Research output per year
Research output per year
Personal profile
Education/Academic qualification
Chemistry, M.Sc., University of Helsinki
Award Date: 1 Jun 2017
Radiopharmaceutical Chemistry, Ph.D., University of Helsinki
22 Aug 2017 → …
Fields of Science
- 116 Chemical sciences
- molecular imaging
- positron emission tomography
- preclinical
- radiopharmaceutical chemistry
- biological radiopharmaceutics
- click chemistry
- bioorthogonal chemistry
International and National Collaboration
Publications and projects within past five years.
Publications
- 4 Article
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Development of [18F]AmBF3 Tetrazine for Radiolabeling of Peptides: Preclinical Evaluation and PET Imaging of [18F]AmBF3-PEG7-Tyr3-Octreotide in an AR42J Pancreatic Carcinoma Model
Otaru, S., Paulus, A., Imlimthan, S., Kuurne, I., Virtanen, H., Liljenbäck, H., Tolvanen, T., Auchynnikava, T., Roivainen, A., Helariutta, K., Sarparanta, M. & Airaksinen, A., 16 Jun 2022, In: Bioconjugate Chemistry. 33, 7, p. 1393-1404 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Evaluation of Organo [F-18]Fluorosilicon Tetrazine as a Prosthetic Group for the Synthesis of PET Radiotracers
Otaru, S., Imlimthan, S., Sarparanta, M., Helariutta, K., Wähälä, K. & Airaksinen, A., 1 Mar 2020, In: Molecules. 25, 5, 17 p., 1208.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Metabolism of a Bioorthogonal PET Tracer Candidate [F-19/F-18]SiFA-Tetrazine in Mouse Liver Microsomes: Biotransformation Pathways and Defluorination Investigated by UHPLC-HRMS
Otaru, S., Niemikoski, H., Sarparanta, M. & Airaksinen, A. J., 3 Aug 2020, In: Molecular Pharmaceutics. 17, 8, p. 3106-3115 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
Radiolabeled Molecular Imaging Probes for the in Vivo Evaluation of Cellulose Nanocrystals for Biomedical Applications
Imlimthan, S., Otaru, S., Keinänen, O., Correia, A., Lintinen, K., Almeida Santos, H., Airaksinen, A., Kostiainen, M. & Sarparanta, M., Feb 2019, In: Biomacromolecules. 20, 2, p. 674–683 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Efficient, biocompatible and selective [18F]-fluorination reagents for kit production of PET radiopharmaceuticals.
Otaru, S., Airaksinen, A. & Keinänen, O.
01/10/2016 → 30/09/2018
Project: Research project
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PRERAPHA: Pretargeted radiopharmaceuticals for imaging
Airaksinen, A., Sarparanta, M., Lumen, D., Lambidis, E. & Otaru, S.
01/09/2016 → 31/08/2020
Project: Research project
Activities
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23rd International Symposium on Radiopharmaceutical Sciences (ISRS) (Poster presentation): "Investigation of the Metabolic Stability of New Silicon-Based Fluoride Acceptor 18F-Tracers"
Sofia Otaru (Poster Presentation)
26 May 2019 → 1 Jun 2019Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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17th Nordic Mass Spectrometry Conference (Oral presentation): High-resolution mass spectrometry-based investigation of defluorination of a novel PET radiotracer
Sofia Otaru (Speaker)
26 Aug 2019 → 28 Aug 2019Activity: Talk or presentation types › Oral presentation
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Ph.D. representative in the steering group of doctoral program in Chemistry and Molecular Sciences (CHEMS) 2018- (Event)
Sofia Otaru (Member)
1 Jan 2018 → 31 Dec 2019Activity: Membership types › Membership or other role in research network
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Medicinal Chemistry Meets Pharmacology Symposium
Sofia Otaru (Attendee)
24 Apr 2018 → 25 Apr 2018Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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XIV Turku PET Symposium (Poster presentation): "Synthesis of a 18F-Labeled Tetrazine via Isotopic Exchange for Pretargeted PET Imaging"
Sofia Otaru (Poster Presentation)
27 May 2017 → 30 May 2017Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars