Photo of Sari Lauri
  • PL 56 (Viikinkaari 9)

    00014

    Finland

1993 …2020

Research output per year

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Personal profile

Description of research and teaching

https://www.helsinki.fi/en/researchgroups/synaptic-plasticity-and-development

 

My research group focuses on studying the molecular mechanisms guiding activity-dependent development of glutamatergic circuitry in the limbic system and in particular, the roles of ionotropic glutamate receptors in this process. So far, we have identified several novel features related to functions and regulation of AMPA and kainate-type glutamate receptors at the developing synapses. Our current research aims to understand in detail how these mechanisms contribute to development and fine-tuning of the neural circuits underlying behavior under physiological and aberrant conditions, such as early life stress.  

Our experimental approach involves the use of in vitro electrophysiological techniques in combination with pharmacological and local genetic manipulation in various neuronal preparations.

 

 

Fields of Science

  • 3112 Neurosciences

International and National Collaboration Publications and projects within past five years.

Publications

Kainate receptors regulate development of glutamatergic synaptic circuitry in the rodent amygdala

Ryazantseva, M., Englund, J., Shintyapina, A., Huupponen, J., Shteinikov, V., Pitkänen, A., Partanen, J. M. & Lauri, S. E., 23 Mar 2020, In : eLife. 9, 25 p., 52798.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

GluA4 Dependent Plasticity Mechanisms Contribute to Developmental Synchronization of the CA3-CA1 Circuitry in the Hippocampus

Atanasova, T., Kharybina, Z., Kaarela, T. A. M., Huupponen, J. T., Luchkina, N., Taira, T. P. & Lauri, S. E., Mar 2019, In : Neurochemical Research. 44, 3, p. 562–571 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

NETO1 Regulates Postsynaptic Kainate Receptors in CA3 Interneurons During Circuit Maturation

Orav, E., Dowavic, I., Huupponen, J., Taira, T. & Lauri, S., Nov 2019, In : Molecular Neurobiology. 56, 11, p. 7473-7489 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Plasma etched carbon microelectrode arrays for bioelectrical measurements

Heikkinen, J. J., Kaarela, T., Ludwig, A., Sukhanova, T., Khakipoor, S., Kim, S. I., Han, J. G., Huttunen, H. J., Rivera, C., Lauri, S. E., Taira, T., Jokinen, V. & Franssila, S., Nov 2018, In : Diamond and Related Materials. 90, p. 126-134 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Depolarizing γ-aminobutyric acid contributes to glutamatergic network rewiring in epilepsy

Kourdougli, N., Pellegrino, C., Renko, J-M., Khirug, S., Chazal, G., Kukko-Lukjanov, T-K., Lauri, S. E., Gaiarsa, J-L., Zhou, L., Peret, A., Castrén, E., Tuominen, R. K., Crepel, V. & Rivera Baeza, C., Feb 2017, In : Annals of Neurology. 81, 2, p. 251-265 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Activities

Nordic Neuroscience

Sari Lauri (Member of organizing committee)
12 Jun 201914 Jun 2019

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Pre-examination of doctoral dissertation: Meeri Mäkinen

Sari Lauri (Pre-examiner)
2018

Activity: Examination typesPre-examiner of doctoral thesis

Member of the thesis committee

Sari Lauri (Member of thesis committee / follow-up group)
2018 → …

Activity: Examination typesMember of doctoral thesis committee / follow-up group

Supervisor of doctoral thesis : Simo Ojanen

Sari Lauri (Supervisor)
2018 → …

Activity: Examination typesSupervisor or co-supervisor of doctoral thesis

11th FENS Forum of Neuroscience, Berlin 2018

Juzoh Umemori (Poster Presentation), Giuliano Didio (Attendee), Frederike Winkel (Attendee), Maria Llach Pou (Attendee), Chloé Buj (Attendee), Hanna Antila (Attendee), Ramon Guirado (Attendee), Sari Elina Lauri (Attendee), Tomi Petteri Taira (Attendee), Eero Castrén (Attendee)
7 Jul 201811 Jul 2018

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars