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Sofia Helea Khan

20112023

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  • 2023

    PREDICT validity for prognosis of breast cancer patients with pathogenic BRCA1/2 variants

    Muranen, T. A., Morra, A., Khan, S. R., Barnes, D. K., Bolla, M., Dennis, J., Keeman, R., Leslie, G. T., Parsons, M., Wang, Q. U., Ahearn, T., Aittomäki, K., Andrulis, I. K., Arun, B., Behrens, S., Bialkowska, K. E., Bojesen, S. J., Camp, N., Chang-Claude, J., Czene, K., & 49 othersDevilee, P. M., Domchek, S. M., Dunning, A., Engel, C., Evans, D. G., Gago-Dominguez, M., Garcia-Closas, M., Gerdes, A-M., Glendon, G., Guenel, P., Hahnen, E., Hamann, U., Hanson, H. J., Hooning, M., Hoppe, R., Izatt, L., Jakubowska, A. A., James, P. N., Kristensen, V., Lalloo, F. J., Lindeman, G., Mannermaa, A., Margolin, S. L., Neuhausen, S. G., Newman, W., Peterlongo, P., Phillips, K-A., Pujana, M. A., Rantala, J., Ronlund, K., Saloustros, E. K., Schmutzler, R., Schneeweiss, A. F., Singer, C., Suvanto, M., Tan, Y. Y. R., Teixeira, M., Thomassen, M., Tischkowitz, M., Tripathi, V., Wappenschmidt, B., Zhao, E. F., Easton, D. C., Antoniou, A., Chenevix-Trench, G., Pharoah, P. D. P. K., Schmidt, M., Blomqvist, C. & Nevanlinna, H., 12 May 2023, In: Npj breast cancer. 9, 1, 15 p., 37.

    Research output: Contribution to journal › Article › Scientific › peer-review

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  • VarSCAT: A computational tool for sequence context annotations of genomic variants

    Wang, N., Khan, S. & Elo, L. L., Aug 2023, In: PLoS Computational Biology. 19, 8, 26 p., e1010727.

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  • 2021

    CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis

    Laine, A., Nagelli, S. G., Farrington, C., Butt, U., Cvrljevic, A. N., Vainonen, J. P., Feringa, F. M., Gronroos, T. J., Gautam, P., Khan, S., Sihto, H., Qiao, X., Pavic, K., Connolly, D. C., Kronqvist, P., Elo, L. L., Maurer, J., Wennerberg, K., Medema, R. H., Joensuu, H., & 4 othersPeuhu, E., de Visser, K., Narla, G. & Westermarck, J., Aug 2021, In: Cancer Research. 81, 16, p. 4319-4331 13 p.

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  • High mir-30 expression associates with improved breast cancer patient survival and treatment outcome

    Jamshidi, M., Fagerholm, R., Muranen, T. A., Kaur, S., Potdar, S., Khan, S., Netti, E., Mpindi, J-P., Yadav, B., Kiiski, J. I., Aittomäki, K., Heikkilä, P., Saarela, J., Bützow, R., Blomqvist, C. & Nevanlinna, H., Jun 2021, In: Cancers. 13, 12, 15 p., 2907.

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  • 2020

    Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer

    kConFab Investigators, HEBON Investigators, SWE BRCA Investigators, Muranen, T. A., Khan, S., Fagerholm, R., Aittomäki, K., Cunningham, J. M., Blomqvist, C. & Nevanlinna, H., 10 Sep 2020, In: Npj breast cancer. 6, 1, 13 p., 44.

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  • Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

    kConFab Investigators, ABCTB Investigators , EMBRACE Study, GEMO Study Collaborators, Zhan, H., Ahearn, T. U., Lecarpentier, J., Aittomäki, K., Blomqvist, C., Khan, S., Muranen, T. A. & Nevanlinna, H., Jun 2020, In: Nature Genetics. 52, 6, p. 572-+ 19 p.

    Research output: Contribution to journal › Article › Scientific › peer-review

  • SNPs in lncRNA regions and breast cancer risk

    Suvanto, M., Beesley, J., Blomqvist, C., Chenevix-Trench, G., Khan, S. & Nevanlinna, H., 2020, In: Frontiers in Genetics. 11, 16 p., 550.

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  • 2019

    Genome-wide association study of germline variants and breast cancer-specific mortality

    NBCS Collaborators, Escala-Garcia, M., Guo, Q., Doerk, T., Blomqvist, C., Khan, S., Kiiski, J. I. & Nevanlinna, H., 19 Mar 2019, In: British Journal of Cancer. 120, 6, p. 647-657 11 p.

    Research output: Contribution to journal › Article › Scientific › peer-review

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  • 2018

    Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling

    Andersson, E. I., Pützer, S., Yadav, B., Dufva, O., Khan, S., He, L., Sellner, L., Schrader, A., Crispatzu, G., Oleś, M., Zhang, H., Adnan-Awad, S., Lagström, S., Bellanger, D., Mpindi, J. P., Eldfors, S., Pemovska, T., Pietarinen, P., Lauhio, A., Tomska, K., & 19 othersCuesta-Mateos, C., Faber, E., Koschmieder, S., Brümmendorf, T. H., Kytölä, S., Savolainen, E-R., Siitonen, T., Ellonen, P., Kallioniemi, O., Wennerberg, K., Ding, W., Stern, M-H., Huber, W., Anders, S., Tang, J., Aittokallio, T., Zenz, T., Herling, M. & Mustjoki, S., Mar 2018, In: Leukemia. 32, 3, p. 774-787 14 p.

    Research output: Contribution to journal › Article › Scientific › peer-review

  • Meta-analysis of three genome-wide association studies identifies two loci that predict survival and treatment outcome in breast cancer

    Khan, S., Fagerholm, R., Kadalayil, L., Tapper, W., Aittomäki, K., Liu, J., Blomqvist, C., Eccles, D. & Nevanlinna, H., 9 Jan 2018, In: Oncotarget. 9, 3, p. 4249-4257 9 p.

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  • 2017

    Association analysis identifies 65 new breast cancer risk loci

    Michailidou, K., Lindstrom, S., Dennis, J., Beesley, J., Hui, S., Kar, S., Lemacon, A., Soucy, P., Glubb, D., Rostamianfar, A., Bolla, M. K., Wang, Q., Tyrer, J., Dicks, E., Lee, A., Wang, Z., Allen, J., Keeman, R., Eilber, U., French, J. D., & 33 othersChen, X. Q., Fachal, L., McCue, K., McCart, A. E., Reed, A. E. M., Ghoussaini, M., Carroll, J. S., Jiang, X., Finucane, H., Adams, M., Adank, M. A., Ahsan, H., Aittomaki, K., Anton-Culver, H., Antonenkova, N. N., Arndt, V., Aronson, K. J., Arun, B., Auer, P. L., Bacot, F., Barrdahl, M., Baynes, C., Beckmann, M. W., Behrens, S., Benitez, J., Bermisheva, M., Blomqvist, C., Khan, S., Kiiski, J. I., Nevanlinna, H., NBCS Collaborators, ABCTB Investigators & kConFab-AOCS Investigators, 2 Nov 2017, In: Nature. 551, 7678, p. 92-+ 24 p.

    Research output: Contribution to journal › Article › Scientific › peer-review

  • FANCM mutation c.5791C > T is a risk factor for triple-negative breast cancer in the Finnish population

    Kiiski, J. I., Tervasmäki, A., Pelttari, L. M., Khan, S., Mantere, T., Pylkäs, K., Mannermaa, A., Tengström, M., Kvist, A., Borg, Å., Kosma, V-M., Kallioniemi, A., Schleutker, J., Bützow, R., Blomqvist, C., Aittomäki, K., Winqvist, R. & Nevanlinna, H., Nov 2017, In: Breast Cancer Research and Treatment. 166, 1, p. 217-226 10 p.

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  • Genetic modifiers of CHEK2*1100delC-associated breast cancer risk

    Muranen, T. A., Greco, D., Blomqvist, C., Aittomäki, K., Khan, S., Hogervorst, F., Verhoef, S., Pharoah, P. D. P., Dunning, A. M., Shah, M., Luben, R., Bojesen, S. E., Nordestgaard, B. G., Schoemaker, M., Swerdlow, A., Garcia-Closas, M., Figueroa, J., Doerk, T., Bogdanova, N. V., Hall, P., & 33 othersLi, J., Khusnutdinova, E., Bermisheva, M., Kristensen, V., Borresen-Dale, A-L., Peto, J., Silva, I. D. S., Couch, F. J., Olson, J. E., Hillemans, P., Park-Simon, T-W., Brauch, H., Hamann, U., Burwinkel, B., Marme, F., Meindl, A., Schmutzler, R. K., Cox, A., Cross, S. S., Sawyer, E. J., Tomlinson, I., Lambrechts, D., Moisse, M., Lindblom, A., Margolin, S., Hollestelle, A., Martens, J. W. M., Fasching, P. A., Beckmann, M. W., Nevanlinna, H., NBCS Investigators, kConFab-AOCS Investigators & Breast Canc Assoc Consortium, May 2017, In: Genetics In medicine. 19, 5, p. 599-603 5 p.

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  • Germline variation in ADAMTSL1 is associated with prognosis following breast cancer treatment in young women

    Kadalayil, L., Khan, S., Nevanlinna, H., Fasching, P. A., Couch, F. J., Hopper, J. L., Liu, J., Maishman, T., Durcan, L., Gerty, S., Blomqvist, C., Rack, B., Janni, W., Collins, A., Eccles, D. & Tapper, W., 21 Nov 2017, In: Nature Communications. 8, 12 p., 1632.

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  • Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores

    Lecarpentier, J., Silvestri, V., Kuchenbaecker, K. B., Barrowdale, D., Dennis, J., McGuffog, L., Soucy, P., Leslie, G., Rizzolo, P., Navazio, A. S., Valentini, V., Zelli, V., Lee, A., Al Olama, A. A., Tyrer, J. P., Southey, M., John, E. M., Conner, T. A., Goldgar, D. E., Buys, S. S., & 34 othersJanavicius, R., Steele, L., Ding, Y. C., Neuhausen, S. L., Hansen, T. V. O., Osorio, A., Weitzel, J. N., Toss, A., Medici, V., Cortesi, L., Zanna, I., Palli, D., Radice, P., Manoukian, S., Peissel, B., Azzollini, J., Viel, A., Cini, G., Damante, G., Tommasi, S., Peterlongo, P., Fostira, F., Hamann, U., Evans, D. G., Henderson, A., Brewer, C., Kiiski, J. I., Aittomäki, K., Khan, S., Nevanlinna, H., EMBRACE, GEMO Study Collaborators, HEBON & kConFab Investigators, 10 Jul 2017, In: Journal of Clinical Oncology. 35, 20, p. 2240-+ 17 p.

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  • TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer

    Fagerholm, R., Khan, S., Schmidt, M. K., Garcia-Closas, M., Heikkilä, P., Saarela, J., Beesley, J., Jamshidi, M., Aittomäki, K., Liu, J., Ali, H. R., Andrulis, I. L., Beckmann, M. W., Behrens, S., Blows, F. M., Brenner, H., Chang-Claude, J., Couch, F. J., Czene, K., Fasching, P. A., & 31 othersFigueroa, J., Floris, G., Glendon, G., Guo, Q., Hall, P., Hallberg, E., Hamann, U., Holleczek, B., Hooning, M. J., Hopper, J. L., Jager, A., Kabisch, M., Keeman, R., Kosma, V-M., Lambrechts, D., Lindblom, A., Mannermaa, A., Margolin, S., Provenzano, E., Shah, M., Southey, M. C., Dennis, J., Lush, M., Michailidou, K., Wang, Q., Bolla, M. K., Dunning, A. M., Easton, D. F., Blomqvist, C., Nevanlinna, H. & kConFab-AOCS Investigators, 2017, In: Oncotarget. 8, 11, p. 18381-18398 18 p.

    Research output: Contribution to journal › Article › Scientific › peer-review

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  • 2016

    An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression

    Wyszynski, A., Hong, C-C., Lam, K., Michailidou, K., Lytle, C., Yao, S., Zhang, Y., Bolla, M. K., Wang, Q., Dennis, J., Hopper, J. L., Southey, M. C., Schmidt, M. K., Broeks, A., Muir, K., Lophatananon, A., Fasching, P. A., Beckmann, M. W., Peto, J., dos-Santos-Silva, I., & 33 othersSawyer, E. J., Tomlinson, I., Burwinkel, B., Marme, F., Guenel, P., Truong, T., Bojesen, S. E., Nordestgaard, B. G., Gonzalez-Neira, A., Benitez, J., Neuhausen, S. L., Brenner, H., Dieffenbach, A. K., Meindl, A., Schmutzler, R. K., Brauch, H., Nevanlinna, H., Khan, S., Matsuo, K., Ito, H., Doerk, T., Bogdanova, N. V., Lindblom, A., Margolin, S., Mannermaa, A., Kosma, V-M., Wu, A. H., Van den Berg, D., Lambrechts, D., Wildiers, H., GENICA Network , kConFab Investigators & Australian Ovarian Canc Study Grp , 1 Sep 2016, In: Human Molecular Genetics. 25, 17, p. 3863-3876 14 p.

    Research output: Contribution to journal › Article › Scientific › peer-review

  • Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry

    Zhao, Z., Wen, W., Michailidou, K., Bolla, M. K., Wang, Q., Zhang, B., Long, J., Shu, X-O., Schmidt, M. K., Milne, R. L., Garcia-Closas, M., Chang-Claude, J., Lindstrom, S., Bojesen, S. E., Ahsan, H., Aittomäki, K., Andrulis, I. L., Anton-Culver, H., Arndt, V., Beckmann, M. W., & 98 othersBeeghly-Fadiel, A., Benitez, J., Blomqvist, C., Bogdanova, N. V., Borresen-Dale, A-L., Brand, J., Brauch, H., Brenner, H., Burwinkel, B., Cai, Q., Casey, G., Chenevix-Trench, G., Couch, F. J., Cox, A., Cross, S. S., Czene, K., Doerk, T., Dumont, M., Fasching, P. A., Figueroa, J., Flesch-Janys, D., Fletcher, O., Flyger, H., Fostira, F., Gammon, M., Giles, G. G., Guenel, P., Haiman, C. A., Hamann, U., Harrington, P., Hartman, M., Hooning, M. J., Hopper, J. L., Jakubowska, A., Jasmine, F., John, E. M., Johnson, N., Kabisch, M., Khan, S., Kibriya, M., Knight, J. A., Kosma, V-M., Kriege, M., Kristensen, V., Le Marchand, L., Lee, E., Li, J., Lindblom, A., Lophatananon, A., Luben, R., Lubinski, J., Malone, K. E., Mannermaa, A., Manoukian, S., Margolin, S., Marme, F., McLean, C., Meijers-Heijboer, H., Meindl, A., Miao, H., Muir, K., Neuhausen, S. L., Nevanlinna, H., Neven, P., Olson, J. E., Perkins, B., Peterlongo, P., Phillips, K-A., Pylkas, K., Rudolph, A., Santella, R., Sawyer, E. J., Schmutzler, R. K., Schoemaker, M., Shah, M., Shrubsole, M., Southey, M. C., Swerdlow, A. J., Toland, A. E., Tomlinson, I., Torres, D., Therese, T., Ursin, G., Van Der Luijt, R. B., Verhoef, S., Wang-Gohrke, S., Whittemore, A. S., Winqvist, R., Zamora, M. P., Zhao, H., Dunning, A. M., Simard, J., Hall, P., Kraft, P., Pharoah, P., Hunter, D., Easton, D. F. & Zheng, W., May 2016, In: Cancer Causes & Control. 27, 5, p. 679-693 15 p.

    Research output: Contribution to journal › Article › Scientific › peer-review

  • BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

    Meeks, H. D., Song, H., Michailidou, K., Bolla, M. K., Dennis, J., Wang, Q., Barrowdale, D., Frost, D., McGuffog, L., Ellis, S., Feng, B., Buys, S. S., Hopper, J. L., Southey, M. C., Tesoriero, A., James, P. A., Bruinsma, F., Campbell, I. G., Broeks, A., Schmidt, M. K., & 37 othersHogervorst, F. B. L., Beckman, M. W., Fasching, P. A., Fletcher, O., Johnson, N., Sawyer, E. J., Riboli, E., Banerjee, S., Menon, U., Tomlinson, I., Burwinkel, B., Hamann, U., Marme, F., Rudolph, A., Janavicius, R., Tihomirova, L., Tung, N., Garber, J., Cramer, D., Terry, K. L., Poole, E. M., Tworoger, S. S., Dorfling, C. M., van Rensburg, E. J., Blomqvist, C., Khan, S., Nevanlinna, H., Pelttari, L. M., Aittomäki, K., Butzow, R., EMBRACE, kConFab Investigators, Australia Ovarian Canc Study Grp, HEBON, GEMO Study Collaborators, OCGN & PRostate Canc Assoc Grp, Feb 2016, In: Journal of the National Cancer Institute. 108, 2, 10 p., 315.

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    Open Access

  • Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170

    Dunning, A. M., Michailidou, K., Kuchenbaecker, K. B., Thompson, D., French, J. D., Beesley, J., Healey, C. S., Kar, S., Pooley, K. A., Lopez-Knowles, E., Dicks, E., Barrowdale, D., Sinnott-Armstrong, N. A., Sallari, R. C., Hillman, K. M., Kaufmann, S., Sivakumaran, H., Marjaneh, M. M., Lee, J. S., Hills, M., & 228 othersJarosz, M., Drury, S., Canisius, S., Bolla, M. K., Dennis, J., Wang, Q., Hopper, J. L., Southey, M. C., Broeks, A., Schmidt, M. K., Lophatananon, A., Muir, K., Beckmann, M. W., Fasching, P. A., dos-Santos-Silva, I., Peto, J., Sawyer, E. J., Tomlinson, I., Burwinkel, B., Marme, F., Guenel, P., Truong, T., Bojesen, S. E., Flyger, H., Gonzalez-Neira, A., Perez, J. I. A., Anton-Culver, H., Eunjung, L., Arndt, V., Brenner, H., Meindl, A., Schmutzler, R. K., Brauch, H., Hamann, U., Aittomäki, K., Blomqvist, C., Ito, H., Matsuo, K., Bogdanova, N., Dork, T., Lindblom, A., Margolin, S., Kosma, V-M., Mannermaa, A., Tseng, C., Wu, A. H., Lambrechts, D., Wildiers, H., Chang-Claude, J., Rudolph, A., Peterlongo, P., Radice, P., Olson, J. E., Giles, G. G., Milne, R. L., Haiman, C. A., Henderson, B. E., Goldberg, M. S., Teo, S. H., Yip, C. H., Nord, S., Borresen-Dale, A-L., Kristensen, V., Long, J., Zheng, W., Pylkas, K., Winqvist, R., Andrulis, I. L., Knight, J. A., Devilee, P., Seynaeve, C., Figueroa, J., Sherman, M. E., Czene, K., Darabi, H., Hollestelle, A., van den Ouweland, A. M. W., Humphreys, K., Gao, Y-T., Shu, X-O., Cox, A., Cross, S. S., Blot, W., Cai, Q., Ghoussaini, M., Perkins, B. J., Shah, M., Choi, J-Y., Kang, D., Lee, S. C., Hartman, M., Kabisch, M., Torres, D., Jakubowska, A., Lubinski, J., Brennan, P., Sangrajrang, S., Ambrosone, C. B., Toland, A. E., Shen, C-Y., Wu, P-E., Orr, N., Swerdlow, A., McGuffog, L., Healey, S., Lee, A., Kapuscinski, M., John, E. M., Terry, M. B., Daly, M. B., Goldgar, D. E., Buys, S. S., Janavicius, R., Tihomirova, L., Tung, N., Dorfling, C. M., van Rensburg, E. J., Neuhausen, S. L., Ejlertsen, B., Hansen, T. V. O., Osorio, A., Benitez, J., Rando, R., Weitzel, J. N., Bonanni, B., Peissel, B., Manoukian, S., Papi, L., Ottini, L., Konstantopoulou, I., Apostolou, P., Garber, J., Rashid, M. U., Frost, D., Izatt, L., Ellis, S., Godwin, A. K., Arnold, N., Niederacher, D., Rhiem, K., Bogdanova-Markov, N., Sagne, C., Stoppa-Lyonnet, D., Damiola, F., Sinilnikova, O. M., Mazoyer, S., Isaacs, C., Claes, K. B. M., De Leeneer, K., De la Hoya, M., Caldes, T., Nevanlinna, H., Khan, S., Mensenkamp, A. R., Hooning, M. J., Rookus, M. A., Kwong, A., Olah, E., Diez, O., Brunet, J., Pujana, M. A., Gronwald, J., Huzarski, T., Barkardottir, R. B., Laframboise, R., Soucy, P., Montagna, M., Agata, S., Teixeira, M. R., Park, S. K., Lindor, N., Couch, F. J., Tischkowitz, M., Foretova, L., Vijai, J., Offit, K., Singer, C. F., Rappaport, C., Phelan, C. M., Greene, M. H., Mai, P. L., Rennert, G., Imyanitov, E. N., Hulick, P. J., Phillips, K-A., Piedmonte, M., Mulligan, A. M., Glendon, G., Bojesen, A., Thomassen, M., Caligo, M. A., Yoon, S-Y., Friedman, E., Laitman, Y., Borg, A., Von Wachenfeldt, A., Ehrencrona, H., Rantala, J., Olopade, O. I., Ganz, P. A., Nussbaum, R. L., Gayther, S. A., Nathanson, K. L., Domchek, S. M., Arun, B. K., Mitchell, G., Karlan, B. Y., Lester, J., Maskarinec, G., Woolcott, C., Scott, C., Stone, J., Apicella, C., Tamimi, R., Luben, R., Khaw, K-T., Helland, A., Haakensen, V., Dowsett, M., Pharoah, P. D. P., Simard, J., Hall, P., Garcia-Closas, M., Vachon, C., Chenevix-Trench, G., Antoniou, A. C., Easton, D. F. & Edwards, S. L., Apr 2016, In: Nature Genetics. 48, 4, p. 374-+ 16 p.

    Research output: Contribution to journal › Article › Scientific › peer-review

  • Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation

    Ghoussaini, M., French, J. D., Michailidou, K., Nord, S., Beesley, J., Canisus, S., Hillman, K. M., Kaufmann, S., Sivakumaran, H., Marjaneh, M. M., Lee, J. S., Dennis, J., Bolla, M. K., Wang, Q., Dicks, E., Milne, R. L., Hopper, J. L., Southey, M. C., Schmidt, M. K., Broeks, A., & 32 othersMuir, K., Lophatananon, A., Fasching, P. A., Beckmann, M. W., Fletcher, O., Johnson, N., Sawyer, E. J., Tomlinson, I., Burwinkel, B., Marme, F., Guenel, P., Truong, T., Bojesen, S. E., Flyger, H., Benitez, J., Gonzalez-Neira, A., Alonso, R., Pita, G., Neuhausen, S. L., Anton-Culver, H., Brenner, H., Arndt, V., Meindl, A., Schmutzler, R. K., Brauch, H., Hamann, U., Tessier, D. C., Vincent, D., Nevanlinna, H., Khan, S., kConFab AOCS & NBCS Collaborators, 6 Oct 2016, In: American Journal of Human Genetics. 99, 4, p. 903-911 9 p.

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  • FANCM c.5101C > T mutation associates with breast cancer survival and treatment outcome

    Kiiski, J., Fagerholm, R., Tervasmaki, A., Pelttari, L. M., Khan, S., Jamshidi, M., Mantere, T., Pylkas, K., Bartek, J., Bartkova, J., Mannermaa, A., Tengstrom, M., Kosma, V-M., Winqvist, R., Kallioniemi, A., Aittomäki, K., Blomqvist, C. & Nevanlinna, H., Dec 2016, In: International Journal of Cancer. 139, 12, p. 2760-2770 11 p.

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  • Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus

    Horne, H. N., Chung, C. C., Zhang, H., Yu, K., Prokunina-Olsson, L., Michailidou, K., Bolla, M. K., Wang, Q., Dennis, J., Hopper, J. L., Southey, M. C., Schmidt, M. K., Broeks, A., Muir, K., Lophatananon, A., Fasching, P. A., Beckmann, M. W., Fletcher, O., Johnson, N., Sawyer, E. J., & 31 othersTomlinson, I., Burwinkel, B., Marme, F., Guenel, P., Truong, T., Bojesen, S. E., Flyger, H., Benitez, J., Gonzalez-Neira, A., Anton-Culver, H., Neuhausen, S. L., Brenner, H., Arndt, V., Meindl, A., Schmutzler, R. K., Brauch, H., Hamann, U., Nevanlinna, H., Khan, S., Matsuo, K., Iwata, H., Dork, T., Bogdanova, N. V., Lindblom, A., Margolin, S., Mannermaa, A., Kosma, V-M., Chenevix-Trench, G., Wu, A. H., den Berg, D. V. & kConFab-AOCS Investigators, 24 Aug 2016, In: PLoS One. 11, 8, 15 p., 0160316.

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  • Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

    kConFab Investigators, 2016, In: PLoS One. 11, 7, 19 p., 0158801.

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  • Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer

    Shi, J., Zhang, Y., Zheng, W., Michailidou, K., Ghoussaini, M., Bolla, M. K., Khan, S., Nevanlinna, H. A. & Long, J., 2016, In: International Journal of Cancer. 139, 6, p. 1303-1317 15 p.

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  • Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs)

    Darabi, H., Beesley, J., Droit, A., Kar, S., Nord, S., Marjaneh, M. M., Soucy, P., Michailidou, K., Ghoussaini, M., Wahl, H. F., Bolla, M. K., Wang, Q., Dennis, J., Alonso, M. R., Andrulis, I. L., Anton-Culver, H., Arndt, V., Beckmann, M. W., Benitez, J., Bogdanova, N. V., & 94 othersBojesen, S. E., Brauch, H., Brenner, H., Broeks, A., Bruening, T., Burwinkel, B., Chang-Claude, J., Choi, J-Y., Conroy, D. M., Couch, F. J., Cox, A., Cross, S. S., Czene, K., Devilee, P., Doerk, T., Easton, D. F., Fasching, P. A., Figueroa, J., Fletcher, O., Flyger, H., Galle, E., Garcia-Closas, M., Giles, G. G., Goldberg, M. S., Gonzalez-Neira, A., Guenel, P., Haiman, C. A., Hallberg, E., Hamann, U., Hartman, M., Hollestelle, A., Hopper, J. L., Ito, H., Jakubowska, A., Johnson, N., Kang, D., Khan, S., Kosma, V-M., Kriege, M., Kristensen, V., Lambrechts, D., Le Marchand, L., Lee, S. C., Lindblom, A., Lophatananon, A., Lubinski, J., Mannermaa, A., Manoukian, S., Margolin, S., Matsuo, K., Mayes, R., Mckay, J., Meindl, A., Milne, R. L., Muir, K., Neuhausen, S. L., Nevanlinna, H., Olswold, C., Orr, N., Peterlongo, P., Pita, G., Pylkaes, K., Rudolph, A., Sangrajrang, S., Sawyer, E. J., Schmidt, M. K., Schmutzler, R. K., Seynaeve, C., Shah, M., Shen, C-Y., Shu, X-O., Southey, M. C., Stram, D. O., Surowy, H., Swerdlow, A., Teo, S. H., Tessier, D. C., Tomlinson, I., Torres, D., Truong, T., Vachon, C. M., Vincent, D., Winqvist, R., Wu, A. H., Wu, P-E., Yip, C. H., Zheng, W., Pharoah, P. D. P., Hall, P., Edwards, S. L., Simard, J., French, J. D., Chenevix-Trench, G. & Dunning, A. M., 7 Sep 2016, In: Scientific Reports. 6, 14 p., 32512.

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  • Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

    Lawrenson, K., Kar, S., McCue, K., Kuchenbaeker, K., Michailidou, K., Tyrer, J., Beesley, J., Ramus, S. J., Li, Q., Delgado, M. K., Lee, J. M., Aittomäki, K., Andrulis, I. L., Anton-Culver, H., Arndt, V., Arun, B. K., Arver, B., Bandera, E. V., Barile, M., Barkardottir, R. B., & 35 othersBarrowdale, D., Beckmann, M. W., Benitez, J., Berchuck, A., Bisogna, M., Bjorge, L., Blomqvist, C., Blot, W., Bogdanova, N., Bojesen, A., Bojesen, S. E., Bolla, M. K., Bonanni, B., Borresen-Dale, A-L., Brauch, H., Brennan, P., Brenner, H., Bruinsma, F., Brunet, J., Buhari, S. A., Burwinkel, B., Butzow, R., Buys, S. S., Cai, Q., Caldes, T., Campbell, I., Canniotto, R., Chang-Claude, J., Khan, S., Nevanlinna, H., GEMO Study Collaborators, EMBRACE, Hereditary Breast & Ovarian Canc R, kConFab Investigators & Australian Ovarian Canc Study Grp , Sep 2016, In: Nature Communications. 7, 22 p., 12675.

