No photo of Shishir Pant
  • PL 63 (Haartmaninkatu 8)

    00014

    Finland

20162019
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Personal profile

Fields of Science

  • 3111 Biomedicine

International and National Collaboration Publications and projects within past five years.

Publications 2016 2019

Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology

Damalanka, V. C., Han, Z., Karmakar, P., O'Donoghue, A. J., La Greca, F., Kim, T., Pant, S. M., Helander, J., Klefström, J., Craik, C. S. & Janetka, J. W., 24 Jan 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 480-490 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform

Pant, S. M., Mukonoweshuro, A., Desai, B., Ramjee, M. K., Selway, C. N., Tarver, G. J., Wright, A. G., Birchall, K., Chapman, T. M., Tervonen, T. A. & Klefström, J., 24 May 2018, In : Journal of Medicinal Chemistry. 61, 10, p. 4335-4347 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion

Tervonen, T. A., Belitskin, D., Pant, S. M., Englund, J. I., Marques, E., Ala-Hongisto, H., Nevalaita, L., Sihto, H., Heikkila, P., Leidenius, M., Hewitson, K., Ramachandra, M., Moilanen, A., Joensuu, H., Kovanen, P. E., Poso, A. & Klefstrom, J., 7 Apr 2016, In : Oncogene. 35, 14, p. 1832-1846 15 p.

Research output: Contribution to journalArticleScientificpeer-review