Mäkitie, A., Koskinen, S., Salomaa, V., Palotie, A., Ripatti, S. & Palotie, T., Oct 2018, In : BMJ Open. 8, 10, 8 p., 022752.

Research output: Contribution to journalArticleScientificpeer-review

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Phenome-wide association studies across large population cohorts support drug target validation

23andMe Res Team, 16 Oct 2018, In : Nature Communications. 9, 13 p., 4285.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum

GoT2D T2D-GENES Consortium, SIGMA Consortium Helmsley IBD Exom, FinMetSeq Consortium, iPSYCH-Broad Consortium, Ganna, A., Kurki, M., Havulinna, A. S., Saarentaus, E., Ripatti, S., Hämäläinen, E., Moilanen, J. S., Kuismin, O., Palotie, A. & Neale, B. M., 7 Jun 2018, In : American Journal of Human Genetics. 102, 6, p. 1204-1211 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

23andMe Res Team & Räikkönen, K., Dec 2018, In : Nature Neuroscience. 21, 12, p. 1656-+ 16 p.

Research output: Contribution to journalArticleScientificpeer-review

2017

A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling

Li, D., Chang, X., Connolly, J. J., Tian, L., Liu, Y., Bhoj, E. J., Robinson, N., Abrams, D., Li, Y. R., Bradfield, J. P., Kim, C. E., Li, J., Wang, F., Snyder, J., Lemma, M., Hou, C., Wei, Z., Guo, Y., Qiu, H., Mentch, F. D. & 12 othersThomas, K. A., Chiavacci, R. M., Cone, R., Li, B., Sleiman, P. A., Hakonarson, H., Eating Disorders Working Group of the Psychiatric Genomics Consortium, Kaprio, J., Palotie, A., Raevuori-Helkamaa, A., Ripatti, S. & Price Fdn Collaborative Grp, 19 Jun 2017, In : Scientific Reports. 7, 9 p., 3847.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Vinuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 243 othersTeslovich, T. M., Blackwell, T. W., Bork-Jensen, J., Burtt, N. P., Chen, Y., Green, T., Hartl, C., Kang, H. M., Kumar, A., Ladenvall, C., Ma, C., Moutsianas, L., Pearson, R. D., Perry, J. R. B., Rayner, N. W., Robertson, N. R., Scott, L. J., van de Bunt, M., Eriksson, J. G., Jula, A., Koskinen, S., Lehtimaki, T., Palotie, A., Raitakari, O. T., Jacobs, S. B. R., Wessel, J., Chu, A. Y., Scott, R. A., Goodarzi, M. O., Blancher, C., Buck, G., Buck, D., Chines, P. S., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Trakalo, J., Banks, E., Carey, J., Carneiro, M. O., DePristo, M., Farjoun, Y., Fennell, T., Goldstein, J. I., Grant, G., de Angelis, M. H., Maguire, J., Neale, B. M., Poplin, R., Purcell, S., Schwarzmayr, T., Shakir, K., Smith, J. D., Strom, T. M., Wieland, T., Lindstrom, J., Brandslund, I., Christensen, C., Surdulescu, G. L., Lakka, T. A., Doney, A. S. F., Nilsson, P., Wareham, N. J., Langenberg, C., Varga, T. V., Franks, P. W., Rolandsson, O., Rosengren, A. H., Farook, V. S., Thameem, F., Puppala, S., Kumar, S., Lehman, D. M., Jenkinson, C. P., Curran, J. E., Hale, D. E., Fowler, S. P., Arya, R., DeFronzo, R. A., Abboud, H. E., Syvanen, A-C., Hicks, P. J., Palmer, N. D., Ng, M. C. Y., Bowden, D. W., Freedman, B. I., Esko, T., Magi, R., Milani, L., Mihailov, E., Metspalu, A., Narisu, N., Kinnunen, L., Bonnycastle, L. L., Swift, A., Pasko, D., Wood, A. R., Fadista, J., Pollin, T. I., Barzilai, N., Atzmon, G., Glaser, B., Thorand, B., Strauch, K., Peters, A., Roden, M., Mueller-Nurasyid, M., Liang, L., Kriebel, J., Illig, T., Grallert, H., Gieger, C., Meisinger, C., Lannfelt, L., Musani, S. K., Griswold, M., Taylor, H. A., Wilson, G., Correa, A., Oksa, H., Scott, W. R., Afzal, U., Tan, S-T., Loh, M., Chambers, J. C., Sehmi, J., Kooner, J. S., Lehne, B., Cho, Y. S., Lee, J-Y., Han, B-G., Karajamaki, A., Qi, Q., Qi, L., Huang, J., Hu, F. B., Melander, O., Orho-Melander, M., Below, J. E., Aguilar, D., Wong, T. Y., Liu, J., Khor, C-C., Chia, K. S., Lim, W. Y., Cheng, C-Y., Chan, E., Tai, E. S., Aung, T., Linneberg, A., Isomaa, B., Meitinger, T., Tuomi, T., Hakaste, L., Kravic, J., Jorgensen, M. E., Lauritzen, T., Deloukas, P., Stirrups, K. E., Owen, K. R., Farmer, A. J., Frayling, T. M., O'Rahilly, S. P., Walker, M., Levy, J. C., Hodgkiss, D., Hattersley, A. T., Kuulasmaa, T., Stancakova, A., Barroso, I., Bharadwaj, D., Chan, J., Chandak, G. R., Daly, M. J., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Fingerlin, T., Froguel, P., Hu, C., Jia, W., Ma, R. C. W., McVean, G., Park, T., Prabhakaran, D., Sandhu, M., Scott, J., Sladek, R., Tandon, N., Teo, Y. Y., Zeggini, E., Watanabe, R. M., Koistinen, H. A., Kesaniemi, Y. A., Uusitupa, M., Spector, T. D., Salomaa, V., Rauramaa, R., Palmer, C. N. A., Prokopenko, I., Morris, A. D., Bergman, R. N., Collins, F. S., Lind, L., Ingelsson, E., Tuomilehto, J., Karpe, F., Groop, L., Jorgensen, T., Hansen, T., Pedersen, O., Kuusisto, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Seielstad, M., Wilson, J. G., Dupuis, J., Ripatti, S., Hanis, C. L., Florez, J. C., Mohlke, K. L., Meigs, J. B., Laakso, M., Morris, A. P., Boehnke, M., Altshuler, D., McCarthy, M. I., Gloyn, A. L. & Lindgren, C. M., 1 Jul 2017, In : Diabetes. 66, 7, p. 2019-2032 14 p.

