Research output per year
Research output per year
Personal profile
Education information
M.Sc.Education/Academic qualification
Master of Science, University of Helsinki
Fields of Science
- 1182 Biochemistry, cell and molecular biology
- 1183 Plant biology, microbiology, virology
- 1184 Genetics, developmental biology, physiology
- 3122 Cancers
- Translational research
- Personalized Medicine
- 318 Medical biotechnology
- 116 Chemical sciences
- drug screening
International and National Collaboration
Publications and projects within past five years.
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Designing patient-oriented combination therapies for acute myeloid leukemia based on efficacy/toxicity integration and bipartite network modeling
Mirzaie, M., Gholizadeh, E., Miettinen, J. J., Ianevski, F., Ruokoranta, T., Saarela, J., Manninen, M., Miettinen, S., Heckman, C. A. & Jafari, M., 1 Mar 2024, In: Oncogenesis. 13, 1, 12 p., 11.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Ex vivo venetoclax sensitivity predicts clinical response in acute myeloid leukemia in the prospective VenEx trial
Kytölä, S., Vänttinen, I. M., Ruokoranta, T., Partanen, A., Holopainen, A., Saad, J., Kuusisto, M. E. L., Koskela, S., Räty, R., Itälä-Remes, M., Västrik, I., Suvela, M., Parsons, A. O., Porkka, K., Wennerberg, K., Heckman, C. A., Jalkanen, T., Huttunen, T., Ettala, P. & Rimpiläinen, J. & 4 others, , 2024, In: Blood.Research output: Contribution to journal › Article › Scientific › peer-review
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Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones
Ianevski, A., Nader, K., Driva, K., Senkowski, W., Bulanova, D., Moyano-Galceran, L., Ruokoranta, T., Kuusanmäki, H., Ikonen, N., Sergeev, P., Vähä-Koskela, M., Giri, A. K., Vähärautio, A., Kontro, M., Porkka, K., Pitkänen, E., Heckman, C. A., Wennerberg, K. & Aittokallio, T., Dec 2024, In: Nature Communications. 15, 1, 16 p., 8579.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Venetoklaksiherkkyys ennustaa leukemian hoidon vastetta
Translated title of the contribution :Ex vivo venetoclax sensitivity predicts clinical response in acute myeloid leukemia in the Prospective VenEx Trial Research output: Contribution to journal › Comment/debate › Professional
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BCL-2/BCL-XL Inhibition Induces Apoptosis and Circumvents Venetoclax Resistance in TP53-mutated Acute Myeloid Leukemia
Vänttinen, I. M., Kytölä, S. J., Dufva, O., Hellesøy, M., Gullaksen, S.-E., Ruokoranta, T., Bruck, O., Siitonen, S., Ettala, P., Pyörälä, M., Rimpilainen, J., Siitonen, T., Gjertsen, B. T., Heckman, C., Kuusanmäki, H. & Kontro, M., 8 Aug 2023, In: Hemasphere.Research output: Contribution to journal › Meeting Abstract › peer-review
Projects
- 1 Active
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Caroline Heckman NIH subaward ISB
Heckman, C. (Project manager), Kallio, S. J. (Participant), Kuusanmäki, H. (Participant), Miettinen, J. (Participant), Olgac, E. J. (Participant), Parsons, A. O. (Participant), Ruokoranta, T. (Participant), Sergeev, P. (Participant) & Srivastava, A. (Participant)
National Institutes of Health (NIH) OFM
01/01/2023 → 31/12/2024
Project: Other funder