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  • Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

    Couch, F. J., Kuchenbaecker, K. B., Michailidou, K., Mendoza-Fandino, G. A., Nord, S., Lilyquist, J., Olswold, C., Hallberg, E., Agata, S., Ahsan, H., Aittomäki, K., Ambrosone, C., Andrulis, I. L., Anton-Culver, H., Arndt, V., Arun, B. K., Arver, B., Barile, M., Barkardottir, R. B., Barrowdale, D., & 229 othersBeckmann, L., Beckmann, M. W., Benitez, J., Blank, S. V., Blomqvist, C., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Bonanni, B., Brauch, H., Brenner, H., Burwinkel, B., Buys, S. S., Caldes, T., Caligo, M. A., Canzian, F., Carpenter, J., Chang-Claude, J., Chanock, S. J., Chung, W. K., Claes, K. B. M., Cox, A., Cross, S. S., Cunningham, J. M., Czene, K., Daly, M. B., Damiola, F., Darabi, H., de la Hoya, M., Devilee, P., Diez, O., Ding, Y. C., Dolcetti, R., Domchek, S. M., Dorfling, C. M., dos-Santos-Silva, I., Dumont, M., Dunning, A. M., Eccles, D. M., Ehrencrona, H., Ekici, A. B., Eliassen, H., Ellis, S., Fasching, P. A., Figueroa, J., Flesch-Janys, D., Foersti, A., Fostira, F., Foulkes, W. D., Friebel, T., Friedman, E., Frost, D., Gabrielson, M., Gammon, M. D., Ganz, P. A., Gapstur, S. M., Garber, J., Gaudet, M. M., Gayther, S. A., Gerdes, A-M., Ghoussaini, M., Giles, G. G., Glendon, G., Godwin, A. K., Goldberg, M. S., Goldgar, D. E., Gonzalez-Neira, A., Greene, M. H., Gronwald, J., Guenel, P., Gunter, M., Haeberle, L., Haiman, C. A., Hamann, U., Hansen, T. V. O., Hart, S., Healey, S., Heikkinen, T., Henderson, B. E., Herzog, J., Hogervorst, F. B. L., Hollestelle, A., Hooning, M. J., Hoover, R. N., Hopper, J. L., Humphreys, K., Hunter, D. J., Huzarski, T., Imyanitov, E. N., Isaacs, C., Jakubowska, A., James, P., Janavicius, R., Jensen, U. B., John, E. M., Jones, M., Kabisch, M., Kar, S., Karlan, B. Y., Khan, S., Khaw, K-T., Kibriya, M. G., Knight, J. A., Ko, Y-D., Konstantopoulou, I., Kosma, V-M., Kristensen, V., Kwong, A., Laitman, Y., Lambrechts, D., Lazaro, C., Lee, E., Le Marchand, L., Lester, J., Lindblom, A., Lindor, N., Lindstrom, S., Liu, J., Long, J., Lubinski, J., Mai, P. L., Makalic, E., Malone, K. E., Mannermaa, A., Manoukian, S., Margolin, S., Marme, F., Martens, J. W. M., McGuffog, L., Meindl, A., Miller, A., Milne, R. L., Miron, P., Montagna, M., Mazoyer, S., Mulligan, A. M., Muranen, T. A., Nathanson, K. L., Neuhausen, S. L., Nevanlinna, H., Nordestgaard, B. G., Nussbaum, R. L., Offit, K., Olah, E., Olopade, O. I., Olson, J. E., Osorio, A., Park, S. K., Peeters, P. H., Peissel, B., Peterlongo, P., Peto, J., Phelan, C. M., Pilarski, R., Poppe, B., Pylkaes, K., Radice, P., Rahman, N., Rantala, J., Rappaport, C., Rennert, G., Richardson, A., Robson, M., Romieu, I., Rudolph, A., Rutgers, E. J., Sanchez, M-J., Santella, R. M., Sawyer, E. J., Schmidt, D. F., Schmidt, M. K., Schmutzler, R. K., Schumacher, F., Scott, R., Senter, L., Sharma, P., Simard, J., Singer, C. F., Sinilnikova, O. M., Soucy, P., Southey, M., Steinemann, D., Stenmark-Askmalm, M., Stoppa-Lyonnet, D., Swerdlow, A., Szabo, C. I., Tamimi, R., Tapper, W., Teixeira, M. R., Teo, S-H., Terry, M. B., Thomassen, M., Thompson, D., Tihomirova, L., Toland, A. E., Tollenaar, R. A. E. M., Tomlinson, I., Truong, T., Tsimiklis, H., Teule, A., Tumino, R., Tung, N., Turnbull, C., Ursin, G., van Deurzen, C. H. M., van Rensburg, E. J., Varon-Mateeva, R., Wang, Z., Wang-Gohrke, S., Weiderpass, E., Weitzel, J. N., Whittemore, A., Wildiers, H., Winqvist, R., Yang, X. R., Yannoukakos, D., Yao, S., Zamora, M. P., Zheng, W., Hall, P., Kraft, P., Vachon, C., Slager, S., Chenevix-Trench, G., Pharoah, P. D. P., Monteiro, A. A. N., Garcia-Closas, M., Easton, D. F. & Antoniou, A. C., Apr 2016, In: Nature Communications. 7, 13 p., 11375.

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  • Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus

    Zeng, C., Guo, X., Long, J., Kuchenbaecker, K. B., Droit, A., Michailidou, K., Ghoussaini, M., Kar, S., Freeman, A., Hopper, J. L., Milne, R. L., Bolla, M. K., Wang, Q., Dennis, J., Agata, S., Ahmed, S., Aittomäki, K., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., & 35 othersArason, A., Arndt, V., Arun, B. K., Arver, B., Bacot, F., Barrowdale, D., Baynes, C., Beeghly-Fadiel, A., Benitez, J., Bermisheva, M., Blomqvist, C., Blot, W. J., Bogdanova, N. V., Bojesen, S. E., Bonanni, B., Borresen-Dale, A-L., Brand, J. S., Brauch, H., Brennan, P., Brenner, H., Broeks, A., Bruening, T., Burwinkel, B., Buys, S. S., Cai, Q., Caldes, T., Campbell, I., Carpenter, J., Khan, S., Nevanlinna, H., EMBRACE, GEMO Study Collaborators, HEBON, KConFab & AOCS Investigators, 21 Jun 2016, In: Breast Cancer Research. 18, 21 p., 64.

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  • Polygenic risk score is associated with increased disease risk in 52 Finnish breast cancer families

    Muranen, T. A., Mavaddat, N., Khan, S., Fagerholm, R., Pelttari, L., Lee, A., Aittomäki, K., Blomqvist, C., Easton, D. F. & Nevanlinna, H., Aug 2016, In: Breast Cancer Research and Treatment. 158, 3, p. 463-469 7 p.

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  • RAD51B in Familial Breast Cancer

    Pelttari, L. M., Khan, S., Vuorela, M., Kiiski, J. I., Vilske, S., Nevanlinna, V., Ranta, S., Schleutker, J., Winqvist, R., Kallioniemi, A., Doerk, T., Bogdanova, N. V., Figueroa, J., Pharoah, P. D. P., Schmidt, M. K., Dunning, A. M., Garcia-Closas, M., Bolla, M. K., Dennis, J., Michailidou, K., & 31 othersWang, Q., Hopper, J. L., Southey, M. C., Rosenberg, E. H., Fasching, P. A., Beckmann, M. W., Peto, J., dos-Santos-Silva, I., Sawyer, E. J., Tomlinson, I., Burwinkel, B., Surowy, H., Guenel, P., Truong, T., Bojesen, S. E., Nordestgaard, B. G., Benitez, J., Gonzalez-Neira, A., Neuhausen, S. L., Anton-Culver, H., Brenner, H., Arndt, V., Meindl, A., Schmutzler, R. K., Brauch, H., Bruening, T., Mattson, J., Blomqvist, C., Aittomäki, K., Nevanlinna, H. & kConFab-AOCS Investigators, 5 May 2016, In: PLoS One. 11, 5, 18 p., 0153788.

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  • Screening of HELQ in breast and ovarian cancer families

    Pelttari, L. M., Kinnunen, L., Kiiski, J. I., Khan, S., Blomqvist, C., Aittomaki, K. & Nevanlinna, H., Jan 2016, In: Familial Cancer. 15, 1, p. 19-23 5 p.

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  • 2015

    Common germline polymorphisms associated with breast cancer-specific survival

    Pirie, A., Guo, Q., Kraft, P., Canisius, S., Eccles, D. M., Rahman, N., Nevanlinna, H., Chen, C., Khan, S., Tyrer, J., Bolla, M. K., Wang, Q., Dennis, J., Michailidou, K., Lush, M., Dunning, A. M., Shah, M., Czene, K., Darabi, H., Eriksson, M., & 32 othersLambrechts, D., Weltens, C., Leunen, K., van Ongeval, C., Nordestgaard, B. G., Nielsen, S. F., Flyger, H., Rudolph, A., Seibold, P., Flesch-Janys, D., Blomqvist, C., Aittomaki, K., Fagerholm, R., Muranen, T. A., Olsen, J. E., Hallberg, E., Vachon, C., Knight, J. A., Glendon, G., Mulligan, A. M., Broeks, A., Cornelissen, S., Haiman, C. A., Henderson, B. E., Schumacher, F., Le Marchand, L., Hopper, J. L., Tsimiklis, H., Apicella, C., Southey, M. C., kConFab Investigators & NBCS Investigators, 22 Apr 2015, In: Breast Cancer Research. 17, 11 p., 58.

    Research output: Contribution to journal › Article › Scientific › peer-review

  • Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2

    Orr, N., Dudbridge, F., Dryden, N., Maguire, S., Novo, D., Perrakis, E., Johnson, N., Ghoussaini, M., Hopper, J. L., Southey, M. C., Apicella, C., Stone, J., Schmidt, M. K., Broeks, A., Van't Veer, L. J., Hogervorst, F. B., Fasching, P. A., Haeberle, L., Ekici, A. B., Beckmann, M. W., & 33 othersGibson, L., Aitken, Z., Warren, H., Sawyer, E., Tomlinson, I., Kerin, M. J., Miller, N., Burwinkel, B., Marme, F., Schneeweiss, A., Sohn, C., Guenel, P., Truong, T., Cordina-Duverger, E., Sanchez, M., Bojesen, S. E., Nordestgaard, B. G., Nielsen, S. F., Flyger, H., Benitez, J., Zamora, M. P., Perez, J. I. A., Menendez, P., Anton-Culver, H., Neuhausen, S. L., Brenner, H., Nevanlinna, H., Aittomaki, K., Blomqvist, C., Khan, S., GENICA Network , kConFab Investigators & Australian Ovarian Canc Study Grp , 15 May 2015, In: Human Molecular Genetics. 24, 10, p. 2966-2984 19 p.

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  • Fine-Scale Mapping of the 4q24 Locus Identifies Two Independent Loci Associated with Breast Cancer Risk

    Guo, X., Long, J., Zeng, C., Michailidou, K., Ghoussaini, M., Bolla, M. K., Wang, Q., Milne, R. L., Shu, X-O., Cai, Q., Beesley, J., Kar, S. P., Andrulis, I. L., Anton-Culver, H., Arndt, V., Beckmann, M. W., Beeghly-Fadiel, A., Benitez, J., Blot, W., Bogdanova, N., & 95 othersBojesen, S. E., Brauch, H., Brenner, H., Brinton, L., Broeks, A., Bruening, T., Burwinkel, B., Cai, H., Canisius, S., Chang-Claude, J., Choi, J-Y., Couch, F. J., Cox, A., Cross, S. S., Czene, K., Darabi, H., Devilee, P., Droit, A., Doerk, T., Fasching, P. A., Fletcher, O., Flyger, H., Fostira, F., Gaborieau, V., Garcia-Closas, M., Giles, G. G., Grip, M., Guenel, P., Haiman, C. A., Hamann, U., Hartman, M., Hollestelle, A., Hopper, J. L., Hsiung, C-N., Ito, H., Jakubowska, A., Johnson, N., Kabisch, M., Kang, D., Khan, S., Knight, J. A., Kosma, V-M., Lambrechts, D., Le Marchand, L., Li, J., Lindblom, A., Lophatananon, A., Lubinski, J., Mannermaa, A., Manoukian, S., Margolin, S., Marme, F., Matsuo, K., McLean, C. A., Meindl, A., Muir, K., Neuhausen, S. L., Nevanlinna, H., Nord, S., Olson, J. E., Orr, N., Peterlongo, P., Putti, T. C., Rudolph, A., Sangrajrang, S., Sawyer, E. J., Schmidt, M. K., Schmutzler, R. K., Shen, C-Y., Shi, J., Shrubsole, M. J., Southey, M. C., Swerdlow, A., Teo, S. H., Thienpont, B., Toland, A. E., Tollenaar, R. A. E. M., Tomlinson, I. P. M., Truong, T., Tseng, C., van den Ouweland, A., Wen, W., Winqvist, R., Wu, A., Yip, C. H., Zamora, M. P., Zheng, Y., Hall, P., Pharoah, P. D. P., Simard, J., Chenevix-Trench, G., Dunning, A. M., Easton, D. F., Zheng, W. & kConFab Investigators, Nov 2015, In: Cancer Epidemiology, Biomarkers & Prevention. 24, 11, p. 1680-1691 12 p.

    Research output: Contribution to journal › Article › Scientific › peer-review

  • Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

    Michailidou, K., Beesley, J., Lindstrom, S., Canisius, S., Dennis, J., Lush, M. J., Maranian, M. J., Bolla, M. K., Wang, Q., Shah, M., Perkins, B. J., Czene, K., Eriksson, M., Darabi, H., Brand, J. S., Bojesen, S. E., Nordestgaard, B. G., Flyger, H., Nielsen, S. F., Rahman, N., & 35 othersTurnbull, C., Fletcher, O., Peto, J., Gibson, L., dos-Santos-Silva, I., Chang-Claude, J., Flesch-Janys, D., Rudolph, A., Eilber, U., Behrens, S., Nevanlinna, H., Muranen, T. A., Aittomaki, K., Blomqvist, C., Khan, S., Aaltonen, K., Ahsan, H., Kibriya, M. G., Whittemore, A. S., John, E. M., Malone, K. E., Gammon, M. D., Santella, R. M., Ursin, G., Makalic, E., Schmidt, D. F., Casey, G., Hunter, D. J., Gapstur, S. M., Gaudet, M. M., BOCS, kConFab Investigators, AOCS Grp, NBCS & GENICA Network , Apr 2015, In: Nature Genetics. 47, 4, p. 373-U127 9 p.

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  • Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk

    Lin, W-Y., Camp, N. J., Ghoussaini, M., Beesley, J., Michailidou, K., Hopper, J. L., Apicella, C., Southey, M. C., Stone, J., Schmidt, M. K., Broeks, A., Van't Veer, L. J., Rutgers, E. J. T., Muir, K., Lophatananon, A., Stewart-Brown, S., Siriwanarangsan, P., Fasching, P. A., Haeberle, L., Ekici, A. B., & 34 othersBeckmann, M. W., Peto, J., Dos-Santos-Silva, I., Fletcher, O., Johnson, N., Bolla, M. K., Wang, Q., Dennis, J., Sawyer, E. J., Cheng, T., Tomlinson, I., Kerin, M. J., Miller, N., Marme, F., Surowy, H. M., Burwinkel, B., Guenel, P., Truong, T., Menegaux, F., Mulot, C., Bojesen, S. E., Nordestgaard, B. G., Nielsen, S. F., Flyger, H., Nevanlinna, H., Aittomäki, K., Blomqvist, C., Khan, S., Muranen, T. A., Heikkinen, T., GENICA Network , kConFab Investigators, Australian Ovarian Canc Study Grp & Breast Ovarian Canc Susceptibility, 1 Jan 2015, In: Human Molecular Genetics. 24, 1, p. 285-298 14 p.

    Research output: Contribution to journal › Article › Scientific › peer-review

  • Identification of Novel Genetic Markers of Breast Cancer Survival

    Guo, Q., Schmidt, M. K., Kraft, P., Canisius, S., Chen, C., Khan, S., Tyrer, J., Bolla, M. K., Wang, Q., Dennis, J., Michailidou, K., Lush, M., Kar, S., Beesley, J., Dunning, A. M., Shah, M., Czene, K., Darabi, H., Eriksson, M., Lambrechts, D., & 31 othersWeltens, C., Leunen, K., Bojesen, S. E., Nordestgaard, B. G., Nielsen, S. F., Flyger, H., Chang-Claude, J., Rudolph, A., Seibold, P., Flesch-Janys, D., Blomqvist, C., Aittomäki, K., Fagerholm, R., Muranen, T. A., Couch, F. J., Olson, J. E., Vachon, C., Andrulis, I. L., Knight, J. A., Glendon, G., Mulligan, A. M., Broeks, A., Hogervorst, F. B., Haiman, C. A., Henderson, B. E., Schumacher, F., Le Marchand, L., Hopper, J. L., Tsimiklis, H., Nevanlinna, H. & kConFab Investigators, May 2015, In: Journal of the National Cancer Institute. 107, 5, 9 p., 081.

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  • INPP4B and RAD50 have an interactive effect on survival after breast cancer

    Dai, X., Fagerholm, R., Khan, S., Blomqvist, C. & Nevanlinna, H., Jan 2015, In: Breast Cancer Research and Treatment. 149, 2, p. 363-371 9 p.

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  • Polymorphism at 19q13.41 Predicts Breast Cancer Survival Specifically after Endocrine Therapy

    Khan, S., Fagerholm, R., Rafiq, S., Tapper, W., Aittomaki, K., Liu, J., Blomqvist, C., Eccles, D. & Nevanlinna, H., 15 Sep 2015, In: Clinical Cancer Research. 21, 18, p. 4086-4096 11 p.

    Research output: Contribution to journal › Article › Scientific › peer-review

  • Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression

    Darabi, H., Mccue, K., Beesley, J., Michailidou, K., Nord, S., Kar, S., Humphreys, K., Thompson, D., Ghoussaini, M., Bolla, M. K., Dennis, J., Wang, Q., Canisius, S., Scott, C. G., Apicella, C., Hopper, J. L., Southey, M. C., Stone, J., Broeks, A., Schmidt, M. K., & 32 othersScott, R. J., Lophatananon, A., Muir, K., Beckmann, M. W., Ekici, A. B., Fasching, P. A., Heusinger, K., dos-Santos-Silva, I., Peto, J., Tomlinson, I., Sawyer, E. J., Burwinkel, B., Marme, F., Guenel, P., Truong, T., Bojesen, S. E., Flyger, H., Benitez, J., Gonzalez-Neira, A., Anton-Culver, H., Neuhausen, S. L., Arndt, V., Brenner, H., Engel, C., Meindl, A., Schmutzler, R. K., Arnold, N., Brauch, H., Khan, S., Nevanlinna, H., German Consortium Hereditary Breas & kConFab-AOCS Investigators, 2 Jul 2015, In: American Journal of Human Genetics. 97, 1, p. 22-34 13 p.

    Research output: Contribution to journal › Article › Scientific › peer-review

  • SNP-SNP interaction analysis of NF-kappa B signaling pathway on breast cancer survival

    Jamshidi, M., Fagerholm, R., Khan, S., Aittomaki, K., Czene, K., Darabi, H., Li, J., Andrulis, I. L., Chang-Claude, J., Devilee, P., Fasching, P. A., Michailidou, K., Bolla, M. K., Dennis, J., Wang, Q., Guo, Q., Rhenius, V., Cornelissen, S., Rudolph, A., Knight, J. A., & 38 othersLoehberg, C. R., Burwinkel, B., Marme, F., Hopper, J. L., Southey, M. C., Bojesen, S. E., Flyger, H., Brenner, H., Holleczek, B., Margolin, S., Mannermaa, A., Kosma, V-M., Van Dyck, L., Nevelsteen, I., Couch, F. J., Olson, J. E., Giles, G. G., McLean, C., Haiman, C. A., Henderson, B. E., Winqvist, R., Pylkas, K., Tollenaar, R. A. E. M., Garcia-Closas, M., Figueroa, J., Hooning, M. J., Martens, J. W. M., Cox, A., Cross, S. S., Simard, J., Dunning, A. M., Easton, D. F., Pharoah, P. D. P., Hall, P., Blomqvist, C., Schmidt, M. K., Nevanlinna, H. & kConFab Investigators, 10 Nov 2015, In: Oncotarget. 6, 35, p. 37979-37994 16 p.

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  • The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients

    Fagerholm, R., Schmidt, M. K., Khan, S., Rafiq, S., Tapper, W., Aittomaki, K., Greco, D., Heikkinen, T., Muranen, T. A., Fasching, P. A., Janni, W., Weinshilboum, R., Loehberg, C. R., Hopper, J. L., Southey, M. C., Keeman, R., Lindblom, A., Margolin, S., Mannermaa, A., Kataja, V., & 27 othersChenevix-Trench, G., Lambrechts, D., Wildiers, H., Chang-Claude, J., Seibold, P., Couch, F. J., Olson, J. E., Andrulis, I. L., Knight, J. A., Garcia-Closas, M., Figueroa, J., Hooning, M. J., Jager, A., Shah, M., Perkins, B. J., Luben, R., Hamann, U., Kabisch, M., Czene, K., Hall, P., Easton, D. F., Pharoah, P. D. P., Liu, J., Eccles, D., Blomqvist, C., Nevanlinna, H. & kConFab Investigators, 10 Apr 2015, In: Oncotarget. 6, 10, p. 7390-7407 18 p.

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  • 2014

    A Genome Wide Meta-Analysis Study for Identification of Common Variation Associated with Breast Cancer Prognosis

    Rafiq, S., Khan, S., Tapper, W., Collins, A., Upstill-Goddard, R., Gerty, S., Blomqvist, C., Aittomaki, K., Couch, F. J., Liu, J., Nevanlinna, H. & Eccles, D., 2014, In: PLoS One. 19, 12, 10 p., e101488.

    Research output: Contribution to journal › Article › Scientific

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  • Breast-Cancer Risk in Families with Mutations in PALB2

    Antoniou, A. C., Casadei, S., Heikkinen, T., Barrowdale, D., Pylkaes, K., Roberts, J., Lee, A., Subramanian, D., De Leeneer, K., Fostira, F., Tomiak, E., Neuhausen, S. L., Teo, Z. L., Khan, S., Aittomaki, K., Moilanen, J. S., Turnbull, C., Seal, S., Mannermaa, A., Kallioniemi, A., & 28 othersLindeman, G. J., Buys, S. S., Andrulis, I. L., Radice, P., Tondini, C., Manoukian, S., Toland, A. E., Miron, P., Weitzel, J. N., Domchek, S. M., Poppe, B., Claes, K. B. M., Yannoukakos, D., Concannon, P., Bernstein, J. L., James, P. A., Easton, D. F., Goldgar, D. E., Hopper, J. L., Rahman, N., Peterlongo, P., Nevanlinna, H., King, M. -C., Couch, F. J., Southey, M. C., Winqvist, R., Foulkes, W. D. & Tischkowitz, M., 7 Aug 2014, In: New England Journal of Medicine. 371, 6, p. 497-506 10 p.

    Research output: Contribution to journal › Article › Scientific › peer-review

  • Breast-Cancer Risk in Families With Mutations in PALB2 EDITORIAL COMMENT

    Antoniou, A. C., Casadei, S., Heikkinen, T., Barrowdale, D., Pylkas, K., Roberts, J., Lee, A., Subramanian, D., de Leeneer, K., Fostira, F., Tomiak, E., Neuhausen, S. L., Teo, Z. L., Khan, S., Aittomaki, K., Moilanen, J. S., Turnbull, C., Seal, S., Mannermaa, A., Kallioniemi, A., & 28 othersLindeman, G. J., Buys, S. S., Andrulis, I. L., Radice, P., Tondini, C., Manoukian, S., Toland, A. E., Miron, P., Weitzel, J. N., Domchek, S. M., Poppe, B., Claes, K. B. M., Yannoukakos, D., Concannon, P., Bernstein, J. L., James, P. A., Easton, D. F., Goldgar, D. E., Hopper, J. L., Rahman, N., Peterlongo, P., Nevanlinna, H., King, M-C., Couch, F. J., Southey, M. C., Winqvist, R., Foulkes, W. D. & Tischkowitz, M., Nov 2014, In: Obstetrical & Gynecological Survey. 69, 11, p. 659-660 2 p.

    Research output: Contribution to journal › Article › Scientific

  • Evaluation of the RHINO gene for breast cancer predisposition in Finnish breast cancer families

    Heikkinen, T., Khan, S., Huovari, E., Vilske, S., Schleutker, J., Kallioniemi, A., Blomqvist, C., Aittomaki, K. & Nevanlinna, H., Apr 2014, In: Breast Cancer Research and Treatment. 144, 2, p. 437-441 5 p.

    Research output: Contribution to journal › Article › Scientific › peer-review

  • Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer

    Kiiski, J., Pelttari, L. M., Khan, S., Freysteinsdottir, E. S., Reynisdottir, I., Hart, S. N., Shimelis, H., Vilske, S., Kallioniemi, A., Schleutker, J., Leminen, A., Butzow, R., Blomqvist, C., Barkardottir, R. B., Couch, F. J., Aittomaki, K. & Nevanlinna, H., 21 Oct 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 42, p. 15172-15177 6 p.

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  • MicroRNA Related Polymorphisms and Breast Cancer Risk

    Khan, S., Greco, D., Michailidou, K., Milne, R. L., Muranen, T. A., Heikkinen, T., Aaltonen, K., Dennis, J., Bolla, M. K., Liu, J., Hall, P., Irwanto, A., Humphreys, K., Li, J., Czene, K., Chang-Claude, J., Hein, R., Rudolph, A., Seibold, P., Flesch-Janys, D., & 33 othersFletcher, O., Peto, J., Silva, I. D. S., Johnson, N., Gibson, L., Aitken, Z., Hopper, J. L., Tsimiklis, H., Bui, M., Makalic, E., Schmidt, D. F., Southey, M. C., Apicella, C., Stone, J., Waisfisz, Q., Meijers-Heijboer, H., Adank, M. A., van der Luijt, R. B., Meindl, A., Schmutzler, R. K., Muller-Myhsok, B., Lichtner, P., Turnbull, C., Rahman, N., Chanock, S. J., Hunter, D. J., Cox, A., Blomqvist, C., Aittomaki, K., Nevanlinna, H., kConFab Investigators, Australian Ovarian Canc Study Grp & GENICA Network , 12 Nov 2014, In: PLoS One. 9, 11, 12 p., 109973.

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  • 2013

    COMPLEXO: identifying the missing heritability of breast cancer via next generation collaboration

    Southey, M. C., Park, D. J., Nguyen-Dumont, T., Campbell, I., Thompson, E., Trainer, A. H., Chenevix-Trench, G., Simard, J., Dumont, M., Soucy, P., Thomassen, M., Jonson, L., Pedersen, I. S., Hansen, T. V. O., Nevanlinna, H., Khan, S., Sinilnikova, O., Mazoyer, S., Lesueur, F., Damiola, F., & 37 othersSchmutzler, R., Meindl, A., Hahnen, E., Dufault, M. R., Chan, T. C., Kwong, A., Barkardottir, R., Radice, P., Peterlongo, P., Devilee, P., Hilbers, F., Benitez, J., Kvist, A., Torngren, T., Easton, D., Hunter, D., Lindstrom, S., Kraft, P., Zheng, W., Gao, Y-T., Long, J., Ramus, S., Feng, B-J., Weitzel, R. N., Nathanson, K., Offit, K., Joseph, V., Robson, M., Schrader, K., Wang, S. M., Kim, Y. C., Lynch, H., Snyder, C., Tavtigian, S., Neuhausen, S., Couch, F. J. & Goldgar, D. E., 2013, In: Breast Cancer Research. 15, 3, 2 p., 402.

    Research output: Contribution to journal › Article › Scientific