Research output: Contribution to journalArticleScientificpeer-review

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Scott, R. A., Scott, L. J., Maegi, R., Marullo, L., Gaulton, K. J., Kaakinen, M., Pervjakova, N., Pers, T. H., Johnson, A. D., Eicher, J. D., Jackson, A. U., Ferreira, T., Lee, Y., Ma, C., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Van Zuydam, N. R., Mahajan, A., Chen, H. & 31 othersAlmgren, P., Voight, B. F., Grallert, H., Mueller-Nurasyid, M., Ried, J. S., Rayner, N. W., Robertson, N., Karssen, L. C., Van Leeuwen, E. M., Willems, S. M., Fuchsberger, C., Kwan, P., Teslovich, T. M., Chanda, P., Li, M., Lu, Y., Dina, C., Thuillier, D., Yengo, L., Jiang, L., Chheda, H., Tuomi, T., Koistinen, H. A., Kinnunen, L., Eriksson, J. G., Peltonen, L., Tikkanen, E., Ripatti, S., Tuomilehto, J., Groop, L. C. & Diabetes Genetics Replicat, 1 Nov 2017, In : Diabetes. 66, 11, p. 2888-2902 15 p.

Research output: Contribution to journalArticleScientificpeer-review

An interaction map of circulating metabolites, immune gene networks, and their genetic regulation

Nath, A. P., Ritchie, S. C., Byars, S. G., Fearnley, L. G., Havulinna, A. S., Joensuu, A., Kangas, A. J., Soininen, P., Wennerstrom, A., Milani, L., Metspalu, A., Mannisto, S., Wurtz, P., Kettunen, J., Raitoharju, E., Kahonen, M., Juonala, M., Palotie, A., Ala-Korpela, M., Ripatti, S. & 6 othersLehtimaki, T., Abraham, G., Raitakari, O., Salomaa, V., Perola, M. & Inouye, M., 1 Aug 2017, In : Genome Biology. 18, 15 p., 146.

Research output: Contribution to journalArticleScientificpeer-review

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biMM: efficient estimation of genetic variances and covariances for cohorts with high-dimensional phenotype measurements

Pirinen, M., Benner, C., Marttinen, P., Jarvelin, M-R., Rivas, M. A. & Ripatti, S., 1 Aug 2017, In : Bioinformatics. 33, 15, p. 2405-2407 3 p.

Research output: Contribution to journalArticleScientificpeer-review

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Clinical Prediction Model and Tool for Assessing Risk of Persistent Pain After Breast Cancer Surgery

Meretoja, T. J., Andersen, K. G., Bruce, J., Haasio, L., Sipilä, R., Scott, N. W., Ripatti, S., Kehlet, H. & Kalso, E., 20 May 2017, In : Journal of Clinical Oncology. 35, 15, p. 1660-+ 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Does expecting more pain make it more intense? Factors associated with the first week pain trajectories after breast cancer surgery

Sipila, R. M., Haasio, L., Meretoja, T. J., Ripatti, S., Estlander, A-M. & Kalso, E. A., May 2017, In : Pain. 158, 5, p. 922-930 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations

Xue, Y., Mezzavilla, M., Haber, M., McCarthy, S., Chen, Y., Narasimhan, V., Gilly, A., Ayub, Q., Colonna, V., Southam, L., Finan, C., Massaia, A., Chheda, H., Palta, P., Ritchie, G., Asimit, J., Dedoussis, G., Gasparini, P., Palotie, A., Ripatti, S. & 6 othersSoranzo, N., Toniolo, D., Wilson, J. F., Durbin, R., Tyler-Smith, C. & Zeggini, E., 23 Jun 2017, In : Nature Communications. 8, 7 p., 15927.

Research output: Contribution to journalArticleScientificpeer-review

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Family aggregation of cardiovascular disease mortality: a register-based prospective study of pooled Nordic twin cohorts

Silventoinen, K., Hjelmborg, J., Moller, S., Ripatti, S., Skythe, A., Tikkanen, E., Pedersen, N. L., Magnusson, P. K. E., Christensen, K. & Kaprio, J., Aug 2017, In : International Journal of Epidemiology. 46, 4, p. 1223-1229 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Fine-Scale Genetic Structure in Finland

Kerminen, S., Havulinna, A. S., Hellenthal, G., Martin, A. R., Sarin, A-P., Perola, M., Palotie, A., Salomaa, V., Daly, M. J., Ripatti, S. & Pirinen, M., Oct 2017, In : G3 - Genes genomes genetics. 7, 10, p. 3459-3468 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy

Byars, S. G., Huang, Q. Q., Gray, L-A., Bakshi, A., Ripatti, S., Abraham, G., Stearns, S. C. & Inouye, M., Jun 2017, In : PLoS Genetics. 13, 6, 27 p., 1006328.

Research output: Contribution to journalArticleScientificpeer-review

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Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

