Research Output per year
Personal profile
Description of research and teaching
I am currently pursuing my Ph.D. degree at the Doctoral Programme for Chemistry and Molecular Sciences (CHEMS-DP) in The TRacers for Molecular Imaging Team (TRIM Team). The project I am working on is an Academy of Finland Key project (Prof. Airaksinen) on KIT-radiolabeling of biomolecules with fluorine-18 under the supervision of Prof. Airaksinen and Dr. Sarparanta. My research interests are on targeted biopharmaceutics, personalized medicines and studying cancer and its differentiation from benign conditions. Thus, the main focus of my PhD is on developing efficient radiolabeling methods for functionalized biopharmaceuticals. The aim in my project is on the utilization of the radiolabeled analogues of these selected biomolecules to target and evaluate the biomolecular tracers in a variety of cancers in murine xenograft and allograft tumor models. In my research I use biological evaluations and positron emission tomography (PET) with fluorine-18 radiolabeled biomolecules for the detection of cancers in a molecular and cellular level.
Keywords
- 116 Chemical sciences
International and National Collaboration
Publications and projects within past five years.
Publications 2019 2019
- 1 Article
Radiolabeled Molecular Imaging Probes for the in Vivo Evaluation of Cellulose Nanocrystals for Biomedical Applications
Imlimthan, S., Otaru, S., Keinänen, O., Correia, A., Lintinen, K., Almeida Santos, H., Airaksinen, A., Kostiainen, M. & Sarparanta, M., Feb 2019, In : Biomacromolecules. 20, 2, p. 674–683 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
Projects 2016 2020
PRERAPHA: Pretargeted radiopharmaceuticals for imaging
Airaksinen, A., Sarparanta, M., Lumen, D., Lambidis, E. & Otaru, S.
01/09/2016 → 31/08/2020
Project: Research project
Efficient, biocompatible and selective [18F]-fluorination reagents for kit production of PET radiopharmaceuticals.
Otaru, S., Airaksinen, A. & Keinänen, O.
01/10/2016 → 30/09/2018
Project: Research project
Activities 2017 2019
17th Nordic Mass Spectrometry Conference (Oral presentation): High-resolution mass spectrometry-based investigation of defluorination of a novel PET radiotracer
Sofia Otaru (Speaker)26 Aug 2019 → 28 Aug 2019
Activity: Talk or presentation types › Oral presentation
23rd International Symposium on Radiopharmaceutical Sciences (ISRS) (Poster presentation): "Investigation of the Metabolic Stability of New Silicon-Based Fluoride Acceptor 18F-Tracers"
Sofia Otaru (Poster Presentation)26 May 2019 → 1 Jun 2019
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Ph.D. representative in the steering group of doctoral program in Chemistry and Molecular Sciences (CHEMS) 2018- (Event)
Sofia Otaru (Member)1 Jan 2018 → 31 Dec 2019
Activity: Membership types › Membership or other role in research network
Medicinal Chemistry Meets Pharmacology Symposium
Sofia Otaru (Attendee)24 Apr 2018 → 25 Apr 2018
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
World Molecular Imaging Congress (WMIC) (Poster presentation): "Synthesis of a 18F-Labeled Tetrazine for Pretargeted PET-Applications"
Sofia Otaru (Poster Presentation)13 Sep 2017 → 16 Sep 2017
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars