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Shiqian Li

  • PL 63 (Haartmaninkatu 8)

    00014

    Finland

20102020

Research output per year

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Publications

2020
Open Access

Membrane Curvature Catalyzes Lipid Droplet Assembly

Santinho, A., Salo, V. T., Chorlay, A., Li, S., Zhou, X., Omrane, M., Ikonen, E. & Thiam, A. R., 6 Jul 2020, In : Current Biology. 30, 13, p. 2481-+ 20 p.

Research output: Contribution to journalArticleScientificpeer-review

2019

An efficient auxin-inducible degron system with low basal degradation in human cells

Li, S., Prasanna, X., Salo, V. T., Vattulainen, I. & Ikonen, E., Sep 2019, In : Nature methods. 16, 9, p. 866-+ 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Seipin Facilitates Triglyceride Flow to Lipid Droplet and Counteracts Droplet Ripening via Endoplasmic Reticulum Contact

Salo, V. T., Li, S., Vihinen, H., Hölttä-Vuori, M., Szkalisity, A., Horvath, P., Belevich, I., Peränen, J., Thiele, C., Somerharju, P., Zhao, H., Santinho, A., Thiam, A. R., Jokitalo, E. & Ikonen, E., 19 Aug 2019, In : Developmental Cell. 50, 4, p. 478-+ 25 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2018

A Ceramide-Regulated Element in the Late Endosomal Protein LAPTM4B Controls Amino Acid Transporter Interaction

Zhou, K., Dichlberger, A., Martinez-Seara, H., Nyholm, T. K. M., Li, S., Kim, Y. A., Vattulainen, I., Ikonen, E. & Blom, T., 23 May 2018, In : ACS central science. 4, 5, p. 548-558 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells

Sandhu, J., Li, S., Fairall, L., Pfisterer, S. G., Gurnett, J. E., Xiao, X., Weston, T. A., Vashi, D., Ferrari, A., Orozco, J. L., Hartman, C. L., Strugatsky, D., Lee, S. D., He, C., Hong, C., Jiang, H., Bentolila, L. A., Gatta, A. T., Levine, T. P., Ferng, A. & 6 others, Lee, R., Ford, D. A., Young, S. G., Ikonen, E., Schwabe, J. W. R. & Tontonoz, P., 4 Oct 2018, In : Cell. 175, 2, p. 514-+ 36 p.

Research output: Contribution to journalArticleScientificpeer-review

OSBP-related protein-2 (ORP2): a novel Akt effector that controls cellular energy metabolism

Kentala, H., Koponen, A., Vihinen, H., Pirhonen, J., Liebisch, G., Pataj, Z., Kivelä, A., Li, S., Karhinen, L., Jääskeläinen, E., Andrews, R., Meriläinen, L., Matysik, S., Ikonen, E., Zhou, Y., Jokitalo, E. & Olkkonen, V. M., Nov 2018, In : Cellular and Molecular Life Sciences. 75, 21, p. 4041-4057 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2016

A loss-of-function variant in OSBPL1A predisposes to low plasma HDL cholesterol levels and impaired cholesterol efflux capacity

Motazacker, M. M., Pirhonen, J., van Capelleveen, J. C., Weber-Boyvat, M., Kuivenhoven, J. A., Shah, S., Hovingh, G. K., Metso, J., Li, S., Ikonen, E., Jauhiainen, M., Dallinga-Thie, G. M. & Olkkonen, V. M., Jun 2016, In : Atherosclerosis. 249, p. 140-147 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Seipin regulates ER-lipid droplet contacts and cargo delivery

Salo, V. T., Belevich, I., Li, S., Karhinen, L., Vihinen, H., Vigouroux, C., Magre, J., Thiele, C., Hölttä-Vuori, M., Jokitalo, E. & Ikonen, E., 2016, In : EMBO Journal. 35, 24, p. 2699-2716 18 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2015

Elevated Levels of StAR-Related Lipid Transfer Protein 3 Alter Cholesterol Balance and Adhesiveness of Breast Cancer Cells Potential Mechanisms Contributing to Progression of HER2-Positive Breast Cancers

Vassilev, B., Sihto, H., Li, S., Holtta-Vuori, M., Ilola, J., Lundin, J., Isola, J., Kellokumpu-Lehtinen, P-L., Joensuu, H. & Ikonen, E., Apr 2015, In : The American Journal of Pathology. 185, 4, p. 987-1000 14 p.

Research output: Contribution to journalArticleScientificpeer-review

LAPTM4B facilitates late endosomal ceramide export to control cell death pathways

Blom, T., Li, S., Dichlberger, A., Back, N., Kim, Y. A., Loizides-Mangold, U., Riezman, H., Bittman, R. & Ikonen, E., Oct 2015, In : Nature Chemical Biology. 11, 10, p. 799-+ 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Lipidienkuljettajaproteiinin metsästys johti syövän lääkeresistenssin jäljille

Blom, T., Li, S., Dichlberger, A., Back, N., Kim, Y. A., Loizides-Mangold, U., Riezman, H., Bittman, R. & Ikonen, E., 2015, In : Duodecim. 131, 20, p. 1900 1 p.

Research output: Contribution to journalArticleScientific

2013

LDL Cholesterol Recycles to the Plasma Membrane via a Rab8a-Myosin5b-Actin-Dependent Membrane Transport Route

Kanerva, K., Uronen, R-L., Blom, T., Li, S., Bittman, R., Lappalainen, P., Peränen, J., Raposo, G. & Ikonen, E., 11 Nov 2013, In : Developmental Cell. 27, 3, p. 249-262 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Oxysterol-binding proteins: Sterol and phosphoinositide sensors coordinating transport, signaling and metabolism

Olkkonen, V. M. & Li, S., Oct 2013, In : Progress in Lipid Research. 52, 4, p. 529-538 10 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

2011

OSBP-related protein 7 interacts with GATE-16 and negatively regulates GS28 protein stability

Zhou, W., Zhou, Y., Li, S., Zhou, T., Ma, H., Wei, K., Li, H., Olkkonen, V. & Yan, D., 6 Jun 2011, In : Experimental Cell Research. 317, p. 2353-2363 11 p.

Research output: Contribution to journalArticleScientificpeer-review

OSBP-Related Protein 8 (ORP8) Regulates Plasma and Liver Tissue Lipid Levels and Interacts with the Nucleoporin Nup62

Zhou, T., Li, S., Zhong, W., Vihervaara, T., Béaslas, O., Perttilä, J., Luo, W., Jiang, Y., Lehto, M., Olkkonen, V. & Yan, D., 15 Jun 2011, In : PLoS One. 6, e21078, p. 1-12 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2010

OSBP-related protein 11 (ORP11) dimerizes with ORP9 and localizes at the Golgi-late endosome interface

Zhou, Y., Li, S., Mäyränpää, M. I., Zhong, W., Bäck, N., Yan, D. & Olkkonen, V. M., 2010, In : Experimental Cell Research. 316, p. 3304-3316 13 p.

Research output: Contribution to journalArticleScientificpeer-review