Research output per year
Research output per year
Personal profile
Curriculum vitae
Background and interests: Vascular biologist / genetic engineer. Interested in organ-specific characteristics blood and lymphatic vasculature in development and disease.
Keywords: Obesity; diabetes; blood and lymphatic vessels; inflammation; vascular leakage; intravital imaging; single-cell and bulk RNA sequencing.
See ORCID record for all (42) publications: https://orcid.org/0000-0002-0719-1773
Education information
B.Sc. Molecular Biology and Genetics, Istanbul Technical University, 2006
M.Sc. Molecular Biology-Genetics & Biotechnology, Istanbul Technical University, 2008
Dr. sc. ETH Zurich (Ph.D.) Swiss Federal Institute of Technology Zurich (ETH Zurich), 2012
Docent of Cell and Molecular Biology, Faculty of Medicine, University of Helsinki, 2018
Education/Academic qualification
Ph.D., Docent
External positions
Principal Investigator, Wihuri Reasearch Institute
1 Sep 2020 → …
Team Leader, Wihuri Research Institute
1 Feb 2018 → 31 Aug 2020
Fields of Science
- 3111 Biomedicine
- 1182 Biochemistry, cell and molecular biology
International and National Collaboration
Publications and projects within past five years.
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Blockade of VEGFR3 signaling leads to functional impairment of dural lymphatic vessels without affecting autoimmune neuroinflammation
Li, Z., Antila, S., Nurmi, H., Chilov, D., Korhonen, E. A., Fang, S., Karaman, S., Engelhardt, B. & Alitalo, K., 14 Apr 2023, In: Science immunology. 8, 82, 18 p., eabq0375.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
The angiopoietin receptor Tie2 is atheroprotective in arterial endothelium
Anisimov, A., Fang, S., Hemanthakumar, K. A., Örd, T., van Avondt, K., Chevre, R., Toropainen, A., Singha, P., Gilani, H., Nguyen, S. D., Karaman, S., Korhonen, E. A., Adams, R. H., Augustin, H. G., Öörni, K., Soehnlein, O., Kaikkonen, M. U. & Alitalo, K., 2023, In: Nature Cardiovascular Research. 2, 3, p. 307-321 15 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
A closer look at adipose tissue lymphatics and their markers
Lackman, M. H., Subashi, Y. & Karaman, S., May 2022, In: Current Opinion in Hematology. 29, 3, p. 144-150 7 p.Research output: Contribution to journal › Review Article › peer-review
Open AccessFile -
Interplay of vascular endothelial growth factor receptors in organ-specific vessel maintenance
Karaman, S., Paavonsalo, S., Heinolainen, K., Lackman, M. H., Ranta, A., Hemanthakumar, K. A., Kubota, Y. & Alitalo, K., 20 Jan 2022, In: Journal of Experimental Medicine. 219, 3, 25 p., 20210565.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
VEGF-C/VEGFR-3 signalling in macrophages ameliorates acute lung injury
Yamashita, M., Niisato, M., Kawasaki, Y., Karaman, S., Robciuc, M. R., Shibata, Y., Ishida, Y., Nishio, R., Masuda, T., Sugai, T., Ono, M., Tuder, R. M., Alitalo, K. & Yamauchi, K., 1 Apr 2022, In: European Respiratory Journal. 59, 4, 12 p., 2100880.Research output: Contribution to journal › Article › Scientific › peer-review
Projects
- 6 Active
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Adipose tissue endothelial cells in obesity: mechanisms of vessel dysfunction and capillary rarefaction
Karaman, S., Mäkelä, A., Paavonsalo, S. P. & Pakarinen, E.
Suomen Akatemia Projektilaskutus
01/09/2023 → 31/08/2025
Project: Academy of Finland: Academy Research Fellow's research expenses
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DIABETES FOUNDATION 2023 KARAMAN SINEM
01/07/2023 → 31/12/2024
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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WALDEMAR VON FRENCKELL 2023/LACKMAN MADE
Waldemar von Frenckells stiftelse c/o Nordea Private Banking
01/06/2023 → 29/02/2024
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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JUSELIUS 2023 KARAMAN SINEM
01/05/2023 → 31/12/2024
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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MAGNUS EHRNROOTH 04/2023-03/2024 KARAMAN
01/04/2023 → 31/03/2024
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
Prizes
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Academy Research Fellow: Research costs
Karaman, Sinem (Recipient), Sep 2020
Prize: Prizes and awards
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Early Career Researcher (Faculty of Medicine)
Karaman, Sinem (Recipient), Nov 2018
Prize: Prizes and awards
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Activities
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Emma Viittala's thesis supervisory board member
Sinem Karaman (Supervisor)
2023 → …Activity: Examination types › Member of doctoral thesis committee / follow-up group
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Invited talk at EnVI Lab (INSERMU1096) University of Rouen - Interplay of vascular endothelial growth factor receptors in organ-specific vessel maintenance
Sinem Karaman (Speaker)
7 Mar 2022Activity: Talk or presentation types › Invited talk
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Yujuan Xiang
Sinem Karaman (Host)
18 Jun 2022 → 28 Dec 2022Activity: Hosting a visitor types › Academic visit at UH
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Pre-examiner of Tiina Petäistö's doctoral thesis
Sinem Karaman (Supervisor)
11 Jul 2022 → 18 Aug 2022Activity: Examination types › Pre-examiner of doctoral thesis
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Invited talk at Bioinfocongress III – Vascular endothelial growth factor receptors in organ-specific vessel maintenance
Sinem Karaman (Speaker)
15 Oct 2022Activity: Talk or presentation types › Invited talk