Warren, H. R., Evangelou, E., Cabrera, C. P., Gao, H., Ren, M., Mifsud, B., Ntalla, I., Surendran, P., Liu, C., Cook, J. P., Kraja, A. T., Drenos, F., Loh, M., Verweij, N., Marten, J., Karaman, I., Lepe, M. P. S., O'Reilly, P. F., Knight, J., Snieder, H. & 284 othersKato, N., He, J., Tai, E. S., Said, M. A., Porteous, D., Alver, M., Poulter, N., Farrall, M., Gansevoort, R. T., Padmanabhan, S., Magi, R., Stanton, A., Connell, J., Bakker, S. J. L., Metspalu, A., Shields, D. C., Thom, S., Brown, M., Sever, P., Esko, T., Hayward, C., van der Harst, P., Saleheen, D., Chowdhury, R., Chambers, J. C., Chasman, D. I., Chakravarti, A., Newton-Cheh, C., Lindgren, C. M., Levy, D., Kooner, J. S., Keavney, B., Tomaszewski, M., Samani, N. J., Howson, J. M. M., Tobin, M. D., Munroe, P. B., Ehret, G. B., Wain, L. V., Barnes, M. R., Tzoulaki, J., Caulfield, M. J., Elliott, P., Wain, L. V., Vaez, A., Jansen, R., Joehanes, R., van der Most, P. J., Erzurumluoglu, A. M., O'Reilly, P., Cabrera, C. P., Warren, H. R., Rose, L. M., Verwoert, G. C., Hottenga, J-J., Strawbridge, R. J., Esko, T., Arking, D. E., Hwang, S-J., Guo, X., Kutalik, Z., Trompet, S., Shrine, N., Teumer, A., Ried, J. S., Bis, J. C., Smith, A. V., Amin, N., Nolte, I. M., Lyytikainen, L-P., Mahajan, A., Wareham, N. J., Hofer, E., Joshi, P. K., Kristiansson, K., Traglia, M., Havulinna, A. S., Goel, A., Nalls, M. A., Sober, S., Vuckovic, D., Luan, J., Del Greco M, F., Ayers, K. L., Marrugat, J., Ruggiero, D., Lopez, L. M., Niiranen, T., Enroth, S., Jackson, A. U., Nelson, C. P., Huffman, J. E., Zhang, W., Marten, J., Gandin, I., Harris, S. E., Zemonik, T., Lu, Y., Evangelou, E., Shah, N., de Borst, M. H., Mangino, M., Prins, B. P., Campbell, A., Li-Gao, R., Chauhan, G., Oldmeadow, C., Abecasis, G., Abedi, M., Barbieri, C. M., Barnes, M. R., Batini, C., Blake, T., Boehnke, M., Bottinger, E. P., Braund, P. S., Brown, M., Brumat, M., Campbell, H., Chambers, J. C., Cocca, M., Collins, F., Connell, J., Cordell, H. J., Damman, J. J., Davies, G., de Geus, E. J., de Mutsert, R., Deelen, J., Demirkale, Y., Doney, A. S. F., Dorr, M., Farrall, M., Ferreira, T., Franberg, M., Gao, H., Giedraitis, V., Gieger, C., Giulianini, F., Gow, A. J., Hamsten, A., Harris, T. B., Hofman, A., Holliday, E. G., Jarvelin, M-R., Johansson, A., Johnson, A. D., Jousilahti, P., Jula, A., Kahonen, M., Kathiresan, S., Khaw, K-T., Kolcic, I., Koskinen, S., Langenberg, C., Larson, M., Launer, L. J., Lehne, B., Liewald, D. C. M., Lin, L., Lind, L., Mach, F., Mamasoula, C., Menni, C., Mifsud, B., Milaneschi, Y., Morgan, A., Morris, A. D., Morrison, A. C., Munson, P. J., Nandakumar, P., Quang Tri Nguyen, Nutile, T., Oldehinkel, A. J., Oostra, B. A., Org, E., Padmanabhan, S., Palotie, A., Pare, G., Pattie, A., Penninx, B. W. J. H., Poulter, N., Pramstaller, P. P., Raitakari, O. T., Ren, M., Rice, K., Ridker, P. M., Riese, H., Ripatti, S., Robino, A., Rotter, J. I., Rudan, I., Saba, Y., Saint Pierre, A., Sala, C. F., Sarin, A-P., Schmidt, R., Scott, R., Seelen, M. A., Shields, D. C., Siscovick, D., Sorice, R., Stanton, A., Stott, D. J., Sundstrom, J., Swertz, M., Taylor, K. D., Thom, S., Tzoulaki, I., Tzourio, C., Uitterlinden, A. G., Volker, U., Vollenweider, P., Wild, S., Willemsen, G., Wright, A. F., Yao, J., Theriault, S., Conen, D., John, A., Sever, P., Debette, S., Mook-Kanamori, D. O., Zeggini, E., Spector, T. D., van der Harst, P., Palmer, C. N. A., Vergnaud, A-C., Loos, R. J. F., Polasek, O., Starr, J. M., Girotto, G., Hayward, C., Kooner, J. S., Lindgren, C. M., Vitart, V., Samani, N. J., Tuomilehto, J., Gyllensten, U., Knekt, P., Deary, I. J., Ciullo, M., Elosua, R., Keavney, B. D., Hicks, A. A., Scott, R. A., Gasparini, P., Laan, M., Liu, Y., Watkins, H., Hartman, C. A., Salomaa, V., Toniolo, D., Perola, M., Wilson, J. F., Schmidt, H., Zhao, J. H., Lehtimaki, T., van Duijn, C. M., Gudnason, V., Psaty, B. M., Peters, A., Rettig, R., James, A., Jukema, J. W., Strachan, D. P., Palmas, W., Metspalu, A., Ingelsson, E., Boomsma, D. I., Franco, O. H., Bochud, M., Newton-Cheh, C., Munroe, P. B., Elliott, P., Chasman, D. I., Chakravarti, A., Knight, J., Morris, A. P., Levy, D., Tobin, M. D., Snieder, H., Caulfield, M. J. & Ehret, G. B., Mar 2017, In : Nature Genetics. 49, 3, p. 403-415 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors

Ahola-Olli, A. V., Wurtz, P., Havulinna, A. S., Aalto, K., Pitkanen, N., Lehtimaki, T., Kahonen, M., Lyytikainen, L-P., Raitoharju, E., Seppala, I., Sarin, A-P., Ripatti, S., Palotie, A., Perola, M., Viikari, J. S., Jalkanen, S., Maksimow, M., Salomaa, V., Salmi, M., Kettunen, J. & 1 othersRaitakari, O. T., 5 Jan 2017, In : American Journal of Human Genetics. 100, 1, p. 40-50 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

Zhao, W., Rasheed, A., Tikkanen, E., Lee, J-J., Butterworth, A. S., Howson, J. M. M., Assimes, T. L., Chowdhury, R., Orho-Melander, M., Damrauer, S., Small, A., Asma, S., Imamura, M., Yamauch, T., Chambers, J. C., Chen, P., Sapkota, B. R., Shah, N., Jabeen, S., Surendran, P. & 33 othersLu, Y., Zhang, W., Imran, A., Abbas, S., Majeed, F., Trindade, K., Qamar, N., Mallick, N. H., Yaqoob, Z., Saghir, T., Rizvi, S. N. H., Memon, A., Rasheed, S. Z., Memon, F-R., Mehmood, K., Ahmed, N., Qureshi, I. H., Tanveer-us-Salam, Iqbal, W., Malik, U., Mehra, N., Kuo, J. Z., Sheu, W. H-H., Guo, X., Hsiung, C. A., Juang, J-M. J., Taylor, K. D., Hung, Y-J., Lee, W-J., Ripatti, S., CHD Exome Consortium, EPIC-CVD Consortium & EPIC-Interact Consortium, Oct 2017, In : Nature Genetics. 49, 10, p. 1450-+ 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel

Mitt, M., Kals, M., Parn, K., Gabriel, S. B., Lander, E. S., Palotie, A., Ripatti, S., Morris, A. P., Metspalu, A., Esko, T., Magi, R. & Palta, P., Jun 2017, In : European Journal of Human Genetics. 25, 7, p. 869-876 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

