Research output per year
Research output per year
Personal profile
Fields of Science
- 3122 Cancers
International and National Collaboration
Publications and projects within past five years.
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A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells
Bulanova, D., Akimov, Y., Senkowski, W., Oikkonen, J., Gall-Mas, L., Timonen, S., Elmadani, M., Hynninen, J., Hautaniemi, S., Aittokallio, T. & Wennerberg, K., 23 May 2024, In: Science Advances. 10, 21, 15 p., eadj1564.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
Dual specific STAT3/5 degraders effectively block acute myeloid leukemia and natural killer/T cell lymphoma
Pölöske, D., Sorger, H., Schönbichler, A., de Araujo, E. D., Neubauer, H. A., Orlova, A., Timonen, S. H., Abdallah, D. I., Ianevski, A., Kuusanmäki, H., Surbek, M., Heyes, E., Eder, T., Wagner, C., Suske, T., Metzelder, M. L., Bergmann, M., Dahlhoff, M., Grebien, F. & Fleck, R. & 11 others, , Dec 2024, In: Hemasphere. 8, 12, 15 p., e70001.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Optimizing drug combinations for T-PLL: restoring DNA damage and P53-mediated apoptotic responses
von Jan, J., Timonen, S., Braun, T., Jiang, Q., Ianevski, A., Peng, Y., McConnell, K., Sindaco, P., Müller, T. A., Pützer, S., Klepzig, H., Jungherz, D., Dechow, A., Wahnschaffe, L., Giri, A. K., Kankainen, M., Kuusanmäki, H., Neubauer, H. A., Moriggl, R. & Mazzeo, P. & 12 others, , 10 Oct 2024, In: Blood. 144, 15, p. 1595–1610 16 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia
Toutah, K., Nawar, N., Timonen, S., Sorger, H., Raouf, Y. S., Bukhari, S., von Jan, J., Ianevski, A., Gawel, J. M., Olaoye, O. O., Geletu, M., Abdeldayem, A., Israelian, J., Radu, T. B., Sedighi, A., Bhatti, M. N., Hassan, M. M., Manaswiyoungkul, P., Shouksmith, A. E. & Neubauer, H. A. & 7 others, , 24 Jun 2021, In: Journal of Medicinal Chemistry. 64, 12, p. 8486-8509 24 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor
Jaiswal, A., Gautam, P., Pietilä, E. A., Timonen, S., Nordström, N., Akimov, Y., Sipari, N., Tanoli, Z., Fleischer, T., Lehti, K., Wennerberg, K. & Aittokallio, T., Mar 2021, In: Molecular Systems Biology. 17, 3, 25 p., 9526.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
Projects
- 1 Finished
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JAKSTAT TA: Uudet yksilölliset hoidot JAK/STAT vetoisissa T-solusyövissä
Aittokallio, T. (Project manager), Bentz, F. J. (Participant), He, L. (Participant), Ianevski, A. (Participant), Kumar, A. (Participant), Seref Vujaklija, C. (Participant) & Timonen, S. H. (Participant)
European Commission, Suomen Akatemia Projektilaskutus
01/01/2019 → 31/05/2023
Project: Research Council of Finland: Co-funded international programme