Zillikens, M. C., Demissie, S., Hsu, Y-H., Yerges-Armstrong, L. M., Chou, W-C., Stolk, L., Livshits, G., Broer, L., Johnson, T., Koller, D. L., Kutalik, Z., Luan, J., Malkin, I., Ried, J. S., Smith, A. V., Thorleifsson, G., Vandenput, L., Zhao, J. H., Zhang, W., Aghdassi, A. & 173 othersAkesson, K., Amin, N., Baier, L. J., Barroso, I., Bennett, D. A., Bertram, L., Biffar, R., Bochud, M., Boehnke, M., Borecki, I. B., Buchman, A. S., Byberg, L., Campbell, H., Obanda, N. C., Cauley, J. A., Cawthon, P. M., Cederberg, H., Chen, Z., Cho, N. H., Choi, H. J., Claussnitzer, M., Collins, F., Cummings, S. R., De Jager, P. L., Demuth, I., Dhonukshe-Rutten, R. A. M., Diatchenko, L., Eiriksdottir, G., Enneman, A. W., Erdos, M., Eriksson, J. G., Eriksson, J., Estrada, K., Evans, D. S., Feitosa, M. F., Fu, M., Garcia, M., Gieger, C., Girke, T., Glazer, N. L., Grallert, H., Grewal, J., Han, B-G., Hanson, R. L., Hayward, C., Hofman, A., Hoffman, E. P., Homuth, G., Hsueh, W-C., Hubal, M. J., Hubbard, A., Huffman, K. M., Husted, L. B., Illig, T., Ingelsson, E., Ittermann, T., Jansson, J-O., Jordan, J. M., Jula, A., Karlsson, M., Khaw, K-T., Kilpainen, T. O., Klopp, N., Kloth, J. S. L., Koistinen, H. A., Kraus, W. E., Kritchevsky, S., Kuulasmaa, T., Kuusisto, J., Laakso, M., Lahti, J., Lang, T., Langdahl, B. L., Launer, L. J., Lee, J-Y., Lerch, M. M., Lewis, J. R., Lind, L., Lindgren, C., Liu, Y., Liu, T., Liu, Y., Ljunggren, O., Lorentzon, M., Luben, R. N., Maixner, W., McGuigan, F. E., Medina-Gomez, C., Meitinger, T., Melhus, H., Mellstrom, D., Melov, S., Michaelsson, K., Mitchell, B. D., Morris, A. P., Mosekilde, L., Newman, A., Nielson, C. M., O'Connell, J. R., Oostra, B. A., Orwoll, E. S., Palotie, A., Parker, S. C. J., Peacock, M., Perola, M., Peters, A., Polasek, O., Prince, R. L., Raikkonen, K., Ralston, S. H., Ripatti, S., Robbins, J. A., Rotter, J. I., Rudan, I., Salomaa, V., Satterfield, S., Schadt, E. E., Schipf, S., Scott, L., Sehmi, J., Shen, J., Shin, C. S., Sigurdsson, G., Smith, S., Soranzo, N., Stancakova, A., Steinhagen-Thiessen, E., Streeten, E. A., Styrkarsdottir, U., Swart, K. M. A., Tan, S-T., Tarnopolsky, M. A., Thompson, P., Thomson, C. A., Thorsteinsdottir, U., Tikkanen, E., Tranah, G. J., Tuomilehto, J., van Schoor, N. M., Verma, A., Vollenweider, P., Voelzke, H., Wactawski-Wende, J., Walker, M., Weedon, M. N., Welch, R., Wichmann, H. -E., Widen, E., Williams, F. M. K., Wilson, J. F., Wright, N. C., Xie, W., Yu, L., Zhou, Y., Chambers, J. C., Doring, A., van Duijn, C. M., Econs, M. J., Gudnason, V., Kooner, J. S., Psaty, B. M., Spector, T. D., Stefansson, K., Rivadeneira, F., Uitterlinden, A. G., Wareham, N. J., Ossowski, V., Waterworth, D., Loos, R. J. F., Karasik, D., Harris, T. B., Ohlsson, C. & Kiel, D. P., 19 Jul 2017, In : Nature Communications. 8, 13 p., 80.

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Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer

Rodriguez-Broadbent, H., Law, P. J., Sud, A., Palin, K., Tuupanen, S., Gylfe, A., Hanninen, U. A., Cajuso, T., Tanskanen, T., Kondelin, J., Kaasinen, E., Sarin, A-P., Ripatti, S., Eriksson, J. G., Rissanen, H., Knekt, P., Pukkala, E., Jousilahti, P., Salomaa, V., Palotie, A. & 36 othersRenkonen-Sinisalo, L., Lepisto, A., Bohm, J., Mecklin, J-P., Al-Tassan, N. A., Palles, C., Martin, L., Barclay, E., Farrington, S. M., Timofeeva, M. N., Meyer, B. F., Wakil, S. M., Campbell, H., Smith, C. G., Idziaszczyk, S., Maughan, T. S., Kaplan, R., Kerr, R., Kerr, D., Passarelli, M. N., Figueiredo, J. C., Buchanan, D. D., Win, A. K., Hopper, J. L., Jenkins, M. A., Lindor, N. M., Newcomb, P. A., Gallinger, S., Conti, D., Schumacher, F., Casey, G., Aaltonen, L. A., Cheadle, J. P., Tomlinson, I. P., Dunlop, M. G. & Houlston, R. S., 15 Jun 2017, In : International Journal of Cancer. 140, 12, p. 2701-2708 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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Neuregulin signaling pathway in smoking behavior

Gupta, R., Qaiser, B., He, L., Hiekkalinna, T. S., Zheutlin, A. B., Therman, S., Ollikainen, M., Ripatti, S., Perola, M., Salomaa, V., Milani, L., Cannon, T. D., Madden, P. A. F., Korhonen, T., Kaprio, J. & Loukola, A., 22 Aug 2017, In : Translational Psychiatry. 7, 8 p., 1212.

Research output: Contribution to journalArticleScientificpeer-review

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Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

Wain, L. V., Vaez, A., Jansen, R., Joehanes, R., van der Most, P. J., Erzurumluoglu, A. M., O'Reilly, P. F., Cabrera, C. P., Warren, H. R., Rose, L. M., Verwoert, G. C., Hottenga, J-J., Strawbridge, R. J., Esko, T., Arking, D. E., Hwang, S-J., Guo, X., Kutalik, Z., Trompet, S., Shrine, N. & 33 othersTeumer, A., Ried, J. S., Bis, J. C., Smith, A. V., Amin, N., Nolte, I. M., Lyytikainen, L-P., Mahajan, A., Wareham, N. J., Hofer, E., Joshi, P. K., Kristiansson, K., Traglia, M., Havulinna, A. S., Goel, A., Nalls, M. A., Sober, S., Vuckovic, D., Luan, J., Del Greco M, F., Ayers, K. L., Marrugat, J., Ruggiero, D., Lopez, L. M., Niiranen, T., Enroth, S., Palotie, A., Ripatti, S., Sarin, A-P., Perola, M., BIOS Consortium, Lifelines Cohort Study & Understanding Soc Sci Grp, Sep 2017, In : Hypertension. 70, 3, p. E4-+ 49 p.

Research output: Contribution to journalArticleScientificpeer-review

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Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis

May-Wilson, S., Sud, A., Law, P. J., Palin, K., Tuupanen, S., Gylfe, A., Hänninen, U. A., Cajuso, T., Tanskanen, T., Kondelin, J., Kaasinen, E., Sarin, A-P., Eriksson, J. G., Rissanen, H., Knekt, P., Pukkala, E., Jousilahti, P., Salomaa, V., Ripatti, S., Palotie, A. & 34 othersRenkonen-Sinisalo, L., Lepisto, A., Böhm, J., Mecklin, J-P., Al-Tassan, N. A., Palles, C., Farrington, S. M., Timofeeva, M. N., Meyer, B. F., Wakil, S. M., Campbell, H., Smith, C. G., Idziaszczyk, S., Maughan, T. S., Fisher, D., Kerr, R., Kerr, D., Passarelli, M. N., Figueiredo, J. C., Buchanan, D. D., Win, A. K., Hopper, J. L., Jenkins, M. A., Lindor, N. M., Newcomb, P. A., Gallinger, S., Conti, D., Schumacher, F., Casey, G., Aaltonen, L. A., Cheadle, J. P., Tomlinson, I. P., Dunlop, M. G. & Houlston, R. S., Oct 2017, In : European Journal of Cancer. 84, p. 228-238 11 p.

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Prospects of Fine-Mapping Trait-Associated Genomic Regions by Using Summary Statistics from Genome-wide Association Studies

Benner, C., Havulinna, A. S., Järvelin, M-R., Salomaa, V., Ripatti, S. & Pirinen, M., 5 Oct 2017, In : American Journal of Human Genetics. 101, 4, p. 539-551 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Sepelvaltimotautiriskin arviointi genomitietoa hyödyntämällä

Widén, E. & Ripatti, S., 2017, In : Duodecim. 133, 8, p. 776-781 6 p.

Research output: Contribution to journalArticleProfessional

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Suomi luomassa genomiikan ja terveystiedon internetiä

Palotie, A. & Ripatti, S., 2017, In : Duodecim. 133, 8, p. 771-775 5 p.

Research output: Contribution to journalArticleProfessional

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